Pharmacrystalwww.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) Pharmacrystal GPAT Mock 5 1. Kovats indices ,Rohrschneider constants Mcreynolds constants are useful in selection of A .Stationary phase B. Mobile phase C. Detector D no 2. Virus should be classified as a. Akaryotic b. Eukaryotic c. Prokaryotic d. Nokaryotic 3. Which of the following is a BBB permeation enhancer? A.Cyclic amide B.Diethyl nitrate C.Dimethyl sulfoxide D.Mannitol 4. wich of the following drugs cont. inulin? A. Cichoriae radix B. Comfrey root C. plantain shoot D. Tanaceti herb 5. Bracetain is A.Chalcone B.Flavanol C.Aurones D.Isoflavone 6. Mean Corpuscular volume is: A.Hemoglobin/erythrocyte count B.Hemoglobin/hematorcit C.Hematocrit/erythrocyte count D.Hematocrit/hemoglobin 7. Oral bioavailability of griseofulvin is increased by A.Micronization B.Solid dispersion Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) CAmorphous generation D.None 8. Nystatin is obtained from: A.S.nouresi B.S.rimosus C.M.purpura D.B.subtlis 9. If the molar concentration and molecular weight are 4 x 10-4 and 56.06 respect. its conc. In gm/ml is A.2.5 x 10-6 B.0.25 x 10-6 C.5 x 10 D.B.subtlis 10. The killed polio vaccine is: A.Salk vaccine B.Sabin vaccine C.APT D.All of the above 11. Adduct peak occurs due to: A.Metastable ion B.Molecular ion C.Fragments of compound D.Impurity 12. Linezolid contains ring called as: A.oxazolidinedione B.oxazole C.azole D.oxazolidine 13. Which isomer of 'stilboestrol' is more active? A.Trans B.Cis C.Both D.None 14. Active constituent of fennel responsible for camphoraceous taste is A.Anethole Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) B.Anisldehyde C.Fenchone D.Methy Chavicol 15. Dense pseudo-parechymatous cells of Ergot is composed of _________ A.Cellular B.Starch C.Chitin D.Inulin 16. Drug possessing anti oxidant action is A.Pramipaxol B.Cloquinol C.Pargolide D.Lisuride 17. AUMC is A.Area under mean curv B.Area under first stastical moment curve C.Area under mol fraction curve D.Area under monogram curve 18. The osmolarity of plasma is: A.410 mosm/l B.306 mosm/l <280-310> C.200 mosm/l D.350 mosm/l 19. Ergot shud possess water soluble ergometerine not less than a) 0.19% b) 15% c) 1.2% d) 0.15% 20. one drug cn paralyse taste buds a) shatavari b) gymnema c) asafoetida d) capsicum 21. Sweet taste of senega is due to a) methyl salicylate b) senegin c) polygallitol d) ophellic acid 22. prazocin & vasacinone possess same basic ring a) pyrazole b) piperazine c) quinazoline d) dihydro pyridine. 23. yellow color of liquorice is due to a) carbenoxlone b) glycerhizin c) liquiritin d) glycerhetinic acid. Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) 24. Ring having anti-malarial activity is a) imidazole b) quinazoline c) quinoline d) isoquinoline 25."Male fern" is a) Trychyspermum copticum b) Apium graveolens c) Dryopteris odorata d) Dryopteris fleximass. 26. Quantitative color estimation of tablets is done by: 1.microreflectance photometry 2.tristimulus 3.colorimetry 4.reflectance spectrophotom 27. Balsamic acid is the combination of acids a) benzoic + salicylic b) salicylic + shikimic c) benzoic + cinnamic d) salicylic + cinnamic. 28. drug causing anti cancer action by promoting defected microtubule formation is a) paclitaxal b) topotecan c) etoposide d) vincristine. 29. Causative organism of syphilis is a.Trichuris trichuri b.Trichomonas dimanata c.Lechmenia donovanni d.Trypanosoma gambiense 30. Number of double bonds are determined by? a.H2 b.Br2 c.Ozonolysis d.all 31. Iliac horns are seen in A)Nail patella syndrome B)ankylossing spondyliti C)Both answer 1 and 2 Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) D)None of these 32. Adverse effect of terfenadine include A)Ventricular tachycardia B)Bradycardia C)Hepatotoxicity D)Neurotoxicity 33. all drugs contains enzymes except a) Dioscorea deltoida b) Digitalis purpurea c) Allium sativum d) Prunus amygdalin e) Taxus brevifolia. 34. haracterstic smell of cocaine powder is due to a) methyl salicylate b) ethyl acetate c) coumarin d) methyl benzoate. 35. "Carbenoxlone" is a) tetracyclic triterpenoid b) enolate c) steroidal d) pentacyclictriterpenoid.ystrdy 36. An active constituent of "Lacifera lecca"(i.e shellac) plays an important role in tablet a) seal coatingb) sub coating c) smoothing d) polishing 37. an active constituent of "Artemisia pallens" is a) santonin b) artemisinin c) davanone d) artemisin e) all. 38. Sennosides can be assigned trans/meso depending on position a) 9-10' b) 10-10' c) 1-8' d) 8-10'. 39. Shikimic acid" can be extracted out from the species of plants a) Panax ginseng b) Coleus blumei c)Galium mullugo d) Suringa vulgaris. 40. warty outgrowth from micropyle is a) strophiole b) caruncle c) arillode d) aristha 41. red color with nitric acid is the characterstic test of a) mucilage b) cellulose c) medulary rays d) mesophyll cells. 42. cisapride is a) prodrug of loperamide b) 5 HT agonist c) sulfonamide used with dapsone in laprosy Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) d) GABA agonist. 43. Number of IR peaks given by N=O? a.1 b.2 c.3 d.4 44. Drug used in quinidine toxicity? a.N acetylcystine b.Na lactate c.Fe d.digitalis 45. Drug of choice for dermatitis herpatiformis a.sulfadoxine b. c.dapsone d.amoxicillin 46. Drug used in cyanide poisoning? a.amiodarone b.EDTA c.N-acetylcystiene d.amyl nitrate 47. maximum activity of sulphonamides is observed between pKa values: a.5.6-6.5 b.5.1-5.9 c.6.6-7.4 d.6.8-8.2 48. Which one is best suited combinatn of crude drugs 4 Lycopodium Spore Method? a. Clove & Senna b. Senna & Aloe c. Ginger & Cardamon d.Clove & cinnamom 49. Which one is Nonionic surfactant: A.Fatty alcohols B.Cetyl alcohol C.Stearyl alcohol D.all.. Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) 50. an inj formd by recombinant DNA technlogy a) streptokinase b) alteplase c) urokinase d) seratiopeptidse 51. C6-C3-C6 ring system is present in a) quercetin b) vitamin A c) xanthophyll d) poligalitol 52. ZINGIBERENE is which type of sesquiterpene? a) acyclic b) monocyclic c) bicyclic d) tricyclic.ystrday ans withaferin 53. best sterilisation method to sterilise a "Lab coat" is a) gaseous b) moist heat c) ionising radiation d) non ionising radiation 54. Steroid nucleus+ 6 membrd lactone ring present in a) conessine b) digoxin c) withaferin d) guggalsterol. 55. WCH compd used as MP in supercritical fluid chromatogrphy? a)H2O b)Benzene c)CO2 d)both a&c 56. Indian father of QSAR is currntly teaching in a) DIPSAR b) NIPER mohali c) NIPER rayebreli d) PUNJAB UNIVERSITY e) JAMIA HAMDARD university. 57. In +nce of Hydrofluoric acid (H2F4), Nitric acid acts as A.Lowry-Bronsted acid. B.L-B base C.both A & B D.Neutral solvent 58. Unit of perfusion rate is a) Ml/Min b) Ml/Min/Ml c) Ml/Min/kg d) mcg/Ml. 59. Sulfonamides & NSAID's causes "Kernicterus" by replacing from the receptor site Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) a) albumin b) glycoprotein c) bilirubin d) globulin. 60. Bioavailability,F= a) AUC oral/AUC iv b) AUC iv/AUC oral c) Clearance/AUC oral d) AUC iv/Vd. 61. blockers of receptor not in clinical use is a) beta 1 b) beta 2 c) Nm d) H3 62. Scoline apnea is associated with a) tetracyclin b) thiazides c) phenytoin d) succinyl cholines 63. flumazenil can displace frm receptor site a) diazeapm b) diclofenac c) pioglitazone d) sulfonamides. 64. Hydralazine is a) K channel blocker b) Na channel blocker c) Na channel opener d) K channel opener 65. insulin is obtained frm a) hourse b) fish c) pork d) beef e) both 66. Metallic taste is experienced with all except 1. Metronidazole 2. Ciprofloxacin 3. Azithromycin 4. Nystatin 67. mysthenia is aggravatd by a) streptomycin b) ofloxacin c) phenytoin d) all 68. onset of action of NO is a) 5 min b) 5 sec c) 2 min d) 50 sec 69. the category of drugs having origin frm viper snake poison "teprotide "is a) CCB b) ACE inhibitor c) EDRF Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) 70. One drug is obtaind frm kidney a) urokinase b) streptokinase c) alteplase d) seratiopeptidase 71. ____isomer of doxepin is active a)(Z-) b)(R) c)(s) d)none of above 72. Skin temp for suppository prep. 'c a)25 b)32 c)37 d)2 73. Echinocandins inhibit the synthesis of a)1,6 b-glucan b)1,3 b-glucan c)1,4-a-glucan d)1,6-a-glucan 74. Buck Wheat mainly contains rutin that is obtained from a) Fagopyrum esculentum b) Dipteryx odorata c) Silybum marianum d) Gingko 75. which of the folowing is substrate for P-glycoprotein. A)aspirin B)cetrizine c)epinephrine D)digoxin 76. Calcium oxalate crystals in Rauwolfia root are a) Prismatic b) Cluster c) Acicular d) Rosette 77. Aniline (aminobenzene) is made by (a) direct amination (b) nitration and oxidation (c) nitration and reduction (d) sulfonation and reduction Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) 78. Basal thermometer is used for a)Temp Determination b)Estim of time ovuation c)Consistency of pharma products d) Stability 79. The ratio of cell constant and resistance in Conductometric titration is known as a) EMF b) Specific conductance c) Standard potential d) none of 80. Mass-Mass spectrometer is also known as a) Double focusing b) Electrospray desorption c) Tandem d) Quadrupol 81. Which one of the following factors does not affect the chemical shift? a) Inductive effect b) Anisotropic effect c) Concentration d) hydrogen bond 82. IPECA is related with a) Excipients b) Carbohydrates c) Proteins d) Extractio 83. Lipitor is brand name of atorvastatin; is best selling drug product by a) Eli Lilly b) Pfizer c) Glaxo d) Sanofi 84. The Claisen condensation reaction between methyl formate and methyl acetate gives a (a) diketone (b) diester (c) ketoester (d) aldoester 85. Resonance energy results from (a) sharing electrons (b) overlapping p orbitals (c) conjugation (d) all of the above 86. An enol-keto equilibrium is usually shifted toward (a) the enol form (b) the keto form (c) equally in both directions Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) (d) no equilibrium exists 87. Which combination is a diastereometric pair? (a) 2S, 3S and 2S, 3S (b) 2S, 3S and 2R, 3R (c) 2S, 3S and 2S, 3R (d) 2S, 3R and 2R, 3S 88. Homolytic bond cleavage gives (a) cations (b) anions (c) radicals (d) cations and anions 89. Which one of the follow is chiral? A)A hammer B) A candle C) A catcher's mitt D) A screwdriver 90. For unexpected polymorphism which receptor is responsible (A) D1 Reptor (B) D2 Rptor (C)D3 Reptor (D) D4 Rptor 91. lysuride is a a) D1 agonist b) D2 agonist c) agonist of both d) D1 antagonist.ans-c) 92. all act thrugh tyrosine kinase receptors except a) Growth factors b) thyroid hormone c) insulin d) cytokines. 93. in arsenic poisoning excess arsenic shows chronic effect after binding to a) SH b) NH2 c) C=O d) OH 94. The causes of hyperkalaemia include: A) Renal failure. B) Mineralocorticoid deficiency. C) Acidosis D) Potassium release from damaged cells 95. Interparticular force is related to Contact At:
[email protected] Pharmacrystal www.pharmacrystalniper.blogsport.com All Materials are prepared by NIPER Students (Mohali) a)Griffin b)Sorensen c)DLSO theory d)Ostwald ripening 96. Dienoesterol is synthesized from a)4-hydroxy propiophenone b)4-amino acetophenone c)4-hydroxy butyrophenone d)4-bromo propiophenone 97. Kaolin is chemically a)hydrated magnesium silicate b)hydrated aluminium silicate c)hydrated calcium silicate d)hydrated magnesium sulpha 98. dipeptidyl peptidase-4 (DPP-4) and are a potent treat for type 2 diabe: a) Vildagliptin b) Saxagliptin c) Denagliptin d) Azetidine based compound 99. Which of the following drugs is the first line choice for treatment of hypertension a. Monopril b. Diltiazem c. Betaxolol d. Quinidine 100. lente insulin is actually A.regular soluble insulin B.recombinant insulin C.insulin zinc suspension D.insulin complexed with protamine Pharmacrystal: Mail:
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