1- The major action of sodium chromoglycate is : mast cellstabilization . 2- The action of histamine is : stimulation of gastric secretion 3- One of the following antibiotics is resistant to penicillinase : floxapen ( flucloxacillin 4- Inderal is : pure b -adrenergic receptor blocker 5- Rifampicin is indicated for treatment of : tuberculosis 6- Which of the following is selective b1 blocker : labetalol but it is non selective b blocker 7- The latabbreviation for " After Meals " is : p.c 8- The latin abbreviation for " Four Times Daily " is : q.i.d 9- The latin abbreviation for " Every Night " is : o.n 10- Erythroped A : is effective against G +ve Cocci >>and G –ve bacteria, is a macrolide antibioticc -can increase g.i.t. motility, could be used in pregnant women if need, 11- For the treatment of anaphylactic shock use : epinephrine 12- Allopurinol is used as : agent which increases renal tubular reabsorption 13- Which of the following is NOT betamethasone side effect : hypoglycemia 14- A disease which is due to viral infection : poliomyelitis , rabies, chicken pox , herpes 15- The mechanism of action of atropine is : muscarinic antagonist 16- Myocardial muscle tissue property to generate electrical is : automaticity 17- The heart`s dominant pacemaker is : SA node supraventricular tachycardia 19- Adenosine P produces which of the following : dyspnea 20- Which of the following is responcible for buffering : bicarbonates 21-Respiratory acidosis is due to : CO2 retention 22 - Which of the following is NOT colloid solution : ringer`s solution 23- The term shock signifies : hypoperfusion 24- In treatment of shock , which of the following should be considered : airway control , IV of crystalloid solution , dopamine to support blood pre ssure , monitor heart rhythm 25- Which of the following is released by bacterial infection?(…. by bacterial cell wall duringthere growth ) : exotoxin 26- the amount of water in adult male is about : 60% 27-Which of the following are causes of oedema : increase hydrostatic pressure , decrease oncotic pressure , increase capillary permeability 28 -Patients prescribed non reversible monoamine oxidase inhibitor should be advised not to consume food containing tyramine because this combination causes : acute adrenergic crisis including sever hypertention 29 -Concerning COX 2 inhibitors , which is NOT true : 30- osteoporosis which of the following is NOT true : alendronate should be taken 60 min. before breakfast 31- Which of the following is the first choice in acute gout : 32 -Which of the following is NOT a risk factor for osteoparalys is : male gender 33- Early symptoms of aspirin poisoning are : ringing in the ears & blurred vision 34 -Which of the following is NOT true about infiximab : 35- A disease modifying drugs in rheumatoid arthritis : gold preparations , hydroxychloroquine , methotrexate . 36- A patient who is admitted through the E.R. with an initial diagnosis : 37- Which of the following is true about surgical prophylaxis : it is given to treat surgery associated infections 38 -Goals of diabetes mellitus management include : 39 -When dosing insulin which of the following is true : dose may need to be increased during acute illness 40 -What first line agent may be considered fo r an obese type : metformin 41- When diagnosis of diabetes to be considered : oral glucose tolerance test , HBA1c 42 - A 4 mg dose of lorazepam administered to a adult will act as : hypnotic 43- The usual daily dose of phenytoin in the range of : 300-600 mg 44 -The drug of choice to control pain during acute myocardial infarction is : morphine V.15 57.52 g of NaCl exactly 2000 ml.V.Which route of administration would provide the most rapid onset of action response to morphine : I.Category C in FDA for drug used in pregnancy : 47 . injection 49 .Which of the following drugs exhibits dose dependant pharmaceutical therapeutic doses : phenytoin 50 . What is the molarity of this solution : 0.Correct method of parentral administration of potassium is : slow I.45 -What is a major contraindication to the use of an OTC sympathomimetic drug : hypertension 46 .A solution is made by dissolving 17.What advice would you give to a patient prescribed rifampicin : this medication may cause discolouration of urine 48 . 51 -The long term administration of thiazide diuretics requires : K+ 52 -Propranolol is often prescribed with hydralazine to : reduce the reflex tachycardia 53 -Fifty micrograms equals : 50000 ( nanogrames 54 -The ability of a liquid to dissolve is : miscibility 55 .glitazones are ineffective as mono therapy ( True ) .These are non aqueous pharmaceutical solutions : essences 56 . Regarding treatment of digoxin toxicity : check Mg and K levels and correct if needed 65 .life style modification should not be enforced if an oral agent to be startede -lisepro is rapid acting insulin to be dosed immediately before meals (False ) 58 .When a CNS depressant is prescribed .References to check compatibility of drugs in parentral administration : 64 .In CHF management the following is not corr ect : spironolactone should be avoided because of the great risk of hypokalemiad -non drug therapy includes appropriate fluid and dietary sodium restriction 59 .Which of the following is NOT used in theophylline toxicity management : methylphenidate to reduce excessive sedation 62 .We can prepare 100 ml of 12% MgCl by taking : . which of the following is NOT taken at the same time : verapamil 66 .. which is true : betablokers should be avoide d in asthmatic patient 60 .GIT disturbance are common side effects of glycosidase inhibitors (true ) .Regarding the use of ACEIs : most common side effect is chronic dry cough 63 .Which of the following is NOT a primary literature : applied therapeutic & clinical use of drug 61 .start with small dose of ora l agent and triturate up to 1 -2 weeks (True ) .The antimalarial to avoid glucose-6-phosphate dehydrogenase : 67 .When concidering drug therapy for hypertention . which of following is least sedative action : Temazepam 91 .about cardioglycosidic effect : +ve inotropic 78 . c. what is not recommended : electrical cardio 73 -all of following are side effects of methotrixate except : Drive sex gland 74 . 81 .In digoxin induced arrythmia . Molecular weight of drug 80 .factors affect on distribution of drug : Tissue solubility . Protein binding .mechanism of action o f antipsychotic drug : Dopamine receptor inactivation 76 .drug used in hypertension and migrane : Clonidine 75 .trade name of lisinopril : Zestril .B.Which of the following is true about surgical prop hylaxis : it is given to reduce the possibility of surgical site infection 88 .IL blocker 89 . Emollient 82 .promidon . should be treated with : three drugs to ensure eradication of micro-organism .T. b.factors affect on renal clearance : Age .The following is NOT characteristic of solution : the solvent and solute can be separated by filtratione -solute doesn`t precipitate as time passes 69 .ointment used for : Carrier of drug .digoxin differ from digitoxin : Excreted un changed in urine 72.68.all following are viral infections except : Tuberculosis 86 . zinopril 70 .all factors affect on distribution of drug except : Type enzyme respo nse of metabolism 79 .the following are controlled drugs :a. 94 .Which of the following is NOT true about infiximab : 1.in hypodynamic shock treatment : Use dopamine 84 .Which of the following is NOT predinsolone side effect : hypoglycemia 92 – Which one of the following is taken orally : Estrogen gluconate 93 .steroids .infusion of hypotonic solution in blood cause : hemolysis 90 .acyclovir used to : 85 .charcol used as antidote : Adsorption activity 83 .warfarin monitoring : 87 .antipseudomonas drug : vancomycin 71 .diazepam.ACE inhibitors are contraindicated in : bilateral renal artery stenosis 77 . r.p.-3 .The responsibility of pharmacist in hospital is : deal with drug interaction 96 .95 . b. soon .p.stat: immediately .the following abbreviations are correct :a.Duiretic which is more potent than others is : bumetanide 98 .r.: rectally 97 .: if needed .Food poisoning caused by : bacteria 99.n. c . c. 8. 9.i.c. motility d-could be used in pregnant women if need d.c.c.a.c.i.d. b. b.i.The Latin abbreviation for " After Meals " is : a.c. d.Rifampicin is indicated for treatment of : a-impaired fat absorption c-tuberculosis e-psoriasis b-pulmonary emboli d-neoplastic disorders 6.a.c.o. e .a.The major action of sodium chromoglycate is:a-mast cell stabilization c-prostaglandins modifier e-non of the above b-bronchodilator d-leukotrienes modifier 2-The action of histamine is : a-capillary constriction c-stimulation of gastric secretion d-skeletal muscle paralysis b-elevation of blood pressure e-slowing the heart rate 3-One of the following antibiotics is resistant to penicillinase : a-penicillin V c-floxapen e-amoxicillin b-penicillin G d-ampicillin 4.t.Erythroped A : a-is effective against G +ve Cocci b-is a macrolide antibiotic c-can increase g.p.c. b.Inderal is : a-similar in action to ergotamine b-similar in action to tubocurarine c-used as an antihistamine d-pure b -adrenergic receptor blocker 5. e .c.Which of the following is non selective b1 blocker ? a-labitolol c-cloridine e-verapamil b-terazosine d-captopril 7. .c. c. d.q.1.The latin abbreviation for " Every Night " is : a.c.c. e . c. 10.i.p.n. c.The latin abbreviation for " Four Times Daily " is : a.a.c.a.a.p.a.c. Allopurinol is used as : a-analgesic agent b-uricosuric agent c-antiinflamatory agent d-antipyretic agent e -agent which increases renal tubular reabsorptio n Allopurinol inhibits xanthine oxidase. 13.Myocardial muscle tissue property to generate electrical is : a-inotropy b-chronotropy c-automaticity d-contractility e -non of the above " Dromotropic effect" 17.A disease which is due to viral infection : a-poliomyelitis c-chicken pox e -all of the above b-rabies d-herpes 15. Oxypurinol also inhibits xanthine oxidase. and then the side effect of increased tubular reabsorption of calcium. reducing the conversion of hypoxanthine and xanthine to uric acid and resulting in direct inhibition of purine biosynthesis due to elevated oxypurine concentration (negative feedback). decreased renal tubular transport of uric acid.Which of the following is NOT betamethasone side effect ? A-cataract b-hypoglycemia c-skeletal muscle weakness d-sodium retention e-lowered resistance to infections 14.e -all of the above 11. So anyway you have dramatically decreased uric acid concentrations.The heart`s dominant pacemaker is : a.SA node d-internodal pathways .AV node c-pukinje fiber e-non of the above b.The mechanism of action of atropine is : a-muscarinic antagonist c-nicotinic antagonist e-non of the above b-muscarinic agonist d-nicotinic agonist 16.For the treatment of anaphylactic shock use : a-salbutamol c-acetazolamide e-aminophylline b-diphenhydramine d-epinephrine 12. The term shock signifies : a-hyperperfusion d-bradycardia b-hypoperfusion e-non of the above c-tachycardia 24.O2 retention d.CO2 removal e-non of the above b.Adenosine P produces which of the following : a-facial flushing b-dyspnea c-marked tachycardia d.Which of the following is responcible for buffering a-magnesium c-bicarbonates e-troponin b-chloride d-potassium 21. b and c 20.18.O2 removal c. by bacterial cell wall during there growth) a-endotoxin d-cytotoxin b-exotoxin e-non of the above c-antibiotics 26.Respiratory acidosis is due to : a.CO2 retention 22.a and b e.In treatment of shock .Which of the following is released by bacterial infection?(…. which of the following should be considered? a-airway control b-IV of crystalloid solution c-dopamine to support blood pressure d-monitor heart rhythm e -all of the above 25.Adenosine is used for : a-ventricular arrythmias b-atrial bradycardia c-supraventricular tachycardia d-supraventricular bradycardia e-non of the above 19.a .the amount of water in adult male is about: a-25% b-60% c-80% d-10% e -17% .Which of the following is NOT colloid solution ? a-albumin 5% c-dextran e-albumin 20% b-ringer`s solution d-beta starch 23. Decrease oncotic pressure c-capillary permeability d.In the treatment of osteoporosis which of the following is NOT true? a-alendronate should be taken 60 min.Concerning COX 2 inhibitors . which is NOT true? a-they have lower risk gastric adverse reactions b-good evidence about their effectiveness c-cardiac toxicity is a recent concern of this class d-they usually administrated twice daily e -combination with non selective agents give mo re effective action 30. before breakfast b-Ca and vit.Which of the following is NOT a risk factor for osteoparalysis? a-minimal exercise b-low calcium intake c-male gende r d-family history e-minimal exposure to sunlight 33.Early symptoms of aspirin poisoning are : a-lethergy & fatigue b-skin rash & headache c-throbbing headache & dizziness . b and 28.a .Which of the following are causes of oedema? a. D are essential c-hormone replacement therapy should be considered d-outcome should be assessed with periodic bone density e-raloxifeno is selective oestrogen modulator 31.Patients prescribed non reversible monoamine oxidase inhibitor should be advised not to consume food containing tyramine because this combination causes: a-postural hypotension b-hallucinations c-anaphylactic shock d-muscle weakness and tremor e -acute adrenergic crisis including sever hy pertention 29.27.Increase hydrostatic pressure b.a and b e.Which of the following is the first choice in acute gout? a-allopurinol c-colchicine sulfinylpyrazone b-indomethacin d-probencid e- 32. Goals of diabetes mellitus management include : a-reduce onset of complications b-control symptoms of diabetes .When diagnosis of diabetes to be considered : a-WBC count with differential b-oral glucose tolerance test d.The usual daily dose of phenytoin in the range of: a.d-fluid retention hypotension e-ringing in the ears & blurred vision 34.A patient who is admitted through the E.A disease modifying drugs in rheumatoid arthritis: a-gold preparations b-hydroxychloroquine c-methotrexate d.R.considered anticoagulation with warfarine d.a .a and b c.a and b e . with an initial diagnosis : a-slow ventricular response using verapamil b-start lidocaine infusion c.15-60 mg d -should be continued for 7 days after 40.1-5 mg c.b and c 39. b and c 36.Which of the following is NOT true about infiximuab a-IL-1 blocker b-used for treatment of severe rheumatoid arthritis c-may increase risk of infections d-administered as IV infusion e-postadministration reactions include fever & chills 35.300-600 surgery e-all are true b.HBA1c e .a and b e.Which of the following is true about surgical prophylaxis ? a-it is given to treat surgery associated infections b-it is given to reduce the possibility of surgical site infection c-should always be given regardless type of surgery d-should be continued for 7 days after surgery e-all are true 38.b and c 37. b and c 41.a .52 g of NaCl exactly 2000 ml.15 d-3.c-near normal glycemic control and HBA1c d.m and 1/3 p. mouth washes and nasal soln.33 c.a .60 b.3.a and b e .A solution is made by dissolving 17. What is the molarity of this solution? a.00 x 10 -4 e-1.Propranolol is often prescribed with hydralazine to a-reduce the reflex tachycardia b-prevent the accumulation of hydralazine c-prevent systemic lupus ( SLE ) due to hydralazine d-prevent oedema .6x10 -4 44. b and c 42.1. collodions an elixirs c-gargles . .6 u / kg / day split 2/3 a. liniments and spirits 43. d-syrups .b and c e . mucillages and collodions e-enemas .0. douches and irrigation soln.When dosing insulin which of the following is true? a-initial dose 0.What first line agent may be considered for an obese type 2 ? a-glyburinid d-nateglinid b-insulin e-repaglinid c-metformin 41-30gm of 1% hydrocortisone mixed with 40 gm 2.These are non aqueous pharmaceutical solutions: a-otic soln.5% hydrocortisonen what is the concentration of the resulting solution? a) 3% c)10% d) none of the above b) 1. b-essences .Which of the following drugs exhibits dose dependant pharmaceutical therapeutic doses ? a-Na valproate d-quinidine b-phenytoin e-carbamazepine c-lithium 45.m b-regular NPH ratio is 1 : 1 or 1 : 2 c-dose may need to be increased during acute illness d.85% 42. Which of the following is NOT correct ? a-glitazones are ineffective as mono therapy b-GIT disturbance are common side effects of glycosidase inhibitors -a c-start with small dose of oral agent and triturate up to 1-2 weeks d-life style modification should not be enforced if an oral agent to be started e-lisepro is rapid acting insulin to be dosed immediately before meals 48. which of the following is NOT taken at the same time? a-analgesic b-verapamil c-aspirin juice d-diphenhydramine e -orange .References to check compatibility of drugs in parentral administration: a.MERCK Index b-handbook on injectable drugs c-micromedix d.e-increase absorption of hydralazine 46.Which of the following is NOT a primary literature a-gournal of pharmacy practice b-applied therapeutic & clinical use of drug c-new England Journal of medicine d-Loncet e.b and c 51.effect in selected patient c-spironolactone should be avoided because of the great risk of hypokalemia d-non drug therapy includes appropriate fluid and dietary sodium-restriction e-symptomatic improvement is one of the major assessment criteria for proper therapy 49.a and b e.When a CNS depressant is prescribed .JAMA 50.The ability of a liquid to dissolve is : a-hydrophilicity c-immiscibility b-miscibility d-solubility equilibrium 47.In CHF management the following is not correct: a-ACEIs such as lisinopril improves left ventricular function and reduces mortality -blocker such as carvidailol may have beneficialb b. injection .What advice would you give to a patient prescribed rifampicin? a-take this medication with food or milk b-avoid multivitamine preparations during treatment c-avoid taking paracetamol during treatment d-possible discolouration of skin is of no importance e-this medication may cause discolouration of urine 57.52. injection b-slow I.V.The drug of choice to control pain during acute myocardial infarction is : a-naloxone d-celecoxib b-bethidine e-naproxen c-morphine 54.What is a major contraindication to the use of an OTC sympathomimetic drug a-gastric ulcer c-severe asthma e-hypertension b-uncontrolled hypotension d-rheumatoid arthritis 55-Category C in FDA for drug used in pregnancy : a.controlled studies fail to demonstrate a risk to the fetus in the trimester and there is no evidence of risk in later trimester b.Correct method of parentral administration of potassium is : a-fast I.M.V.fetal risk NOT demonstrated in animal studies but there are no controlled studies in pregnant women or animal reproduction studies have shown an adverse effect that was NOT confirmed in controlled studies in women during trimester c-either animal study have revealed adverse effect on the fetus and there are no controlled human studies or studies in animal and women are not available d. injection d-IP(intraperitoneal) injection c-I.A 4 mg dose of lorazepam administered to a adult will act as : a-analgesic d-antihistaminic b-hypnotic e-antiulcerant c-diuretic 53.There is positive evidence of human fetal risk but the benefits of use in pregnant woman may be acceptable despite the risk 56. CO3 b.M.0005 g d.Fifty micrograms equals: a-50000 ( nanogrames )? c. b-S. which is true? a-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-beta-blokers should be avoided in asthmatic patient e. e-rectal c-I.Regarding the use of ACEIs : a-associated hypokalemia could be avoided by giving K-supplement b-effective in reducing proteinurea in diabetic patient c-most common side effect is chronic dry cough d-a good first line treatment for hypertensive diabetic e-dose should be started low and triturated gradually upward in need 64.Regarding treatment of digoxin toxicity: a-verify time of last time b-check Mg and K levels and correct if needed d-no antidote for digoxin c-monitor ECG e-supportive care .V. 59.0.0.The long term administration of thiazide diuretics requires : a.b blocker for tachycardia d-control vomiting with metoclopramide e-methylphenidate to reduce excessive sedation 63.ACEIs are recommended in pregnant women 62.Ca++ 60.K+ d.When concidering drug therapy for hypertention .C.58.acetate c.Na+ e.a and b e.Which of the following is NOT used in theophylline toxicity management : a-symptomatic control of seizures with benzodiazepine b-activated charcoal to enhance elimination c.a and c b.05 ( milligrams )? 61.Which route of administration would provide the most rapid onset of action response to morphine ? a-oral d-I. analgesic effect except a-ibuprofen c.5 ml of MGCL dissolve in 100 ml water e-.The antimalarial to avoid in glucose-6-phosphate dehydrogenase deficiency : a-primaquine c-chloroguanide b-quinine 66-HOW can prepare 100 ml of 12% MgCl by taking ? a-12ml of MGCL dissolve in 100 ml water b-12 mg of MGCL dissolve in 100 ml water c-12ml of MGCL dissolve in 1000 ml water d-90.aspirin d.dopamine agonist c.5HT1 antagonist 70.Serotonin reuptake b. ………….All the following anti inflammatory.sevredol 73.insulin . a.mannitol b.first pass b.Role of B-blockers in angina.When drug absorbed through GIT then go to liver and excreted this process called a. 71.65.dextrose 5% d.drug distribution 72.Suspension e.Role of carbidopa in treatment of Parkinsonism.naprosyn b.Dopamine antagonist e.95 ml of MGCL dissolve in 100 ml water 68-The following is NOT characteristic of solution: a-thermodynamically stable b-composed of two or more component that exist in one phase c-homogenous d-the solvent and solute can be separated by filtration e-solute doesn`t precipitate as time passes 69.emulsion 74-azaleic acid used in c .drug metabolism c.Decrease dopamine in peripheral vessel d.which of the following need filt ration before IV infusion a. .metoformin d-.can increase GIT motility d-can not used in pregnant women if needed e. c .excretion in kidney decrease b.cimetidine c.age d...metabolism is high e...dosage form e .sex c ....a-acne b..A and B 78-monitoring for dose in elderly patient: a.to increase duration of lidocaine in anasethia a.has amino glycoside antibiotic c-decrease GIT motility d-should not be used in pregnant woman if need e-should be used in pregnant woman if need .Atropine e .which of the following are characteristic for Erythrosine: a-not effective aga inst G+ve cocci b..psoriasis c ..which hormone are secreted from posterior pituitary gland a.epinephrine 77....myocardial infarction 75.Drug state b...Drug absorption depend on a..A .decrease in liver enzymes function c.which of the following are characteristic for Erythroped a.........oxytocin b.not macrolide antibiotic c...b 79-which of the following cause metallic taste a..captopril b.none of the above 81..reabsorption is high d.not effective against G +ve cocci b......growth hormone c-adrenocorticosteroid hormone 76.propranolol b.succinyl choline d. 80. .1 November b.. 91-which of the following is antiarrythmic class Ιa:a.which of the following has aldosterone antagonist effect a..Class ΙΙ antiarrythmic drugs produce its action through:- .hemoglobin test d-..serum creatinine level b...spironolactone b.< 10μg 83.amiloride c.hydrochlorothiazide 89-which of the following change color of the urine to red nitrofurantoin .if patient take Gentamicin for a time which of the following need monitoring test a. rifampicin 90.....liver enz..lidocaine c.propranolol d-Quinidine 92....Omeprazole used to: decrease gastric acid secretion.amiodarone b.. 88...furosemide d. 87.31 November 85-The mechanism of action of Buspirone through a-5HT antagonist b-GABA agonist c-dopaminergic agonist d-dopaminergic antagonist 86..82-the optimal size for ophthalmic drops:... 84-if packaged are written for expiry November 2006 it mean that can be used till a.Amphetamine is used in: defect of awareness in the brain of children.. test c.Nitroglycerine introduces: coronary vasodilatation. shorten action potential 93. zinopril or zestril is found in :a-captopril c. 98. 96. 95-lovastatin produce action through:HMG-co reductase inhibitor.ophthalmic prescription are written through following ( gtt tod Bid ) this mean:a. seizures .decrease rate of phase 0 depolarization b.shake well and then give one drop to left eye twice daily d.decrease rate of phase 0 depolarization b.a.Streptokinase is used in ttt of :pulmonary emboli.ramipril b.increase phase 3 repolarization c.lisopril .suppress phase 4 depolarization d.fosinopril d-lisinopri 97. 101-all the following are antifungal except :- .shake well and then give one drop to right eye twice daily.antiarrythmic drug class Ιb produce its action through:a.solubility d-optical activity. b. 100.increase phase 3 repolarization c.adrenergic receptor blocking e.chelating prep.″ om″ is abbreviation for at morning.give one drop to left eye twice daily c.Chiral molecule mean:a-dipole moment c.decrease phase 4 depolarization d. 99-tegretol is used in ttt of:status epileptic .adrenergic receptor blocking 94.give one drop to right eye twice daily b. third generation cephalosporin d. 110.Nystatin b.warfarin monitoring therapy by:a.Which organism are the cause of travel er diarrhea:E-coli.fourth generation cephalosporin 103.progesterone and LH .Ketoconazole d.second generation cephalosporin c.lipid profile 111-in ovulation phase which hormone is predominant :a-FSH c. 106-diazepam used in:anxiety.ciprofloxacin 105.co-trimoxazole d. 107-solid to be reduced in size before dissolving called:disintegration.first generation cephalosporin b. 104.progesterone b-LH d.APTT b.Bambuterol is used in:treatment of asthma. 109-Vinca alkaloids produce anticancer drugs :vincristine . vindesine.amoxicillin c.Drug used in ttt of traveler diarrhea:a-ampicillin b.Gamciclovir.Amphotericin c. 102.a. 108-Benzodiazepine mechanism through:binding δ subunit of GABA -A receptor.platelet count d.INR c. vinblastine .ceftazidime is:a. can't be used as monotherapy in mild HTN:a.hydralazine b.hydralazin 117.moist heat 114-which of the following need serum level monitoring with Quinidine:a-Digoxin b.cholinergic antagonist c.Ecothiophate mechanism through:a-binding to muscarinic receptor b.which of the following has catharitic side effect :a. constipation c.magnesium sulphate c.make complex with anticholinesterase and inhibit its action .hydrochlorothiazide 118.pindolol d. b-ophthalmic prep. 120.propranolol d.albutrol c-ampicillin d-Diazoxide 115.side effect of epinephrine is:a.ischemic damage e.calcium sulphate 119-normal water can be used in:a. 113-most common process for sterilization:a.headache .parentral prep.losartan c .filtration b.aluminum silicate b.oral susp. d-external prep. vomiting b.skin rash 116-drug used for ttt of migraine and HTN:a-clonidine b.nausea .dry heat c.atenolol e.hypoglycemic effect d.112-vencuronium is used as :skeletal muscle relaxant.minoxidil c. c. cholinergic agent d.PPM mean:part per million OR million part 127-all are causes of 2ry HTN except:a.irreversible 124.chemical Rx d.adsorption 125.Bioequivalent c.Digoxin used in ttt of CHF as has:+ VE inotropic effect 126.sod.2k d.0..vitD metabolite c.Charcoal produce its action through:a.phyochromocytoma b. c.………….C c . intake 128-pt CHF take digoxin and hydrochlorothiazide with ray arthritis which of the following drugs can be used :a-cortizone c-fluticazone b-hydrocortisone d-prednisolone 129-if a drug has the same active ingredient like other drug but not contain the same inactive ingredient this mean :a.neuromuscular blocker 122-half life for first order kinetic:a.spinal anesthesia d.pharmaceutical alternative b-pharmaceutical equivalent d.reversible e – B.physical Rx b.693k 123-adsorption are affected by the following except :a.B .A.k b-1/k c .121-tetracaine is used as:a-opoid pain b. conc.nephrotoxicity c.postural hypotension d.130.arrhythmia 139.5 mg________ 5ml x? mg________ 150 ml x mg=7. so.5 mg in teaspoonful what will be conc.albumin 2% d. contin coal tar 30 part petroleum 15 part adeq.albumin 20% c.which of the following not used in ttt of asthma:- .pindolol d-…………. of coal tar in 500ml=30x500/195=76. 134-Alteblase is used:anticoagulant 135. in 150 ml:7.Beta starch e .labetolol b. of coa l tar in 500 ml:30 part present in 195ml of prep.salbutamol is used as:. x part present in 500ml of prep.bronchodilator 136-podocodeine is used in dry cough 137-which of the following not used in emergency HTN:a.5x150/5 =225 mgْْْْْ 131. 138-Doxorubicin side effect :a. of adrug is 7. conc.furosemide c.9 part 132-which of the following is not colloid A-kerbs solution b.prep.Dextran 133-sildenafil is found in Viagra.cardiac toxicity b. to 150 part what conc. Ergot alkaloids is used as antineoplastic 150.400 mg/day c -90mg/day 147.Cyclophosphamide d.slightly soluble C-immisc ible d.Buffering agent used in ophthalmic drops to :decrease irritation to eye and increase stability 151-picosulphate is used as laxative 152.Daily recommended dose for vit.miscible e.non polar d.insoluble 142-benzoil not soluble in H2O but soluble in benzene in 25◦ c a.polar b.hepatic pt .Daily recommended dose for folic acid 400 -500 μg 146.000 part of water a. C in female :a-30mg/day b-50 mg/day d-200 mg/day e.Which of the following is alkylating agent and anticancer a-vinblastine b.one of the following is member of phenothiazines group prochlorperazine 144-primidone is prodrug for ( antiepileptic drug ) .Digoxin toxicity increase with:a. C in male :a-30mg/day b-50 mg/day d-200 mg/day e.fairly soluble b. daily dose for paracetamol is ( 4000 mg ) 149.max.slightly polar c-soluble 143.Very small molecule(1 part ) soluble in 10.cisplatin c.a. 145.renal failure b.Daily recommended do se for vit.vicristine 141.B2 agonist b-B2 antagonist 140.400 mg/day c -90mg/day 148.insoluble e. IV infusion 160.oint.a. solution .drug stored in the body in:a.fat b.nicotine d.G+ve .IM b.in case of hepatic or renal failure which muscle relaxant is recommended :158.C.Hyperglycemia d.oint .G-ve only .action ↑ e. gel. d.Heparin can be monitored through :a.constipatio n 154-which of the following narcotics not used today:a.heroin c.INR 159-Enixoparin is administrated:a. solution c.c. gel e . b.side effect ↑ b.APTT b.All the following are side effect of oral contraceptive except:a-hypertension b-weight gain c.IV c.morphine b.Asthmatic pt 153.dizziness e.protein 156-which of the following dosage form are famous:a. G-ve b.solution.lipid c.solution . gel 157.half life ↓ d.codeine 155.if drug protein binding increased or decreased:a. oint. gel .half life ↑ c.muscle d.b 161-3rd generation cephalosporin has:a.G+ only c.S. oint .connective tissue e. GABA receptor 166.determination analysis of solution depend on a-nature of solute b.ampicillin b.increase surface area c.sustained release dosage form is used to c -propranolol .a.PRAVOC is used as:a.antibiotic 171.decrease surface area e.reduce particle size b.what is drug of choice in ttt of bronchospasm/asthma:a-salbutamol (albutrol ) b-theophylline d-esmolol e.anticoagulant b.convulsion sedation 168.phenytoin act on :.A&B 163.antiplatellet c.quinidine 169. abdominal disturbance d- e.b 164-when use liquid or oint.relaxation to brochial smooth muscle b.reserpine 170.nausea . CO c.NSAIDs produce action through:decrease prostaglandin s ynthesis 167.increase cardiac contractility.which of the following not characteristic of theophylline :a.increase particle size d. to dissolve the solid it is called :levigation 165.162-solubility enhanced through :a.type of solution c-analyzer d.453 kg 172.pound = 0.which of the following cause depression :a. electrical property which produce impulses called : a-conduction c-velocity b-automaticity d.……………………….thiamine e.diltiazim classified as : .twice weekly HOW can taken:- b. Ca channel blocker 178-B carotine is precursop of : a-retinol d.a-increase half life b. 173.drug after metabolized in liver it will become:a-polar b.half life of drug is 7 days a.lipophilic d.non polar c.infusion of hypertonic solution in blood cause : a) shriniking of blood cell b) hemolysis c) hyperglycemia d) hypoglycemia e) b + d .twice daily d.infusion of hypotonic solution in blood cause : a) shriniking of blood cell b) hemolysis c) hyperglycemia d) hypoglycemia e) b + d 181.every day c.drug have low therapeutic index c..insoluble 174.excitability 180.pyridoxine b.calcefirol c-riboflavin 179.every week 177.loading dose definition 175.repolarization to ca out 176.in phase 1 in muscle contract ion occur:a-depolarization for k in b. 185.182..drug induced lupus like syndrom is associated with antihypertinsive ? a-minixidil d-nitroprusside Na b.How gm of substance X must added to 2000 gm of 10% substance X solution in order to prepare 25% of substance x solution ؟ a) 10000 b) 400 c) 40 d) 10 e) 0..5 e) 1500 184..0005 b) 0.dosage form of nitroglycren when used in malignant hypertension ? a-IV d.proteins d-carbohydrate e-.. if 0.major metabolism proccess in GIT is:a-hydrolysis c.4 عوزين نعرف هنضيف%02 جرام بتركيز0222 الحل سهل إن شاء هللا هو عندنا مادة وزنها %02 علشان يوصل التركيز بنسبة%022 أد إيه من المادة دية والذي سوف يكون بتركيز (X) 100% 15 25% (2000gm) 2000gm -------------75 X gm -------------15 So...C 187.oxidation b..hypothirodism cause :a-weight gain c-low body temp b.....How gram needed from drug .5 gm of drug ? a) 0. c.denaturation will happened in body for which compounds? a-penicillin c.1 gm in ml .infusion b-IM e.transdermal c... if 5 one tspfull doses contain 7..acetylation d-conjucation 186.S.acebutol 188...hypoglycemia d-. X gm =15x2000/75 =400 gm 10% 75 183..hydralazine e.lipid b.5 c) 500 d) 1..dioxide .... About definition of first pass effect .suspension 194-abot ophthalmic preparation as single dose which is false:a-sterile c-should cotain preservative b.inhibition of converting angiotensin I to angiotensin II 190.A&B 191.good lipoprotien.5: 9 B+C 90% 80% 50% 197.true solutions another name is:a..increase pka d.3: 1 b-1:3 c-10:30 d.transport fatty acid 193.ACE I mechanism of action as antihypertension ??? .low density lipoprotein(LDL) act as : a-carrier cholesterol in plasma c. 195-most of drugs are : a-Weak electrolyte b-Non electrlolyte c-Non ionic d-Strong electrolyte e-B+ C 196-90% of substance X solution .heterogenous d. b. it increase with:a. 50% of substance X solution .metal used in rheumatoid arthiritis : gold 192.189. how mixing both to give 80% of substance X solution ? a.purified d-……….increase rate of absorption b.antipseudomonas drug : a-metronidazole c.primaquine b-nystatin d-vancomycin 198-digoxin differ from digitoxin : a-Half life b-Excreted hepatically 30 10 .increase biotransformation c.homogenous c-emultion b. mechanism of action of antipsychotic drug : Dopamine receptor inactivation 205.ACE inhibitors are contraindicated in : bilateral renal artery stenosi 206.hormone excreted from adrenal cortex : a-Growth hormone b-Primary product c-mineral corticoids (eg. what is not recommonded? a-stop digixin administration b-phenytoin administration c-give lidocaine d-give digoxin immune fab e-electrical cardio 200.which is not asthma properties : a-Bronchodilator b-Bronchospasm c-Increase mucous secretion d-Chest pain 201.In digoxin induced arrythmia . cortisolndrosterone) e-weak androgens (eg.all of following are side effects of methotrixate except : a-Bone marrow depression b-Alopecia c-Nausea and vomiting e-Drive sex gland 204. dehydroepiandrosterone) 202. aldosterone) d-glucocorticoids (eg.d-Excreted unchanged in urine 199.about cardioglycosidic effect : a--ve inotropic b-+ve inotropic c-Hypertension d-Tachycardia e-Bradycardia 207-all factors affect on distribution of drug except a-Tissue solubility b-Protein binding : .immunosuppressant agent cannot used in organ transplantation : Predisolone 203. which is not true a.in hypodynamic shock treatment we used :a.nicotine c.ointment used for : a-Carrier of drug b-Emollient c-A&B d-Increase absorption e-Increase distribution 210.c-Molecular weight of drug d-Type enzyme response of metabolism 208-all factors affect on renal clearance except : a-Age b-Sex c-Both d-Disease state 209.which drug has spasmolytic action? a-Resirpine b-Amphetamine 215-desmopressine used in :nocturnal enuresis 216.lady take chronic warfarin .which of following is least sedative action ? a-Diazepam b-Estazolam c-Triazolam d-Temazepam 214. monitor INR to avoid DVT e-take care about nasal bleeding 213.dopamine b.avoid aspirin containing prepration b-avoid doubling dose from herself c-balanced food with green leaves to avoid thrombosis d-if she pregnant.aspirin 211-acyclovir used to : Herbs simplex 212.pentophyllin used for : a-peripheral vasodilator . including ischemic stroke and resultant conditions.b-Hypertension c-Cough suppressant Indications Pentofyllin is indicated in diseases.000002 ppm 218. causing disorders in the peripheral perfusion. diabetic angiopathy.C 222. In acute disorders of the brain perfusion.about nor epinephrine not true :a-increaser B. Raynaud’s disease. according ppm : a-2 ppm b-0. gangrene. atherosclerotic and inflammatory disorders.PHARMACOKINETIC CONSTANT :a-Zero order b-1st order c-2nd order d-Mixed order e-A + B 223. including shank ulcers. IM 221. Acute disorders of the retinal blood supply.Which of the following is NOT predinsolone side effect ? . intermittent claudication.002 ppm c-0. 217-2 mg \ L solution . which is not true ? a-Has gram –ve activity b-Less toxicity c-Narrow therapeutic d-Compatible with other drug e-Usually IV . and in diabetes.normal water used for : a-Eye preparption b-Parentral preparation c-Solution d-Emultion e-External preparation 219.P b-vasoconstrictive c-used in cardiogenic shock d-effective orally e-S.ceftazidime : 3rd generation 220-about amino glycoside . infused for 12 hours .ACEIs are recommended in pregnant women 225-solutions are better than solid dosage form coz: a-Accurate dose b-Easy to handle c-More stable d-Faster action e-B + C 226. which is true? a-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-b-blokers should be avoided in asthmatic patient e.When concidering drug therapy for hypertention . for 70kg patient.One of following NOT used to cover bitter taste:a-Film coat b-Enteric coat c-Grinding of tablet 227-which of following tricyclic antidepressant is tertiary amine? Amitriptyline 228.antihypertensive used in pregnancy ? Alpha Methyldopa 229-drug used for peptic ulcer ?( Losec) 230.a-cataract b-hypoglycemia c-skeletal muscle weakness d-sodium retention e-lowered resistance to infections 224.drug infusion rate is 2mg\kg\hr . what is total dose? (2x70x12)=1680 mg 231-( GMP) mean:a-Good Manufactor Protocol b-Good Manu factor Product c-General Manufactor Protocol . chemical stability b.anion exchange 239-The conc.Light sensitive drug should be storage in:- .add another to increase it is activity c.block Ca to intracellular & increase metabolism from storage site 236.according to steril method which of the following is false about filtteration: عليك أن تختارable to filtter viscous substance 234.a+c 235.All of this affect rate of absorption except:a.when you know the preservative used with anti biotic is not suitable you make:a.d-General Manufactor Product 232-how many gm of water add to 5% KCL soln to make 180 gm of solution(w\w)? 5gm--------------100 Xgm--------------180 X= 5x180/100=9 gm So.PH c-protein binding d. Of ionized & unionized calculated by (Henderson hasselbachk equation) 240.use tow or more preservative may increase the activity and may become suitable d.9 =171 gm 233. the amount of water is:180 .deltiazem & nifedipine &flocdipine act as .B&C 237-Doxorubicin side effect is tissue necrosis .A&B e.use another one is suitable b. 238-Cholystyramin resin act by :. gamma rays.The most common reaction catalysed by cytochrome P450 is a monooxygenase 246-The most common phase I reaction is oxidation 247-Which Of The Following NOT Used In Peptic Ulcer :a-Tetracycline c-Metronidazole e-clarithromycin b.a-Colorless glass glass b-Colorless plastic c-Amber d-Amber plastic e-Light resistant container 241-Electromagnetic rays :. 244-Coal tar uses in (psoriasis).pyrogen free c.lidocaine d.Isotonic e. color change in skin. x-rays.hydralzyine . Chloride d-free from bacteria 250. stomach discomfort or pain. 242-Cyclophosphamide (side effects) Appetite loss. absence of menstrual periods. diarrhea.hydrazyline c-propranolol e. 243-Isoproterenol( Isoprenaline ) adrenergic agonist medication. texture change in nails. hair loss. 245.A&C b-free from sod.Itraconazole d-bismuth subsalicylate 248-Which Of The Following act as alpha 1 blocker :a. general unwell feeling. weakness. nausea.clonidine b-terazocine d-captopril 249-comparison between sterile water &water for injection:a. skin rash.Qunidine has similar action to :a-procainamide c-propranolol b. vomiting. 2mg b-2mg c-200mg d-2000mg .penicillin V 256.Cephalosporin act as:a-Inhibitors b-inhibitors c-Inhibitors d-Inhibitors e-Inhibitors of cell membrane function nucleic acid synthesis of protein synthesis of cell wall synthesis of metabolism 255.lidocaine c.Ampicilline has similar action of:a.Amoxicillin b.Antipseudomonal Antibiotic :(piperacillin.Antibiotic used as anti pseudomonas aeruginosa:a.ticarcillin ) 257-Auxliar of label are written on box contain COTRIMETHOXAZOLE all is true except:a-shake the bottle before use b-suspension c-freezing of drug d-keep out of reach of children 258-Ipratropium bromide :-(Anti muscarinic bronchodilator ) 259-keep in cool place means :a-in refrigerator b-in freezing c-at 10-20 c* d-A&C e-A&B 260-5mlof injection that conc.Which of the following drug has side effect lupus like syndrome : a.tetracycline c-cloramphinicol b-cephalexin d-amikacine 254.251.Meropenem c.Over dose of digoxine we use:-(anti dote FAB Fragment ).Bacitracin d.carbencillin. 0. 253.4% calculate the amount of drug? a-0.procainamide b-minoxdile d-hydrochlorothiazide 252. >oint d-any dosage form can be used 270-digoxin toxicity precipitated by :. > solu.e-20mg 261-How need prepare benzacainamid conc. Proffered to be taken:a-solu. 267-which of the drug used in open angel glaucoma:(pilocarpine ) 268-All (ACEIs) are prodrug except:.(inhibited blood clot ) 265-cyclophosphamide side effect is:a-blared vision. > susp.30cc of benzocainamid solution? a-30 d-100 b-50 e-130 c-80 262-Amphetamine act as :(INDIRECT-ACTING ADRENERGIC AGONIST) 263-Increase plasma HDL Level :(Reduce Risk of Atherosclerosis ) 264-Waraferin act as:. > oint. c-susp. 1:1000.(Hypokalemia ) 271-which of the following drug has anti inflammatory effect :(Ibuprofen ) .alopecia c-bone marrow depression d-A&B e-B&C 266-Action of alpha 1 receptor:-………………….CAPTOPRIL (prototype) 269-Opthalmic prep. b-solu. > oint > susp.…………… b-vomiting . 5mg/ml dissolve in 30ml water calculate the amount of KI in the solu. shaped b-shorten P. ? (15mg) 278-Omeprazol used for :. To :AUC (Area Under the Carve ) 275-Cephalaexine is :-first generation cephalosporin. 282-mechanism of action of Buspirone on:Serotonin (5HT2a) receptor 283-All these cases not cure with thiazides except:a-hypernatrimia c-Hypokalaemia e-Hyponatrimia b-Hyperglycemia d-Hyeruriceamia .T.R 273-Digitoxine toxicity effect in electro cardio chart (ECG):a-prolong P.R d-prolong B.R d-prolong B.peptic ulcer 279-Alph 2 Agonist :Decrease blood pressure 280-The equation that determine the acid & base degree is:(BRONESTED EQUATION ) 281-ISONIAZIDE used in TIBERCULOSIS .T.R c.272-Digitoxine effect in electro cardio chart (ECG):a-prolong P. Has 0.R c. 276-After the myocardial infraction we use :Anti platelet (aspirin) 277-KI solu. shaped b-shorten P. drug &test drug acc.R 274-Relative bioequivalent compared between std. 286. 296-Anti psychotic act as :.000 IU for the correction of the deficiency &for therapy from 100.Laxative 289-POM mean:. 285-Vit.000-50.PSORIASIS 294-which of the following make water retention:(Indomethazine) 295-Nitroglycerin is :.(Vasodilatation of coronary artery).All these cases not cure with thiazides except:a-hypercalcemia c-Hypokalaemia e-Hyponatrimia b-Hypoglycemia d-Hyeruriceamia 287-Zidovudine is used for HIV.000-200. A daily dose is 30. Of the drug on exp. Lauryl Sulphate 292-The drug transfer through the cell membrane by :a-Aqueous diffusion c-Lipid dissolve e-NON of the above b-Osmotic pressure d-Passive diffusion 293. Date is :From 90-110% 291-Surfactant not used orally :Sod.(Dopaminergic Antagonist ) . 288-Bisacodyl used as :.Calcipotriol is indicated for :.284-Which of the following drug of choice for Myxodema:(Hypothyroidism ) :-Thyroxin sod.prescription only medicine 290-The con.000 IU/day. the sp.Which Of The Following act as alpha 1 blocker :( PRAZOCIN). 301-Whate The Specific gravity of substance has Weight=Y & The volume is X ? The Specific gravity =Density of the substance/Density of water So.HEPARINE 299-Prmethazine used as :Anti histaminic (pruritus . the sp. gravity of sub.Vit. =Y/X 302-ESMOLO is:Short acting B.blocker used in emergency in Acute arrhythmia as IV administration . =weight (Y) /volume(X)/1 So.WARAFARINE 298-protamine sulphate is anti dote of:. مع تمنياتي لكم بالتوفيق والنجاح مصطفى محمد الشلق/ أخوكم شركة تداوي السعودية .297. K is antagonist of :.anti emetic) 300. gravity of sub. cough . latabbreviation for " After Meals " is c.Which of the following is responcible for buffering c-bicarbonates***** 5-. which of the following should not be considered? a-airway control b-IV of crystalloid solution c-dopamine to support blood pressure d-monitor heart rhythm e-give antibiotic to treat infection***** 6-.Myocardial muscle tissue property to generate electrical is c-automaticity**** 4.1-The action of histamine is : c-stimulation of gastric secretion ***** 2.p.c. *** 3-.In treatment of shock .In the treatment of osteoporosis which of the following is . before breakfast**** b-Ca and vit.When concidering drug therapy for hypertention .hypothirodism will increase : a) body weight **** 15. with an initial c- considered anticoagulation with warfarine**** 8 -The usual daily dose of phenytoin in the range of: d.A patient who is admitted through the E. which is best choice? . D are essential c-hormone replacement therapy should be considered d-outcome should be assessed with periodic bone density e-raloxifeno is selective oestrogen modulator 7.R.B carotine is precursor of : a)retinol **** 11-antihypertensive produce tackycardia : a)Hydralazone***** 12-process require CYP405 : a)OXIDATION 13-drug induced lupus like syndrom is associated with b) phenytoin *** 14.NOT true? a-alendronate should be taken 60 min.300-600 mg**** 9. which is true? d-blokers should be avoided in asthmatic patient **** 10.low density lipoprotien act as : a) Major carrer of cholestrol in plasma ***** 16-patient has CHF given digoxin and thiazide and needed corticosteroid . expairy date of drug is 8\2010 that means .which is not asthma properties : a) Bronchodilator***** b) Bronchospasm c) Increase mucous secretion d) Chest pain 22-.about side effect of quinidine : Chichonism******* 25-all of following are side effects of methotrixate except: . last day you can use drug is : a) 31\8\2010….digitoxin side effect : a) Hyperglycemia b) Hypertension 19.hormone excreted from adrenal cortex : a) Aldosterone ****** b) Growth hormone c) FSH 23.elevated blood glucose is side effect of : Digoxin…………..a) Cortisone b) Hydrocortisoce c) Prednisolone 17.one of following is not alpha 1 agonist : a) Clonidine b) Alpha methyl noradrenaline****** c) Guanfacine d) Guanabenz e) Guanethidine 24. 20-amphetamine used to treat : a) Defect concentration ***** 21-..***** 18. which is not true? .Adsorption . which is not true : a) Chemical property b) Physical property c) Reversible d) Irreversible e) A + d **** 28-all are antibiotic except : Famcyclovir ***** 29.about norepinephrine .about digitoxin .heparin monitoring : T c) APTT**** 30. which is false : a) Oral bioavaiability 100% b) Protein binding 95% c) Half life is 7 days d) Mainly hepatic metabolism by lysosmal …… 31-all r Beta 2 agonist except : a) Salbutamol b) Alburanol c) Fenoterol d) salmeterol e) Pindolol ***** 32-Pkw for normal water in room temperature : b) 14**** 33.a) Bone marrow depression b) Alopecia c) Nausea and vomiting d) Stimulate sex drive **** e) Alopecia وكتب معها كمان شي 26.ACE inhibitors are contraindicated in : bilateral renal artery stenosis***** 27. .. which is false? a) Cannot used for virus ***** ... what drug added to increase effectiveness of lidocaine? Epinephrine ………….all contraindicated in pregnancy except b) Methyldopa**** 37.o. 41-about sterilization by filtration .one of following not used to cover bitter taste : a) Enteric coat b) Film coat c) Enteric coat d) Grinding of tablet **** e) B + C 36.m.dose of drug in children is ……. mg ف تحويل الوحدات ضروري 38-drug prescriped as 1 tablet contaion 1 mg bid ( 2 weeks) . what is total dose? 28 mg***** 39. Mg \ kg .tybe 2 anti arrythmic properties : Inhibit sympathetic system by beta adrenergic blockade *** 40-in injection of lidocaine .5 bound? اختيارات بالوحدتين وكان كاتب gm ...P b) vasoconstrictive c) used in cardiogenic shock d) effective orally'***** e) S.a) increasr B.C 34-. what total dose for child 34. every morning****** 35.. 44)in prescription Substance A 15 parts Substance B 30 parts Substance C 150 parts We neeed to prepare ointment 500 gm . what amount should we take from substance A ? قلت انا حليتها.we need to prepare 100 ml of 0..loop diuretics cause all the following except: a) Hypokalamia.46 gm 38. e) Hypernatremia... (15 \195) * 100 =7. c) Hypocalcemia.22 micropores . d) Hypoglycemia..69 * 500 ) \ 100 = 38.بطريقة نسبة وتناسب....46 gm**** وانا كانت عالمتي بالمسائل كاملة يعني.**** .69 % So .69 % from all 500 gm ( 7.b) Need special equipment 42-membrane filters with 0.05 gm*** 46. مسائل وهو أحد االختيارات الموجودة5 الحمدهلل حليتهم صح 45.صح 15+30 + 150 = 195 المادة االولى من كل الوصفة اذا بدي اعرف كم نسبة..05% substance X solution…… how gm we need from substance X ? 0.. we need 7. b) Hyponatrimia. which of following not removed by that? a) Bacteria b) Virus*** c) Fungi d) A+c e) B+c 43)volatile substance given by inhalation: a) Halothane b) Dextromethorphane…………. *** 51) The antidote of heparin is: Protamin sulfate**** 52)when gived gentamycin . c) Normal saline. called: a) Pharmaceutical equivalences b) Bioequivalence c) A + b d) Pharmaceutical alternative 48-to compare between 2 drugs use: a) Physical appearance b) Weight c) Pharmacokinetic parameters d) Pharmacodynamic parameter*********** e) Taste 49) Cardiac arrest could be managed by the following except: a) Ephedrine. which is should monitoring? Creatinine clearance**** 53-tricyclic antidepressant mechanism of action : 54-diazoxide side effect : hypotension 55-tegretol used in : Trigeminal Neuralgia**** 56-about sid effect of oral contraceptive except : a) Depressoin b) Hypertension 57-drug dependence which is true : . d) Propranolol**** 50)-Binding to plasma protein: a. b) Lidocine.47-two drugs has same active ingredient but difrent inactive ingredient .Increases half life. a_terazosin: is a selective alpha 1 antagonist 6_syncop may occure with the 1st dose of the folowing a_digoxin b_salbutamol . patient has withdrawal symptoms b) Patient progressively increase dose to get same action االختيارات كانت مستبعدة تماما بقيت 58)drug used in ventricular arrhythmia : a) Phynetoin ****** b) Quinidine c) Digoxin d) Procainamide e) Verapamil 59)Enteric coated tablets: Are dissolved in the intestine and not affected by the stomach juices***** 60) factors affecting on dissolution rate are : b) Decrease size of particles c) Increase surface area e) B + C****** 1-(propranolol)whicl is adrenergic beta blocker 2_propranolol is beta blocker 3_salbutamol is selctive b2 agonist 4_which is false about nor epinephrin a_ effictive orally b_can used in cardiogenic shock c_can used subcutanous d_raise blood pressure 5_which is the folowing block the alpha receptor in vains and arteries and amke v.a) After discontinuation .d. ... 12_which one is more effective agaienst traveller diarrhea b_ciprofloxacin c_sulphamethoxasol 13_which is the following is true about erythromycin b_could be used in pregnant women if need 14_which one is active against psoudomonal d_imipinem _15_A 4 mg dose of lorazepam administered to a adult will act as : b-hypnotic 16_ the action of TCa is inhibit reuptak of noradrenalin and serotini 17_Which of the following drugs exhibits dose dependant pharmaceutical therapeutic doses ? b-phenytoin ......c_prazosin : alpha blocker d_reserpin e_ clonidin 7_one of the fllowing used in asthmatic patient answer is albuterol 8_the pharmacolpgical action of clofibrate is c_decreas lipoprotien synthes 9_one of the following has cathertic effect b_magnesium oxide 10_loratidin is c_antihistaminic 11_which of the following not anti bacterial .. 18_The long term administration of thiazide diuretics requires a.arization of phase 0 b_delay the repolarization of phase 3 answer is b 26_which one is antiarrythmic class 1A d_verapamil 27_which one doesnt affect platellet in the body a _ aspirin b_dipyridamol c_acetyl salcylic d_captopril e_clopidogril 28_action of theophyllin b_ bronchodilator .K+ 19_antihypertensive produce tackycardia : a)Hydralazone 20_ the pharmacological action of nitroglycerin is 21_the action of digoxin can reduced with a_ antacid 22_ the main cause of digitalis toxicity is d_renal faliure 23_digitalis arrhythmia can be treated with a_lidocain 24_which one used in ventricular arrhthmia with heart block phynetoin 25_the action of antiarrhythmic drug classs 1A is a_rapid the repo. What is the molarity of this solution answer molarity= number of moles/volume in liter number of moles=weightin gram/molecular weight .52 g of nacl exactly 2000 ml... 33_one of the following not NSAID a_ naprocyn b_indocid c_ticotil d_اعتقد مش فاكر اسمه بس هوا ده كان االختيار 34_pentoxifillin used as 35 _ which one used to trigeminal neuralgia answer is tegretol وممكن برده الphynetoin الفارما دي كانت اسئله المسائل مسائل5 كان في 1_ how many doses in abottle contain 90 gram and the dose is 75mg answer number of dose = 90/0.75=120 2_A solution is made by dissolving 17......29_anti cancer derived from venca is_ a_cyclophosamide b_flourouracil c_doxurubcin d_ cicplastin i think d 30_ alkylating agent used as anticancer d_cyclophosphamide 31_ascorpic acid is b_ vit C 32_reserpin shouldnt be used in parkinsonism patient talking... 5/58.09 c_.125 L b_0.3 molarity = 0..W.250 L c_0.0009 e_.of NaCL=MW ob Na(23.15 3_the solution contain 9ppm of NaCl the the concevtration of the compound in the solution a_0.9 b_.4 L d_2 L e_ 4 L انا كتبتها0. 4_ how much amount of water need to add to 250 ml of solution os 1/500 of benzonium clorid to bacome 1/2000 a_0.5=0 .4 ومعرفش صح وال غلط المساله الخامسه مش فاكرها افتكر الباقي واكتبه وان شاء هللا بالنسبه لceutics and clinical االسئله هحاول افتكر واكتب 1_the statement (put in cold place ) mean acoording to USP a_ in the freezer b_in refrigerator c_ temp between(10_20 c)f d_ a&c e_ b&c انا كتبتهاc بس متهيالي انهاe 2_all factors affect on distribution of drug except : a_Tissue solubility b_Protein binding c_Molecular weight of drug ...00009 انا.0حلتها بس مش عارف صح وال غلط.5 then number of mole= 17.M.3/2=0.5+MW of Cl (35=58.009 d_. b_ acetylation c_oxidation d_ conjucation answer a 5_the amount of water in adult male is about: b-60% 6_process require CYP450 : a)OXIDATION b)HYDROLYSIS c)GLUCORONIDATION d)DEAMINATION e)SULFERATION انا كتبتها بس معرفش صح وال غلطoxidation 7_Adsorption . which is not true : a) Chemical property b) Physical property c) Reversible d) Irreversible e) A + d answer is e 8_acording to 1st order kinetics t1/2 equal a_k b_1/k c_k+1 d_2k+1 e_ 639/k .d_Type enzyme response of metabolism answer is d 3_ONE OF FOLLOWING NOT USED TO COVER BITTER TASTE : a_Film coat b_Enteric coat c_Granding of tablet answer is c 4_major metabolism proccess in GIT is a_hydrolysis . answer is e 9_the responce of the drug not affected by a_mental status b_genetic c_binding to plasma ptn d_lipophilicity of the drug انا كنت محتار بين االولي والتانيه بس اخترت االولي 10_جالي مش عارف حله بس هقوله في سؤال للعاملين في الصيدليه ويوجد بها تعليمات معني السؤال (الورقه اللي صاحب الصيدليه بيكتبها الصديليه ) دي اسمها ايه مديني اختيارات غريبه وطبعا كان 11_ الصيدليه علي الرف برده سؤال تاني عن كيفيه ترتيب مستحضرات العيون في المعلق ثم المراهم ثم المحلول) ( يعني مثال نرتب كاالتي (المحلول ثم المراهم ثم المعلق )او وهكذا 12_ الفرق في الفاعليه نفس السؤال اللي فات بس عن طريق 13_about steady state concentration during IV adminestration a_directly ptoportional to volume of distribution b_inversly proportional to volume of distribution c_directly ptoportional to infusion rate d_ inversly proportional to total body clearance e_ c&d answer is e 14_disentegration of drug to small molecule is a_ reduction b_ sublimation c_ solubility فاكر باقي االختيارات بس انا حلتها مشa the way for 1st pass metabolism_15 كان في اختيارات بس االجابهfrom mesentric vain to portal vain . Inderal is: a-similar in action to ergotamine b-similar in action to tubocurarine c-used as an antihistamine d-pure β-adrenergic receptor blocker e.α and β-adrenergic receptor blocker .The major action of sodium chromoglycate is a-mast cell stabilization b-bronchodilator 2 c-prostaglandins modifier d-leukotrienes modifier e-non of the above 2-The action of histamine is: a-capillary constriction b-elevation of blood pressure c-stimulation of gastric secretion d-skeletal muscle paralysis e-slowing the heart rate 3-One of the following antibiotics is resistant to penicillinase: a-penicillin V b-penicillin G c-floxapen (flucloxacillin) d-ampicillin e-amoxicillin 4.16_ which of the following decreas gastric emptying rate a_ metoclopramid b_ atropin c_ hypothyroism d_a&b e_b&c answer is e ــــــــــــــــــــــــــــــــــــــ ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ 1. omni nocte c.Rifampicin is indicated for treatment of: a-impaired fat absorption b-pulmonary emboli c-tuberculosis d-neoplastic disorders e-psoriasis 6.n.c.The Latin abbreviation for "Four Times Daily" is: a. cubic centimeter= 1ml 8.c.a. e.q.c.c 10.i.The Latin abbreviation for "Every Night" is: a.The Latin abbreviation for "After Meals" is: a. d.p. c.a. b.c d.c.i.d quater in die e.Erythroped A: a-is effective against G +ve Cocci and G –ve bacteria b-is a macrolide antibiotic .a.Which of the following is selective β1-blocker? a-labetalol α & β-blocker b-terazosine selective α1-blocker c-cloridine selective α2-agonist d-captopril ACE inhibitor e-verapamil calcium channel blocker None of them is a selective β1-blocker 7.p.c.c.a.5.c.o.c. for each c.a. 9.c d.a.c e.a.c. b.i.p.c. before meals b. Allopurinol is used as: x a-analgesic agent x b-uricosuric agent (as probenecid).The heart's dominant pacemaker is: . as in the pacemaker cells of the heart) d-contractility e-none of the above 17.The mechanism of action of atropine is a-muscarinic antagonist b-muscarinic agonist c-nicotinic antagonist d-nicotinic agonist e-none of the above 16.For the treatment of anaphylactic shock use: a-salbutamol b-diphenhydramine c-acetazolamide d-epinephrine e-aminophylline ? 12. x c-anti-inflammatory agent x d-antipyretic agent ? e-agent which increases renal tubular reabsorption 13.Myocardial muscle tissue property to generate electrical is: a-inotropy (=contractility = the force of muscle contraction) b-chronotropy (= affecting a time or rate.c-can increase g.t.i.A disease which is due to viral infection: a-poliomyelitis b-rabies c-chicken pox d-herpes e-all of the above 15. motility d-could be used in pregnant women if need e-all of the above 11.Which of the following is NOT betamethasone side effect? a-cataract b-hypoglycemia c-skeletal muscle weakness d-sodium retention e-lowered resistance to infections 14. as in heart rate) c-automaticity (= a property of specialized excitable tissue that allows self-activation through spontaneous development of an action potential. The term shock signifies: a-hyperperfusion b-hypoperfusion c-tachycardia d-bradycardia e-non of the above .a.CO2 retention e-none of the above 22.O2 retention c.Which of the following is responsible for buffering a-magnesium b-chloride c-bicarbonate d-potassium e-troponin 21.a and b e.AV node b.Adenosine P produces which of the following: a-facial flushing b-dyspnea c-marked tachycardia d.Adenosine is used for: a-ventricular arrhythmias b-atrial bradycardia c-supraventricular tachycardia d-supraventricular bradycardia e-none of the above 19.SA node c-purkinje fiber d-internodal pathways e-non of the above 18.CO2 removal d.Respiratory acidosis is due to: a.Which of the following is NOT colloid solution? a-albumin 5% b-ringer's solution c-dextran d-beta starch e-albumin 20% 23.a . b and c 20.O2 removal b. Concerning COX 2 inhibitors.by bacterial cell wall during their growth a-endotoxin b-exotoxin c-antibiotics d-cytotoxin e-none of the above 26.Which of the following are causes of oedema? a-increase hydrostatic pressure b-decrease oncotic pressure c-increase capillary permeability d. before .The amount of water in adult male is about: a-25% b-60% c-80% d-10% e-17% 27.a and b e. b and c 28..24.In the treatment of osteoporosis which of the following is NOT true? a-alendronate should be taken 60 min.a. which is NOT true? a-they have lower risk of gastric adverse reactions b-good evidence about their effectiveness c-cardiac toxicity is a recent concern of this class d-they usually administrated twice daily e-combination with non selective agents give more effective action 30. which of the following should be considered? a-airway control b-IV of crystalloid solution c-dopamine to support blood pressure d-monitor heart rhythm e-all of the above 25which of the following is released by bacterial infection? (.Patients prescribed non reversible monoamine oxidase inhibitor should be advised not to consume food containing tyramine because this combination causes: a-postural hypotension b-hallucinations c-anaphylactic shock d-muscle weakness and tremor e-acute adrenergic crisis including sever hypertension 29..In treatment of shock. A disease modifying drugs in rheumatoid arthritis: a-gold preparations b-hydroxychloroquine c-methotrexate d.lethargy & fatigue b.breakfast b-Ca and vit. D are essential c-hormone replacement therapy should be considered d-outcome should be assessed with periodic bone density e-raloxifeo is a selective oestrogen receptor modulator 31.a and b e.used for treatment of severe rheumatoid arthritis c.Early symptoms of aspirin poisoning are: a. with an initial diagnosis: a-slow ventricular response using verapamil b-start lidocaine infusion .ringing in the ears & blurred vision 34.fluid retention hypotension e.may increase risk of infections d.Which of the following is the first choice in acute gout? a-allopurinol b-indomethacin c-colchicine d-probencid e-sulfinylpyrazone 32.Which of the following is NOT true about infiximab a.a.IL-1 blocker b.minimal exposure to sunlight 33. b and c 36.family history e.low calcium intake c.A patient who is admitted through the E.post administration reactions include fever & chills 35.Which of the following is NOT a risk factor for osteoparalysis? a.administered as IV infusion e.minimal exercise b.R.throbbing headache & dizziness d.skin rash & headache c.male gender d. Which of the following is true about surgical prophylaxis? a.b and c 42.a and b e.6 u / kg / day split 2/3 a.A 4 mg dose of lorazepam administered to an adult will act as: a-analgesic b-hypnotic .HBA1c d.a and b e. b and c 40. b and c 39.m b-regular NPH ratio is 1 : 1 or 1 : 2 c-dose may need to be increased during acute illness d.When diagnosis of diabetes to be considered: a-WBC count with differential b-oral glucose tolerance test c.a.it is given to treat surgery associated infections b-it is given to reduce the possibility of surgical site infection c-should always be given regardless type of surgery d-should be continued for 7 days after surgery e-all are true 38.b and c e.When dosing insulin which of the following is true? a-initial dose 0.m and 1/3 p.considered anticoagulation with warfarine d.a.c.What first line agent may be considered for an obese type 2? a-glyburinid b-insulin c-metformin d-nateglinid e-repaglinid 41.Goals of diabetes mellitus management include: a-reduce onset of complications b-control symptoms of diabetes c-near normal glycemic control and HBA1c d.a and b e.b and c ?? 37. What advice would you give to a patient prescribed rifampicin? a-take this medication with food or milk b-avoid multivitamin preparations during treatment .1-5 mg c.c-diuretic d-antihistaminic e-antiulcerant 43.15-60 mg d.The drug of choice to control pain during acute myocardial infarction is: a-naloxone b-bethidine c-morphine d-celecoxib e-naproxen 45.The usual daily dose of phenytoin in the range of: a.300-600 g b.controlled studies fail to demonstrate a risk to the fetus in the trimester and there is no evidence of risk in later trimester b.What is a major contraindication to the use of an OTC sympathomimetic drug a-gastric ulcer b-uncontrolled hypotension c-severe asthma d-rheumatoid arthritis e-hypertension 46-Category C in FDA for drug used in pregnancy: a.There is positive evidence of human fetal risk but the benefits of use in pregnant woman may be acceptable despite the risk 47.300-600 mg e.fetal risk NOT demonstrated in animal studies but there are no controlled studies in pregnant women or animal reproduction studies have shown an adverse effect that was NOT confirmed in controlled studies in women during trimester c-either animal study have revealed adverse effect on the fetus and there are no controlled human studies or studies in animal and women are not available d.1-2 mg 44. V.c-avoid taking paracetamol during treatment d-possible discolouration of skin is of no importance e-this medication may cause discolouration of urine 48.V. injection c-I.K+ b.Correct method of parentral administration of potassium is: a-fast I.Ca++ d.0.acetate 52.Which of the following drugs exhibits dose dependant pharmaceutical therapeutic doses? a-Na valproate b-phenytoin c-lithium d-quinidine e-carbamazepine 50. e-rectal 51. c-I.V.Na+ c.CO3 e.M.a and b .0. d-I.Fifty micrograms equals: a-50000 ( nanogrames )h g b.The long term administration of thiazide diuretics requires: a. injection b-slow I.0005 g d.C.Propranolol is often prescribed with hydralazine to a-reduce the reflex tachycardia b-prevent the accumulation of hydralazine c-prevent systemic lupus ( SLE ) due to hydralazine d-prevent oedema e-increase absorption of hydralazin 53.Which route of administration would provide the most rapid onset of action response to morphine? a-oral b-S.05 ( micrograms )m g c.M. injection d-IP(intraperitoneal) injection 49. 15 c.00 x 10-4 Molarity = no.a and c 54.e.3 moles M = 0.5) = 0. of moles = weight (gm) / molecular weight = 17.The ability of a liquid to dissolveis: a-hydrophilicity b-miscibility c-immiscibility d-solubility equilibrium e-solvation energy 55. mucillages and collodions e-enemas .1.52 g of NaCl in exactly 2000 ml.A solution is made by dissolving 17.52 / (23+35. b-essences. .60 x 10-4 d. What is the molarity of this solution? a. collodions and elixirs c-gargles.33 b.3/ 2 = 0.0.30 e-3.Which of the following is NOT correct? a-glitazones are ineffective as mono therapy b-GIT disturbance are common side effects of a-glycosidase inhibitors c-start with small dose of oral agent and triturate up to 1-2 weeks d-life style modification should not be enforced if an . d-syrups .0. of moles/ volume (Liter) No.These are non aqueous pharmaceutical solutions: a-otic soln. mouth washes and nasal soln.3. douches and irrigation soln. liniments and spirits 56.15 57. Which of the following is NOT a primary literature a-journal of pharmacy practice b-applied therapeutic & clinical use of drugs c-new England Journal of medicine d-Loncet e. which is true? a-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-beta-blokers should be avoided in asthmatic patient e.Regarding the use of ACEIs: a-associated hypokalemia could be avoided by giving K-supplement b-effective in reducing proteinurea in diabetic patient . -blockers such as Carvedilol may have beneficial effect in selected patients c-spironolactone should be avoided because of the great risk of hypokalemia d. -blocker for tachycardia d-control vomiting with metoclopramide e-methylphenidate to reduce excessive sedation 62.non drug therapy includes appropriate fluid and dietary sodiumrestriction e-symptomatic improvement is one of the major assessment criteria for proper therapy 59.Which of the following is NOT used in theophylline toxicity management: a-symptomatic control of seizures with benzodiazepine b-activated charcoal to enhance elimination c.In CHFmanagement the following is not correct: a-ACEIs such as lisinopril improve left ventricular function and reduces mortality b.ACEIs are recommended in pregnant women 60. encyclopedias 61.JAMA Primary literature: journal articles Secondary literature: textbooks Tertiary literature: reference books: dictionaries.When considering drug therapy for hypertension.oral agent to be started e-lispro is a rapid acting insulin to be dosed immediately before meals 58. which of the following is NOT taken at the same time? a-analgesic b-verapamil c-aspirin d-diphenhydramine e-orange juice 68-The following is NOT characteristic of solution: a-thermodynamically stable b-composed of two or more components that exist in one phase c-homogenous d-the solvent and solute can be separated by filtration e-solute doesn't precipitate as time passes most of drugs are : Weak electrolyte* Non electrlolyte Non ionic .c-most common side effect is chronic dry cough d-a good first line treatment for hypertensive diabetic e-dose should be started low and triturated gradually upward in need 63.Regarding treatment of digoxin toxicity: a-verify time of last time b-check Mg and K levels and correct if needed c-monitor ECG d-no antidote for digoxin e-supportive care 65.References to check compatibility of drugs in parentral administration: a.b and c 64.When a CNS depressant is prescribed.a and b e.MERCK Index b-handbook on injectable drugs c-micro comedix d. .. 50% of substance X solution . …………increase in o2 demand dialitation in myocardium 6-digoxin differ from digitoxin : Half life Excreted hepatically . how mixing both to give 80% of substance X solution ? 3: 1 ** 1:3 10:30 5: 9 B+C 3-trade name of lisinopril …… Zestril .Strong electrolyte B+ C 2-90% of substance X solution ... nystatin .. 5. **vancomycin ... primaquine....antipseudomonas drug : metronidazole .arrhythmia happened due to : increase of Cardiac output .. zinopril 4. aldosterone) glucocorticoids (eg. cortisolndrosterone) weak androgens (eg.which is not asthma properties : Bronchodilator Bronchospasm Increase mucous secretion Chest pain 9. 10.example of antimetabolite anticancer ….immunosuppressant agent cannot used in organ transplantation : . phenytoin adminstration give lidocaine give digoxin immune fab electrical cardio*****…… 8. dehydroepiandrosterone) 11.hormone excreted from adrenal cortex : Aldosterone Growth hormone ……… Primary product mineralocorticoids (eg.Excreted unchanged in urine *** 7. what is not recommonded?? stop digixin adminstration ..In digoxin induced arrythmia . .mechanism of action of antipsychotic drug : Dopamine receptor inactivation 17-drug used in hypertension and migrane : Clonidine**** Hydralazine……… 18. 13..liquid weight = ……. volume = ……. What is specific gravity ? 14.Predisolone 12.about side effect of quinidine 15..which is not NSAID ……….all of following are side effects of methotrixate except : Bone marrow depression Alopecia Nausea and vomiting *****Drive sex gland 16. .ACE inhibitors are contraindicated in : bilateral renal artery stenosis . about cardioglycosidic effect : -ve inotropic +ve inotropic **** Hypertension Tackycardia Bradycardia 20-all factors affect on distribution of drug except : Tissue solubility Protein binding Molecular weight of drug Type enzyme response of metabolism ***** 21-all factors affect on renal clearance except : Age Sex**** Both Disease state 22.ointment used for : Carrier of drug Emollient ***Both .19. all following are viral infections except : Tuberculosis 27.warfarin monitoring: Platelet formation INR The prothrombin time (PT) is the primary assay used in monitoring warfarin 29.in hypodynamic shock treatment : Use dopamine ***** Use nicotine Use aspirin 25-acyclovir used to : Herbs simplex 26.Increase absorption Increase distribution 23-charcol used as antidote coz : Adsorption activity 24.about radiation 28.lady take chronic warfarin . which is not true . .Which of the following is true about surgical prophylaxis ? a-it is given to treat surgery associated infections ****b-it is given to reduce the possibility of surgical site infection c-should always be given regardless type of surgery d-should be continued for 7 days after surgery e-all are true 31. مرات4 . مرات. monitor INR to avoid DVT****** 5-take care about nasal bleeding 30.half life of drug is 7 days . 3 مرتين في اليوم. مرة اسبوعيا يعطى مره اسبوعيا .avoid aspirin containing prepration 2-avoid doubling dose from herself 3-balanced food with green leaves to avoid thrombosis 4-if she pregnant. كل يوم.infusion of hypotonic solution in blood cause : a) shriniking of blood cell b) hemolysis**** c) hyperglycemia d) hypoglycemia e) b + d ? كل كم يوم تعطي الجرعة للمريض33...Which of the following is NOT true about infiximab a-IL-1 blocker**** b-used for treatment of severe rheumatoid arthritis c-may increase risk of infections d-administered as IV infusion8 e-postadministration reactions include fever & chills 32..1.. including ischemic stroke and .pentophyllin used for : peripheral vasodilator Hypertension Couph suppressantIndications Pentofyllin is indicated in diseases. In acute disorders of the brain perfusion. atherosclerotic and inflammatory disorders. including shank ulcers. gangrene. Raynaud’s disease.a-hyperperfusion ****b-hypoperfusion c-tachycardia d-bradycardia e-non of the above 35. and in diabetes.which drug has spasmolytic action? Resirpine Amphetamine 37-desmopressine used in …… nocturnal enuresis 38-salbutamol is : Beta 2 agonist 39.which of following is least sedative action ? Diazepam Estazolam Triazolam Temazepam *** 36. diabetic angiopathy. intermittent claudication. causing disorders in the peripheral perfusion. Acute disorders of the retinal blood supply.resultant conditions.002 0.normal water used for : Eye preparption Parentral preparation Solution Emultion External preparation 43. according ppm : 2 0.Pka for normal water in room temperature : 7 14 10^7 10^-14 10^14 42.ceftazidime : 3rd generation .000002 41. 40-2 mg \ L solution . 44-about aminoglycoside , which is not true ? Has gram –ve activity Less toxicity Narrow therapeutic Compatable with other drug Usually IV , IM 45- about norepinephrine not true increasr B.P vasoconstrictive used in cardiogenic shock effective orally' S.C 46- PHARMACOKINETIC CONSTANT : Zero order 1st order 2nd order Mixed order A+B 47- Which of the following is NOT predinsolone side effect ? a-cataract b-hypoglycemia**** c-skeletal muscle weakness d-sodium retention e-lowered resistance to infections 48-- The latabbreviation for " After Meals " is : a- a.c. b- a.a. c- p.c. d- i.c. e- c.c. 49-- The latabbreviation for " before meal : a- a.c. b- a.a. c- p.c. d- i.c. e- c.c. 50 - o.d....... Once a day 51- A solution is made by dissolving 17.52 g of kcl exactly 2000 ml. What is the molarity of this solution? 52- When concidering drug therapy for hypertention , which is true? a-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-b-blokers should be avoided in asthmatic patient ****** e- ACEIs are recommended in pregnant women 53- The mechanism of action of dopamine muscarinic antagonist muscarinic agonist***** nicotinic antagonist nicotinic agonist non of the above 54- The heart`s dominant pacemaker is : a- AV nod b- SA node*** c-pukinje fiber d-internodal pathways e-non of the above 55- about albuterol side effect ……… 56- dosage form of nitroglycren when used in malignant hypertension ??? IV , IM , S.C , infusion , transdermal ****........ 57-solutions are better than solid dosage form coz: Accurate dose Easy to handle Morestable ****Faster action B+C 58- ONE OF FOLLOWING NOT USED TO COVER BITTER TASTE : Film coat Enteric coat Granding of tablet ***** 59-ABOUT CARDIAC GLYCOSIDE …….. 60-which of following tricyclic antidepressant is tertiary amine? Amitriptyline 61- antihypertensive used in pregnancy ? Methyldopa latabbreviation for " After Meals " is c. which of the following should not be considered? a-airway control b-IV of crystalloid solution c-dopamine to support blood pressure d-monitor heart rhythm e-give antibiotic to treat infection***** . 65.Which of the following is responcible for buffering c-bicarbonates***** 5-..drug make urine red other than rifampicin ? 63-drug used for peptic ulcer ? Losec 64.all are ACEI except ……. what is total dose 34. *** 3-.The term shock signifies 1-The action of histamine is : c-stimulation of gastric secretion ***** 2.62.c. infused for 12 hours .drug infusion rate is 2mg\kg\hr . for 70kg patient ….In treatment of shock .Myocardial muscle tissue property to generate electrical is c-automaticity**** 4.p. which is true? d-blokers should be avoided in asthmatic patient **** 10.B carotine is precursor of : a)retinol **** 11-antihypertensive produce tackycardia : a)Hydralazone***** 12-process require CYP405 : a)OXIDATION 13-drug induced lupus like syndrom is associated with b) phenytoin *** 14.300-600 mg**** 9.hypothirodism will increase : a) body weight **** 15.R.6-.When concidering drug therapy for hypertention . with an initial c- considered anticoagulation with warfarine**** 8 -The usual daily dose of phenytoin in the range of: d.A patient who is admitted through the E. D are essential c-hormone replacement therapy should be considered d-outcome should be assessed with periodic bone density e-raloxifeno is selective oestrogen modulator 7.low density lipoprotien act as : a) Major carrer of cholestrol in plasma ***** .In the treatment of osteoporosis which of the following is NOT true? a-alendronate should be taken 60 min. before breakfast**** b-Ca and vit. which is not asthma properties : a) Bronchodilator***** b) Bronchospasm c) Increase mucous secretion d) Chest pain 22-.about side effect of quinidine : Chichonism******* .elevated blood glucose is side effect of : Digoxin………….16-patient has CHF given digoxin and thiazide and needed corticosteroid . 20-amphetamine used to treat : a) Defect concentration ***** 21-.expairy date of drug is 8\2010 that means .digitoxin side effect : a) Hyperglycemia b) Hypertension 19.one of following is not alpha 1 agonist : a) Clonidine b) Alpha methyl noradrenaline****** c) Guanfacine d) Guanabenz e) Guanethidine 24.. which is best choice? a) Cortisone b) Hydrocortisoce c) Prednisolone 17.. last day you can use drug is : a) 31\8\2010….***** 18.hormone excreted from adrenal cortex : a) Aldosterone ****** b) Growth hormone c) FSH 23. Adsorption .ACE inhibitors are contraindicated in : bilateral renal artery stenosis***** 27. which is not true : a) Chemical property b) Physical property c) Reversible d) Irreversible e) A + d **** 28-all are antibiotic except : Famcyclovir ***** 29.25-all of following are side effects of methotrixate except: a) Bone marrow depression b) Alopecia c) Nausea and vomiting d) Stimulate sex drive **** e) Alopecia وكتب معها كمان شي 26.about digitoxin .heparin monitoring : T c) APTT**** 30. which is false : a) Oral bioavaiability 100% b) Protein binding 95% c) Half life is 7 days d) Mainly hepatic metabolism by lysosmal …… 31-all r Beta 2 agonist except : a) Salbutamol b) Alburanol c) Fenoterol d) salmeterol e) Pindolol ***** 32-Pkw for normal water in room temperature : b) 14**** . one of following not used to cover bitter taste : a) Enteric coat b) Film coat c) Enteric coat d) Grinding of tablet **** e) B + C 36.dose of drug in children is …….. every morning****** 35.C 34-.P b) vasoconstrictive c) used in cardiogenic shock d) effective orally'***** e) S..about norepinephrine .o.33..m. what is total dose? 28 mg***** 39. what total dose for child 34.all contraindicated in pregnancy except b) Methyldopa**** 37. what drug added to increase effectiveness of lidocaine? Epinephrine …………..5 bound? اختيارات بالوحدتين وكان كاتب gm . mg ف تحويل الوحدات ضروري 38-drug prescriped as 1 tablet contaion 1 mg bid ( 2 weeks) .tybe 2 anti arrythmic properties : Inhibit sympathetic system by beta adrenergic blockade *** 40-in injection of lidocaine ... which is not true? a) increasr B. . Mg \ kg .. 46 gm**** وانا كانت عالمتي بالمسائل كاملة يعني.69 * 500 ) \ 100 = 38.. what amount should we take from substance A ? قلت انا حليتها...صح 15+30 + 150 = 195 المادة االولى من كل الوصفة اذا بدي اعرف كم نسبة.. .22 micropores .. 44)in prescription Substance A 15 parts Substance B 30 parts Substance C 150 parts We neeed to prepare ointment 500 gm . مسائل وهو أحد االختيارات الموجودة5 الحمدهلل حليتهم صح 45..41-about sterilization by filtration . (15 \195) * 100 =7.بطريقة نسبة وتناسب. c) Hypocalcemia.loop diuretics cause all the following except: a) Hypokalamia.46 gm 38.69 % from all 500 gm ( 7.69 % So .05 gm*** 46.we need to prepare 100 ml of 0.05% substance X solution…… how gm we need from substance X ? 0... d) Hypoglycemia. which of following not removed by that? a) Bacteria b) Virus*** c) Fungi d) A+c e) B+c 43)volatile substance given by inhalation: a) Halothane b) Dextromethorphane…………. which is false? a) Cannot used for virus ***** b) Need special equipment 42-membrane filters with 0.. b) Hyponatrimia. we need 7. **** 47-two drugs has same active ingredient but difrent inactive ingredient . which is should monitoring? Creatinine clearance**** 53-tricyclic antidepressant mechanism of action : 54-diazoxide side effect : hypotension 55-tegretol used in : Trigeminal Neuralgia**** 56-about sid effect of oral contraceptive except : a) Depressoin b) Hypertension . b) Lidocine.*** 51) The antidote of heparin is: Protamin sulfate**** 52)when gived gentamycin . c) Normal saline.Increases half life.e) Hypernatremia. called: a) Pharmaceutical equivalences b) Bioequivalence c) A + b d) Pharmaceutical alternative 48-to compare between 2 drugs use: a) Physical appearance b) Weight c) Pharmacokinetic parameters d) Pharmacodynamic parameter*********** e) Taste 49) Cardiac arrest could be managed by the following except: a) Ephedrine. d) Propranolol**** 50)-Binding to plasma protein: a. d.57-drug dependence which is true : a) After discontinuation . patient has withdrawal symptoms b) Patient progressively increase dose to get same action االختيارات كانت مستبعدة تماما بقيت 58)drug used in ventricular arrhythmia : a) Phynetoin ****** b) Quinidine c) Digoxin d) Procainamide e) Verapamil 59)Enteric coated tablets: Are dissolved in the intestine and not affected by the stomach juices***** 60) factors affecting on dissolution rate are : b) Decrease size of particles c) Increase surface area e) B + C****** 1-(propranolol)whicl is adrenergic beta blocker 2_propranolol is beta blocker 3_salbutamol is selctive b2 agonist 4_which is false about nor epinephrin a_ effictive orally b_can used in cardiogenic shock c_can used subcutanous d_raise blood pressure 5_which is the folowing block the alpha receptor in vains and arteries and amke v. a_terazosin: is a selective alpha 1 antagonist 6_syncop may occure with the 1st dose of the folowing . ... 12_which one is more effective agaienst traveller diarrhea b_ciprofloxacin c_sulphamethoxasol 13_which is the following is true about erythromycin b_could be used in pregnant women if need 14_which one is active against psoudomonal d_imipinem _15_A 4 mg dose of lorazepam administered to a adult will act as : b-hypnotic 16_ the action of TCa is inhibit reuptak of noradrenalin and serotini 17_Which of the following drugs exhibits dose dependant pharmaceutical therapeutic doses ? .....a_digoxin b_salbutamol c_prazosin : alpha blocker d_reserpin e_ clonidin 7_one of the fllowing used in asthmatic patient answer is albuterol 8_the pharmacolpgical action of clofibrate is c_decreas lipoprotien synthes 9_one of the following has cathertic effect b_magnesium oxide 10_loratidin is c_antihistaminic 11_which of the following not anti bacterial ... K+ 19_antihypertensive produce tackycardia : a)Hydralazone 20_ the pharmacological action of nitroglycerin is 21_the action of digoxin can reduced with a_ antacid 22_ the main cause of digitalis toxicity is d_renal faliure 23_digitalis arrhythmia can be treated with a_lidocain 24_which one used in ventricular arrhthmia with heart block phynetoin 25_the action of antiarrhythmic drug classs 1A is a_rapid the repo.arization of phase 0 b_delay the repolarization of phase 3 answer is b 26_which one is antiarrythmic class 1A d_verapamil 27_which one doesnt affect platellet in the body a _ aspirin b_dipyridamol c_acetyl salcylic d_captopril e_clopidogril 28_action of theophyllin .b-phenytoin 18_The long term administration of thiazide diuretics requires a. .... 33_one of the following not NSAID a_ naprocyn b_indocid c_ticotil d_اعتقد مش فاكر اسمه بس هوا ده كان االختيار 34_pentoxifillin used as 35 _ which one used to trigeminal neuralgia answer is tegretol وممكن برده الphynetoin الفارما دي كانت اسئله المسائل مسائل5 كان في 1_ how many doses in abottle contain 90 gram and the dose is 75mg answer number of dose = 90/0.52 g of nacl exactly 2000 ml...75=120 2_A solution is made by dissolving 17.b_ bronchodilator 29_anti cancer derived from venca is_ a_cyclophosamide b_flourouracil c_doxurubcin d_ cicplastin i think d 30_ alkylating agent used as anticancer d_cyclophosphamide 31_ascorpic acid is b_ vit C 32_reserpin shouldnt be used in parkinsonism patient talking.. What is the molarity of this solution answer ... 15 3_the solution contain 9ppm of NaCl the the concevtration of the compound in the solution a_0.W. 4_ how much amount of water need to add to 250 ml of solution os 1/500 of benzonium clorid to bacome 1/2000 a_0.5/58.9 b_.molarity= number of moles/volume in liter number of moles=weightin gram/molecular weight M..3/2=0.09 c_.5 then number of mole= 17..0حلتها بس مش عارف صح وال غلط.3 molarity = 0..4 ومعرفش صح وال غلط المساله الخامسه مش فاكرها افتكر الباقي واكتبه وان شاء هللا بالنسبه لceutics and clinical االسئله هحاول افتكر واكتب 1_the statement (put in cold place ) mean acoording to USP a_ in the freezer b_in refrigerator c_ temp between(10_20 c)f d_ a&c e_ b&c انا كتبتهاc بس متهيالي انهاe 2_all factors affect on distribution of drug except : a_Tissue solubility .009 d_.of NaCL=MW ob Na(23.5=0 .5+MW of Cl (35=58.4 L d_2 L e_ 4 L انا كتبتها0.125 L b_0.250 L c_0.0009 e_.00009 انا. b_Protein binding c_Molecular weight of drug d_Type enzyme response of metabolism answer is d 3_ONE OF FOLLOWING NOT USED TO COVER BITTER TASTE : a_Film coat b_Enteric coat c_Granding of tablet answer is c 4_major metabolism proccess in GIT is a_hydrolysis .b_ acetylation c_oxidation d_ conjucation answer a 5_the amount of water in adult male is about: b-60% 6_process require CYP450 : a)OXIDATION b)HYDROLYSIS c)GLUCORONIDATION d)DEAMINATION e)SULFERATION انا كتبتها بس معرفش صح وال غلطoxidation 7_Adsorption . which is not true : a) Chemical property b) Physical property c) Reversible d) Irreversible e) A + d answer is e 8_acording to 1st order kinetics t1/2 equal a_k b_1/k c_k+1 . d_2k+1 e_ 639/k answer is e 9_the responce of the drug not affected by a_mental status b_genetic c_binding to plasma ptn d_lipophilicity of the drug انا كنت محتار بين االولي والتانيه بس اخترت االولي 10_جالي مش عارف حله بس هقوله في سؤال للعاملين في الصيدليه ويوجد بها تعليمات معني السؤال (الورقه اللي صاحب الصيدليه بيكتبها الصديليه ) دي اسمها ايه مديني اختيارات غريبه وطبعا كان 11_ الصيدليه علي الرف برده سؤال تاني عن كيفيه ترتيب مستحضرات العيون في المعلق ثم المراهم ثم المحلول) ( يعني مثال نرتب كاالتي (المحلول ثم المراهم ثم المعلق )او وهكذا 12_ الفرق في الفاعليه نفس السؤال اللي فات بس عن طريق 13_about steady state concentration during IV adminestration a_directly ptoportional to volume of distribution b_inversly proportional to volume of distribution c_directly ptoportional to infusion rate d_ inversly proportional to total body clearance e_ c&d answer is e 14_disentegration of drug to small molecule is a_ reduction b_ sublimation c_ solubility فاكر باقي االختيارات بس انا حلتها مشa the way for 1st pass metabolism_15 . كان في اختيارات بس االجابهfrom mesentric vain to portal vain 16_ which of the following decreas gastric emptying rate a_ metoclopramid b_ atropin c_ hypothyroism d_a&b e_b&c answer is e ــــــــــــــــــــــــــــــــــــــ ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ 1.Inderal is: a-similar in action to ergotamine b-similar in action to tubocurarine c-used as an antihistamine d-pure β-adrenergic receptor blocker e.The major action of sodium chromoglycate is a-mast cell stabilization b-bronchodilator 2 c-prostaglandins modifier d-leukotrienes modifier e-non of the above 2-The action of histamine is: a-capillary constriction b-elevation of blood pressure c-stimulation of gastric secretion d-skeletal muscle paralysis e-slowing the heart rate 3-One of the following antibiotics is resistant to penicillinase: a-penicillin V b-penicillin G c-floxapen (flucloxacillin) d-ampicillin e-amoxicillin 4.α and β-adrenergic receptor blocker . c. b.a.a.c. b.Which of the following is selective β1-blocker? a-labetalol α & β-blocker b-terazosine selective α1-blocker c-cloridine selective α2-agonist d-captopril ACE inhibitor e-verapamil calcium channel blocker None of them is a selective β1-blocker 7. omni nocte c.c d. for each c.n.c.c d.Rifampicin is indicated for treatment of: a-impaired fat absorption b-pulmonary emboli c-tuberculosis d-neoplastic disorders e-psoriasis 6.p.Erythroped A: .c.q.c.c.p.The Latin abbreviation for "Four Times Daily" is: a.i.i. before meals b.a. d.5.p.a.c.c e.The Latin abbreviation for "Every Night" is: a.c.c. e.d quater in die e.a.i.a. cubic centimeter= 1ml 8.The Latin abbreviation for "After Meals" is: a.c.o.a.c. 9.c 10. The mechanism of action of atropine is a-muscarinic antagonist b-muscarinic agonist c-nicotinic antagonist d-nicotinic agonist e-none of the above 16.a-is effective against G +ve Cocci and G –ve bacteria b-is a macrolide antibiotic c-can increase g. x c-anti-inflammatory agent x d-antipyretic agent ? e-agent which increases renal tubular reabsorption 13.Allopurinol is used as: x a-analgesic agent x b-uricosuric agent (as probenecid). motility d-could be used in pregnant women if need e-all of the above 11.t.For the treatment of anaphylactic shock use: a-salbutamol b-diphenhydramine c-acetazolamide d-epinephrine e-aminophylline ? 12.A disease which is due to viral infection: a-poliomyelitis b-rabies c-chicken pox d-herpes e-all of the above 15.i.Myocardial muscle tissue property to generate electrical is: a-inotropy (=contractility = the force of muscle contraction) b-chronotropy (= affecting a time or rate. as in the pacemaker cells of the heart) d-contractility e-none of the above .Which of the following is NOT betamethasone side effect? a-cataract b-hypoglycemia c-skeletal muscle weakness d-sodium retention e-lowered resistance to infections 14. as in heart rate) c-automaticity (= a property of specialized excitable tissue that allows self-activation through spontaneous development of an action potential. 17- The heart's dominant pacemaker is: a- AV node b- SA node c-purkinje fiber d-internodal pathways e-non of the above 18- Adenosine is used for: a-ventricular arrhythmias b-atrial bradycardia c-supraventricular tachycardia d-supraventricular bradycardia e-none of the above 19- Adenosine P produces which of the following: a-facial flushing b-dyspnea c-marked tachycardia d- a and b e- a , b and c 20- Which of the following is responsible for buffering a-magnesium b-chloride c-bicarbonate d-potassium e-troponin 21- Respiratory acidosis is due to: a- O2 removal b- O2 retention c- CO2 removal d- CO2 retention e-none of the above 22- Which of the following is NOT colloid solution? a-albumin 5% b-ringer's solution c-dextran d-beta starch e-albumin 20% 23- The term shock signifies: a-hyperperfusion b-hypoperfusion c-tachycardia d-bradycardia e-non of the above 24- In treatment of shock, which of the following should be considered? a-airway control b-IV of crystalloid solution c-dopamine to support blood pressure d-monitor heart rhythm e-all of the above 25which of the following is released by bacterial infection? (...by bacterial cell wall during their growth a-endotoxin b-exotoxin c-antibiotics d-cytotoxin e-none of the above 26- The amount of water in adult male is about: a-25% b-60% c-80% d-10% e-17% 27- Which of the following are causes of oedema? a-increase hydrostatic pressure b-decrease oncotic pressure c-increase capillary permeability d- a and b e- a, b and c 28- Patients prescribed non reversible monoamine oxidase inhibitor should be advised not to consume food containing tyramine because this combination causes: a-postural hypotension b-hallucinations c-anaphylactic shock d-muscle weakness and tremor e-acute adrenergic crisis including sever hypertension 29- Concerning COX 2 inhibitors, which is NOT true? a-they have lower risk of gastric adverse reactions b-good evidence about their effectiveness c-cardiac toxicity is a recent concern of this class d-they usually administrated twice daily e-combination with non selective agents give more effective action 30- In the treatment of osteoporosis which of the following is NOT true? a-alendronate should be taken 60 min. before breakfast b-Ca and vit. D are essential c-hormone replacement therapy should be considered d-outcome should be assessed with periodic bone density e-raloxifeo is a selective oestrogen receptor modulator 31- Which of the following is the first choice in acute gout? a-allopurinol b-indomethacin c-colchicine d-probencid e-sulfinylpyrazone 32- Which of the following is NOT a risk factor for osteoparalysis? a- minimal exercise b- low calcium intake c- male gender d- family history e- minimal exposure to sunlight 33- Early symptoms of aspirin poisoning are: a- lethargy & fatigue b- skin rash & headache c- throbbing headache & dizziness d- fluid retention hypotension e- ringing in the ears & blurred vision 34- Which of the following is NOT true about infiximab a- IL-1 blocker b- used for treatment of severe rheumatoid arthritis c- may increase risk of infections d- administered as IV infusion e- post administration reactions include fever & chills 35- A disease modifying drugs in rheumatoid arthritis: a-gold preparations b-hydroxychloroquine c-methotrexate d- a and b e- a, b and c 36- A patient who is admitted through the E.R. with an initial diagnosis: a-slow ventricular response using verapamil a and b e.it is given to treat surgery associated infections b-it is given to reduce the possibility of surgical site infection c-should always be given regardless type of surgery d-should be continued for 7 days after surgery e-all are true 38.m b-regular NPH ratio is 1 : 1 or 1 : 2 c-dose may need to be increased during acute illness d. b and c 40.a and b e.b-start lidocaine infusion c.6 u / kg / day split 2/3 a.Which of the following is true about surgical prophylaxis? a. b and c 39.a.b and c ?? 37.Goals of diabetes mellitus management include: a-reduce onset of complications b-control symptoms of diabetes c-near normal glycemic control and HBA1c d.m and 1/3 p.HBA1c d.When diagnosis of diabetes to be considered: a-WBC count with differential b-oral glucose tolerance test c.a and b e.b and c e.What first line agent may be considered for an obese type 2? a-glyburinid b-insulin c-metformin d-nateglinid e-repaglinid 41.b and c 42.considered anticoagulation with warfarine d.A 4 mg dose of lorazepam administered to an adult will act as: a-analgesic .a.When dosing insulin which of the following is true? a-initial dose 0. 1-5 mg c.15-60 mg d.300-600 g b.b-hypnotic c-diuretic d-antihistaminic e-antiulcerant 43.What advice would you give to a patient prescribed rifampicin? a-take this medication with food or milk .The drug of choice to control pain during acute myocardial infarction is: a-naloxone b-bethidine c-morphine d-celecoxib e-naproxen 45.controlled studies fail to demonstrate a risk to the fetus in the trimester and there is no evidence of risk in later trimester b.1-2 mg 44.fetal risk NOT demonstrated in animal studies but there are no controlled studies in pregnant women or animal reproduction studies have shown an adverse effect that was NOT confirmed in controlled studies in women during trimester c-either animal study have revealed adverse effect on the fetus and there are no controlled human studies or studies in animal and women are not available d.300-600 mg e.The usual daily dose of phenytoin in the range of: a.There is positive evidence of human fetal risk but the benefits of use in pregnant woman may be acceptable despite the risk 47.What is a major contraindication to the use of an OTC sympathomimetic drug a-gastric ulcer b-uncontrolled hypotension c-severe asthma d-rheumatoid arthritis e-hypertension 46-Category C in FDA for drug used in pregnancy: a. b-avoid multivitamin preparations during treatment c-avoid taking paracetamol during treatment d-possible discolouration of skin is of no importance e-this medication may cause discolouration of urine 48.0.0005 g . e-rectal 51.M.Propranolol is often prescribed with hydralazine to a-reduce the reflex tachycardia b-prevent the accumulation of hydralazine c-prevent systemic lupus ( SLE ) due to hydralazine d-prevent oedema e-increase absorption of hydralazin 53.0.K+ b.M.CO3 e.Which route of administration would provide the most rapid onset of action response to morphine? a-oral b-S. injection b-slow I. injection d-IP(intraperitoneal) injection 49.V.Which of the following drugs exhibits dose dependant pharmaceutical therapeutic doses? a-Na valproate b-phenytoin c-lithium d-quinidine e-carbamazepine 50.The long term administration of thiazide diuretics requires: a. injection c-I.Fifty micrograms equals: a-50000 ( nanogrames )h g b.C.05 ( micrograms )m g c. d-I.Correct method of parentral administration of potassium is: a-fast I.V.Ca++ d. c-I.acetate 52.V.Na+ c. 33 b.3. collodions and elixirs c-gargles. b-essences. mucillages and collodions e-enemas .5) = 0. mouth washes and nasal soln.15 c. .3 moles M = 0.30 e-3.Which of the following is NOT correct? a-glitazones are ineffective as mono therapy b-GIT disturbance are common side effects of a-glycosidase inhibitors c-start with small dose of oral agent and triturate up to 1-2 weeks d-life style modification should not be enforced if an .00 x 10-4 Molarity = no.These are non aqueous pharmaceutical solutions: a-otic soln.3/ 2 = 0.a and c 54.1.The ability of a liquid to dissolveis: a-hydrophilicity b-miscibility c-immiscibility d-solubility equilibrium e-solvation energy 55.d. d-syrups . liniments and spirits 56. douches and irrigation soln.a and b e.15 57.A solution is made by dissolving 17. of moles/ volume (Liter) No.0.60 x 10-4 d.52 g of NaCl in exactly 2000 ml. of moles = weight (gm) / molecular weight = 17. What is the molarity of this solution? a.0.52 / (23+35. Which of the following is NOT used in theophylline toxicity management: a-symptomatic control of seizures with benzodiazepine b-activated charcoal to enhance elimination c.non drug therapy includes appropriate fluid and dietary sodiumrestriction e-symptomatic improvement is one of the major assessment criteria for proper therapy 59.oral agent to be started e-lispro is a rapid acting insulin to be dosed immediately before meals 58.Regarding the use of ACEIs: a-associated hypokalemia could be avoided by giving K-supplement b-effective in reducing proteinurea in diabetic patient . which is true? a-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-beta-blokers should be avoided in asthmatic patient e. -blockers such as Carvedilol may have beneficial effect in selected patients c-spironolactone should be avoided because of the great risk of hypokalemia d.In CHFmanagement the following is not correct: a-ACEIs such as lisinopril improve left ventricular function and reduces mortality b.ACEIs are recommended in pregnant women 60. -blocker for tachycardia d-control vomiting with metoclopramide e-methylphenidate to reduce excessive sedation 62.Which of the following is NOT a primary literature a-journal of pharmacy practice b-applied therapeutic & clinical use of drugs c-new England Journal of medicine d-Loncet e.JAMA Primary literature: journal articles Secondary literature: textbooks Tertiary literature: reference books: dictionaries. encyclopedias 61.When considering drug therapy for hypertension. which of the following is NOT taken at the same time? a-analgesic b-verapamil c-aspirin d-diphenhydramine e-orange juice 68-The following is NOT characteristic of solution: a-thermodynamically stable b-composed of two or more components that exist in one phase c-homogenous d-the solvent and solute can be separated by filtration e-solute doesn't precipitate as time passes most of drugs are : Weak electrolyte* Non electrlolyte Non ionic .Regarding treatment of digoxin toxicity: a-verify time of last time b-check Mg and K levels and correct if needed c-monitor ECG d-no antidote for digoxin e-supportive care 65.When a CNS depressant is prescribed.MERCK Index b-handbook on injectable drugs c-micro comedix d.References to check compatibility of drugs in parentral administration: a.a and b e.c-most common side effect is chronic dry cough d-a good first line treatment for hypertensive diabetic e-dose should be started low and triturated gradually upward in need 63.b and c 64. zinopril 4. primaquine.. **vancomycin .Strong electrolyte B+ C 2-90% of substance X solution .arrhythmia happened due to : increase of Cardiac output ... 50% of substance X solution .. nystatin .... how mixing both to give 80% of substance X solution ? 3: 1 ** 1:3 10:30 5: 9 B+C 3-trade name of lisinopril …… Zestril ... …………increase in o2 demand dialitation in myocardium 6-digoxin differ from digitoxin : Half life Excreted hepatically .antipseudomonas drug : metronidazole ... 5. immunosuppressant agent cannot used in organ transplantation : . aldosterone) glucocorticoids (eg.which is not asthma properties : Bronchodilator Bronchospasm Increase mucous secretion Chest pain 9. phenytoin adminstration give lidocaine give digoxin immune fab electrical cardio*****…… 8. what is not recommonded?? stop digixin adminstration .In digoxin induced arrythmia .example of antimetabolite anticancer ….hormone excreted from adrenal cortex : Aldosterone Growth hormone ……… Primary product mineralocorticoids (eg. dehydroepiandrosterone) 11.. 10. cortisolndrosterone) weak androgens (eg.Excreted unchanged in urine *** 7. liquid weight = …….all of following are side effects of methotrixate except : Bone marrow depression Alopecia Nausea and vomiting *****Drive sex gland 16.about side effect of quinidine 15. volume = ……. What is specific gravity ? 14..which is not NSAID ………. 13. . .mechanism of action of antipsychotic drug : Dopamine receptor inactivation 17-drug used in hypertension and migrane : Clonidine**** Hydralazine……… 18..Predisolone 12.ACE inhibitors are contraindicated in : bilateral renal artery stenosis . 19- about cardioglycosidic effect : -ve inotropic +ve inotropic **** Hypertension Tackycardia Bradycardia 20-all factors affect on distribution of drug except : Tissue solubility Protein binding Molecular weight of drug Type enzyme response of metabolism ***** 21-all factors affect on renal clearance except : Age Sex**** Both Disease state 22- ointment used for : Carrier of drug Emollient ***Both Increase absorption Increase distribution 23-charcol used as antidote coz : Adsorption activity 24- in hypodynamic shock treatment : Use dopamine ***** Use nicotine Use aspirin 25-acyclovir used to : Herbs simplex 26- all following are viral infections except : Tuberculosis 27- about radiation 28- warfarin monitoring: Platelet formation INR The prothrombin time (PT) is the primary assay used in monitoring warfarin 29- lady take chronic warfarin , which is not true 1- avoid aspirin containing prepration 2-avoid doubling dose from herself 3-balanced food with green leaves to avoid thrombosis 4-if she pregnant, monitor INR to avoid DVT****** 5-take care about nasal bleeding 30- Which of the following is true about surgical prophylaxis ? a-it is given to treat surgery associated infections ****b-it is given to reduce the possibility of surgical site infection c-should always be given regardless type of surgery d-should be continued for 7 days after surgery e-all are true 31- Which of the following is NOT true about infiximab a-IL-1 blocker**** b-used for treatment of severe rheumatoid arthritis c-may increase risk of infections d-administered as IV infusion8 e-postadministration reactions include fever & chills 32- infusion of hypotonic solution in blood cause : a) shriniking of blood cell b) hemolysis**** c) hyperglycemia d) hypoglycemia e) b + d ? كل كم يوم تعطي الجرعة للمريض33- half life of drug is 7 days , ..... مرات4 , مرات, 3 مرتين في اليوم, كل يوم, مرة اسبوعيا يعطى مره اسبوعيا intermittent claudication. causing disorders in the peripheral perfusion. including shank ulcers.pentophyllin used for : peripheral vasodilator Hypertension Couph suppressantIndications Pentofyllin is indicated in diseases. In acute disorders of the brain perfusion.which of following is least sedative action ? Diazepam Estazolam Triazolam Temazepam *** 36. gangrene. and in diabetes.a-hyperperfusion ****b-hypoperfusion c-tachycardia d-bradycardia e-non of the above 35. including ischemic stroke and .which drug has spasmolytic action? Resirpine Amphetamine 37-desmopressine used in …… nocturnal enuresis 38-salbutamol is : Beta 2 agonist 39. atherosclerotic and inflammatory disorders. Raynaud’s disease. diabetic angiopathy. Acute disorders of the retinal blood supply.normal water used for : Eye preparption Parentral preparation Solution Emultion External preparation 43.002 0. 40-2 mg \ L solution .ceftazidime : 3rd generation . according ppm : 2 0.resultant conditions.Pka for normal water in room temperature : 7 14 10^7 10^-14 10^14 42.000002 41. P vasoconstrictive used in cardiogenic shock effective orally' S.PHARMACOKINETIC CONSTANT : Zero order 1st order 2nd order Mixed order A+B 47. IM 45.C 46.44-about aminoglycoside .about norepinephrine not true increasr B. which is not true ? Has gram –ve activity Less toxicity Narrow therapeutic Compatable with other drug Usually IV .Which of the following is NOT predinsolone side effect ? a-cataract b-hypoglycemia**** c-skeletal muscle weakness d-sodium retention e-lowered resistance to infections . c.c..c.SA node*** c-pukinje fiber d-internodal pathways e-non of the above .. 50 .c. e. b.a.d.When concidering drug therapy for hypertention . which is true? a-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-b-blokers should be avoided in asthmatic patient ****** e. e.a.The latabbreviation for " After Meals " is : a.a.ACEIs are recommended in pregnant women 53.c.p.c.. d.52 g of kcl exactly 2000 ml.The heart`s dominant pacemaker is : a.The latabbreviation for " before meal : a. c.a.A solution is made by dissolving 17.a. b. What is the molarity of this solution? 52.c.i.i..c. Once a day 51.c.48-.p.o. d. 49-.a. c..AV nod b.c..The mechanism of action of dopamine muscarinic antagonist muscarinic agonist***** nicotinic antagonist nicotinic agonist non of the above 54. dosage form of nitroglycren when used in malignant hypertension ??? IV .. infusion .55.ONE OF FOLLOWING NOT USED TO COVER BITTER TASTE : Film coat Enteric coat Granding of tablet ***** 59-ABOUT CARDIAC GLYCOSIDE ……...about albuterol side effect ……… 56. S. 60-which of following tricyclic antidepressant is tertiary amine? Amitriptyline 61. 57-solutions are better than solid dosage form coz: Accurate dose Easy to handle Morestable ****Faster action B+C 58. transdermal ****. IM ....C ..antihypertensive used in pregnancy ? Methyldopa .. . Same effect if given in the appropriate dose.drug infusion rate is 2mg\kg\hr . infused for 12 hours .Aldactone.Furosemide. for 70kg patient …. Differ in shape.The diuretic which is used with Captopril is: a. 3. c. 65. b. what is total dose 34.The term shock signifies 1.drug make urine red other than rifampicin ? 63-drug used for peptic ulcer ? Losec 64.Ethacrynic acid.62. (captopril is more potent than other ACE inhibitors) Mode of action.Differences between captopril and other ACE inhibitors: abcd- Differ in potency.all are ACEI except ……. .ACE mechanism is: abcd- converting converting converting converting Ag 11 to vasoconstrictor Ag1 Ag 1 to vasoconstrictor Ag11 Ag 1 to vasodilator Ag11 Ag 11 to vasoconstrictor Ag1 94 مسجلة برقم بالقنصلية العامة لجمهورية مصر العربيه 2. Labetalol.One of these is not like the others: a. صلية العامة لجمهورية مصر العربيه selective ß-blocker.Labetalol: nonselective ß-blocker hypertensive.ACE inhibitors are used in the treatment of: abcd- Hypertension.What are the effects of Captopril? a.ß-blocker is used for: Essential hypertension. 6.Acebutalol c. b.What is the pharmacological & / or therapeutic classification of the following drugs: a.Has a valuable role in heart failure.Which of the following is not cardio specific ß-blocker? abcd- Atenolol. Satolol. Acebutolol.effective hypotensive when others are contraindicated (B-blockers & diuretics) c.Betoxolol non selective ß-blocker.inhibits the conversion of Ag1 to Ag11 b. 94 مسجلة برقم selective ß-blocker. 8.Acebutolol: selective ß-blocker hypertensive.Timolol non b.All of the following are ß2 antagonists except: abcd- Salbutamol. selective ß-blocker. Metoprolol. Migraine. 9. Atenolol.4.B. N.labetolol non d. 10. Nadolol. 5.ß1 agonist cause: . All of the above.: Salbutamol is ß2 agonoist 11. Asthama. 7. 13.quinidine sulphate is: abcd- Anti arrhythmic agent.True 16. All of the above. Cinnarzine.Thiazide diuretics cause all the following except: abcdef- Hypokalamia.procainamide is calcium channel blocker like: abcd- quinidine (anti arrhythmic supra ventricular) Nifedipine.Thiabendazole is one of the Thiazide diuretics: a.Which one is not Ca channel blocker? abcd- verapamil. 12. 14. Hypernatremia.Aspirin. (diuretic increase excretion of sodium chloride but lessens potassium). Hyponatrimia.False 94 مسجلة برقم نصلية العامة لجمهورية مصر العربيه b. Hyperglycemia.Paracetamol. Increasing intotopic effect. c.Triamterene. Hypercalcemia.Potassium supplement therapy must not be given with: a. A & C. 15. Anti malarial agent. Lisinopril. Hyperuricamia. Deltiazem. 17. Increasing ectotopic effect. b.abcd- Increase in oxygen consumption. Amlodipine. Cilazapril. . Anti hypertensive agent. d.Nitroprusside Na is: abcd- Potent vasodilator.Dobutamine is used as: abcd- parasympathomimmetic. 24. Hydroatropine. All of the above. Butrepium bromide. 22. because: 94 مسجلة برقم نصلية العامة لجمهورية مصر العربيه abcd- It is not stable in gastric acid of stomach.Hypotension. 20. Anti arrhythmic agent.All these drugs are anti-cholinergic except: abcd- ipratropium. Benzatropine methylate.Decrease heart rate. 23. Dobutamin.V.Hydrazine is used as antihypertensive through: . 21. b.Increasing in heart rate and increasing in blood pressure . Potent vasoconstrictor.Dobutamine is given I. It is eliminated very quickly. Hypotensive agent.Piroxicam. Ipratropium bromide. In cardiac surgery. It is needed in large doses if taken orally. Potent diuretic. 19. Atropine sulphate.Epinephrime has Alpha and Beta agonist activity so cause: a.All of these are anticholinergics except: abcde- Atropine sulphate. Mebeverine. 18. c. It causes nausea & vomiting orally. Diuretic. Urokinase. URI. 31.Cefaclor.Ipeca is emetic agent which induces emesis through: abcd- Stimulation of the stomach. b. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه 30.Which one has vasodilator effect? abcd- nicotinic acid. Stimulation of the CTZ. Urinary tract infection (UTI). thrombotic.abcd- Vasodialaton. Inhibition of the stomach through CNS. A & B. GIT infection. 29. Hydralazine.Zinnat contains: a. 28.Cefuroxime. 26.Which one of the following has vasodilator effect? abcd- Nicotine Cholestyramin.fibrinolytic). All of the above. 27. Nalidxic acid. Vitamin A.Which of these has no vasodilator effect? abcd- Methyl dopa. anti. (anti-coagualant.Theophylline is: . Vitamin A. Decreasing cardiac output. Urikinase. Enalapril. Prazocin.nintrofurantion is indicated for: abcd- viral infection. 25. Increased metabolism & dose must be increased. All of the above. Causes bradicardia.Decresed metabolism & dose must be decreased. 33. Acetate. The trade name of clotrimazole.Urine flow rate.Triazole is: abcd- Antifungal. Sodium. Cimetidine. ß2 agonoist. Nyatatin.The modern method to treat asthma is to use: abcd- Long acting bronchodilator + corticosteroid. 38. . Long acting bronchodilator only. The trade name of amphotrecin B. CNS. Short acting bronchodilator + steroids.Treatment of anaphylactic reaction is indicated in the following except: abcd- Hydrocortisone.All of these are anions except: abcd- Phosphate.Which minoxidil. all these parameters should be monitored except: a.abcd- Broncodilator. Corticosteroid for long period of time. Seizures. b.Theophylline does in children: a. 36. Epinephrine. c. 32. Paracetamol poisoning.Introduction of emesis is not indicated in the following except: abcd- Caustic substance ingestion. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه 37.Decresed metabolism & dose must be increased. Chloride. Human albumin. 35. 34. 43.famotidine is H2 antagonist used for: a.9% contains 4.Prophylaxis from gout.Type 1 diabetes advises to use: abcd- Insulin.Vasopressine is used for the treatment of: abcd- Diabetes insipidus (used in bleeding oesophageal varices) Diabetes mellitus type I.b. b. Diet control.Pivampicillin. All of the above. Hypertension. None of the above.Body weight.Which one is prodrug: a.Ampicillin. Diabetes mellitus type II. A & B. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه 44. 40. Insulin. 41. Glibenclamide.5 gm.Treatment of high uric acid & calcium oxalate renal stones.Type 2 diabetes advises to use: abcd- Sulphonylurea.Enalapril is the prodrug of: Enalaprilate. 42.Give two indications for allopurinol: a.Blood pressure.500 ml normal saline 0. c.Treatment of gastric & duodenal ulcers. . 39. 45. Nacl. 46. d. b. c.Pulse rate.Erythromycin. All these medications are used in the treatment of T.One of the following should be avoided in pregnancy: abcd- Vitamin A. except: abcd- INH.B. Calcium. Misoprostal. Used for the upper respiratory tract infection. 53. Ethambutol.Which one of the following is contraindicated in pregnancy? abcd- Ciprofloxacin. Cyclosporine.acetohexamide (one of silphonyl urea) is hypoglycemic. A & B.misoprostol [cytotec = prostaglandin] inhibits gastric acid by blocking hydrogen-potassium adenosine triphosphate enzyme system [ATP] of gastric cell: a. 48. 51.Which one of the following is not contraindicated in pregnancy? abcd- Methyldopa. Lisinopril. Chlorpheniramine. Captopril. Contraindicated in pregnancy. Paracetamol.Simvastatin is used for hypolipidemic action.47.Cytotec is [misoprostol]: abcd- Used for gastric & duodenal ulcer. 50. 94 مسجلة برقم ية العامة لجمهورية مصر العربيه . 52. 54. Sucralfate. 49. Enalapril. Rifampicin.True b. Cycloserin.False. 59. 58. Aluerin. For influenza B. Influenza. the drug of choice is: a.The duration of treatment of T. Acne. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه 61.isoniazide.All these drugs are antiviral except: abcd- amantadine. Six month & over. For influenza A. spasmonal) 60. Two week. Calcium supplement. 57.Amantadine is used for all of the following except: abcd- Antiviral. by CTC is: abcd- One week. One month.55. (anti spasmodic. Riketssia. Herpes zoster. c. Acyclovir. Anti-parkinsonis m. Zidovudine.All are viral infection except: abcd- Hepatitis B.B. Hypertension. 56.calcipotriol ( daivonex) is indicated for: abcd- Psoriasis.Isonicotinic acid hydrazide. .Epinephrine [same adrenaline = a hormone produced by the adrenal medulla on mammals].INH means: a. b.At the cardiac arrest (shock).A & B. Saline solution. Lidocine.What is the most drug can cause damage if it is given OTC? abcd- Warfarin.Ciprofloxacin. 64.Cardiac arrest could be managed by the following except: abcd- Ephedrine.Simple analgesic. Unionized lipophilic. 68. Antacids. Chlorothiazide. c. Rifampicin.Propranolol. 65.Which one is an OTC drug? a. Captopril.Drugs to pass B.B. 63. c. d. Normal saline. should be: abcd- Unionized hydrophilic. 67.b. Increase metabolism & decreases response. Tegretol.All are non OTC drugs except: 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه . Ionized hydrophilic.B.Hydrocortisone. 66. Decrease metabolism & decreases response. Propranolol. b. Ionized lipophilic.chloramphenicol affects liver inhibitory enzyme. 62. Increase metabolism & increases response. so: abcd- Decrease metabolism & increases response.All are OTC drugs except: abcd- Biscodil Aspirin.Warfarin. 70.abcd- Bisacodyl. Analgesic. 74. Sympathomimmetics. c. Maalox. For runny nose. All of the above. Tegretol. b.All of these can be dispensed without prescription except: abcd- Aspirin. 75. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه . Carbamazepine.Tween.Span. None of the above. All of the above. Bisacodyl.The concentration of the drug on expiration date is: abcd- From 90-110%. 71.Mammalian glands stimulation.Na lauryl sulphate. 73.Surfactant not used orally: a.Morphine & morpin are similar in: abcd- Addiction. 72.Uterine stimulation. Metformin. Phenytoin. 69. Vasoconstrictor and pressor (raise blood pressure). Miosis.Cytocin is one of the posterior pituitary hormones. b. Not less than 100%. Not less than 90%.Phenylephrine is used for: abcde- Decongestant.Oxytocin produces all the following except: a. Four medicines including antibiotic. 82.Cefixime.Binding to plasma protein: a. 76.in case of osteoarthritis & peptic ulcer of elderly patients use: a. 81.All these can be used in leprosy except: abcd- Dapsone. Clofazimine. b.Progesterone release. A & B. 79. b. Miconazole.Maximum use of paracetemol is: . Rifampicin. [The drug of choice in leprosy].Strong NSAIDs. Analgesic.Paracetamol.Which one is sporanox? abcd- Itraconazole. c.N.New & best therapy for peptic ulcer is: a. Meniere. (antifungal). c.Betahistine dihydrochloride: abcd- Antihistaminic. d. I.Use more than H2 antagonist.c.Antacid + H2 antagonist.Suprax is: a. 77. 80. b. b. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه 83.H.Decreases half life. 78.Increases half life. Clotrimazole. Econazole.Itraconazole.Labor induction.s disease.Aspirin. Has an anti-emetic effect.Diclofenac potassium. 85. c. .5 gm in 8 hours. Ceprodoxin. 84. All of the above. Mycobacterium.Pneumocystis Carini Pneumonia [PCP] is: abcd- Parasite. 90. 87. Bacteria. 7.Diclofenac sodium. 86.Immunocompromised means? Low resistant to infections. 94 مسجلة برقم 91.5 gm in 4 hours.Voltaren Emulgel is: a.Cyproteron (Androcur) is used for: Increasing the sexual abilities. Finasteride. Virus.Cefprozil. 7.Immunocompetent means? Control resistant to infections. 89. 88.Which one the following is not antibiotic? abcd- Erythromycin.Flumazenil.Metoclopramide is a dopamine antagonista: abcd- Acts centrally by blocking chemoreceptor trigger zone. b.5 gm in 48 hours.Dicolfenac Diethlamine. Acts peripherally. b. (proscar).Which one of the following is used in Benign prostatic hyperplasia [BPHP]? صلية العامة لجمهورية مصر العربيه a.Finasteride. 7.abcd- 4 gm in 24 hours. c. Cefprozil. Desflurane. Atovaquone. Anti-coagulant. 94. 98. Aldesleukin. 92.Xylometazolinel.Which one of the following is not mucolytic? abcde- Bromhexine.Which one is Antiplatelet? abcd- Ticlopidine hydrochloride.All these drugs are fibrinoltic except.Treatment of uric acid and co-oxalate renal stones. b. Anticholinergic. c. Antibiotic. 93. Ambroxol. Anistreplase.Aspirin. Carbocisteine.d. 96. 95. Dextromethorphan. Dipyridamole.Otrivin is: a.Ticlopidine is used as: abcd- Antiplatelet.Prophylaxis of gout. Guaifenesin. abcd- Urokinase.A & B. b. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه .Indication(s) of Allopurinol is (are): a. Streptokinase.Phynylepherine.Mevacurim. 97.All these are anti-platelets except: a. Decreasing the activity of liver enzymes.Which one is not oral anti-coagulant? abcd- Warfarin. 99. Dysmenorrhea. Ancord. 104. 100.Decreasing the activity of liver enzymes. Verapamil.Increasing the activity of liver enzymes. Dipyridamole (antiplatelet). 102. (deep vein thrombosis) 103. 101. So increases the activity of warfarin. Presentin. Influenza symptoms.All these are anti-coagulant except: abcd- Warfarin. Phenidione. when taken with warfarin anti-coagulant leads to: a. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه . Rifampicin. b. Enoxaprine.Increasing the activity of liver enzymes. Streptokinase. Heparin. Nicoumolone. So decreases the activity of warfarin.V.bcde- Dipyridamol. Vitamin K. So increases the activity of warfarin. c. abcd- Anti-coagulant. d. Chicken pox.Anti-coagulant effect of warfarin is decreased by: abcd- Aspirin.Aspirin is recommended with one of the following.Enoxprine (I. Ticlopidine. anti-coagulant) is taken every: 6 hours.Phenobarbitone induces liver microsomal enzymes. 106. Phenobarbitone. 108. Oral contraceptive.Give the antidote of each of the following drugs. Chloramphenicol. 110. -Pencillamine.So decreases the activity of warfarin.Which one of the following is an enzyme inducer? abcd- Rifampicin. (organic compound) -Dextrose. Vitamin C. Heparin Paracetamol Warfarin Iron Cyanide Copper & Lead Heavy metals مسجلة برقم Insulin & oral hypoglycemic مصر العربيه94لجمهورية صلية العامة Digoxine . 109. -Desferroxamine (chelating agent). 105. -Protomin Zinc. -Acytylcystiene. -Vitamin K. -Dimercaprol. Vitamin C. Vitamin C. Cimetdine. Metronidazole. Cimetidine. Vitamin K.Drug which decreases [antidote] the action of warfarin is: abcd- Carbimazole.Which one reduces the metabolism of other drugs in the liver? abcd- Rifampicin. Phenobarbitone. -Na thiosulphate.Which one induces the metabolism of other drugs in the liver? abcd- Rifampicin. None of the above.Drug which increases the action of warfarin is: abcd- Carbimazole. -Protamine sulphate. Metrinidazole. Oral contraceptive. Cimetidine. 107. Salt solution.The antidote of heparin available in fish is: Protamin sulphate. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه . Ketoconazole.To prevent more toxicity of digoxin we use antidote which is: abcd- Digbind. 114.-Noloxone. 112.Hypoglycemia. b.Give an example of a drug inducing hepatotoxicity: abcd- Paracetamol. 115.A-V block. Opioid Morphine 111.Heart block. Digotoxin. 116.Thyrotoxicosis. Ketoconazole. Saline. b. -Naloxone. Charcoal. c. 117.Hepatotoxicity is induced due to these drugs except: abcd- Rifampicin. c. Water. Saline.GIT upset.The cause of death in morphine toxicity is: a.To prevent more absorption of the toxic drug we use: abcd- Charcoal. Dipyridamole. Quinolones. Quinolones.The common side effect of sulphonylurea is: a. Rifampicin.Respiratory failure. 113. d- All of the above. 118- The side effects of insulin are: abcd- Local reaction.(urticaria) Hypoglycemia. Fat dystrophy at the side of injection. All of the above. 119- One of the following is the main side effect of insulin: abcd- Hypoglycemia. Fluid retention. Hyperglycemia. All of the above. 120- Pseudomembranous colitis is a side effect of: abcd- Clindamycin. Vancomycin. Reserpine. INH. 121- All these are side effects of chloramphenicol except: abcd- Irreversible a plastic anemia. Optic neuritis. Peripheral neuritis. Iron deficiency anemia. 122- All of these are corticosteroids except: abcdef- Methyl prednisolone. Prednisolone. Triamcinolone. Beclomethasone. Dexamethasone. Ondansteron [5HT3 receptor antagonist, anti emetic]. 123- All of these are anti-neoplastics except: abcd- Aldesleukin. Teniposide. Pentostatin. Amlodipine. 124- All of these are antimetabolites (cytotoxic) except: a- Methotrexate. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه bcdef- Cytarabin. Azathioprine. Mercaptopurine. Fluorouracil. Cyclophosphamide. 125- Levodopa is used with Carbidopa for the treatment of Parkinsonism. 126- All of these are true for Levodopa except: abcd- Precursor of dopamine. Stimulates dopamine. Effective in Parkinsonism. Does not pass B.B.B. 127- Specific Serotonin reuptake inhibitors are used as: abcd- Antihistaminic. Antidepressant. Antihypertensive. Anti-emetic. 128- Fluoxatine (Prozac) is: a- SSRI antidepressant. b- Selective Serotonin Reuptake Inhibitor. c- A & B. 129- Ondansetron HCI is used for: abcd- Emecis. Anagina pectoris. Prophelaxis of migraine. Hypertension. 130- Which one is not 5 HT3 antagonists? abcd- Tropisetron. Ondansetron. Granisetron. Domjperidone, (peripheral dopamine receptor antagonist) 131- The drug of choice for febrile convulsion in children is: Diazepam 250 microgram / Kg. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه 132- Which one is correct? abcd- Diazepam is not used for long time. Diazepam is taken I.M. only. Diazepam is derived from morphine. Diazepam can cause muscle spasm. 133- Drug of choice in status Epilepticus is: Diazepam. 134- The following are the indications of Diazepam, except: abcd- Antipsychotic. Epilepsy. Hypnotic. Headache. 135- All the following used in treatment of anxiety except: abcd- Propranolol. Diazepam. Mebrobamate. Homotropine. 136- All of these are anti-parkinsonism except: abcdefg- Amantadine. Bromocriptine. Selegitine HCL. Lysuride. Pergolide. Levodopa. Primidone. 137- All these drugs can be used for Parkinsonism except: abcd- Selgitine HCL. Carbidopa. Pergolide. Nedocramil sodium. 138- One of the following is not used for epilepsy: 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه Zidovudine is used for: HIV. -Niacine -Panthothenic acid. 140. Nedocromil sodium (tilade inhaler). abcd- Vitamin B1 Vitamin B2 Vitamin B3 Vitamin B5 Vitamin B6 Vitamin B9 Vitamin B12 144.Controlled drugs present in pharmacy are: In tightly closed shelves. 139.One of the following not used in epilepsy: abcd- Clonazepam. P. -Pyridoxine HCI.All of the following are controlled drugs except: abcdefghi- Rivotril. Barbiturates. 143. -Riboflavin. Imipenem. Phenytoin.U. -Folic acid. 141. Epanutin.abcd- Clorizepam.Give the name of: -Thiamine HCI. Phenytoin. Imipramine. 142. AIDS. Stesolid. Primidon. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه . Diazepam. Primidone. Imipramine (tricyclic antidepressant).All the following used in epilepsy except: abcd- Sodium valproate. -Cyanocobalamine. A & B. Phenytoin. Carbamazepine. Primidone. Carbamazepine. G & H. 150. c.Schedule of immunization of HBV is: abcd- Single does. b.Maximum recommended dose of Ibuprofen is: abcd- 800. 3000. 149. 148.There is one drug used for HIV.Hepatitis vaccine does is: a.Meningococcal polysaccharide-Measles-Rubella V. Five days. . Three dose. c. Kinasterdin.M.Three times / year. / 4-6 hours. 2400. 152. paracetamol dose for him is: a.Blocks the hydrogen-potassium ATP enzyme system. 147.Omprazole: a.A & B. abcd- Zaloltabin.Maximum dose of captopril is 150 mg / day.M.Acts as proton pump inhibitor.Measles-Mumps-Rubella V. Cefaproxil.Twice / year. b.100-150 mg. Enoxacin. 146. 1600. Two dose.Once / year.Child of 10 Kg.R. b.Measles-Mumps-Rabies V. c. vaccine is: a.145. 151. Maximum dose of Diclofenac sodium is: abcd- 50 mg.125-250 mg. b. NPH type.Insulin which can be given I. Regular insulin. b. Vitamin A daily dose for therapy Is 100. 100 mg.Insulin is preserved at: 2 – 80 C.All of above . 159.Storage of cream & ointment below 50 C causes cracking. 75 mg. 161. Amorphous insulin. / 4-6 hours. / 4-6 hours.One of the following insulin is given once daily: abcd- Protamine zinc insulin. d.V.b.Drug is used for Leishmania: .When you store drug at low temperature you must consider the following: a.000 – 200.000 IU.000 – 50. 155. 157. 156.Storage of insulin below 00 C causes aggregation of insulin.000 IU. c. 153. 158. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه 154. Neutral insulin. c. c. is: abcd- Regular type.A & B are correct.Maximum dose of Paracetamol is 4 mg.Storage of dusting powder below 00 C causes the accumulation of granules. 30 / 70 type.Biosynthetically by recombinant DNA technology using E-coli.Vitamin A daily dose for the correction of deficiency Is 30.250-500 mg. / day. None of the above.Source of human insulin is E-coli by: a. 160. None of the above.Semi synthetically by enzymatic modification of protein material. c. c.Which is not from quinolone group? abcdefghij- Nalidixic acid.Cefprazone. Ciprofloxacin. [antimalarial] H & I.Are ineffective when taken orally. [fluroquinolones] Ofloxacin. 165. b. Eoxacin.All these are natural estrogens except: abcd- Estradiol.Na cromoglyconate. Estrone.Na stiboglyconate. Lemofloxacin. Sparfloxacin.a.Reduces the incidence of coronary diseases in postmenopausal women. Mestronol (androgen). Norfloxacin. . c. b.Do not affect children. Quinine. b. Aminosidine.Affect joints.Lomifloxacin. 164. Estriol.Quinolones are contraindicated in children because: a. 163. c. Ciprofloxacin. b. 162.Co-trimethoxazole contains: Trimethoprim + sulphmethoxazole. 167.Can be taken for life time.Affect liver.Mebendazole. 166.Estrogen: a.Zalcitabine.All these drugs are antibacterial except: 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه a. 171. Constipation. Iodine. Carbimazole. (for treatment only) 170. Ibuprofen. Nedocromil sodium. 172. 94 مسجلة برقم لية العامة لجمهورية مصر العربيه .168.Which one of these drugs is drugs of choice for Myxodema (hypothyroidis m)? abcd- Thyroxin sodium.All of the following for prophylaxis if asthma except: abcd- Ketotifen. Prednisolone.Benzyl peroxide is a local treatment for acne vulgaris. Codeine.All of the following are NSAH (nonsedating antihistamin) except: abcd- Loratidine.The drug of choice for treatment of amoebae is: a. Vomiting. Cetrizine. Diarrhea. Azotodin. Salbutamol. 173. Propyl thiouracil.Which one of these drugs is not used for acute pain? abcde- Naproxen. Control of epilepsy.Sumatriptan is used for: abcd- Treatment of migraine and headache. 174. Hypertension 169. Astemizole. Clochicine. 175. Sodium cromoglycate.Metronidazole.Which one of these symptoms does not occur with morphine? abcd- Respiratory depression. Angina pectoris. b.Elimination of digoxin is mainly by: abcd- Kidney. Terbinafine Miconazole Amphotercin Griseofulvin 181. None of the above. c. Eczema. d.Tetracycline.Gentamycin. 176. Direct proportion to the rate of administration. = Parentral only. Indirect proportion to the rate of administration.Chloramphenicol.The steady state concentration of the drug in the plasma depends on: abcd- Direct proportion to the rate of elimination. Candida sp.CNS disturbance.Drug physical dependence is as same as drug abuse.What is the mechanism of action of vitamin K? Vitamin K has an essential role in the synthesis of coagulation factors by hepatic cells. None of the above. 178. 182. 179. = Local & systemic. A & b.False.What is difference between the following antifungals? = Local & systemic. 94 مسجلة برقم ية العامة لجمهورية مصر العربيه 177. b. .Amiloride as a treatment causes: a.Hyperkalaemia. a. c.Terbinafine is used topically for: abcd- Fungal infection. 180. b. Indirect proportion to the rate of elimination. Liver. and increases formation of clotting factors.Hypokalaemia. = Oral.True. Which one is not tetracycline? abcd- Minocycline. 190. Active & poorly absorbed Inactive & not absorbed Active & absorbed.Give the indication of the following drugs: = for hyperlipidaemia. Doxicycline. 184. Jamicain.1st generation cepharosporins.183. Demeclocycline. Gimfibrazole Cisapride Fluxetin Inhibitor Carbimazole Imipramine Ipratropium bromide 185. iron and aluminium forms a chelate which is: abcd- Inactive & poorly absorbed. 189. = for gastro-oesphegyal reflux. 188. b.Cefaclor is: a. Gentamycin. Clindamycin. c. 186. Kanamycine.Tetracycline with Ca & Mg: Poorly absorbed compound from GIT.Use of tetracycline in its expiry date make syndrome called: Farconi syndrome.2nd generation cepharosporins.Tetracycline when taken with minerals such as calcium. 187.Moduretic is a combination between: Amiloride + hydrochlorothiazide.Teicoplanin antibiotic has similar effect on gram positive bacteria as: abcd- Vancomycin. = tricyclic antidepressant. = SSRI as sedative serotonin reuptake = = hyperthyroidis m.3rd generation cepharosporins. 94 مسجلة برقم لية العامة لجمهورية مصر العربيه . = anti muscarinic as bronchodilator. Biotransformation is: a.Less lipids soluble.Bioavailability of the drug is: a.More lipids soluble.All of these are antibiotics except: abcd- Cefopodoxin.Rate of absorption. D.Imipenam (carbapenam) It is the first thiemamycin ß. b. c. 198. b. 94 مسجلة برقم لية العامة لجمهورية مصر العربيه .lactam antibiotic.Metoclopramide is a dopamine antagonist acts centrally by blocking chemo-receptor Trigger zone & peripherally acts on GIT to be used as antiemetic.What is the definition of Bioavailability of the drug? Is the quantity of the active constituent of the drug absorbed by the blood through the intestine or any other route in a certain period of time? OR: Is the concentration of the drug in the blood in a ascertain period of time.Extent of absorption.Mesalazine is used for the treatment and maintenance of remission of ulcerative colitis. 193. Used for acne.191. E and K. 194.Mention four lipid soluble vitamins. Broad spectrum bactericidal. Vitamin A. 195.Rate & extent. 192. Inhibits protein snthesis. Cefaprozil. 196. Zaloltabin.Which is not true with tetracycline? abcd- Broad spectrum bacteriostatic. 199. Loefloxocin. 197. Bentonite.Warfarin b. Cefotaxime. Clozapine.Potassium sparing K.Vitamin K . b. None of the above. Calamine.Omeprazole is: Losec (proton pump inhibitor) 201. 202.Aspirin. Sodium sulphate.ACEI 203. a.INH h.All of these are third generation cephalosporins except: abcde- Cefixime.Congestive heart failure. 206.Warfarin c.Warfarin d.Which one is not benzodiazepine? abcd- Temazepam. Sodium citrate.Phenobarbital .Renal failure. Cefopodoxime. except: abcde- ZnO.Digoxin i. Ceftraxone.Insulin . 205.Heparin g. Loprazolam. .All of these are the components of calamine lotion B.Insulin .200.Phenobarbital .Oral rehydrate solution is one of the following: 94 مسجلة برقم لية العامة لجمهورية مصر العربيه .Example of drug-drug interaction: .P. Nitrozepam.Warfarin e. 204.Mention two diseases cause Edema: a.Spironolactone . Drugs need monitor for their serum lavel: Amikacin Warfarin Theophyline Digoxin. Na citrate + KCl + NaCl. Provastatin and Fluvastatin. 208. 211. Increases HDL & triglysrides Increases HDL & LDL. 210. methyl cellulose and psyllum? The adequate fluid intake should be maintained to avoid intestinal obstruction.25 dihydroxy calciferol. Simvastatin. It is activated by penicillinase enzyme.For fluxacillin.1.2 dihydroxy calciferol .Caciferol is: a. all these statements are wrong except: abcd- It is better absorbed than Cloxacillin. 213.Mention drugs from HMG-CoA-reductase inhibitor.What are the instruction for the patient take Metamucil or any other bulk foaming laxative as Bran.1. It is base stable. 214. 212.Gemfibrozile: abcd- Increases HDL & decrease triglysrides. Increases LDL & triglysrides. 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه 209. Na citrate + KCl + NaCl.For hyperlipide mia we use: Gemfibrozile. 207.HMG-CoA-reductase inhibitor is: 3 hydroxy. It is taken by oral route only. 3 Methyl Glutoryl CoA reductase inhibitor.abcd- NaCl + K citrate + Na citrate + glucose. b. NaCl + KCl + NaHCO3 + citric acid. 215. 216.Physiological and biochemical effect of the BODY on the DRUG.Bactrim (co-trimazole ) is: a. 8 am – 11 pm.Physiological and biochemical effect of the DRUG on the BODY. gluconate. 222.Ferrograde is: abcd- Ferrous Ferrous Ferrous Ferrous sulphate.Physiological and biochemical effect of the BODY on the DRUG.3 dihydroxy calciferol. d.The most common chemical structure of iron in drug is: Ferrograd (ferrous sulphate). c. 218. 217. 11 am – 8 pm. 221. Increase heart rate.Impenem (carbepenem) is: First thienamycin ß-lactam antibiotic. 220.None of the above. c.Sympathomimetic drugs: abcd- 94 مسجلة برقم ية العامة لجمهورية مصر العربيه Increase blood pressure. fumarate. 223.Trimethoprim + sulphamethoxasole.None of the above.2. Increase coronary flow.Pharmacokynetic means: a.Pharmacodynamic means: a. b. 11 am – 11 pm.None of the above. citrate.Isomack 20 mg tablets taken twice daily at time interval between: abcd- 8 am – pm. All of the above.Physiological and biochemical effect of the DRUG on the BODY.Valtrex is: . b.c. 219. b.Trimethaprim + sulphonylurea. 8 230.How much lidocaine for solution of 1/1000 to obtain 30 cc: abcd- 0. b.When drug is used for U. 225. it should be: abcd- G-ve.3.T.Hypertension.2500 ml. None of the above.Micromedex is: Computer system.03.Keflex is: abcd- 1st generation cephalosporin. 228. b. and to obtain we should add what volume of H2 O to get percent dilution 3 (H2 O) : 1 (NaCl)? a. 94 مسجلة برقم ة العامة لجمهورية مصر العربيه .1500 ml. 2nd generation cephalosporin 3rd generation cephalosporin 4th generation cephalosporin. c.3000 ml.In a bottle we have NaCl 500 ml.Hypotension. 224. 226.Acyclovir. c. G+ve.I. 229. 227. BOTH.Clonididne used in: a. None of the above. 0.None of the above.Grain equal: 64. 30. Isoptin is present in market in concentration: 240 & 80 mg.Patient having constipation not to take: Morphine. 232. 94 مسجلة برقم ية العامة لجمهورية مصر العربيه . 240.Klacid is used every: 12 hours. c.V.231. c. 237. Voltic. 238.Intrathecal means: Interjoint (spinal cord). Parafon. None of the above.Olive oil + Water + Asq gives: a.One of the following is not NSAID: abcd- Xefo. 235. 236.C.S.Suppositories. b.I.One of the following has faster systemic action: a.I. 234.M. 239. b.Alcohol present in pharmacy as antiseptic is in concentration: 70% 241.Natural emulsifying agent: Gum acacia.Isoptin is used in treatment of: Supraventricular arrythi. 233.All of these are precautions of becotide except: Used only at the attack of asthma.Emulsion.Solution. The drug metabolism in the body occurs in: abcd- GIT & plasma. DDT. 244. Liver.The drug transfers through cell membrane by: . Active while the free part is more active.Which is present in balms or liniments & not used inburns? Methyl Salicylate. kidney and bowed mucosa.Intralipids are: O/W emulsion. Glycerin phenol. All of the above. 247. Glycerin magnesia. 249. abcd- Pyrithrins.242. Prevention of conversion of acetaldehyde to acetic acid. Imidazole. Gut wall during absorption & I plasma stream. Gut wall during absorption. 243.Zantac contains: Ranitidine. Less active while the free part is active. 248. 94 مسجلة برقم 246.One of the following preparations used as optic drops for dewaxing: صلية العامة لجمهورية مصر العربيه abcd- 5% glycerin bicarbonate. Primido.The drug of choice for head lice.Disulfiram is used for: abcd- Treatment of chronic alcohol dependence.Protein bounds to drug forming a compound which is: abcd- Inactive while the free part is active. 245. 5% alcoholic bicarbonate. Protection of lover cells from alcoholism. 250. Highly active while the free part is inactive. None of the above. Roxithromycin. Makesskeletal mscle relaxation as the effect of parasypathomimmetics.Clonidine is used as: abcd- Antihypertensive.Astemizole is a long acting non-sedating anti-histamine. 255. None of the above. A & B is correct. ß1 antagonist. 253. Lipid dissolves. Clindamycin.Metoclopramide gives anti-emetic effect through: abcd- Peripheral action. Muscarinic receptors. H2 antagonist.New non-selective antihistamines act through: abcd- H1 antagonist. 94 مسجلة برقم لية العامة لجمهورية مصر العربيه . Dopaminergic receptor. Help the sleeping effect of anaesthesia. Treat the side effect of anaesthesia.Atropine is used as pre-anaesthetic to: abcd- Decrease saliva. Muscarinic receptors. 257. A drug which prevents the recurrence of migraine. 254.All the following are macrolides except: abcdefg- Clarithromycin. Erythromycin. 252.Give an example of no sedating anti-histamines: Loratidine – Cetrizine – Terfenadine. Osmotic pressure. A & B. Azithromycin.abcde- Aqueous diffusion. Apiramycin. All of the above. Sisomycin. 251. 256. 263. Nedocromil sodium.All these are antibacterial except: abcd- Lomefloxacin. Cefpodoxime. 260.Benzyl peroxide is alcohol treatment for: abcd- Acne vulgaris. Tadenn. 259. Antimalarial. Cefprozil. 262. Gentamycin.Tilade inhaler generic name is: abcd- Azelastine HCl. Anthelmentic. Carbimazole.The main use of metronidazole is: abcd- Anti amoebiasis. Zalcitabine.Telcoplanin antibiotic affect on G+ve bacteria similar to: abcd- Vancomycin.F & G. Sodium cromoglycate. Rheumatic pain.All these are broad spectrum cephalosporin except: . Kanamycin. Antibiotic. Angina pectoris. Dysmenorrheal.The drug of choice in myxodema (hypothyroidis m): abcd- Thyroxin sodium.h. Neomycin. Budesonide. 258. Propyl uracil. 264. 94 مسجلة برقم لية العامة لجمهورية مصر العربيه 261. 265.Which one is not aminoglycoside: صلية العامة لجمهورية مصر العربيه abcd- Netillmicin. Aminosidine sulfate. 269. Gentamycin Mikacin. Tuberculosis. Kanamycin.Give two side effects of aminoglycosides: Nephrotoxicity – ototoxicity.Give an example of a frug inducing nephrotoxixity: Aminoglycosides as Gentamycin.Aminoglycosides are: abcdefgh- Tobramycin.Baclofen is used for: abcd- Antiseptic with spinal site of attack. Tobramycin. Chlorides. Bicarbonates.Expectorants are: Iodides. Cefuroxime. Meningitis. Tobramycin. Cefopodoxime. None of the above. 270. Cefotaxime.abcd- Cefexime. 266. . 268. 271. Streptomycin. Amikacin.Which aminoglycoside antibiotic can be taken orally? abcd- Neomycin sulphate. Netilmicin. Sisomycin. 94 مسجلة برقم 267. Lymecyclin. Kanamycin. Neomycin. 274.G-6PD deficiency patients must not take: abcd- Cotrmazole (sulphonamide). 94 مسجلة برقم لقنصلية العامة لجمهورية مصر العربيه 275. Tuberclosis. . the drug may cause haemolysis: abcd- Sulphonamide. Dexamethasone.Praziquentel used for Billhariasis: a. Paracetamol. b. Guaiphenesin.Pentobarbital (often used as pre medication in children) differs from phenobarbital in: a. 276. Ketoconazole. Hydralazin. 272.Acetates. Leprosy. Ipecauanha. None of the above.A & B.Caused loss of intercellular calcium of the worm. b. Squil. Enalapril.Long duration.Which of the following has no vasodilating effect? abcd- Methyldopa.Has trade name Biltricide. Pencillin. 273. Prazosin. Pencillin.Patient with G6 phosphate dehydrogenase deficiency. Creostesl Volatile oils. 277. c.Acitretin is used for: abcd- Oral treatment of severe forms of psoriasis and disorders of keratinization. Paracetamol.Faster in action. Generic and trade names of sulphonylurea: = diabenase. = Amaryl. Hyoscine N butyl bromide Propantheline bromide Oxyphenonium Mebeverine HCl Alverine 282. = Dimilor. = Cinopal. 279. None of the above. Chlorpropamide Glibenclamide Glicazide Glipizide Tolbutamide Acetohexamide Glimipiride 281. Acetyl salicylic acid Ibuprofen Diclofenac sodium Fenbufen Diflunisal Indomethacin Ketoprofen 94 مسجلة برقم ية العامة لجمهورية مصر العربيه .Relieving some neurological complications e.Generic and trade name of antispasmodic drugs: = Buscopan & Scopinal. = Indocid. deafness. = Brufen. = Anternyl. the formation of glucose and glycogen from protein) used in: abcd- Bronchial asthma.All of the above.Use of calcitonin: a. A & B.To lower plasma Ca concentration in some patients with hyper calcaemia (excessive calcium in the blood. i. = Profenid. c. = Daonil & Euglucon. b. = Probanthine.Generic and trade name of NSAIDs: = Aspirin. = Voltaren. 280. = Dolobid. = Diamicron = Minidiab = Rastinone. = Duspatalin. Addison disease.g.278. indogesic and Rothacin. = Spamonal. d.Glucocoticoids (any steroid hormone promotes gluconeogenesis.e.Treatment of Paget disease (hypercalcemia associated with pain). S. = Xenical. = Lioresal. = Losec. = Neotigasone. Naproxen 283. 1% according to U. 287. 1980. = Ipradol.5% according to B. Dextromethorphan.P. = pondocillin.Antiseptic. 94 مسجلة برقم ة العامة لجمهورية مصر العربيه . Pindolol Baclofen Omeprazole Acitretin Isotretinoin Orlistat Hexoprenaline Khellin Sildenafil Pivampicillin Bufexamac Codergocrin Acarbose 285. = Lynamine.Skin disinfectant. = hydergine.The concentration of crystal violet paint is: 2.Give six generic names of cough sedatives: Codeine. 1985. Cloroquine Primaquine Pyremethamine + Sulfadoxine 284.P. = Glucobay. 286.= Naprosyn. = Droxaryl.Use of gentian violet (crystal violet) : a.All of the above.List of the trade name of the following: = Visken. = Roaccutane. = Malarex & resochin. = Pansidar. c.Generic and trade names of anti malarial drugs. = Viagra. = Primaquine. b. Phlocodein. Enteric coated tablets : Are dissolved in the intestine and not affected by the stomach juices e. anthelmentic.What is the concentration of mercurochrome solution? 2%.Sustained release tablets depend on: PH of stomach. The dose is very high. Stomach Ph. 292. The dose is not sufficient. 293. you should call the doctor to tell him: abcd- There is no need to call the doctor. Ignore the case.Controlled released drug delivery depends on: abcd- Ready programmed & no influence of the body fluid.Methodone. Morphine. what can you advice him? abcd- Go to a hospital.g. 288. 291. Passes the stomach & releases in the intestine. The dose must not exceed 180 mg daily.A patient of 10 kg is given a paracetamol one teaspoonful every 4-6 hours.A child of weight 10 kg. 290. Enzymatic reactions. Body fluid interaction. Give him a medicine. 94 مسجلة برقم ة العامة لجمهورية مصر العربيه .What is the difference between retard and entetic coated tablets? Retard tablets : Are coated with a thin layer of different kind of coating agent which make the active constituent sustained release. Accidentally swallowed 10 tablets of aspirin and his father came to you. None of the above. Isobarmiline. 289. 299.If you have prescription containing Inderal & the patient is wheezing.Roaccutan is prescribed to patient who is women 22 years old. b. how to arrange: a.Patient take phenytoin and his hair be less growth. b.When newly married don't want children. Doctors advise. You advice him: abcd- Go to doctor. None of theabove. Type of medication. 296. no proper time) may be because the dose regimen is not easy or the dose is high or the side effects are clear.Arrange contraception.Treatment with an anti arrhythmic drug depends on the following except: abcd- Patient sex. 300. Give him another drug. This is normal side effect.Send the wife to the family doctor. 297. c.Central pharmacy only.294. c. Consult doctor.What is the meaning of poor patient compliance? The patient did not take the medication properly (no proper dose. you ask? abcd- If she is pregnant. what is your advice? 94 مسجلة برقم ة العامة لجمهورية مصر العربيه . Patient dose not take medication as the physician's advice.All of the above.Send the wife to her mother. 295. Period of medication.Contains store. Stop the drug. Give her the drug directly with no questions.Pharmacy of central hospital is: a. 298. 304.Call the doctor. what do you ask him? abcd- Which product of KCL do you need? Do you take any other antihypertensive? Do you need syrup or tablet? None of the above.Patient has hepatic disease & type II diabetics take: Rosiglitazone or piaglitazone (Avandia. = Electro Cardio Gram. 303. 301.D. b. = Twice Daily. = Glucose-6-Phosphate dehydogenase. 94 مسجلة برقم لية العامة لجمهورية مصر العربيه .Saudi national formulary. Glustin) 302. BPC 305. POM BID ECG G. Q6H = every after 6 hours. = British Pharmacopial Codex.SNF is an abbreviation for: a.6. c.What is the meaning of the following? = Prescription Only Medicine.Seasonal national formulary.Safe and nice formulary.A patient has a prescription of Enalapril + KCL.What is difference between QID & Q6H? QID = 4 times a day.P. d.d. = morning amp.s. = right ear ad lib.A. cubic centimeter Gtt or gtt = drop. or aa = of each a.m.d. = divide.or c = with cap or caps = capsule cp = chest pain D.r. = each eye. = as directed et = and ex aq. = twice daily BP = British pharmacopeia BSA = body surface area c. = give of such doses DW = distilled water D5W = dextrose% in water elix = elixir e. = in water fl or fld = fluid fl oz = fluid ounce ft = make g or GM =gram gal = gallon GI = gastrointestinal gr or gr = grain Non rep. = each ear. NS = normal saline ½ NS = half-strength normal saline O = pint o. both ears b.s. Desk Reference p..s. = ampoule ante = before aq.dc.c. compounded dil = dilute D. The following list shows the abbreviations that are not often encountered by pharnacists: comp.o.m. = at bed time IM =intramuscular Inj. both eye oz. = right eye every day o. or disc. italicization and punctuation in abbreviations. mcg or μg = microgram 94 مسجلة برقم ية العامة لجمهورية مصر العربيه .Considerable variation occurs in the use of capitalization.p. to be divided dl or dL = deciliter d.d. described as written Cc or cc. = compound.W. or o. = left eye OTC = over the counter o. drops H = hypodermic h or hr. = water a. = do not repeat NPO = nothing by mouth N.t. = dispense div..S. = as needed A.I. = discontinue disp. aa. up to a. = hour h. = ounce p. = injection IV = intervenous IVP = intervenous push IVPB = intervenous piggyback K =POTASSIUM I or L = litre Lb = pound μ = Greek mu M = mix 2 2 M or m = square meter Mcg.n.i. = by mouth Ppt = precipitated Pr = for rectum Prn or p. = left ear asa = aspirin a.C. = after meals PDR = Physicians..c.u. At pleasure freely a. = before meals ad = to.u. F. = National formulary Noct.Pt. = every q. =every day q.d. = powder Pv = vagenal use q.h. = every 4 hours 94 مسجلة برقم بالقنصلية العامة لجمهورية مصر العربيه mEq = milliequivalent mg = milligram ml or Ml = milliliter μl or μL = microlitre N & V = nausea & vomiting N. in the night 94 مسجلة برقم صلية العامة لجمهورية مصر العربيه . = night.4 hr. = pint Pulv. = every hour q.