vario MACRO CUBE. The result develop the next generation for multi element determina. a continuous progression of techno. • Desing innovations which make the instrument easy to use and maintain. detectors with expanded element capability are available logy in elemental analysis products led to the establishment for the vario MACRO cube. Consider these features: unsurpassed. Elementar is vario MACRO cube are new. Even the form and color of the of Elementar. Still at the same location today. logy has expanded the already impressive analytical range of the predecessor vario MACRO model. the world‘s leading producer of instruments for the analy- sis of C. is a system with range. N. Heraeus Micro Analyzer 1930 3 . accuracy and versatility heretofore tion on macro sized samples. • Highest precision and accuracy of the analytical results. The vario MACRO cube incorporates a century of experi- ence in elemental analysis design technique with the very Elementar has utilized its century long experience to latest electronic flow and processing technology. • Unsurpassed reliability and long time stability. • Ability to analyze nearly all types of samples. Newly developed separation techno- organic substances. • The only system for CHNS analysis in macro samples. near Frankfurt.The art of elemental analysis 100 years ago. Elementar has coupled the latest developments in micro the advanced technology company Heraeus developed electronics and mechanics with their vast experience in and manufactured the world‘s first elemental analyzer for elemental analysis. S and O. • Lowest operating and maintenance costs due to robust design and hybrid technique. Newly refined From that foundation. • No matrix dependency of the measurement. H. in the center of Germany. . the sample is transferred through the ball valve The gas mixture is separated in its components via into the combustion tube. each sample is individually flushed proven thermistors. He/Ar O2 He/Ar Ref. purge & trap chromatography. H2O and SO2 A connected PC computes the element concentration from remain in the He carrier gas stream. the detector and ensures absolutely stable pressure and flow conditions. CO2. Combustion Gas Separation Detection 5 .simply right The samples are weighed in tin or silver vessels and loaded to combust sample materials. In a fully automated process. without the need to change any a full 10 years! Oxygen is injected via a lance directly at the range or manual setting. The Elementar solid state thermistor with helium carrier gas (Heraeus patent) to remove atmo. cess. resulting in a zero blank sampling pro. hot copper (or tungsten for non sulfur modes) in the reduc- tion tube. then is detected by a thermal conductivity detector (TCD). presence of high oxygen. The TCD has a very large dynamic range which allows for Catalytic combustion is carried out at a permanent tem. hottest spot which results in optimum combustion of the combustion gases. This multi-zone tech. Note that the furnace warranty is very low concentrations. the sequential analysis of very high concentrations next to perature of up to 1200 °C. A second furnace serves for complete An electronic gas flow controller is positioned just before post combustion in CHN/CN mode. N2. the detector signal. This results in a stable instrument calibra- This is followed by reduction of the combustion gases on tion over months or even years.The instrument concept . and the sample weight on the basis of nique guarantees comple conversion even for very difficult stored calibration curves. which utilizes well While in the ball valve. in the integrated 60 position carousel. The formed analyte gases. TCDs are stable for years and are not damaged iven in the spheric nitrogen. 26%) (41.Peak graphic .85%) 8000 8000 [°C ] 260 7000 7000 240 220 6000 6000 200 180 5000 5000 160 4000 4000 140 120 3000 3000 100 80 2000 2000 60 40 1000 1000 20 0 0 0 0 100 200 300 400 500 t [s] 0 100 200 300 400 500 t [s] N C H N C H S (16.26%) TCD-Signal TCD-Signal CO2 Temp (16.68%) (18.Sulfanilamide N N C (16.26%) (41.85%) (4.26%) (41.85%) (4.62%) 8000 [°C ] 8000 [°C ] 260 260 7000 240 7000 240 220 220 6000 6000 200 200 180 180 5000 5000 160 160 4000 140 4000 140 120 120 3000 100 3000 100 80 80 2000 2000 60 60 40 40 1000 1000 20 20 0 0 0 0 0 100 200 300 400 500 t [s] 0 100 200 300 400 500 t [s] .68%) TCD-Signal H2O Temp TCD-Signal SO2 Temp (16. The method is most precise for labs which peak has passed the detector. peak overlapping and drift) are not issues for dynamic range. resulting in baseline resolu. by-passing the other two columns. technique to ensure the highest performance. CF-Hybrid technology streams only a user defined percentage of the combustion gases to the Each heating step takes place only after the subsequent reduction tube. to be analyzed even when there are large concentra- detection is crucial for the performance of the instrument. amounts of organic material. run larger batches of samples with a similar matrix. H2O and SO2 are sequentially adsorbed on specific vario MACRO cube CN Continuous Flow Hybrid for columns. the vario MACRO cube. quantified by the TCD. The Continu- diverted directly to the TCD. It is important for labs with a very high sample throughput The H2O column is then heated and the desorbed gas is to have the lowest possible cost per analysis. even for samples with very large differences in rela- tive concentration. 7 . After the detection of the N2 peak. The purge & trap chromatography approach enables large bustion and subsequent analysis of the combustion gases. CO2 is released to the TCD and detected. up to 150 mg carbon abso- The perfect separation of the analyte gases prior to the lute. Finally. Thus. With no moving parts. the CO2 column is quickly heated. CO2. N2 passes through all three columns and enters economical operation .the robust and elegant solution! the TCD. Elementar uses a well proven with excellent precision and accuracy. tion. is cube CN results in significant savings in operation reagents. tion differences between the elements.The perfect gas separation Purge&trap Chromatography with TCD: a dynamic combination Elemental analysis is based on the high temperature com. The adsorp- tion of combustion gases on three separation columns and Problems that are typical for alternative methods (matrix subsequent controlled desorption allow for a very wide dependency. the vario MACRO cube can analyze both micro and macro samples With the vario MACRO cube. This technique also results in automatic optimization of the time of analysis. the SO2 column is ous Flow Hybrid (CF-Hybrid) option for the vario MACRO heated and the gas. User Interface Instrument Software Audit Trail in accordance with 21 CFR Part 11 System Check . tors do not need special skills to take advantage of the instruments powerful capabilities. User friendliness is The basis for this is the use of the latest micro processors designed into the software at all levels. optimization as well as remote control and diagnosis over the internet. maintained internally to ensure the highest quality and performance. The vario MACRO cube‘s firmware (internal software of the analyzer) is stored on flash memories. The system is designed for intuitive operation. fast signal communication between components in the analyzer (such as the detector signal) is handled by the All Elementar instrument software is developed and fail-safe CAN bus technology. The critically important requirements of 21 CFR Part 11 data safety. tions are digitally controlled and monitored. including graphics and statistics • automatic optimization of instrument operating conditions • monitoring of maintenance intervals • integration into exisiting networks • data transfer into LIMS • data transfer to calculation programs like Excel® 9 . Our software runs under the Win- dows® operating system and offers state of the art features and capabilities: • almost unlimited storage capacity of analytical data. but con- tent sensitive help is just a click away. A commercial PC or laptop serves as the user interface for control and evaluation. which can be eas. The software is designed in accordance with the strict ily updated via PC or the internet.good instrument The cube instruments of Elementar set new standards as Self-explanatory user navigation and content-sensitive the first elemental analyzers in which all instrument func.Good software . This results in Graphical leak checking with pictorial guides for each step completely new possibilities for automatic operation and are a new favorite feature of users. Instrument opera- and electronic sensors for all gas flows and pressures. help screens make printed manuals almost obsolete. 30 13.015 ± 0.36 ± 0.05 Measurements: 5 Weight: 50 mg Flue ash 1.533 ± 0.3 ± 0.009 – – Measurements: 5 Weight: 150 mg * Element concentration in [%].78 ± 0.003 – – 12.05 4.03 Measurements: 6 Weight: 20 mg Polyethylene 84.09 – – 11.005 – – Measurements: 5 Weight: 150 mg Fish meal 42.301 ± 0.054 ± 0.723 ± 0.024 Measurements: 4 Weight: 100 mg Fertilizer 0.4 ± 0.888 ± 0.008 16.010 – – Measurements: 5 Weight: 150 mg Wheat – – – – 1.339 ± 0.41 ± 0.37 ± 0.04 – – Measurements: 4 Weight: 200 mg Starch 39.022 0.003 2. Standard deviation in [%] .108 ± 0.908 ± 0.03 – – 0.018 Measurements: 4 Weight: 40 mg Tobacco 41.13 ± 0.009 18.006 0.058 ± 0.014 0.4 ± 0.676 ± 0.008 0.84 ± 0. Carbon * Hydrogen * Nitrogen * Sulfur * Sulfanilamide 41.442 ± 0.258 ± 0.034 ± 0.03 14.01 4.61 ± 0.87 ± 0.23 ± 0.006 0.03 0.148 ± 0.06 8.006 Measurements: 4 Weight: 50 mg Coal 78.622 ± 0.28 ± 0.005 Measurements: 4 Weight: 100 mg Oil 86.48 ± 0.04 0.02 5.011 0.008 2.87 ± 0. MACRO cube’s high dynamic range electronic amplifica- able for the macro elemental analysis of CHNS (optionally tion of the detector signal as well as extremely stable gas O and Cl). Competitive analyzers have difficulty achieving complete combustion of samples which generate very large amounts of combustion gas. the vario MAX. petrochemical. and/or for very high sample An example for this versatility is the ability to analyze both weights. The vario MACRO cube uses oxygen “jet-injection” through a ceramic lance to completely com- bust this and other types of difficult samples. e. Sample weights in mental and bio materials . as well be employed. is designed for difficult to handle inhomogeneous samples. This is possible due to the high temperature digestion at a continuous high furnace temperature of up to 1200 °C. industrial. Due to intel- ligent modular design and a wide variety of options.can be readily analyzed by the the milligram range or in the macro range can be analyzed vario MACRO cube. fossil fuels. the entire range of applications . laboratory’s external requirements change. the detection of sulfur down to 10 ppm. family.g. in soil. As one example an IR photometer allows as those of the future. The instrument’s ceutical. The applications cover all organic and the majority of Thus. The vario MACRO cube is part of a family of Elementar dynamic concentration range and the ability to handle the macro scale instruments. in the same instrument run.organic. The accuracy and precision of this detector relies on the vario The vario MACRO cube is the most flexible instrument avail. Note that one member of this most difficult types of samples. as well as 1 gram of soil samples. pharma- inorganic samples of solid or liquid form.The most flexible CHNS analyzer Today’s best ensures we are ready for the future Elementar’s elemental analyzers have a very long lifetime. 11 . special detectors can vario MACRO cube is ready for your needs today. the For even lower detection limits. Element concentrations of well below 50 ppm to 100% are Instrument requirements typically change over time as the detectable with the standard detector (TCD). environ- particular strength lies in its flexibility. No other analyzer can match the vario MACRO cube with respect to detection limit. flow via the electronic mass flow controller. organic samples up to a weight of 150 mg in the CHNS mode. 0072 ± 0.006 % Measurements: 6 Weight: 7 mg Sulfur measurements IR: Soil Sulfur: 0.007 ± 0.14 ± 0.03 % Measurements: 6 Weight: 2 mg Oxygen measurements IR: Oil Oxygen: 0.0097 ± 0.11 % Measurements: 6 Weight: 55 mg Oxygen measurements TCD: Benzoic acid Oxygen: 26.01 % Measurements: 6 Weight: 0.046 ± 0.396 ± 0.2 mg Coal Chlorine: 0.0004 % Measurements: 6 Weight: 25 mg Fuel surrogate Chlorine: 1.0002 % Measurements: 5 Weight: 300 mg .Chlorine measurements: Conostan standard (1%) Chlorine: 1. Options are available for the safety of electronic data Sulfur measurement with IR photometer (21 CFR Part 11). Conversion to CO in the be directly measured by means of the soliTIC attachment.VLS is an automatic sampler which allows the efficient measure- ment of syringe injectable liquid samples. 10 ppm. with absolutely new sensor detection of HCl in the combus- ing the life of consumable reagents. OQ). combustion gases to go through the reduction tube and detector. This can be used simultaneously with CHN determination by TCD. The VLS can be swapped out for the solid sampler in just a few minutes. vario Liquid Sampler . 13 . CO is measured with standard TCD. Accessories for special applications The measurement of total organic carbon (TOC) is possible Upgrade kits for oxygen determination with the TOC option. Inorganic carbon (TIC) in solids can using high temperature pyrolysis. and allows the user to select only a portion of the for). This can be added as tion gas over a large concentration range (patent applied a kit. or with IR detection for lower detection Software for quality assurance limits.Adding value systematically Versatility makes him a winner In addition to the standard CHNS determination. To achieve a sulfur detection limit of approx. presence of carbon at high temperature. easy add-on options provide the broadest application range for the elemental analysis: vario MACRO CN Continuous Flow Hybrid Option Accessory for chlorine analysis results in the lowest cost of analysis by greatly increas. analytical quality assurance (AQS) and instrument validation (IQ. (for fertilizer. CNS. AOAC 992. analysis mode and options 14 .2% rel.15. in accordance with the safety standards: CE-label. DIN/ISO 13878 (soil). Separation of the analysis gases by purge & trap chromatography at up to 3 specific columns and detection at TCD (IR or chemosensor optional).13. cereals. ISO 15178:2000(E) Soil quality . DIN 51724-3 (testing solid fuels . ASTM 5291-91 (CHN in oil products and lubricants). (CHN in coal and coke). oil seed. meat. CN. meat products. Operating modes: CHNS. DIN 10467 (milk and dairy products). EN 61010–1.determination of total sulfur in dry combustion Detection range*: C: 0-150 mg (or 100%) O: 0-6 mg* N: 0-100 mg (or 100%) Cl: 0-4 mg H: 0-15 mg (or 100%) S: 0-18 mg (or 100%) Detection limit*: CN with TCD: < 50 ppm (for 300 mg soil sample) S with IR: < 10 ppm (for 300 mg soil sample) Standard deviation*: < 0. S as standard with TCD. EMV low voltage directives 73/23/EEC in accordance with: AOAC 990.23. AOAC 993. depending on mode S with IR detection optional. MEBAK (breweries). AACC. LUFA. AOAC 992. Cl with chemosensor detection optional. O with TCD or IR detection optional.06. 1800°C is temporarily reached). ASBC. (100 mg glutamic acid) * depending on sample kind. flour. AOAC 968. ASTM D5373-93.Specifications vario MACRO cube Analysis method: High temperature combustion or pyrolysis of the sample and conversion of the elements into gaseous products. feed). CHN. Digestion temperatures: adjustable up to 1200°C (by combustion of the tin vessels a temperature of approx. N.determination of the sulfur content.03. regression linear to the 4th order.995% purity 7 l/analysis O2 : 99. 1. All instrument functions are digitally controllable.05 l/analysis Ar: alternative carrier gas Instrument control: Operation and control via PC under Windows®. analysis mode and options 15 .g. In full compliance with 21 CFR Part 11 (option). monitoring of the maintenance cycles. Sample weight*: up to 200 mg organic substance or up to 1. Integration in data networks like LIMS and the possibility of remote control and diagnosis via the internet. stable over months. 65 kg * depending on sample kind. extensive error diagnosis. g. Analysis time*: self-optimizing depending on element content and sample weight e.5 g soil sample.Specifications vario MACRO cube Calibration: Multi point calibration. graphics. the comprehensive ope- ration software includes e.995% purity 0. Electrical connections: 100/110/200/230 V.8 kW Dimensions: 48 × 55 × 55 cm (W × D × H) Weight: approx. statistical evaluation and almost unlimited memory capacity for analysis data incl. sleep-/wake up function. N 4-5 min (150 mg wheat) CHN 7-8 min (100 mg flue ash) CHNS 10-12 min (40 mg sulfanilic acid)) Autosampler: 60 positions in a magazine as standard reloadable any time during operation 80 or 120 positions for smaller sample sizes optional manual or automatic injection of liquid or gaseous samples optional Gases: He: 99. automatic leak test. 50/60 Hz. pharmaceuticals.elementar. oil products. etc. glue. compost. oxygen determination. Agriculture and Environment Plants. building materials. cosmetics. Industrial quality control Rubber. catalysts. Number. S and O and Cl. N. etc. waste. petrochemical products. Fossile fuels and power generation Coal.de fax: +49 (0) 6181/9100-10 . Germany web: www.de phone: +49 (0) 6181/9100-0 Donaustr. food. sewage sludge.00-5204 Elementar Analysensysteme GmbH mail: info@elementar. polymers. residual waste Special applications Chlorine determination. fertilizers. combination and occurance of the analyzed elements as well as precision of their determination by using most modern technologies represent the most advanced state of instrumental analysis for application areas like: Chemistry and Pharmaceutics Fine chemicals. filter samples 20.vario MACRO cube is the most flexible instrument for the macro elemental analysis of C. coke. H. 7 63452 Hanau. dyestuffs. etc. soil.