SCHEME OF EXAMINATION & SYLLABIBIOTECHNOLOGY ENGINEERING B. Tech. Degree Course of C A L IC U T U N IV E R S IT Y 2004 A D M IS S IO N O N W A R D S 2 COMBINED FIRST AND SECOND SEMESTER Code EN04 101 Subject Hours/Week L T P/D Session Uni./Exam Marks Hrs Marks . Engineering Mathematics I EN04 102 Engineering Mathematics 11 EN04 103 A(P) Engineering Physics(A) EN04 103 A Physics Lab(A) 103A(P) EN04 104A Engineering Chemistry(A) EN04104A(P) EN04 105 EN04 106A EN04 107A EC04 108 EC04 109 3 3 2 2 2 1 2 2 2 19 1 1 1 1 3 3 2 10 50 50 50 25 50 25 50 50 50 50 50 50 50 600 3 3 3 3 3 3 3 3 3 - 100 100 100 100 100 100 100 100 100 900 Chemistry Lab(A) Humanities Engineering Graphics(A) Engineering Mechanics(A) Basic Electronics Basic Electrical Engineering EC04 110(P) Mechanical Workshop EC04 111P) Electrical and Electronics Workshop TOTAL Note : Details of Common Course SL SUBJECT NO. CODE 1 EN04-10I 2 ENO4-102 3 NAME OF SUBJECT MATHEMATICS-1 MATHEMATICS-II ENGINEERING PHYSICS(A) PHYSICS LAB(A) ENGINEERING PHYSICS(B) PHYSICS LAB(B) ENGINEERING CHEMISTRY(A) CHEMISTRY LAB(A) ENGINEERING CHEMISTRY(B) CHEMISTRY LAB(B) ENGINEERING CHEM1STRY(C) CHEMISTRY LAB(C) HUMANITIES ENGINEERING GRAPHICS(A) ENGINEERING GRAPHICS(B) ENGINEERING MECHANICS(A) ENGINEERING MECHANICS(B) BASIC ELECTRONICS COMPUTER PROGRAMMING IN C BASIC ELECTRICAL ENGINEERING BASIC ELECTRICAL ENGINEERING CIVIL AND MECHANICAL WORKSHOP MECHANICAL WORKSHOP ELECTRICAL AND ELECTRONICS WORKSHOP COMMON FOR COMMON FOR ALL. COMMON FOR ALL. AI,EE,EC,1C,BM,BT CH,CE,ME,PE CH,CE.ME,PE AI,CS,EE,EC,IT,IC,BM,BT,PT AI,EE,BC,IC,BM,BT CE,ME,PE CE,ME,PE CH CH COMMON FOR ALL AI,CS,EE,IT,IC,PT,BM,BT CE,CH,ME,PE AI,CH,CS,EE,EC,IT,IC,BM,BT,PT CE,ME,PE EC,BM,BT,AI,IC CS, IT, PT AI,EE,EC,IC,BM,BT, CS,IT.PT EE,CS,IT,PT EC,A1,BT,BM,IC EE,EC,AI,BT,BM,CS, IT,IC,PT Al, S,EE,EC, IT,IC,BM,BT, PT 4 ENO4-103A ENO4-103A(P) ENO4-103B EN04-103B(P) EN04-104A EN04-104A(P) EN04-104B EN04-104B(P} ENO4-104C EN04-104C(P) EN04-105 EN04-106A EN04-106B EN04-107A EN04-107B EC04-108 CS04-108 EE04-I09 CS04-109 EE04-110(P) EC04-110(P) EEO4-111(P) 5 6 7 8 9 10 11 3 THIRD SEMESTER Code EN04 301A BT04 302 BT04 303 BT04 304 BT04 305 BT04 306 BT04 307(P) BT04 308(P) Subject ENGINEERING MATHEMATICS-III COMPUTER PROGRAMMING IN C CELL BIOLOGY CHEMICAL ENGINEERING I MICROBIOLOGY BIOCHEMISTRY I MICROBIOLOGY LAB BIOCHEMISTRY LAB Hours/Week Session University Marks Exam L T P/D Hrs Marks 3 2 3 3 3 3 - 1 1 1 1 1 - 2 3 3 50 50 50 50 50 50 50 50 3 3 3 3 3 3 3 3 100 100 100 100 100 100 100 100 TOTAL 17 5 8 400 - 800 FOURTH SEMESTER Code EN04 401A EN04 402 BT04 403 BT04 404 BT04 405 BT04 406 BT04 407(P) BT04 408(P) Subject ENGINEERING MATHEMATICS - IV ENVIRONMENTAL STUDIES BIOCHEMISTRY II CHEMICAL ENGINEERING II BIOPROCESS PRINCIPLES ANALYTICAL TECHNIQUES IN BIOTECHNOLOGY CHEMICAL ENGINEERING LAB I BIO-ANALYTICAL TECHNIQUES LAB Hours/Week Session L T P/D Marks University Exam Hrs Marks 3 3 3 3 3 3 - 1 1 1 1 1 1 - 3 3 50 50 50 50 50 50 50 50 3 3 3 3 3 3 3 3 100 100 100 100 100 100 100 100 TOTAL 18 6 6 400 - 800 FIFTH SEMESTER Code Subject Hours/Week Session L T P/D Marks University Exam Hrs Marks BT04 501 BT04 502 BT04 503 BT04 504 BT04 505 BT04 506 Industrial Biotechnology Mass Transfer and Separation Process Molecular Biology Enzyme Engineering & Technology Chemical Reaction Engineering Applied Electronics 3 3 3 3 3 3 - 1 1 1 1 1 1 - 3 3 50 50 50 50 50 50 50 50 3 3 3 3 3 3 3 3 100 100 100 100 100 100 100 100 BT04 507(P) Chemical Engineering Lab II BT04 508(P) Molecular Biology Lab TOTAL 18 6 6 400 - 800 4 SIXTH SEMESTER Code BT04 601 BT04 602 BT04 603 BT04 604 BT04 605 BT04 606 BT04 607(P) BT04 608(P) Subject Engineering Economics & Principles of Management Instrumentation and Process Control Bio-Process Engineering Genetic Engineering Protein Engineering Bioinformatics Hours/Week Session University Marks Exam L T P/D Hrs Marks 3 3 3 3 3 3 - 1 1 1 1 1 1 - 3 3 50 50 50 50 50 50 50 50 3 3 3 3 3 3 3 - 100 100 100 100 100 100 100 - Bio Process Technology Lab I Mini Project TOTAL 18 6 6 400 - 700 SEVENTH SEMESTER Code BT04 701 BT04 702 BT04 703 BT04 704 Subject Downstream Processing Bioprocess Plant Design Recombinant DNA Technology Hours/Week Session University Marks Exam L T P/D Hrs Marks 3 3 3 3 3 - 1 1 1 1 1 - 3 4 3 50 50 50 50 50 50 50 50 3 3 3 3 3 3 - 100 100 100 100 100 100 - Environmental Biotechnology BT04 705 Elective I BT04 706(P) Bio Process Technology Lab II BM04 707(P) BM04 708(P) Seminar Project Work TOTAL 15 5 10 400 - 600 ELECTIVE – 1 A Software Engineering B Chemical Engineering Thermodynamics C Food Biotechnology D Operation Research E Plant Biotechnology and Tissue Culture. . 5 EIGHTH SEMESTER Code Subject Hours/Week L T P/D Session Marks University Exam Hrs Marks BT04 801 BT04 802 BT04 803 BT04 804 BT04 805 BT04 806 BT04 808(P) BT04 808(P) Immunology & Immuno Technology Bioethics and Intellectual Property Rights Metabolic Engineering Elective-II Elective-III Immunology & Genetic Engineering Lab Project Work Viva Voce TOTAL 3 3 3 3 3 - 1 1 1 1 1 - 3 7 - 50 50 50 50 50 50 50 - 3 3 3 3 3 3 3 - 100 100 100 100 100 100 100 100 15 6 6 400 - 700 AGGREGATE FOR EIGHT SEMESTERS : 5300 ELECTIVE – II A B C D E Genomics & Proteomics Molecular Modelling & Drug Design Design of Process Equipments Safety in Process Plants Hazardous Waste management. 8300 3000 ELECTIVE – II A B C D E Bio Pharmaceutical Technology Animal Biotechnology Project Management Transport Phenomena Material Science and Technology. . 2 questions A and B of 15 marks from module II with choice to answer any one QIV.Assignments/Term project/any other mode decided by the teacher.root test .Gauss' elimination -homogeneous linear equations fundamental system of solutions .Euler formulae .absolute convergence . 2. 1 and2..S.8 short type questions of 5 marks.L' hospital's rule . Internal work assessment 60 % . Advanced Engineeing Mathematics(second edition). Reference books 1. Sastry. Prentice Hal! of India..centre of curvature -evolute unctions of more than one variable . McGraw Hill 6. and L.. S. Kreyszig E.Jacobians .2 questions A and B of 15 marks from module III with choice to answer any one QV .trigonometric series .interval of convergence Taylors and Maclaurins series expansion of functions .Cayley-Hamilton theorem .R.idea of partial differentiation .consistency of linear equations .system of linear equations . skewHermitian and unitary matrices.functions having arbitrary period .101: MATHEMATICS I (Common for all B.numerical method for determining Fourier coefficients . Engineering Mathematics-Vol. Advanced Engineering Mathematics.series of positive and negative terms . . Advanced Engineering Mathematics. programmes) 3 hours lecture per week Module I: Differential Calculus (15 hours) Indeterminate forms .Test papers ( minimum 2) 30 % .definite.use of Leibnitz formula in the Taylor and Maclaurin expansions Module III: Matrices (21 hours) Rank of a matrix . Schaum's Outline Series.2 questions A and B of I5 marks from module IV with choice to answer anyone.even and odd functions .reduction of a matrix to echelon and normal forms .harmonic analysis.ratio test .Raabe's test .Euler's theorem for homogeneous functions .Diagonalisation of a matrix using Eigen values and Eigen vectors. Greenberg. . Ayres F. Tech.2 questions A and B of l5 marks from module I with choice to answer any one QIII.Other measures like Regularity and Participation in Class.Fourier series . Differential and Integral calculus. Wylie C..Pearson Education Asia. PiskunovN. Barrent.. Matrices. Michael D. MIR Publishers 5. Module IV: Fourier series and harmonic analysis (15 hours) Periodic functions .C.half range expansions -approximation by trigonometric polynomials .matrix associated with a quadratic form. 10 % .Eigen values of Hermitian. 2 from each module QII .quadratic forms.Leibnitz formula for the nth derivative of the product of two functions .maxima and minima of functions of two method of Lagrange multipliers.solution of a system of equations using matrix inversion Eigen values and eigen vectors .applications in errors and approximations .change of variables . McGraw Hill 3.comparison test .test for alternating series . Wiley Eastern 4.minimum square error . Module II: Infinite Series (15 hours) Notion of convergence and divergence of infinite series . Total marks = 50 University examination pattern QI . semidefmite and indefinite forms.power series .chain rule of partial differentiation .6 EN04.radius of curvature . programmes) 3 hours lecture per week Module I: Ordinary differential equations (21 hours) Equations of first order ..2 questions A and B of 15 marks from module II with choice to answer any one QIV .Other measures like Regularity and Participation in Class. McGraw Hill 3.Test papers (minimum 2) 30 % .transform of periodic functions .Gauss' divergence theorem . Advanced Engineering Mathematics. Piskunov N. Module II: Laplace transforms (15 hours) Gamma and Beta functions . Greenberg. Matrices.1 and2.2 questions A and B of 15 marks from module IV with choice to answer any one. MIR Publishers 5. homogeneous and linear types . Module III: Vector differential calculus (15 hours) Vector function of single variable .2 questions A and B of l5 marks from module I with choice to answer any one QIII. 10 % . including problems in mechanical vibrations. Wiley Eastern 4.transforms of unit step function and impulse function . Pearson Education Asia. and L. Module IV: Vector integral calculus (15 hours) Double and triple integrals and their evaluation . Prentice Hall of India Internal work assessment 60 % . Ayres F. University examination pattern QI . S. QII . 2. Michael D.divergence and curl of vector fields .method of variation of parameters -Cauchy's equation .C. Differential and Integral calculus.separable. Tech. Barrent.exact equations .2 questions A and B of 15 marks from module III with choice to answer any one Q V .line.8 short type questions of 5 marks.differentiation of vector functions – scalar and vector fields gradient of a scalar field .simple applications of differential equations in engineering problems. Advanced Engineering Mathematics(second edition).. Total marks = 50.Stokes' theorem (proofs of these theorems not expected) line integrals independent of the path.R. Advanced Engineering Mathematics. .S.orthogonal trajectories .. McGraw Hill 6. electric circuits and bending of beams.definitions and simple properties . Sastry. Engineering Mathematics-Vol. Kreyszig E. Wylie C.linear second order equations -homogeneous linear equation of the second order with constant coefficients -fundamental system of solutions -Solutions of the general linear equations of second order with constant coefficients. Schaum's Outline Series.their physical meanings relations between the vector differential operators.Green's theorem .7 EN04 -102: MATHEMATICS II (Common for all B..Laplace transform -shifting theorems-Transforms of derivatives and integrals differentiation and integration of transforms . surface and volume integrals .Laplace transform -inverse transform .Assignments/Term project/any other mode decided by the teacher.solution of ordinary differential equations using Laplace transforms. Reference books 1.. 2 from each module. flux quantisation). Josephon's effect.Basic concepts and properties of laserSpontaneous and stimulated emission. IT.characteristics of a transistor in common emitter configuration-Input.Laurent's half shade polarimeterApplications of polarised light. solar cell. Meisnner effect.8 EN04.Avalanche and zener breakdown.Types of super conductors.fibre. EE.Helium and Neon and semiconductor lasers-Applicattion of lasers.Air wedge.Fermi level in intrinsic semiconductor. Laser physics.Classification of solids on the basis of energy band gap-Intrinsic and extrinsic semiconductors-Elemental and compound Semiconductors. Application of semi conductors. Hall effect in semiconductors.Double refraction. Diffration of light-Introduction of Fresnel and Fraunhoffer class of diffraction and their distinction.Measurement of wavelength and refractive index.Fibre optics. resolution of spectral lines and refractive index of gases. IC.Testing of optical planeness of surfaces. CS.Step index single mode and multi mode.Diffusion and total current.optic fibre communication (block diagram) and it's advantages-Applications of optic fibres.103A: ENGINEERING PHYSICS(A) (common for AI.Expression for ratio of their coefficients-Absorption. critical current.Resolving power and dispersive power of grating. liquid crystal display(LCD) and zener diode.Applications of super conductivity. PT) 2 hours lecture per week Module I (11 hours) Semi conductor Physics. EC. output resistance and current amplification factor.Application of zener diode as a voltage regulator.Rayleigh's criteria.Graded index fibre-Numerical aperature and acceptance angleSignal distortion in optical fibres and transmission losses( brief ideas only).Electron and hole concentrations in intrinsic semi conductor in thermal equilibrium.BCS theory of super conductivity (qualitative) . Interferometry.Michelson's interferometer-Types of fringes-Visibility of fringes-Application of Michelson's interferometer in determination of wavelength of monochromatic light.Newton's rings. photo diode.Fraunhoffer diffraction -Simple theory of diffraction grating.Light emitting diode.SQUID .c. Module III (11 hours). their production and detectionRotatory polarisation.BT.Thin wedge shaped film. Module II (11 hours) Interference of light.Theory of d. photo resistor (LDR).Interference from plane parallel thin films.population inversion and optical pumping-Construction and components of a laser-Ruby.Band model of p-n junction.Interference due to division of amplitude.Junction diode and its characteristics.Colours of thin films in reflected and transmitted light.Laurent's half shade (brief explanation).Josephon's effect.Huygen's explanation of double refraction in uniaxial crystals-Positive and negative crystals.Electrical conductivity of extrinsic semi conductor. Poarisation of light. for resolution of spectral lines. its construction and working. Basic principle of holography and its application. BM.photo transistor. construction and working -Quarter and half wave plates.Law of mass action-Electrical conductivity of intrinsic semiconductor.Nicol prism.Basic principle -fibre dimensions and construction.Derivation of Hall coefficientDetermination of Hall coefficient by measuring Hall voltage-Applications of Hall effect Super conductivity-Properties of superconductors (critical magnetic field.Theory of circularly and elliptically polarised light.Formation of energy bands in solids. .Fresnels diffraction and rectilinear propogation of light-Diffraction pattern due to straight edg and expression for intensity maximum and minimum.Fermi level in n-type and p-type semiconductors. Brijlal and Subrahmanyam N.8 short type questions of 5 marks.Ultrasonic diffractometer and determination of velocity of ultrasonics in a liquid.Ultrasonics. Introduction to semi conductor materials and devices.2 questions A and B of l5 marks from module I with choice to answer any one QIII. University examination pattern QI .2 questions A and B of 15 marks from module IV with choice to answer any one .S. John Wiley and Sons 2.Wein's displacement law.9 Module IV (11 hours). Tyagi. John Senior.. G Aruldhas Quantum mechanics Prentice Hall of India 5.Detection of ultrasonics .Perfect black body. Chand 3.electric effect.L. Intoduction to classical and modern optics.Chand and Co 6.Expectation values-ApplicationsParticle in a box (motion in one dimension).Distinction between Newtonian and quantum mechanics.Assignments/Term project/any other mode decided by the teacher. S. Murukesan R. S. Physics for Engineers. Total marks = 50. S.Distribution energy in the spectrum of a black body. Kale Gokhale. Vasudeva A.Schroedinger wave equation for free particle -Potential in schrodinger equation -Time dependant and time independent schroedinger equations and their derivations.Nath. Fibre optic communiction 4. V. New Age International 2.Test papers (minimum 2) 30 % .R.S. Quantum mechanics. Gupta S. Chand 7. Fundamentals of Solid State Electronics. Internal work assessment 60 % .Absorbing power.2 questions A and B of 15 marks from module III with choice to answer any one QV . Solid state physics. 2 from each module QII . New Age International Reference books 1.Other measures like Regularity and Participation in Class. Modern Engineering Physics. Pillai.Planck's hypothesis-Derivation of Planck's law of radiation. Solid State Physics. 10 % .O.Piezo .Piezo electric crystal. Text book of Optics. Sreenivasan M . M. Modern Physics —S. and Kumar. K. Arendt 3. Kitab Mahal 8. Text books 1.General properties and applications of ulltrasonics .Production of ultrasonics by piezo-electric oscillater. Planck's quantum theory. Mayer.2 questions A and B of l5 marks from module II with choice to answer any one QIV . reflecting power and transmitting power of a body or surface. 13.Dani. 12. Wave length of a monochromatic light by straight edge using laser beam. 6. resolution of spectral lines and refractive index of a gas. 21.and wave length of emitted radiation 5. Divergence of laser beams using He-Ne laser or diode laser. Voltage regulation using Zener diode 8. Avadhanulu.S. 18.EE. IC. Resolving and dispersive power of a grating . A. and R. 16. 15.BM) 1 hour lab per week or 2 hours lab per alternate weeks 1.Guptha and Dr. Frequency of an electrically maintained tuning fork(transverse and longitudinal mode) Wave length and velocity of ultrasonic waves using ultrasonic difractometer. fibre.M. Wave length of laser using transmission grating. 22. Michelson's interferometer. 10. Band gap energy in a semi conductor using a reverse biased p-n junction. Measurement of numerical aperature .Publishers. 19. Static characteristcs of a transistor (p-n-p or n-p-n )in common emitter configuration 3.Pragati Prakashan.A. EC.N.Dr. 17. Wavelength of mercury spectral lines using diffraction grating and spectrometer.L. "Practical Physics with viva voice". Characterisitc of a photo diode. Characteristic of a photo resistor (LDR) 7. Chand.10 EN04-I03A(P): PHYSICS LAB(A) (Common for AI. S. 11. Specific rotatory power of cane sugar solution using polarimeter. acceptance angle and attenuation in an optical Measurement of displacements using optic fibre.M. 20. 2. Wave length of sodium light by Newton's rings method. 24. Diameter of a thin wire or thickness of a thin paper by air wedge method. (Any 12 experiments should be done) Reference Books:1. 14. Planck's constant using photo-electric cell or solar cell Hall coefficient by measuring Hall voltage in a semi conductor.Pokley. Characteristics of a Zener diode 4. Refractive indices of ordinary and extra ordinary rays in calcite or m quarts prisms. Internal work assessment Lab practicals and record Test/s = 15 = 10 .determination of wavelength of a monochromatic source. 9. 2.V KumarPublishers. 23. Characterisitics of a LED. Characterics of a solar cell. " Experiments in Engineering Physics". dislocations.Introduction to Nano Science -Carbon nano tubes and nanowires Applications with (l Hour) Non-crystalline state . Lee (1996) "Concise Inorganic Chemistry" Chapman and Hall Ltd.Internal structure .Elements of symmetry .Braggs equation (derivation) single crystal and powder method -(Debye-Scherrer Camera) Cubic systems structure elucidation -d100: d110: d111 ratio (problems to be worked out) . BT.(Covalent solids .Chemical Properties-thermotropic-lyotropic-epitaxial. IT.) (1 Hour) Crystalline state: Steno's law .Fermi level -Applications of conductors-(transmission lines-OFHC Copper.conducting glasses .Resistivity -(Free electron theoryexplanation with Fermi . .crystal imperfections(point-line-surface-volume -burgers vector.Space lattices -Crystallographic axes. pp1032 2. bonding characteristics and Structure relation of.Super cooled liquids .tetrahedral and octahedral voids-Alloys . D. Glasstone {1997) "Textbook of Physical Chemistry" Macmiilan. pp1000. Atkins and J.(applications. EC. IC. Depaula (2001)" Physical Chemistry" W...glass .(ABCABC. (l Hour) Liquid crystals. EE.liquid crystals.(Glass) . W.properties .(KCN) .heating elements-Resistance thermometers).R Freeman and Co.growth-Freedericksz transition-applications -Liquid crystal thermometers. BM. CS. Atkins (1987) "Physical Chemistry" Oxford University Press.Ionic solids metals) .11 Total marks = 25 EN04-104A: ENGINEERING CHEMISTRY(A) (Common for AI.edge and screw) Physical properties.(ABAB) . Precision resistors. P.Optical fibre. PT) hours lecture per week SECTION-1 CHEMISTRY OF ENGINEERING MATERIALS: Module 1(13 Hours) Solids: Classification of solids with examples. S. W.Hume Rothery rule-Conductivity . ACSR..Piezoelectricity examples. J.Polycrystalline -Amorphous Partially melted solids . New Delhi.Characterization.X-ray study.).Super Conductors (type I and II-examples) (5 Hours) Semi conductors . 4.LCD displays (3 Hours) Reference books 1. Oxford.(Crystalline .Ferro-electricity . pp-857. Contact materials.metallic bonding. P.Stacking of atoms. London.Band theory-(MOT) Valence band-Conduction band-intrinsic and extrinsic semiconductors-Fabrication of semiconductor materials-Crystal Growth-ultra pure Silicon production-zone refining-Fabrication of Integrated Circuits (IC) (2 Hours) Dielectric materials-Polarization .Nematic phases-Smectic Phases-Cholesteric PhasesColumnar Phases. pp-1320 3.Law of rational indices-Crystal systems .Diracstatistics).solid supported liquids (stationary phases in reverse phase chromatography) . mechanisms of lubrication -Fluid film or hydrodynamic.wt. Module 2 (13 Hours) High Polymers and Lubricants. Organo phosphates. PVC. Foaming. Thermoplastic resins (Acrylonitrile. Hexanol. Film casting. Cellulose fibres. J.PVC. Axle grease) Solid lubricants (Graphite. pp-856. W. L. pigments. Raghavan (2000) "Material Science and Engineering-A First Course" Fourth edition. Silicones). Li-soap grease. Addison-Wesley. K.12 V.pp-304.10.Wt of Polymers-Number average Molecular wt.l. Strength. London pp-598. Compression. W. PAN-Co-poly vinyl Chloride). anionic.Structure relation to lubrication property) and synthetic lubricants (Di-basic acid esters. Poly glycol ethers.Klaubunde (2001) ''Nano scale Materials in Chemistry" Wiley-Interscience.Co-polyvinylacetate. Tricresyl phosphates. extreme pressure lubrication. 8. J.Natta Polymerization)-Electrochemical Polymerization-Metathetical Polymerization-Group transfer Polymerization (3 Hours) Mechanism of polymerization (Cationic. K. Amine phosphates. and free radical). KoIasinski (2002) "Surface Science: Foundations of Catalysis and Nano science" John-Wiley and Sons. Extensibility. PMMA. thin film or boundary lubrication. Van Vlack (1998) "Elements of Materials Science and Engineering" Sixth edition. Solution polymerization. antioxidants. Molybdenum di-sulphide.-Fibres (Nylon6. Solid and Gas Phase Polymerization (2 Hours) Structure relation to properties(Chemical resistance. pp-400. Plastic deformation. Fibres and liquid resins) Polymerization (Chain polymerization Polythene. Organo-metallics. Weight average Mol. Silicon polymers) .Classification of Polymers-(Natural and Synthetic. pp-485.Classification of Lubricants(Liquid(animaI and vegetable oils. 9. W. lubricants. Ltd. New Delhi. Reinforcing) (1 Hour) Lubricants: Theory of friction . Silicone rubber) (3 Hours) Compounding of Plastics (Fillers. J. 5.Teflon -polystyrene -polymethylmethacrylate) Condensation1 polymerization(Polyamide and Polyesters) Copolymerization (Buna-S. Crystallinity) -Mol. Prentice-Hall of India Pvt. Die Casting.Semi-solid (Ca-soap grease. Aniline point). Thermoplasic and Thermosetting.H.Goodby (1997) "Chemistry of liquid crystals" VCH Publishing. Organic and Inorganic. Petroleum oiIs). Interfacial condensation. Calcium sulphonates. Corrosion stability. Phenols. Organo silicones)). ElastomersNatural rubber-Structure.Gel Permeation Chromatography (1 Hour) Thermosetting resins (Bakelite. 6. PVA . Emulsification. Plastics. Sulphurised fats. Suspension polymerization. Buna-N. PE). Melt polycondensation. Cloud point and pour point.Polymerization techniques( Bulk polymerization. injection. Buna-N. pp-326. Extrusion and Blow moulding. Elastomers. Urea-Formaldehyde. PVC. 10.Smith (2001)" The Physics and Chemistry of Materials" WileyInterscience. Nylon66. Properties of Lubricants (Viscosity index. Al-soap grease. Plasticizers.Gersten and F. 7. Stabilizers) and Fabrication (Calendering. dacron.PS. Thermoforming.Coordination polymerization (Ziegler. Additives and their functions (Fatty acids. Solution polycondensation. flash point and fire point.Vulcanization-Synthetic rubbers (Neoprene. thiokol. Kevlar) Application of polymers in electronic and electrical industry. Emulsion polymerization. NyIon 6. Buna-S. digital method electrochemical series .concept of pH .Henderson's equation for calculation of pH. . Ni/Cd.Poggendorf's compensation method.Classification of pollutants (Global. pp-1206. Regional.Impressed current.al (2002) "Polymer Science" New Age International pp-505 2.lead acid. B.Automobile exhausts . pp-857.W. Nickel). CFC. NOx.Gowarikeret. Pollutants .R. (5 Hours) Acid. A+2.theory . pp1320. Pt|CL| Cl-.Definitions .W Atkins(1987)"Physical Chemistry” Oxford University Press. M|A+.Eg: CO2.Othmr Encyclopedia of Chemical Technology " Vol.A. and Precipitation) Buffer solutions . Hydrocarbon/air fuel cell-Bio-chemical fuel Cell. SECTION – 2 CHEMISTRY OF MATERIAL AND ENVIRONMENTAL DAMAGE Module . Pt|H21H+. Standen (Ed)(1964) "Kirk .Nernst equation. Module .4 (9 Hours) Material damages and prevention: Corrosion . pp-925. New Delhi. Oxidation-reduction.Galvanic corrosion-(corrosion at contact points in computers-Ag/Au)-Inter granular corrosion (18-8 Steel). Oxford.Polarographystorage cells . (4 Hours) Reference books 1 S.Bases .effects on environments -Air pollution – Fossil fuel burning .13 (3 Hours) Reference books 1.Glasstone(1997) “Text book of Physical Chemistry” Macmillan.types of electrodes (M|M+. Hampel(Ed)(1964)'Encyclopedia of Electrochemistry" Reinhold Publishing Corpcenration. M|MA|A-. (4 Hours) Environmental damages and prevention: Pollution . 3 C. SPM. Wire-gun method)-Tinning. Academic Press. 4 A. PBN formation-chemical equations required) - .pH measurement.H 2/O2 fuel cells(Bacon cell).al (1964)" Modem Materials-advances in development and application" Vol 17.Fuel cells . SOx.3 (9 Hours) Electrochemistry: Single Electrode potential (theory . Pt|02|OH" -glass electrode) Electrochemical cells-concentration cells-Salt bridge .Types of corrosion .Protection by Sacrificial Anode. Anodization of AluminiumPassivation of metals by chemical treatment. New York.Dissociation constants-Potentiometric titrations(Neutralization.Gonser et.emf measurement .Photochemical smog .application in corrosion control .theoretical aspects -(electrochemical theory) .(instrumental details required) .Liquid junction potential. 2 P.ElectropIating-(Chromium. 3 John Wiley and Sons.PAN. POP. lnc. Local.Microbial corrosion-Factors influencing corrosion.CoatingsOrganic-(paints and polymers )-Inorganic Coatings-Galvanizing (dip coating. Sherardizing. New York. Dissolved metals) .Galvanic series -Pourbiax diagram assessment of corrosion potential of materials . basic condition (Corrosion in boilers) . B.examples) . derivation from thermodynamic principles) . Persistent and Non-persistent. Corrosion protection-Self protecting corrosion products-Pilling-Bedworth rule. New York. VOC. CO.(Lowry-Bronsted and Lewis concepts .over voltage .Dry corrosion-direct chemical -Wet Corrosion-Electrochemical-differential aeration -Corrosion of Iron in acidic neutral. fly ash . C. 8. "Environmental Chemistry Newage International Pvt.hazardous waste . 3. 10 % . A. Rowe and G. Chobangoglus(1985) “Environmental Engineering” MaGraw Hill International.CFC dissociation and its reaction with Ozone -Alternate refrigerants — Monitoring of pollution . V Raghavan (2000) 'Material Science and Engineering – A First Course “PrenticeHall of India Pvt. New Delhi – pp-273.Soil pollution-Solid waste-radio nuclides-Toxic metals.2 questions A and B of 15 marks from module IV with choice to answer any one . Peavy. University examination pattern QI .. 2 from each module QII . Water pollution.Bag filters. 5.CFCs -Nomenclature CFCs -Chapman cycle of Ozone formation.monitoring and.8 short type questions of 5 marks. pp-720.deep-well injection (5 Hours) Reference books 1.14 Stratospheric Ozone depletion.gases (CO. NOs. L.Pollutant Classification-(Organic.Thermal pollution.Coal composition. 6. Internal work assessment 60 % . Ltd. Scrubbing. Anaerobic-USAB process-Industrial waste water treatment. L L Shreir (Ed) ''Coirosion Control” Vol 1 and II Newnes-Butterworths. pp-485. Total marks = 50.Other measures like Regularity and Participation in Class. S. S P Mahajan (1985) “Pollution Control in Process Industries " Tata McGraw Hill. New Delhi pp-364. Suspended and Dissolved.T. New Delhi. pp-532.Toxic metal waste. SO2.2 questions A and B of 15 marks from module III with choice to answer any one QV . Manahan (1975) “Environmental Chemistry” Willard Grant Press Boston.2 questions A and B of l5 marks from module II with choice to answer any one QIV . Methods of control of Air pollution . controlIncineration-Dioxins. Inorganic. Ltd. pp-1206. New Delhi – pp-530. cyclones. K. Catalytic converters -composition and action with CO. R. 7. S. London. 5 C. De (I996).Assignments/Term project/any other mode decided by the teacher. ESP. Harnpel (Ed) "Encyclopedia of Electrochemistry' Reinhold Publishing corporation.BOD-COD-) monitoring (analytical methods-brief discussion) and control -Waste water treatment-Aerobic.2 questions A and B of l5 marks from module I with choice to answer any one QIII. McCarty (1986) “Chemistry for Environmental Engineering” McGraw Hill Book Company. D. 4. Sawyer and P. E.Test papers (minimum 2) 30 % .N. A. 2.NOX )and paniculate (High volume sampler) -Pollution from thermal power plants .. H. 4. 7. 13. Electrodepostion-plating of Copper-detection of the thickness of the layer deposited. . 8. Solution. (Atleast 12 experiments should be done) 17. EC. PET. Measurement of Single Electrode potential-Poggendorf s method (M|M+. M|MA| A-. H2. Salt bridge preparation. Estimation of Dissolved oxygen (Winklers method) 16. Al. EE. Identification tests for certain common plastics (PE. IC. Calculation of concentration in ppm and microgram per M3 and comparison ofdatawith permitted levels. BT) 1 hour lab per week or 2 hours lab per alternate weeks List of Experiments 1. results of each experiment and punctuality in the submission of Rough and Fair Records) Test/s = 10 Total Marks = 25. Monel metal or any alloys of industrial use ) Potentiodynamic and Potentiostatic methods. Preparation of some liquid crystals and study of their properties. Flash and fire point-Pensky--Martens apparatus. pHmeter-Calibration and measurement of pH-Preparation of pH by Henderson's equation and verification Potentiometric titration of acid and base. Cd in water-colourimetric method. Brass. 6. NO2. PVC. S2. Nylon. Anodizing of Aluminium--Characteristics of the coating. 9. Estimation of purity of Copper (Iodometric method) Estimation of purity of Alumiraum (EDTA method) Crystal growth (melt growth. Estimation of fluoride (Alizarind method) NItrate in water-colourimetric method 15. Cu. 12. 14.plots of E/V.5% salt solution (Steel) 18-8). 5. Bronze. Estimation of Pb. Corrosion potential measurement of certain metals and alloys in 3. Phenol formuldehyde-preparation and study of properties Urea formaldehyde-preparation and study of properties. A2E/AV2plots. 3.15 EN04-104A(P): CHEMISTRY LAB(A) (Common for AI. BM. Calculation of Junction potential) . 11.). Internal work assessment Lab practicals and record = 10 + 5 ( Lab performance to be evaluated by the thoroughness of the procedure and practices. etc. 10. 2. AFVAV. Estimation of SO2. Penguin Books Ltd. 14. Writing comprehensionSkills to express ideas in sentences.note taking and note making .Gandhian conceptsrecent advances in Indian science. 6. 7. Cambridge University Press. Intermediate English Grammar – Supplementary Exercise with answer” Cambridge University Press. Schrodinger. Encyclopedia Britannica. Anna University. Module IV (10 hours) Humanities in a technological age Importance of humanities to technology. Cambridge University Press. suffixes.punctuation . Bossel.giving instructions in an industrial situation . National Academy or Science. Bemal J..C. society and culture. Dampier W. Cambndge University Press. Engineering Ethics and the Environment. Tech. India. 15. journalistic articles. Vesilind. Thompson Press India Ltd. Larson E.D. Intermediate English Grammar. Science in History.. History of Science.. equipment and processes . Science and Human Values. education and society . . articles. 11. 2.idioms . 9. English Grammer . H. Harper and Row. Grammar Practice Activities. etc. programmes) 2 hours lecture per week Module I (10 hours) Introduction to English usage and grammarReview of grammar affixes.correspondence on technical topics -different types of technical reports Module III (14 hours) History of science and technology Science and technology in the primitive society .correction of mistakes .. History of Science in India. Orient Longman. Subrayappa. Cambridge University Press. Earth at a Crossroads . History of Technology. 4.the rise and development of early Indian science . essays.Cultural and industrial revolutions . 12. 13.relevance of a scientific temper -science. English Vocabulary in Use.An outline. McCarthy. Cambridge University Press Pennyor.impact of sciences and technology on societies . Brownoski J. 8. importance and characteristics of technical communication -correspondence on technical matters-aspects of technical description of machinery. Cambridge University Press. Cambridge University Press Murphy. English for Engineers and "Technologists..commonly misspelt words . Module II (10 hours) Technical communication and report writing Need. prefixes. History of Inventions. paragraphs and essays. Nature and Greeks and Science and Humanism. Reference Books: 1. Cambridge University Press Hasgemi.relation of career interests of engineers to humanities . Huddleston R. 10.105: HUMANITIES (Common for all B..style vocabulary building. graphic representation. 3.the development of human civilization from primitive to modern society. participles and gerunds -transformation of sentences . History of Science". 5.16 EN04 .contribution of Indian scientist-JC Bose CV Raman Visweswaraya-Ramanujam and Bhabha.paths to a sustainable Future. Reading comprehension Exposure to a variety of reading materials. 2 questions A and B of l5 marks from module I with choice to answer any one QIII.2 questions A and B of 15 marks from module IV with choice to answer any one . Internal work assessment One essay on relevant topic One Technical Report 2 Tests Total marks 2x15 10 10 = 30 = 50.2 questions A and B of 15 marks from module III with choice to answer any one QV .2 questions A and B of l5 marks from module II with choice to answer any one QIV .8 short type questions of 5 marks. Technical Communication-Principles and practice. University examination pattern QI . Meenakshi Raman etal. Oxford University Press.17 16. 2 from each module QII . ) b) Development of surfaces of solids . not for University Examination).perspective views of prisms. Module-IV (12 Hours . and sphere). prisms.II (16 Hours . and sectioned solids.isometric views .3 drawing exercises) a) Sections of solids . PT. cabinet and general oblique projections of solids and simple objects.method of parallel line.sections by planes parallel to the horizontal or vertical planes and by planes inclined to the horizontal or vertical planes.6 drawing exercises) a) Introduction to multiview projection of objects .106A: ENGINEERING GRAPHICS(A) (Common for AI. pyramids. involute and helix.lettering and dimensioning familiarization with current Indian Standard Code of practice for general engineering drawing. Construction of ellipse. cone.vertical. and cylinder. Development of solids having hole or cut. and cylinder. Development of polyhedra. cone. spheres. Module-V (12 Hours . angular and oblique perspectives . Construction of cycloid. pyramids and circles. (Solids to be drawn : Prisms. cone. cylinder. Projections of points in different quadrants. cone.principles of first angle and third angle projections. pyramids. parabola and hyperbola. tetrahedron. Line inclined to the two reference planes but parallel to the profile plane.cavalier.projections of solids with axis parallel to one plane and inclined to the other plane. Module .Classification of perspective views . Projections of solids with the axis inclined to both the planes.isometric scale . ( Solids to be drawn : Cube. (For practice only. radial line. CS.(Solids to be drawn : Cube.PT) 1 hour lecture and 3 hours drawing Module-0 ( 8 Hours -1 Drawing exercise) Drawing instruments and their use .3 drawing exercises) a) Projections of plane laminae of geometrical shapes parallel to one plane and inclined to the other plane . pyramids. cylinder.3 drawing exercises) a) Introduction to orthographic projections .traces of lines. Introduction to Computer Aided Drafting.visual ray method and vanishing point method of drawing perspective projection. EE.parallel. horizontal and profile planes . cube. BM. Module-III (12 Hours .3 drawing exercises) a) Introduction to isometric projection . b) True length and inclination of a line with reference planes. tetrahedron.isometric projections of prisms. sectioned solids and combinations of them. Principle of oblique projection . IC. pyramids.) Projections of solids on auxiliary planes. Line occupied in more than one quadrant. Module . IT. EC. line dimensioned in surveyor's unit. cone. b) Projections of polyhedra and solids of revolution . b) Introduction to perspective projections . Auxiliary projections of plane laminae. I triangulation and approximate developments.different types of lines .1 (12 Hours . Projections of laminae inclined to the two reference planes but perpenticular to the profile plane.frustums . Projections of combinations of solids.plane laminae inclined to both the planes. prisms.18 EN04 . True shape of section by projecting on auxiliary plane.the principle of the six orthographic views - . Orthographic projections of straight lines parallel to one plane and inclined to the other plane straight lines inclined to both the planes and occupied in one quadrant. tetrahedron. VIP Publications' 3.. Geomatrical Drawing ..C. Jet Publications 2. Internal work assessment Drawing exercises (Best 10) 2 Tests Total marks 10x3 2x10 = 30 = 20 = 50 University examination pattern No questions from module 0 QI . Tata McGraw Hill.2 questions A and B of 20 marks from module II with choice to answer any one QIII. Drawing of nuts. Gill P. Foundation bolts of eye end type. I. John K. LuzadderW.. b) Conventional representation of threaded fasteners.2 questions A and B of 20 marks from module I with choice to answer any one .. Elementary Engineering Drawing. S. bolts. Fundamentals of Engineeiing Drawing. Varghese. Engineerng (Graphics. Additional exercises where ever necessary may be given as home assignments.19 convertion of pictorial views of simple engineering objects into orthographic views. NOTE: All drawing exercises mentioned above are for class work. Prentice Hall of lndia. Reference books 4. and Kannaiiah P. Locking arrangements of nuts. washers and screws.D.2 questions A and B of 20 marks from module III with choice to answer any one QIV. J. P. Engineering Graphis. 5. 6. Narayanana K. Kataria and sons. hook end type and split end type.I. Bharr N.2 questions A and B of 20 marks from module I with choice to answer any one QII. Engineering Graphics. Bolted and Screwed joints. Text books 1. Charotar Publishing House.2 questions A and B of 20 marks from module IV with choice to answer any one QV . Types of trusses (Perfect.Resultant . Text Books 1.20 EN04 .Different types of supports. Module III (17 hours) Introduction to structural mechanics .Motion of vehicles on circular path. Introduction to vector approach (Application to simple problems only) . Work.Work-energy equation . sphere). IC.Rigid body rotation about a fixed axis .Applications to problems.Solution of problems by scalar approach. loads and beams .Motion of connected bodies. parallel and general system of forces . To acquaint the student with general methods of analyzing engineering problems 2. IT.Screw jack and its efficiency.Tangential and normal acceleration . Deficient and Redundant trusses) -Analysis of trusses Method of joints .M.Centroid of composite plane figures . Curvilinear motion .Rotation under the action of constant moment.Newton's second law. McGraw Hill Publishers .Polar moment of area .Reactions at supports. Kinematics of rotation . Timoshenko and Young.Simple contact friction problems .Torsional vibration. Properties of surfaces .107A: ENGINEERING MECHANICS(A) (Common for AI.Coplanar forces and Force systems -Resultant and equilibrium conditions for concurrent.Analysis of lift motion .Free body diagrams . To illustrate the application of the methods to solve practical engineering problems Module I (17 hours) Principles of statics . Power and Energy . EC.Centripetal and centrifugal forces .I of a lamina . circular rod. Module II (17 hours) Friction .Method of sections.M. "Engineering Mechanics".Transformation and conservation of energy .Equation of motion . Shear force and Bending moment in beams -Shear force and bending moment diagrams for cantilever and simply supported beams (only for concentrated and uniformly distributed load cases). Introduction to mechanical vibrations .Second moments of plane figures and composite sections .Work done by a force .Work of the force of gravity and force of spring .Resultant of force systems.Transfer theorems .Oscillation of spring .Wedge . BT.D'Alembert's principle -Motion on horizontal and inclined surfaces . PT) 2 hours lecture and 1 hour tutorial per week Objectives 1.Simple harmonic motion.Equilibrium of a particle in space Non-concurrent forces in space . BM.Theorems of Pappus-guldinus. Moment of inertia of a rigid body . Module IV (15 hours) Kinetics of rectilinear motion .Laws of friction . CH.Product of area and Principal axes (conceptual level treatment only).Concurrent forces in space . EE. Plane trusses . CS.I of 3 dimensional bodies (cylinder.free vibration .First moment and centroid of curve and area . Statics and Dynamics". Internal work assessment 60%. 2.Test papers (minimum) 30%.R.1 statics. and Johnson. "Mechanics for Engineers.. Vikas Publishing House. Q V .assignment should be computer based using spread sheet or suitable tools) Total marks = 50 University examination pattern QI . Vol II Dynamics.H. Shames.. Hibbeler. I. Pearson 3.2 questions A and B of 15 marks from module IV with choice to answer any one (QII to V can have subdivisions and at least 80 % weightage for numerical problems) .Statics and Dynamics". Rajasekharan and Sankarasubramanian. Vol.P.21 2. Prentice Hall of India. McGraw Hill Publishers. Engineering Mechanics. 2 from each module (in which atleast 5 questions to be Numerical) QII .2 questions A and B of l5 marks from module III with choice to answer any one. Reference Books 1. E. "Engineering Mechanics.2 questions A and B of 15 marks from module! with choice to answer anyone QIII -2 questions A and B of 15 marks from module III with choice to answer any one QIV . Beer.8 short type questions of 5 marks. "Engineering Mechanics".F. working . Inductors.DC equivalent model and analysis.Bias stability. current and resistance.Test papers (minimum 2 ) 30% . Tata McGraw Hill. colour coding and tolerance. PHI.comparison and basic applications. Capacitors-fixed and variable.2 questions A and B of 15 marks from module I with choice to answer any one . Resistors-fixed and variable.clipping and clamping circuits Transistors. Internal work assessment 60% . BT. L Electronic Devices and Circuit Theory.graphical representation of transistor characteristics.Electron motion in perpendicular electric and magnetic field.definition of stability factors-calculation of stability factor for potential divider biasing circuit. C.different resistor biasing circuits-various biasing technique. ripple factor. Electrostatic and magnetic deflection sensitivities.structural features. characteristics. Q-point-effect of Q-point location on allowable signal swing. Boggart T. Add S.Electron motion in parallel electric and magnetic fields. Vacuum diode.Assignments / Term project/any other mode decided by the teacher. AI. Boylestad. Module 3 (Hours 10) Graphical analysis of BJT operations. Milman. applications of CRO. N.Principle.The three configuration. Sedra and Kenneth C Smith. operation and VI characteristics.analysis of diode circuits-DC model of the diode. Module 4 (Hours 12) Rectifiers and power supplies . The ideal diode. different types.Motion of electron in Electric field .Series voltage regulator .analysis and design .terminal characteristics of practical diodes.Other measures like Regularity and Participation' in Class Total marks = 50 University Examination Pattern QI . Electronic Devices and Circuits. 10% . block diagram of CRO. Magnetic focusing-electrostatic focusing. and Halloas. Text Books 1. 3.Two dimensional motion of electrons in uniform electric field. PHI/Pearson 2. M. IC) 2 hours lecture per week Module .Biasing. R and Nashelsky. Module 2 (Hours 12) Electronic components (Brief discussion only-construction aspects not required). different types.l (Hours 10) Electron ballistics .Physical structure and modes of operation. CRT. UBS.F. 2 from each module QII . efficiency.Half wave and full wave rectifiers.8 short questions of 5 marks. collector feed back biasing. Electronic Devices and Circuits. Multimeter-principle of measurement of voltage.load line.potential divider biasing. J.principles of operation only. CRO.22 BM04 -108 : BASIC ELECTRONICS (Common for EC.analysis and design. Simple Zener regulator .LC and pi filters. Horenstein. DC output voltage. characteristics.Zener diodes.Junction filed effect transistors. rectification factor.using two DC sources. Microelectronic Reference books 1.rectifiers with filter: Inductive filter-analysis capacity filter.motion of electron in transverse magnetic filed. Relays and trans formers-different types. BM. 2. Definition and derivation of rectifier specifications such as PIV. triode and pentode. Micro Electronics Circuits. BT.Phase difference .Solutions of resistive circuits with dependent sources -Mesh analysis and Nodal analysis .Balanced 3 phase AC source supplying balanced 3 phase star connected and delta connected loads . average value. Alternating quantities .Definitions and explanations of the terms: wave form.Lenz's law .2 questions A and B of 15 marks from module I with choice to answer any one. parallel and series-parallel circuits with DC excitation . C.MMF . phase difference.Linier differential equations for series RL and RC. BM04 -109 : BASIC ELECTRICAL ENGINEERING (Common for EE. parallel RL and RC. .Q-factor . Module II (12 hours) Magnetic circuits . voltage/current inputs .potential gradient Dielectric strength.Determination of initial conditions. frequency.Dot convention. phase.Norton's theorem .Inductances in series and parallel . apparent power.2 questions A and B of 15 marks from module I with choice to answer any one QV.3 wire and 4 wire systems -Neutral current . BM.Solutions of series.23 QIII.Phase sequence -Star-delta transformation .Dynamically and statically induced emfs . Time domain analysis of circuits . trapezoidal and sinusoidal waveforms. series RLC and parallel RLC circuits .Energy stored in electrostatic fields . IC. rms value.Active and reactive powers . RL.Frequency response curves . Electostatics . Phasor representation of sinusoidal qualities .Series and parallel resonances .Apparent power .Linearity . EC. AI.Magnitisation curves of ferromagnetic materials . voltage. Module 1(10 hours) Elementary concept and definitions of current.Self and mutual inductances .Capacitance. admittance.Three phase AC circuits -Generation of 3 phase AC voltages".Coefficient of coupling . Basic network theorems . parallel and series-parallel AC circuits.Cumulative and differential connection of coupled coils.Nodal conductance matrix and mesh resistance matrix.Power factor .Charging and discharging of capacitor . time period.2 phase circuits . Module IV (10 hours) Analysis of polyphase circuits . Faraday's laws of electromagnetic induction . triangle.Balanced system .Average power .Natural response .Addition and subtraction of sinusoids -Symbolic representation . power and energy -Introductory circuit analysis .Cartesian. Two terminal element relationships .Active power.Solution of magnetic circuits.Generation sinusoidal emf. form factor and peak factor Calculations for square.2 questions A and B of I5 marks from module I with choice to answer any one QIV.Complex power .Bilateral & unilateral elements -Thevenin's theorem .Independent voltage and current sources-Dependent voltage and current sources Source transformation – Ohm’s law-Kirchoff 's laws -Solutions of simple series. active elements .Maximum power transfer theorem. conductance and susceptance .Comparison of magnetic and electric circuits . and power .Magnetic flux . cycle.Substitution theorem. polar and exponential forms.Power in single phase circuits Instantaneous power . reactive power.-Mathematical equations .Capacitors in series and parallel . RC and RLC circuits using phasor concept -Concept of impedance.V-I relationship for inductance and capacitance.Transient response -Time constant . PT) 2 hours lecture per week.Mutual flux and leakage flux . L. Analysis of ac circuits: R. Module III (12 hours) Single phase AC circuits. amplitude.Complete solution for step/dc.Parallel plate capacitor .Superposition theorem .Reluctance .Half power frequencies Bandwidth -Application of Thevenin's and Norton's theorems for AC circuits.Concept of a linear element .Concept of a linear circuit Passive vs.Rise and fall times . Text Books 1. Hughes E. Van valkenberg. University examination pattern QI .24 factor .2 questions A and B of 15 marks from module I with choice to answer any one QIII. Pearson Education.Three wattmeter and Two wattmeter methods. QII.Power factor. 10 % .2 questions A and B of 15 marks from module IV with choice to answer any one . Electric circuits and network analysis.2 questions A and B of 15 marks from module II with choice to answer any one QIV. Prentice Hall (India) PVT LTPT 3.Neutral shift (explanation and concept only) . McGraw Hill.Fundamentals of Electrical and Electronics Engineering Prentice Hall (India) PVT LTD. Edminister J A. D. 2. Reference books 1. improvement-Unbalanced systems . Electric circuits. Electrical technology. Smarjith Ghosh .2 questions A and B of l5 marks from module III with choice to answer any one Q V .8 short type questions of 5 marks 2 from each module. Kothari & Nagarth .Theory and problems of Basic Electrical Engineering Prentice Hall (India) PVT LTD. Total marks = 50.Three phase power measurement .Assignments/Term project/any other mode decided by the teacher.Other measures like Regularity and Participation in Class. Schaum's series.P. Internal work assessment 60 % -Test papers ( minimum 2) 30 % . 2. Welding Practice • Study of welding equipment and tools-safety practices. boring. Machine Shop Practice • Study of different machine tools-lathe-shaper-milling machine. 2. shearing/cutting machine. filing. bending. BM.drilling machine-grinding machine • Exercises on lathe-models involving straight turning. • Demonstration of brazing.110(P) : MECHANICAL WORKSHOP (Common for EC. soldering. and drilling . Sheet metal work • Study of tools and equipment for sheet metal work. AI. rectangular duct.25 BM04 . IC.use of thread dies and taps. forming. and joining operations-development & fabrication of simple sheet metal components like tray. facing. 3. BT) 3 hours practical per week 1. gas welding and cutting • Exercises involving preparation of different types of welded jointslap and butt joints. and thread machining-thread standards and specifications. Fitting Practice • Study of hand tools and measuring tools used in fitting work • Fabrication exercises involving cutting. taper turning. • Demonstration of electric arc welding. • Demonstration of special welding processes-welding defects and weldment inspection 4. Internal work assessment Workshop practicals and recor 2 tests Total marks 2x10 =30 =20 =50 . etc. cylindrical dish. chiseling. knurling. • Types of joints in sheet metal work-cutting. funnel. 26 BM04 - 111(P): ELECTRICAL AND ELECTRONICS WORKSHOP (Common for EE,EC, AI, IC,BT, BM, CS, IT, PT) 2 hours practicals per week Part A: Electrical Workshop (2 hours per alternate weeks) 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Familiarisation of various types of Service mains - Wiring installations Accessories and house-hold electrical appliances Methods of earthing - Measurement of earth resistance - Testing of electrical installations - Precautions against and cure from electric shock Practice of making Britannia joints on copper / aluminium bare conductors. Practice of making Married joints on copper / aluminium conductors. Practice of making T joints on copper / aluminium conductors Wiring practice of a circuit to control 2 lamps by 2 SPST switches. Wiring practice of a circuit to control 1 lamp by 2 SPDT switches. Wiring practice of a circuit to control 1 fluorescent lamp and 1 three-pin plug socket. Wiring practice of a main switch board consisting of ICDP switch, DB, MCB's, and ELCB's. Familiarisation of various parts and assembling of electrical motors and Wiring practice of connecting a 3-phase / 1-phase motor with starter = = = 15 10 25 Internal work assessment Workshop practicals and record Test/s Total marks Part B - Electronics Workshop (2 hours per alternate weeks) 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Familiarisation of various electronics components such as resistors, AF&RF chokes, capacitors, transistors, diodes, IC's and transformers. Assembling and soldering practice of single phase full wave bridge rectifiers circuit with capacitor filter. Assembling and soldering practice of common emitter amplifier circuit. Assembling and soldering practice of common emitter amplifier circuit on PCB. Assembling and soldering practice of non inverter amplifier circuit using OPAMP on PCB. Assembling of a timer circuit IC555, phase shift oscillator circuit using OPAMP and JK flip-flop using NAND gates on a bread-board. Coil winding - Single layer and multi layer - Demonstration. Miniature transformer winding – Demonstration. PCB layout using software like ORCARD, CIRCUITMAKER, EDWIN. PCB fabrication – Demonstration. Internal work assessment Workshop practicals and record = 15 = Test/s 10 Total marks = 25 27 THIRD SEMESTER EN04 - 301A ENGINEERING MATHEMATICS (Common for all B. Tech. programme except CS and IT) 3 hours lecture and 1 hour tutorial per week Module I Linear Algebra: Vector spaces- linear dependence and impedance, and their computation- Bases and dimensionSubspaces- Inner product spaces- Gram-Schmidt orthogonalization process- Linear transformations- Elementary properties of linear trans formations- Matrix of a linear transformation. (Proofs of theorems omitted) Module II Fourier Transforms: Fourier integral theorem (proof not required)- Fourier sine and cosine integral representationsFourier transforms- Fourier sine and cosine transforms- Properties of Fourier transformsSingularity functions and their Fourier transforms. Module III Probability Distributions: Random variables- Mean and variance of probability distributions- Binominal and Poisson distributions- Poisson approximation to binominal distribution- Hypergeometric and geometric distributions- Probability densities- Normal, uniform and gamma distributions. Module IV Theory of lnference: Population and samples- Sampling distributions of mean and variance- Point and interval estimations- Confidence intervals for mean and variance- Tests of hypotheses- Hypotheses concerning one mean, two mean, one variance and two variances- Test of goodness of fit. Text Books For Module I K. B. Datta, Matrix and Linear Algebra for Engineers, Prentice-Hall of India, New Delhi, 2003 (Sections: 5.1, 5.2, 5.3, 5.4, 5.5, 5.8, 6.1, 6.2, 6.3) For Module II C R Wylie & L C Barrett, Advanced Engineering Mathematics (Sixth Edition), McGrawHill. (Sections: 9.1, 9.3, 9.5) For Module III Richard A Johnson, Miller & Freund's Probability and Statistics for Engineers, Pearson Education, 2000. (Sections: 4.1, 4.2, 4.3, 4.4, 4.6, 4.8, 5.1, 5.2, 5.5, 5.7) For Module IV Richard A Johnson, Miller & Freund's Probability and Statistics for Engineers, Pearson Education, 2000. (Sections: 6.1,6.2,6.3,7.1,7.2,7.4,7.5,7.8,8.1,8.2,8.3,9.5) Reference Book: 1. Bernard Kolman & David R Hill, Introductory Linear Algebra with Applications (Seventh Edition), Pearson Education, 2003. 2. Lipschutz S, Linear Algebra - Schaum's Outline Series, McGraw Hill 3. Erwin Kieyszig, Advanced Engineering Mathematics (Eighth Edition), John Wiley & Sons. 4. Larry C Andrews & Bhimsen K Shivamoggi, Integral Transforms for Engineers, PrenticeHall of India, 2003. 5. Ronald E Walpole, et al, Probability and Statistics for Engineers and Scientists (Seventh 28 Edition), Pearson Education, 2004. Robert V Hogg & Elliot A Tanis, Probability and Statistical Inference, Pearson Education, 2003. 7. Chatfield C, Statistics for Technology, Chapman & Hall. 6. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x15 = = = = 15 30 05 50 University examination pattern Q1 - 8 short type questions of 5 marks, 2 from each module. QII - 2 questions A and B of l5 marks from module I with choice to answer any one QIII- 2 questions A and B of l5 marks from module II with choice to answer any one QIV - 2 questions A and B of 15 marks from module III with choice to answer any one QV - 2 questions A and B of l5 marks from module IV with choice to answer any one compiling and executing a program.29 BT04 302 : COMPUTER PROGRAMMING IN C (Common for all B.While statement-do while statement. Text books V.Lexical elements. Programming in ANSI C.Logical expressions.R. Reference Books: 1.Structures in Arrays. 2.Type def .Numerical constantsVariables. Programming with C..if else statement-nested if statement-switch statement.for statement-continue statement.Arrays in structures. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks = = = = 15 30 05 50 2x15 University examination pattern QI .library functions. programmes except CS. & Ritchie.Structures .Flow charts.Writing.Relational operatorsRelational expressions. D. Prentice Hall of India.Assignment expressions-Multiple assignments.Enumerated data types.Increment and Decrement operators.M.String processing.break statement..R & Prasad S. Tata McGraw Hill. 3.Arrays in functions. Tech.sequential files.Input and output. Computer Programming in C.8 short type questions of 5 marks.Arithmetic conversion.Pointers-Pointers and Arrays. .Arithmetic operators.Basic computer organization.Compilers and interpreters.Overview of C.2 questions A and B of 15 marks from module III with choice to answer any one. Venugopal K. New Delhi.Files. Kernighan B.2 questions A and B of 15 marks from module IV with choice to answer any one.Unions. local and static variables. IT& PT) 2 hours lecture and 2 hours practical per week Module I (12 Hours) Programming and problem solving.if statement. Rajaraman.Program structure.Arithmetic Expressions.Developing algorithms.Pointers and functionsLinear linked lists and list operations. Balaguruswamy.Bit level operators and applications.Conditional operator. The C Programming Language.go to statement. Prentice Hall of India.Precedence and associativity of operators..multi dimensional.2 questions A and B of I5 marks from module l with choice to answer any one QIII.Bit-wise operators.user defined functions. Q V .Conditional statements.Fundamental data types. Module lV (20 Hours) Arrays.Steps involved in computer programming.2 questions A and B of 15 marks from modules II with choice to answer any one Q IV. Module III (16 Hours) Compound statements.text files.Debugging a programDescription of a programming language.Loop control statements.unformatted files.Format specifiers .Stacks-Strings.Global.Logical operators. from each module QII .High level and low level languages. Tata McGraw Hill. W.Recursion.single dimensional.Functions. Module II (18 Hours) Basics of C. structure.pigments .2 questions A and B of I5 marks from module l with choice to answer any one QIII.centrifugation elutriation. Text/Reference Books: 1.cell line .theories of carcinogenesis.fluidity in plasma membrane . Microbodies .ultrastructure .mechanism of photosystem.chemical composition .cellular aging .30 BT04 303 : CELL BIOLOGY 3 hours lecture and 1 hour tutorial per week Module I Introduction to cell theory . Module III Plastids .extra cellular structure . polymorphism.pores .interphase nucleus .tissue hornogenization . Darnell.microsomes .functions . ultrastructure and functions of endoplasmic reticulum .H. chemical composition and functions of golgi complex.characterization of cells . Chapman and Hall. from each module QII . Kimball T.2 questions A and B of 15 marks from modules II with choice to answer any one . stability.cell culture -cell fractionation .karyokinesis – cytokines is .morphology of eukaryotic chromosomes . Wesley Publishers Smith and Wood : Cell Biology. Lodish and Baltimore : Molecular Cell Biology.generation of cell lines maintenance of stock-cells .molecular organization of chromosomes Module IV Cell division . Ribosomes .chemical composition biogenesis .functions.permeability and transport .8 short type questions of 5 marks.W : Cell Biology.plant and animal cells .cell as a polyphasic colloidal system .biogenesis – functions. Module II Cytoplasmic vacuolar system .respiratory chain .shape and size -ultrastructure .redox potential .process and significance of meiosis .regulation of cell size .structure of plant cell wall and bacterial cell wall.chloroplasts .cytoplasmic events .glycocalyx functions of plasma membrane .morphological analysis techniques . 3.spermatogenesis and cogenesis Cell growth .ultrastructure and chemical composition of plasma membrane -membrane asymmetry . Mitochondria . Structure and functions of centriole .morphology.mitosis .immuno cytochemistry . 2.phycobilins – photochemical reaction systems . Techniques for the propagation of prokaryotic and eukaryotic cells .mitochondrial and chloroplast ribosomes – chemical composition . enzymes. Freeman = = = = 15 30 05 50 Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x15 University examination pattern QI . W.cell number .prokaryotic cells .eukaryotic cells . biogenesis and functions of lysosomes.structure. flow past immersed bodies and motion of particles through fluids.unit operations and unit processes . 3. Reference 1.work done . blowers and compressors and detailed study of Centrifugal pumps .31 Q IV.excess reactants .pump characteristics.Bernoulli equation. from each module QII .various types of centrifugal pumps. Overall and component material balances . Q V . Energy balance for systems with and without chemical reaction.pitot tube .Hagen Poiseuille equation . Heat and Mass Transfer.2 questions A and B of 15 marks from module IV with choice to answer any one . Q V . Friction losses in a pipeline and losses in various fittings .Laminar and turbulent flow through pipes . Module IV Fluid moving machineries . Module II Concepts and calculation involving energy . BT04 304 : CHEMICAL ENGINEERING I 3 hours lecture and 1 hour tutorial per week Module I Overview of process industry . 2.2 questions A and B of 15 marks from module IV with choice to answer any one.Reynold's number .equivalent length .2 questions A and B of 15 marks from module III with choice to answer any one. Ch. W. Stoichiometric and composition relations .McCabe & J.cavitation .2 questions A and B of I5 marks from module l with choice to answer any one QIII. Unit Operations in Chemical Engineering.specific speed .Smith . Mechanism of non-compressible fluid flow .conservation of mass and energy – SI units and conversion factors . Momentum.2 questions A and B of 15 marks from modules II with choice to answer any one Q IV.degree of completion of reaction. McGraw Hill. Process Calculation for Chemical Engineers.Durgaprasad & DVS Murthy.power consumption and efficiency.general study of various pumps.priming .rotarneter notches and weirs .8 short type questions of 5 marks.minimum starting speed .theological classification. Heats of formation.friction factor. solution and dilution and the effect of pressure and temperature on them. combustion.L. Measurement of fluid flow -orifice and venturimeter .distribution of velocities .2 questions A and B of 15 marks from module III with choice to answer any one. Reynolds and Cotburn. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x15 = = = = 15 30 05 50 University examination pattern QI . Fundamentals of mixing and characteristics of mixing equipments .the concept of NPSH .gram atom and gram mol concepts .material balance involving chemical reaction and not involving chemical reaction. . Principles of particulate and aggregative fluidization.C. Module III Properties of fluids and units . heat and work and enthalpy of reversible and irreversible processes. induction of growth .interactions among soil microorganisms..continuous culture .phase contrast microscopy . Reproduction in bacteria .32 BT04 305 : MICROBIOLOGY 3 hours lecture and 1 hour tutorial per week Module I History and development of microbiology . yeasts.the coliform groupbacteriological methods of examining water. actinomycetes. Microbiology of water . Kapoor and Yadav : An Introduction to Microbiology.types of sterilization .of microscopy . 2 from each module. Wiley Eastern Ltd. preservation and maintenance of cultures.microbial diversity . .control of microorganisms by physical and chemical agents.growth of bacteriophage-macromolecular synthesis and growth.measurement of cell growth .preservation of foods.8 short type questions of 5 marks.kinetics of growth . Microbial flora of soil . Tata McGraw Hill. Pelczar et al: Microbiology.fluorescence microscopy . luegreen algae.generation time .2 questions A and B of l5 marks from module I with choice to answer any one QIII.genetic methods in taxonomy . New Delhi 2. Text/Reference Books: 1. actinomycete.isolation. Effect of environmental factors on growth. fungi. 1986 3.nutritional groupings of microorganisms . Principle.2 questions A and B of 15 marks from module II with choice to answer any one QIV.electron microscopy.brief outline on the taxonomy. Module IV.enumeration of microorganisms . QII .microbial spoilage of foods . fungi and virus .2 questions A and B of 15 marks from module III with choice to answer any one QV . Prescott et al : Microbiology. Microbial flora of fresh foods . Tauro. Principles of sterilization .growth medium and different types of media .bright field microscopy .microbiological characteristics of waste water. microbial phylogeny and current classification of bacteria. Principles of microbial taxonomy .growth factors .gram staining .restriction of growth and synchronous culture . Theory of staining microorganisms . McGraw Hill. Module III Growth . USA Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x15 = = = = 15 30 05 50 University Examination Pattern QI .growth curve .2 questions A and B of l5 marks from module IV with choice to answer any one. reproduction and survival of microorganisms.physiology of reproduction and sporulation.international rule for nomenclature. algae and virus. Module II Nutritional requirements of microorganisms . yeast.mass culture .flagella staining. morphology and ultrastructure of bacteria.Bacteriological evidence of pollution . 2 from each module.2 questions A and B of 15 marks from module III with choice to answer any one QV .L. QII . Hill et al : Principles of Biochemistry. Module III Lipids .structure and functions of DNA and RNA .classification of proteins .glycoproteins .activation energy and transition state enzyme activity -active sites . biochemistry : a historical perspective. Smith.A. Vitamins .nucleosides and nucleotides -structure of nucleic acids .biological function of B complex Vitamins and Vitamin C Text / Reference Books: 1.2 questions A and B of 15 marks from module II with choice to answer any one QIV.double helical model of DNA structure .essential fatty acids . E. W.H. Vitamin D.peptide bond .8 short type questions of 5 marks. Leninger: Principals of Biochemistry. Carbohydrates — structure and properties of monosaccharides. 2. Vitamin K and Vitamin E .sialic acids -bacterial cell Wall polysaccharides . Vol.glycerides .L.base pairing rule . CBS Publications. tertiary and quarternary structure of proteins -purification of proteins .theories of enzyme specificity .primary.muco poiysaccharides .general reactions of amino acids . .membrane glycoproteins and their biological functions .classification and structure . Freeman & Co. Module IV Enzymes .structure and properties of amino acids .fibrous and globular proteins. oligo saccharides and polysaccharides . B and Z DNA. Module II Amino acids and Proteins .hydrolysis of fats structure and properties of phospho lipids and glycolipids .1 and II.chemistry and biological functions of fat soluble Vitamin A. A. McGraw Hill Book Company. biological properties and uses of cholesterol. R.ring structure and muta rotation — homo and hetero polysaccharides .denaturation and renaturation .Nomenclature and classification of enzymes .2 questions A and B of l5 marks from module I with choice to answer any one QIII.2 questions A and B of l5 marks from module IV with choice to answer any one.water soluble vitamin B complex . Lubert Stryer : Biochemistry. secondary. Nucleic acids . Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks = = = = 15 30 05 50 2x15 University Examination Pattern QI .blood group substances.33 BM04 306 : BIOCHEMISTRY I 3 hours lecture and 1 hour tutorial per week Module I Introduction to.L.role of cofactors in enzyme catalysis.structure and properties of purine and pyramidine bases . 3.prostaglandines.structure. 5. filtration. Environmental sample analysis. disinfection. spore. 10. pour plate. 7. agar.total N 6. nephalometry/ turbidometry or dry weight. Growth curve of bacteria. pure culture technique. Quantification of microorganisms: counting microscopy. IMVic test. Isolation and preservation of bacterial culture Identification of microorganisms: staining techniques. 2. 8. confirmed test. 4. fungal staining.cotton plugging and sterilization. SPC. . Clinical Microbiology Internal work assessment Regular work and record Tests Regularity Total marks = = = = 25 20 5 50 . streak plate. Culturing of microorganisms: broth. bacteriological analysis of water. 9. Cultivation of moulds and yeast. Food microbiology: milk. dry heat. Preparation of culture media . Sterilization techniques (lecture & demonstration)) wet heat. 3. biochemical tests.34 BT04 307(P) : MICROBIOLOGY LAB 3 hours practical per week 1. presumptive test. capsule. fermented food. 2. 3. Precipitation by sodium sulphate. Extraction of lipids. 5. 11. Qualitative tests for Amino Acids.35 BT04 308(P): BIOCHEMISTERY LAB 3 hours practical per week 1. Estimation of Nucleic Acids. Estimation of cholesterol. Quantitative method for Amino Acids. precision and Accuracy. Protein estimation Biuret. Test for ribose and deoxyribose Enzyme assays: Phosphatase from potato. Units. Ninhydrin method . 6. 9. 10. 8. Internal work assessment Regular work and record = 25 Tests = 20 Regularity = 5 Total marks = 50 . Phospholipids: Ashing and estimation of phosphate. 4. PTH. measurements. Sensitivity. pH. concentrations units. Preparation of buffers. Spectrophotometry and Bradford Assay. Acid hydrolysis of Proteins and Estimation of Amino acids by Ninhydrin. Trypsin digestion of proteins. Folin's. Qualitative tests for Carbohydrates. 7. Saponification of Fats. oPA. Specificity. Amylase from sweet potato. Volume/Weight measurements. Estimation of Reducing sugars by the Benedict's method. 12. IV (Common for all B. 12.4. Advanced Engineering mathematics (8th Edition) John Wiley & Sons Module I Sections: 12.Conformal mapping.Generating functions-Relations between Legendre polynomials.8. C R Wylie & L C Barrett. 12.6.2.Trigonometric functions.15.Derivatives and analytic functions.D'Alembert's solution of the one dimensional wave equation. 11.Exponential functions. Module II (13 hours) Functions of a Complex Variable II: Line integral in the complex plane. 11. 12. Module III (13 hours) Series Solutions of Differential Equations: Power series method for solving ordinary differential equations. 13.3.4.Taylor series.36 FOURTH SEMESTER EN04 401A : ENGINEERING MATHEMATICS .Relations between Bessel functions.evaluation of real integrals.Laurent series-Singularities and zeros.4.Residues and residue theorem.7.1.Logarithm.Rodrigue's formula. Frobenius method for solving ordinary differential equations.2.5. 11.Legendre's equation and Legendre polynomials. 4.15. 12.3.1.1. Advanced Engineering Mathematics (Sixth Edition).3.14.Bessel functions-Generating functions. programmes except CS and IT) 3 hours lecture and 1 hour tutorial per/week Module I (13 hours) Functions of a Complex Variable I: Functions of a complex variable.Classification of linear PDE's-Derivation of the one dimensional wave equation and the one dimensional heat equation.15.15.Solutions of these equations by the method of separation of vari-ables.Linear functional transformations.5 Module IV Sections: 11. 12. 11.Solutions satisfying initial and boundary conditions. 13.Hyperbolic functions.Steady state two dimensional heat flow.2.Orthogonality property of Legendre polynomials( proof omitted).Cauchy's integral theorem (Proof of existence of indefinite integral to be omitted). 4. .Cauchy-Reimann equations.9 Module II Sections: 13. Tech.1.Orthogonality properties of Bessel functions (proof omitted).3. 4.Derivatives of analytical functions ( proof to be omitted).4 Module III Sections: 4.4.Cauchy's integral formula.Laplace equation.3. 12. Module IV (13 hours) Partial Differential Equations: Basic concepts. Text Book: Ervin Kreyszig.5 References 1.Bessel's equation. QII . Brown J W & Verhey R F. Engineering Mathematics . Prentice Hall of India. Churchill R V. Sastry S S. Complex Variables and Applications.37 2.2 questions A and B of l5 marks from module I with choice to answer any one QIII. McGraw Hill.2 questions A and B of 15 marks from module II with choice to answer any one QIV. .2 questions A and B of 15 marks from module III with choice to answer any one QV . Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x15 = = = = 15 30 05 50 University Examination Pattern QI . McGraw Hill Michael D Greenberg. Advanced Engineering Mathematics (Second Edition) Pearson education Asia. McGraw Hill.8 short type questions of 5 marks. Applied Mathematics for Engineers & Physicists. 2 from each module.Volumes 1 & 2. Pipes LA & Harvill L R. 4.2 questions A and B of l5 marks from module IV with choice to answer any one. 5. 3. Mineral resources: Use and exploitation.water pollution. poaching of wild life man. estuaries).ecological succession. food webs and ecological pyramids .water resources: Use and over utilization of ground and surface water. productive use.Structure and function of an ecosystem-producers.Land resources: Land as a resource. structure and function of the following ecosystems: Forest ecosystem.conservation of bio diversity : in-situ and ex-situ conservation of bio diversity Module III (11 Hours) Environmental pollution Definition-causes. effects and control measures of :-air pollution. Module II (12 Hours) Ecosystem: Concept of an ecosystem.38 EN04 402 : ENVIRONMENTAL STUDIES (Common for all branches) 3 hours lecture and 1 hour tutorial per week Objective: The importance of environmental science and environmental studies cannot be disputed. man induced land slides. deforestation. characteristic features. case studies .noise pollution-thermal pollution.Energy resources: Growing energy needs. mining.wildlife conflicts.soil pollutionmarine pollution. water logging.nuclear hazards.threads to bio diversity: habitat loss. types. loss of bio diversity etc.bio geographical classification of India. loss of forest. case studies . oceans.India as a mega diversity nation . use of alternate energy sources.Bio diversity at global. aesthetic. case studies. ethical. renewable and non renew-able energy sources. soil erosion and desertification.solid waste management: .Food Chains. solid waste disposal. floods.hot spots of Bio diversity. Timber extraction. streams. Continuing problems of pollution.value of bio diver-sity: consumptive use. national. dam benefits and problems. Land degradation. social.Scope and importance. changes caused by agriculture overgrazing. dams and their defects on forests and tribal people. salinity. consumers and decomposers.forest resources: use and over exploitation. conflicts over water. effects of modem agriculture.role of an individual in conservation of natural resources. species and ecosystem diversity. have made everyone aware of environmental issues. fertilizer-pesticide problems. and local levels . The objective of this course is to create general awareness among the students regarding these environmental issues Module 1 (12 Hours) The multidisciplinary nature of environmental studies Definition. Bio diversity and its conservation Introduction-definition: genetic.Introduction.endangered and endemic species of India . case studies Food resources: world food problems.Equitable use of resources for sustainable life style. lakes. drought. and option values .Energy flow in the ecosystem. Natural Resources Renewable and non renewable resources: Natural resources and associated problems.need for public awareness. rivers. degradation of environment.grassland ecosystem desert ecosystem -aquatic ecosystem (ponds. environmental effects of extracting and using mineral resources. 639p. Heywood.Environmental ethics: Issues and possible solutions.net 3.P. & Datta. Mckinney. A.P.. 9. Co. 1995.T. Environmental Protection and Laws. Townsend.B..C.39 causes.consumerism and waste products. 5. 574p. Techno-science Publications 3. Press. Encyclopedia of Indian Natural History. R. India. Nidi Publ. Stockholm Env. M. 5.forest conservation act -issues involved in enforcement of environmental legislation. V. Jadhav. Himalaya Pub.HIV/AIDS-social concern. acid rain. Web enhanced edition. H. global warming. Bikaner. Water in crisis. Gleick.Disaster management: Floods.Human rights for clean environment.Role of information technology in environment and human health. & Bhosale.Value education.population explosion. rain water harvesting. Clark.K. Mapin Publishing Pvt. P. 12. Visit to local polluted site.G Jr. E & Hepworth. E. Oxford & IBH Publ. Mhaskar A. McGraw Hill Inc. Brunner. Delhi. water shed management.river/forest/ grassland/hill/mountain. Matter Hazardous.pollution hazards. Module IV (10 Hours) Social Issues and the environment From unsustainable to sustainable development. Centre for Science and Environment. Environmental Science system & Solutions.M.water conservation. Introduction to air pollution.pollution case studies .H. Waste Water treatment. Pvt. case studies. sanitation and health. Pacific Institute for Studies in Dev. Cooper. Cyclone and Land slides. & Watson. 6.case studies. 1993. 4. T. Biodiversity of India. C. effects and control measures of urban and industrial wastes-role of an individual in prevention of pollution. river. H. R. W. Ltd. R. Marine Pollution. Down to Earth. Text books 1..Science Publications. V. R. Oxford Univ..urban/rural/industrial/agriculture Study of common plants/insects/birds Study of simple eco systems.pond. Hawkins. Clanderson Press Oxford 2. Blackwell Science. Ltd. . Rao.K. M. M. 2001 Environmental encyclopedia Jaico publ. A. and Goel. 1989. 7..E. K. & School. Miller. ozone layer depletion.resettlement and rehabilitation of people. Harper.Women and child welfare. House. Bombay. Bharucha Erach. R.environmental protection act. Institute.public awareness. Bombay Natural History Society. 4. USA. 1971. Environmental Chemistry.N. Ltd. Global Biodiversity Assessment Cambridge Univ.M.2001 Environmental biology. Trivedi.S.H. 480p. variation among nations.K.Saunders Co.. 11. W. Field work (5 Hours) Visit to a local area to document environmental assets. Wiley Eastern Ltd. Reference Books 1. Human population and the environment Population growth. Press 1140p. earth quake.water (prevention and control of pollution) act . 473p. T. 1995..urban problems related to energy. J. 13. Gorhani. and Michael Begon. R. Email:
[email protected]. Agarval. House Mumbai 1196p. case studies.air (prevention and control of pollution) act .K 1987.T. 1996. Hazardous Waste Incineration. Ahmedabad-380 013. 8. Techno . Essential of Ecology. its problems and concerns. 2. 10.waste land reclamation. Odum.wild life protection act. Cunningham.P. Wadsworth Publishing Co.climate change.Family welfare programmeEnvironment and human health. Environment and security. nuclear accidents and holocaust. hill slopes etc. Environmental Science.L. Fundamentals of Ecology.K. De. 16. Rules. 15. Meerut. USA 499p Magazine. . B. K. Wagner. Enviro Media. Survey of the Environment.2 questions A and B of 10 marks from module l with choice to answer anyone QIII. 17. R. Saunder Co. 2001. 14. D.2 questions A and B of 15 marks from module II with choice to answer any one QIV. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x15 = = = = 15 30 05 50 University Examination Pattern: QI . The Hindu (M). Trivedi.40 345p.2 questions A and B of l5 marks from module IV with choice to answer any one. Guidelines. Vol. 1998. Environmental Chemistry. Goel Publ. I and II.2 questions A and B of 15 marks from module III with choice to answer any one QV . Sharma.K. W. House.K.. Philadelphia.16 short answer questions(4 from each module) of 5 marks each with choice to answer any 12(12x5) QII .B. Compliances and Standards. Environmental Management. Handbook of Environmental Laws. H.41 BT04 403 : BIOCHEMISTRY II (Common with AI 04 403) 3 hours lecture and 1 hour tutorial per week Module I Metabolism of carbohydrates .2 questions A and B of 15 marks from module III with choice to answer anyone QV .essential and non-essential amino acids . Leninger: Principles of Biochemistry. CBS Publications. R. I and II.salvage pathways of purines and pyrimidines . regulation and its linkage with the citric acid cycle metabolism of aromatic amino acids.8 short type questions of 5 marks.2 questions A and B of 15 marks from module IV with choice to answer any one . 3.L. sucrose and starch .reactions. Module III Metabolism of nucleic acids . Module IV Bioenergetics . Metabolism of proteins .glycogenolysis and glycogenesis . histidine and serine.pentose phosphate pathway and its significance .Denovo biosynthesis of purine and pyrimidine nucleotides regulation of purine and pyramidine nucleotide biosynthesis . McGraw Hill Book Company.2 questions A and B of 15 marks from module II with choice to answer any one QIV .degradation and biosynthesis of amino acids . Vol. A.cholesterol metabolism. 2 from each module QII -2 questions A and B of 15 marks from module I with choice to answer any one QIII.. Lubert Stryer : Biochemistry. 2.photosynthesis.redox potential . energetics and regulation of glycolysis .formation of deoxyribonucleotides . Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks = = = = 15 30 05 50 2x15 University Examination Pattern QI . Text / Reference Books: 1.maintenance of blood glucose levels . W.gluconebgenesis pathway and its regulation biosynthesis of lactose.ATP production chemiosmotic theory .control of glycogen metabolism .ketosis .biological oxidation . cystein.fatty acid oxidation .uncouplers and inhibition of oxidative phosphorylation. Freeman & Co.respiratory control -oxidative phosphorylation . Hill et al: Principles of Biochemistry.metabolism of phospholipids .mitochondria and components of electron transport system .TCA cycle . E. Module II Metabolism of lipids .urea cycle : reactions.ketone bodies .catabolism of purines and pyrimidines. Smith.biosynthesis of fatty acids and triglycerides .L.L. design principles of heat exchangers .concept of two dimensional conduction .properties of solids .factors affecting evaporation . 3.conduction through series resistances convection -extended surfaces -the. Module IV Individual and overall heat.C and Van Ness: Introduction to Chemical Engineering Thermodynamics.heat conduction .closed and open circuit grinding Screening . Centrifugal separation -Principles of conveying of solids Module III Mechanism of heat transfer . Module II Mechanical operations . Theories -of filtration and washing . .natural convection . temperature relations of fluids .efficiency of screens.types of equipments for size reduction -laws of crushing-power requirement .thickening.calculations for single effect and multiple effect evaporation.boiling and condensation heat transfer to Non Newtonian fluids .types of heat exchangers .shape factors forced convection in pipe and other geometries .42 BT04 404 : CHEMICAL ENGINEERING II 3 hours lecture and 1 hour tutorial per week Module I Chemical Engineering Thermodynamics .optimum cycle.transfer coefficients .concepts of chemical potential and fugacity-thermodynamics of fluid flow compression and expansion of fluids . Smith H.general equations of equilibrium .pressure. Mc Cabe and Smith: Unit Operations in Chemical Engineering.equilibrium criteria for homogeneous chemical reactions evaluation of equilibrium constant.free and hindered settling .constant pressure and constant rate filtration .quantitative development of the fundamental laws -thermodynamic functions . 2 from each module.basic laws of radiation. Brown: Unit Operation.8 short type questions of 5 marks. Text/Reference Books: 1 2. Badger and Banchero: Introduction to Chemical Engineering Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x15 = = = = 15 30 05 50 University Examination Pattern QI . 4. Sedimentation . volume. design and usage of various commercial media for industrial fermentations. Bioprocess Engineering. examples of simple and complex media.2 questions A and B of l5 marks from module III with choice to answer any one QV . solid-substrate fermentation and its applications. sterilization of liquid media. filter sterilization of liquid media. Bailey and Ollis. elemental balances. minerals. Design of sterilization equipment.2 questions A and B of 15 marks from module II with choice to answer any one QIV . An overview of aerobic and anaerobic fermentation processes and their application in the biotechnology industry. Module III Metabolic stoichiometry and energetics: Stoichiometry of Cell growth and product formation. Air. thermodynamic efficiency of growth. Module II Fermentation processes: General requirements of fermentation processes. thermal death kinetics of micro organisms. Main parameters to be monitored and controlled in fermentation processes. References 1. outline of an integrated bioprocess and the various (upstream and downstream) unit operations involved in bioprocesses. Techniques of enzyme immobilization. Enzymatic bioconversion processes: Kinetics and thermodynamics of enzyme-catalyzed reactions.43 QII . carbon. BT04 405 : BIO PROCESS PRINCIPLES 3 hours lecture and 1 hour tutorial per week Module I Introduction to bioprocesses: Historical development of bioprocess technology. McGraw Hill 2. basic design and configuration of immobilized enzyme reactors. available. Prentice Hall Internal work assessment Assignments (minimum 2) 2 tests = 15 = 30 2x15 . oxygen consumption and heat evolution in aerobic cultures.2 questions A and B of l5 marks from module IV with choice to answer any one. applications of immobilized enzyme technology. role of bioprocess engineer in the biotechnology industry. yield coefficients of biomass and product formation. vitamins and other complex nutrients.2 questions A and B of 15 marks from module I with choice answer any one QIII. nitrogen. Biochemical Engineering Fundamentals.batch and continuous heat. generalized process flow sheets. Module IV Media design and sterilisation for fermentation processes: Medium requirements* for fermentation processes. degrees of reduction of substrate and biomass. maintenance coefficient Energetic analysis of microbial growth and product formation. an overview of traditional and modern applications of biotechnological processes. Basic design and construction of fermentor and ancillaries. medium formulation for optimal growth and product formation. oxygen requirements. electron balances. Shule and Kargi. types.liquid scintillation counters .development of Rf value.44 Regularity Total marks = 05 = 50 University Examination Pattern QI .thin layer chromatography. Module II Chromatography : Partition chromatography .Geiger counters— strip counters .mobile and stationary phases paper chromatography -solvent systems .G.2 questions A and B of 15 marks from module V with choice to answer any one. Dialysis .. UV visible. Module IV Radio isotope techniques . atomic absorption.gas chromatography and high performance liquid chromatograph (HPLC).preparation and activation of ion exchange materials .application of filtration techniques. IR. disintegration of cells .separation of macromolecules . photoelectric colorimeters. Column chromatography .immuno electrophoresis . BT04 406 : ANALYTICAL TECHNIQUES BIOTECHNOLOGY (Common with A104 406) 3 hours lecture and 1 hour tutorial per week Module I Photometry and spectrophotometry : The Beer-Lambert Law. Willard Merrit and Deana Settle : Instrumental Methods of Analysis.gradient elution .ultrafiltration. NMR and mass spectrophoto meters. density gradient centrifugation. CBS Publishers & Distributors. spectrophotometers .labeling of biological material with radioactive isotope -scintillation counting . 3.separating membranes .two dimensional chromatography .analysis of fraction and elution profiles .enzyme linked immuno absorbant assay(ELISA) .2 questions A and B of l5 marks from module I with choice to answer any one QIII . Module III Electrophoresis . Peck : Analytical Biochemistry. Text / Reference Books 1.isoelectric focusing . D.2 questions A and B of 15 marks from module IV with choice to answer any one QV. .ascending and descending techniques .8 short type questions of 5 marks. 2 from module QII . analytical ultracentrifuge .ion exchange chromatography ..radioactive disintegration . percentage transmittance and absorbance .radioactive isotopes used in biology detection of radioactivity .2 questions A and B of 15 marks from module III with choice to answer any one QIV . Longman..preparation of cellular organelle and other materials . Cooper : Tools of Biochemistry. Wiley Interscience 2. Differential centrifugation . T. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x15 = = = = 15 30 05 50 .determination of molecular weight.paper and gel electrophoresis .factors affecting dialysis gelfiltration . Holme and H.preparation of columns .autoradiography.affinity chromatography .two dimensional electrophoresis – capillary electrophoresis. 45 University Examination Pattern QI - 8 short type questions of 5 marks, 2 from module QII - 2 questions A and B of l5 marks from module I with choice to answer any one QIII - 2 questions A and B of 15 marks from module III with choice to answer any one QIV - 2 questions A and B of 15 marks from module IV with choice to answer any one QV- 2 questions A and B of 15 marks from module V with choice to answer any one. BT04 407(P) : CHEMICAL ENGINEERING LAB I 3 hours practical per week 1. 2. 3. 4. Drag coefficient of a falling sphere in a fluid. Pressure drop of liquid passing through a packed bed. Characteristic curves of a centrifugal pump and determination of maximum efficiency. Determination of the coefficient of discharge of orifice meter and venturi meter. Pressure drop characteristics in a fluidized bed. Verification of the laws of crushing using a ball mill Sieve analysis Effectiveness of a screen batch leaf filter. 5. 6. 7. 8. 9. Determination of the mean specific cake resistance and the compressibility factor using a 10. Batch sedimentation of a slurry. Internal work assessment Regular work and record Tests Regularity Total marks = = = = 25 20 05 50 46 BT04 408(P) : BIO-ANALYTICAL TECHNIQUES LAB 3 hours practical per week 1. 2. 3. 4. Verification of Beer - Lambert law using calorimeter Estimation of inorganic phosphate. Absorption spectra of nucleotides and bases Separation of aminoacids by paper chromatography - determination of Rf value. Extraction of lipids from tissues and their separation using TLC. Column chromatography of proteins Determination of molecular weight of an enzyme by gel filtration. Separation of proteins by SDS-PAGE. Isotope techniques - labeling of cellular constituents of E. coli. 5. 6. 7. 8. 9. Internal work assessment Regular work and record Tests Regularity Total marks = = = = 25 20 5 50 47 FIFTH SEMESTER BT04 501: INDUSTRIAL BIOTECHNOLOGY 3 hours lecture and 1 hour tutorial per week Module I Market Economics relating to modem Industrial Biotechnology in India. Various thrust areas and a study of some major biotech companies in India. Government initiatives. Outlook for the future. Isolation, Preservation, and Improvement of industrial microorganisms for overproduction of primary and secondary metaboloites - Regulation of enzyme activity and synthesis, Catabolite and phosphate regulation, Use of mutants in overproduction. Production of commercially important enzymes: Proteases, Amylases, Lipases, Celluloses, Pectinases, Isomerases ( Glucose Isomerase) and their uses. High-Fructose Corn Syrup Production. Module II Production of primary Metabolites: A brief outline of processes and conditions for the production of some commercially important metabolites, - Organic acids - Citric acid (surface and submerged processes), Acetic acid (Frings Trickling Generator, Submerged production), Lactic acid (batch production), Gluconic acid. - Amino acids - Glutamic acid (biotin and cell permeability effect on production), Lysine (production regulation using mutants), Aspartic acid. - Alcohols - Ethanol (Raw material selection/batch, Melle Boinot and Biostil processes, various recovery methods, by product recovery, biodiesel) Module III Production of secondary metabolites: Study of industrial production processes for various classes of low molecular weight secondary metabolites - Antibiotics - beta-lactams (Penicillins, Cephalcsporins etc.), Production of synthetic and semi synthetic penicillin - difference between natural and synthetic penicillins amino glycosides (streptomycin, ,kanamycin), Macrolides (erythromycin), Aromatic antibiotics (chlorcphenicol, griseofulvin), - Vitamins (B12, Riboflavin) and bioconversion of steroids. . . Module IV Production of Health care Products Proteins having therapeutic and diagnostic applications ( insulin, interferon, human growth hormone)- production of bacterial vaccines, Ergot alkaloids. Specialty bioproducts Bioproducts for agricultural food and -pharmacestical industries - Biopesticides, Biofertilizers Natural bio -preservatives (Nisin), Biopolymers (Xanthan gum and PHB) - Single cell proteins from various substrates (pruteer--, Symba, Bell process). 2.Comprehensive Biotechnology. Industrial Microbiology. Pergamon Press. . E. Wulf Crueger and Anneliese Crueger. QII .2 questions A and B of 15 marks from module IV with choice to answer anyone.5 2x15 = = = = 15 30 05 50 University examination Pattern QI .2 questions A and B of l5 marks from module I with choice to answer any one. L.8 short type questions of 5 marks.Publishers & Distributors.. 5. Microbiology.48 References 1. Michael Waites. Panima Publishing. 4.2 questions A and B of 15 marks from module III with choice to answer any one. QIII. Cascida.A Text book of Industrial Microbiology. Corporation. Industrial Microbiology : An Introduction. Neil L . Prestt and Dunn. . 3. Biotechnology . Delhi.2 questions A and B of l5 marks from module II with choice to answer any one QIV . 2 from each module. Industrial. Replika Press. New Age International..S.Morgan et al.B. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. C. QV . Black Well Science. Moorray-Mu-Youtig. II ELBS. one component transferred . McGraw Hill. heat. McCabe. Geankoplis C J .multi component systems.continuous contact equipment . Absorption .single stage operation . E. Reference 1.equilibrium solubility of gases in liquids .types of solid diffusion .methods of calculation.in laminar flow .drying operations .equipment and flow sheets . SinithC. Coulson J. and Harriot P.batch crying .liquid equilibria . Unit operations in Chemical Engineering. Ltd..Ponchonsavarit and McCabe -Thiele methods.. Internal work assessment Assignments (minimum 2) 2x7.types of driers. Prentice Hall India Pvt. Diffusion in solids ficks law .J. extractors – differential continuous contact extractors.unsteady state operation . Module III Drying . Chemical Engineering. Mass Transfer operations.Transport process and unit operations.mass transfer co-efficiencies .steady state continuous operation .multistage tray towers . Pergamon.stage type. Packed towers .ion exchange principles. . and momentum transfer analogies. McGrow Hill.equiibria .stages.. 2. .mult: component system .mechanism of batch drying continuous drying .L.inter phase mass transfer . Module II Liquid extraction . Leaching . M.diffusion between phases . Vol. Treybal R.steady state modular diffusion in fluids at rest and in laminar flow momentum and heart transfer in laminar flow .49 BT04 502 : MASS TRASFER AND SEPARTION PROCESSES 3 hours lecture and 1 hour tutorial per week Module I Molecular diffusion in fluids . Module IV Distillation .5 = 15 .flash vaporization. differential or simple distillation – continuous rectification binary system .mixtures of liquids .equilibrium .& Richardson J.in turbulent flow.counter current multistage operation.adsorption operation stage wise operation continuous contact . W. Mass.equilibrium .vapour liquid equilibria . Text Book 1. Adsorption .material balances .stage wise contact . material balance .one component transferred.low pressure distillation.single gases and vapours .F. 3. . Oxford University Press. QIII.processed pseudegenes catalytic RNA Transposons. Garland Publishing. QV .transcription in mitochondria and chloroplast.cis splicing and trans splicing reactions .chromosome theory of inheritance -genome size and evolutionary complexity – the structure of bacterial and eukaryotic chromosomes .role of sigma factor .RNA polymerase .represser/inducer complex catabolite repression attenuatiert Regulation of transcription . modifications of proteins. Structure of t-RNA .5 = 15 . QIV. BT04 503: MOLECULAR BIOLOGY 3 hours lecture and 1 hour tutorial per week Module I General features of chromosomes . Jones and Bartletf Publishers Inc.2 questions A and B of 15 marks from module IV with choice to answer any one.homeodomains demethylation. of ribosomes in protein synthesis regulation of translation in prokaryotes and eukaryotes .New York Bruce Alberts and James D. Module IV The operon positive and negative control of transcription .linkage and recombination of genes in a chromosome -histones – chromatin structure. 2 from each module.eukaryotic RNA polymerases -downstream and upstream promoters ~ factors of transcription . Concept of the regulation of gene expression by hormones Text 1.2 questions A and B of l5 marks from module II with choice to answer any one.DNA binding domains .pest transiational. Internal work assessment Assignments (minimum 2) 2x7.Initiation of transcription .repetitive and nonrepetitive DNA .8 Short type questions of 5 marks.super coiling and periodicity in DNA Module II Origin of DNA replication .Transcription .enhancers . Structure of DNA . Oxford .elongation and termination of transcription. Nuclear splicing .50 2 tests Regularity Total marks 2x15 = 30 = 05 = 50 University examination Pattern Q1 .promoter recognition. retroviruses and retroposons – life cycle of phages.mechanism of DNA replication and its regulation Excision repair and SOS response. QII-2 questions A and B of 15 marks from module I with choice to answer any one. Mutations in DNA.C value paradox.2 questions A and B of 15 marks from module III with choice to answer any one. Characteristics of gene mutation. Gene expression in eukaryotes . Module III Gene expression in prokaryotes . initiation . 2 3.tRNA as adapter . Benjamin Lewin: Genes VI. / Reference Books: Freibler D 'Molecular Biology.Watson : Molecular Biology of the Cell.DNA as the genetic material ..Lariat formation .role.turn over of messenger RNA . development of enzymatic assays. Internal work assessment Assignments (minimum 2) 2x7. 3. Enzyme biosensors: Applications of enzymes in analysis. Zubay G.. health care and environment.2 questions A and B of 15 marks from module III with choice to answer any one.Formulation of dimensionless groups and calculation of Effectiveness Factors.5 = 15 . Protein Immooblisation-fundamentals and applications.2 questions A and B of 15 marks from module I with choice to answer any one.51 2 tests Regularity Total marks 2x15 = 30 = 05 = 50 University examination Pattern QI . Purification and characterization of enzymes from natural sources: Production and Purification of Crude Enzyme extracts from plant. F. encapsulation. Module III: Enzyme Immobilization: Physical and Chemical techniques for enzyme immobilization adsorption. pharmaceutical and other industries.estimation of Michaelis-Menten parameters Multi-substrate reactions .2 questions A and B of l5 marks from module IV with choice to answer any one. .methods of characterization of enzymes . QIII. matrix entrapment. W. calculations in free enzyme CSTRs and immobilized enzyme reactors.Kinetics of single substrate reactions turnover number . covalent binding etc. QII .advantages and disadvantages of different immobilization techniques'. cross-linking. Tailer. QIV. Fluidized.8 Short type questions of 5 marks.Concept of active site and energetics of enzyme substrate complex formation – Specificity of enzyme action . Biochemistry. References: 1. R.Types of Inhibition kinetic models Substrate and Product Inhibition – Allosteric regulation of enzymes .mechanisms and kinetics .bed and Membrane reactors – Bioconversion.Design of enzyme electrodes and their application as biosensors in industry. BT04 504: ENZYME ENGINEERING & TECHNOLOGY (Common with AI04 504) 3 hours lecture and 1 hour tutorial per week Module 1: Applications of enzymes: Classification of Enzymes. Enzymes for analytical and diagnostic applications. Gerharts. Mass transfer effects in immobilized enzyme systems: Analysis of Film and Pore Diffusion Effects on Kinetics of Immobilized Enzyme Reactions . animal and microbial sourcessome case studies.Deactivation kinetics. examples . Module II: Mechanisms and Kinetics of enzyme action: Machanisms of Enzyme action . Enzymes in Industry-Production and Application.2 questions A and B of 15 marks from module II with choice to answer anyone. Maxwell Macmillan International Editions. Module IV: Design of enzyme reactors for bioconversion processes: Design of Immobilized Enzyme "Reactors-Packed-bed.overview of applications of immobilized enzyme systems. 2 from each module. Commercial applications of enzymes in food. 2. QV . physical properties of catalyst. Kinetics of Homogeneous reactions . BT04 505: CHEMICAL REACTION ENGINEERING 3 hours lecture and I hour tutorial per week Module I Basics of kinetics: Introduction. classification and preparation of catalyst. catalyst poisoning. Multiple reactions . Rate expressions for heterogeneous catalytic reactions. 2 from each module.2 questions A and B of 15 marks from module III with choice to answer any one. .M.2 questions A and B of 15 marks from module III with choice to answer any one.8 Short type questions of 5 marks. Scott Fogler.2 questions A and B of 15 marks from module II with choice to answer any one.2 questions A and B of 15 marks from module IV with choice to answer anyone. 3. References 1. QIII.5 2x15 = = = = 15 30 05 50 University examination Pattern QI . 2 H. Module IV: Heterogeneous catalysis Nature of catalysis.52 2 tests Regularity Total marks 2x15 = 30 = 05 = 50 University examination Pattern Q1 .Single reactor and multiple reactor design . Smith. QII . Non-ideal flow .2 questions A and B of 15 marks from module l with choice to answer any one. . 2 from each module. QV .2 questions A and B of 15 marks from module l with choice to answer any one. QV . Module III: Non Isothermal reactors and pressure effects. Kinetics of fluid-solid catalytic reactions: Adsorption phenomena. BET isotherm.2questions A and B of 15 marks from module II with choice to answer any one. Elements of Chemical Reaction Engineering. QIV . Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. series and series-parallel. catalytic specificity. Mc Graw Hill.parallel.Non-ideal flow models and reactor performance.Batch reactor analysis (integral and differential methods) for kinetics. Chemical Engineering Kinetics. Prentice Kali India Pvt. QIII .Arrhenius equation . John Wiley.8 short type questions of 5 marks. J. Octave Levenspiel .Design Principles.Chemical Reaction Engineering.searching for mechanism . Ltd. Langmuir equation. QII . QIV .2 questions A and B of 15 marks from module IV with choice to answer anyone. Module II Reactor Design: Introduction to reactor design Ideal reactors . Class A. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. 2 from each module.5 2x15 = = = = 15 30 05 50 University examination Pattern Q1 . operation and characteristics Special semiconductor devices . -Transistor oscillators.Work function . K. QII ..applications.Oscillators . QIV.OrAmp as buffer.Astable. Chand 2 Mithal G..8 Short type questions of 5 marks. McGraw Hill.Description of simple CRO tubes Structure of semiconductor materials . industrial Electronics.Bistable..Application with emphasis on chemical process-Ultrasonics. Electronics Principles & Techniques.M. 3. & Bashe C.Basic principles.Different types of amplifiers . Module III: Multivibrators . B.Dielectric properties of materials .FETSCR-LED-LCD .Power sources for induction heating . differentiator & difference amplifier . . McGraw Hill 4. Module IV: Industrial electronics-Induction heating-Principle of induction Heating . Theory & Application of Industrial Electronics. QIII-2quesIiorisAandBofl5rnarksrrommodulelIwith choice to answer any one.J.P-type & N-type semiconductors . actable and monostable multivibrators using transistors -OP-Arrp . Module II: Principle of rectification and amplification . S. C.Electrodes used in dielectric heating .53 BT04 506: APPLIED ELECTRONICS 3 hours lecture and I hour tutorial per week Module I Basic electronics .RC & transformer coupled amplifiers . Grob B.VI characteristics.Energy band diagram .Dielectric heating. Khanna Pub. Basic Electronics.Principles and operations Reference Books: 1 Ramabhadran S. Cage J..Construction.2 questions A and B of l5 marks from module III with choice to answer any one. summer. integrator. monostable & schmitt trigger using OP-Amp. voltage and current feedback amplifiers .Applications .2 questions A and B of 15 marks from module I with choice to answer anyone.Junction diodes Transistors .Instrumentation amplifier: . Heat .Principles of leeching from leaching a mixture of salt and sand. Ternary liquid equilibrium Adsorption isotherms Kinetics of chemical reaction in batch reactors. Frequency response of first and second order Reactors. 3. through pipe. Verification Distillation. Heater 2. 11. 13. tubular flow and stirred tank Open loop response of a two link liquid level system. Internal work assessment Regular work and record Test Regularity Total marks = 25 = 20 = 05 = 50 .54 QV. Vaporization efficiency in steam distillation Drying . 12. of material balance equation and Rayleigh's equation for simple transfer from steam to air . 6.2 questions A and B of 15 marks from module IV with choice to answer any one BT04 507(P): CHEMICAL ENGINEERING LAB II 3 hours practical per week 1. 10. 4. Determination of overall heat transfer coefficient by radiation to water flowing Study of long tube evaporator.rate of drying curve under constant drying condition . 7. 5.determination of heat transfer efficiency.Determination ox overall heat transfer coefficient. 8. Leaching . 9. Isolation 5. 7.55 BT04 508(P): MOLECULAR 1. 12. Restriction mapping of plasmid Gel electrophoretic separation of electroprioretic separation of RNA. Gel extraction of DNA. Gel 9. Isolation of RNA from eukaryotic of proteins from eukaryctic cells. 3. coli Internal work assessment Regular work and record Test = 25 = 20 . Gel 10. E. of genornic DNA from prokaryotic cells of plasmid DNA from prokaryotic cells. Isolation BIOLOGY LAB 3 hours practical per week of genomic DNA from eukaryotic cells. DNA and molecular weight determination 8. Isolation 6. 13. DNA. cells. electrophoretic separation of proteins Transblot analysis of DNA. 11. PCR amplification of DNA Conjugation and transformation in 2. Isolation 4. planning .single stage decision making under risk – multistage decision makingV decision tree .value .capital and capital formation .minimax and maximin criteria.types of elasticity .directing .law of demand .measurement -' its significance . Module III (13 Hours) Principles of management .span of control .relation between economic decision and technical decision .management functions . Module I (13 hours): Definition of economics .equally likely.'supply schedule .leadership and motivation .controlling decision making .Operation management .decision making under uncertainty .supply curve .market price and normal price . Module II (13 Hours) Demand .demand schedule .supply . scope of managerial economics .organising .utility .its characteristics and classification .monopolistic competition.law of supply elasticity of supply..production systems and functions .product design and .consumption – wants .elasticity of demand .time element to the determination of value .monopoly .perfect competition .56 Regularity Total marks = 05 = 50 SIXTH SEMESTER BM04 601: ENGINEERING ECONOMICS & PRINCIPLES OF MANAGEMENT 3 hours lecture and 1 hour tutorial per week Objective: The first par of this paper provides the fundamental ideas on economics an engineer to have.factors determining elasticity .basic terms and. The second part provides the basic principles of engineering management.delegation .wealth .factors of production .its peculiarities and division of labour.organisation or enterprise -economies of large and small scale .law of diminishing marginal utility .organisation structures .labour .demand curve .goods .economic efficiency and technical efficiency.nature and.nature and scope of economic science . concepts .land -' its peculiarities . Assignments/Term Project/ any other mode decided by the teacher.cost sheet .break-even analysis depreciation . 9000 system of standards of supply chain management – Project management . 10% .57 selection concepts Network crashing .market research – advertising and sales promotion – human resource management .recruitment and training -job analysis . 2 from each module QII .concept of time value of money – basics of financial accounting .concept of market and marketing .significance and methods of depreciation Internal work assessment: 60% .2 questions A and B of 15 marks from module HI with choice to answer any one Q V .marketing function .manpower requirement analysis . Module IV (13 Hours) Marketing management .costing .Test Papers (Minimum 2) 30% .2 questions A and B of 15 marks from module II with choice to answer any one Q IV. .balance -sheet .Project and management – analysis – critical path method (CPM) Network .profit and loss account .marketing mix .PERT network.2 questions A and B of 15 marks from module IV with choice to answer any one.Other measures like regularity and participation in class Total Marks = 50 University examination Pattern: Q I .concept of total quality management and ISO.2 questions A and B of 15 marks from module I with choice to answer any one Q III.8 short type questions of 5 marks.objectives/functions .allocation of overheads . Financial management .job evaluation – wages and Incentives.elements of costs' .finding critical path slacks (time cost trade off) . 2. Module III General principles of process control: Basic control elements . ratio.transducers.Bourdon gauge . Module IV Control systems: Different modes of control and their basic characteristics . Liquid level measurements in open and pressure vessels Measurement of viscosity. Introduction to advanced control techniques as feed forward feedback.piping and instrumentation diagrams. cascade.resistance thermometers thermistors .indicating and recording means .bellows . Kerk F W et al: instrumentation. Flow Measurement: Use of obstruction type meters .measuring and transmission methods . Wiley & sons . Wiley eastern Ltd. Instrumentation and control of bioreactors and fermentor Text / Reference 1.variable area meter .process characteristics Optimization of control system response .degree of freedom and fixing of control parameters.distributed and lump parameter systems .pressure probe and positive displacement type meters.58 BT04 602: INSTRUMENTATION AND PROCESS CONTROL 3 hours lecture and 1 hour tutorial per week Module I: Functions and elements of instruments .type gauge and vacuum measuring instruments. Simple system analysis . adaptive and digital computer control.optical and radiation pyrometers. Module II Pressure Measurement: Working principle of manometers . Eckman D F: Industrial Instrumentation.controller characteristics .dead time. First and higher order systems.Laplace transforms and transfer functions block diagrams – linearization.interacting and non-interacting systems .static and dynamic characteristics of instruments sensing elements .stability analysis. Temperature Measurement: Working principle of thermocouple . conductivity and pH. 2 questions A and B of 15 marks from module III with choice to answer any one QV . Module II. Bioreactor Scale-up: Regime analysis of bioreactor processes .Oxygen requirements of microbial cultures. McGrraw Hill Kogakusha.Modelling of recombinant bacterial cultures . Factors affecting oxygen transfer coefficient.Tanks-in-series and Dispersion models applications to-design of continuous sterilisers – Design and operation of novel bioreactors Air-lift loop reactors .Stability analysis of bioreactors. Heinemann Education Co. Oxygen mass transfer fundamentals. Oxygen transfer and oxygen demand.Methods of on-line and off-line biomass estimation .2 questions A and B of 15 marks from m module IV with choice to answer any one BT04 603: BIOPROCESS ENGINEERING 3 hours lecture and 1 hour tutorial per week Module I Design and Analysis of Bioreactors: Modelling of Non-Ideal Behavior hi Bioreactors .5 2x15 = = = = 15 30 05 50 University examination Pattern Q1 .Correlations for oxygen transfer. QII. Module III Modern biotechnological processes.guidelines for choosing host vector. Recombinant cell culture processes . Scale-up criteria for bioreactors based on oxygen transfer and power consumption.limits to over expression . Oxygen transfer by aeration and agitation.State and parameter estimation techniques for biochemical processes. 4. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.Bioreactor strategies for maximising product formation -Bioprocess design considerations for plant and animal cell cultures. 2 from each module.59 3. systems -plasmid stability hi recombinant cell culture .microbial calorimetry .Fluiaized-bed bioreactors . Module IV .2 questions A and B of 15 marks from module I with choice to answer any one. D R Ccughnowerand L B Koppel: Process system analysis and control..8 Short type questions of 5 marks. Monitoring of Bioprocess: On-line data analysis for measurement of important physicochemical and biochemical parameters . Determination of oxygen transfer coefficient by various methods like sulphite oxidation.Flow injection analysis for measurement of starters. products and other metabolites .2 questions A and B of 15 marks from module II with choice to answer any one QIV . QIII. dynamic gassing out and oxygen balance methecs. A Pollard: Process Control for Chemical and Allied Industries. Black well Scientific Publications. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. Principles of Fermentation Technology. Ollis.. transgenic animals.ligation of cohesive and blunt ended terminal -linkers and adapters.8 short type questions of 5 marks. Application of recombinant DNA technology: Cloning. and Maniatis. Prentice Hall.Labview Software. Biochemical Engineering Fundamentals. 1. QIV. An Introduction to Genetic engineering. Principals of Gene manipulation. and ISIM software packages. Shule Baiely Stanbury and and Kargi. Bioprocess 'Engineering.Model simulation 'using MATLAB-SIMULINK. Molecular cloning -a Laboratory Manual. Fritsch.homopolymer tailing -. P.Generation of DNA fragments by restriction endonuclease digestion . QV . endonucleases. QII. J.2 questions A and B of 15 marks from module l with choice to answer anyone. QIII. 2. ligases.joining of DNA molecules .method of creating recombinant DN A molecules Module II Basic tools of genetic engineering: Restriction. McGraw Hill 3. Computer-based data acquisition.5 2x15 = = = = 15 30 05 50 University examination Pattern QI .elucidation of the genetic code . F.. modifying enzymes Restriction enzymes and mapping of DNA. Module IV c-DNA synthesis -Construction of genomic and cDNA libraries . 2 from each module.60 Study of Structured Models for analysis of various bioprocess . E. Ti plasmid of agrobacteria. 3. Cold Spring Harbor laboratory Press.F.methods of nucleic acid sequencing. .vector design Module III Construction of recombinant DNA by various methods . Sambrook. References: 1. expression of cloned genes.2 questions A and B of 15 marks from module IV with choice to answer anyone. References: Old RW.genetic elements that control gene expression . BT04 604 : GENETIC ENGINEERING 3 hours lecture and 1 hour tutorial per week Module I Role of genes within ells . and Whitaker A. plasmid and phage vectors . T. Primrose SB.2 questions A and B of 15 marks from module II with choice to answer any one. Cloning vectors: salient features of vectors. monitoring and control .2 questions A and B of 15 marks from module III with choice to answer anyone. 2. in plants. QII. 2 from each module.post translational modifications.2 questions A and B of 15 marks from module IV with choice to answer anyone.prediction and determination of super secondary structures . QIV. principles and examples. QIII. Protein Engineering.5 2x15 = = = = 15 30 05 50 University examination Pattern QI . Module IV Protein engineering and Protein Design: Protein data base analysis – methods to alter primary structure of proteins – Examples of engineered proteins – Protein design. Module II Structure function relationship of Proteins: DNA binding proteins .DNA polumerases – Membrane proteins and receptors bacteriordopsin phtotosynthetic centres epidermal growth factor .secondary structure .tertiary structure and domain in proteins .2 questions A and B of 15 marks from module III with choice to answer anyone.prokaryotic and eukaryotic transcription factors . 2. .8 short type questions of 5 marks.2 questions A and B of 15 marks from module II with choice to answer any one. IRL Press.2 questions A and B of 15 marks from module l with choice to answer anyone. oxford. its determination . and AJ Wilkinson. Creighton TE Proteins.insulin and PDGP receptors and their interaction with effectors. BT04 605 : PROTEIN ENGINEERING 3 hours lecture and 1 hour tutorial per week Module I Primary structure and.ribonuclease – lyzozyme.Nucleotide binding protiens – enzyme serine proteases .protein folding pathways . Freeman WH.quaternary structure . QV .methods to determine tertiary and quaternary structures . Module III Protein phosphorylation – immunoglobulins . Moody PCE.61 Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. Reference: 1. .62 Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. Scoring Matrix. to transcribe and translate nucleotide sequences).Scope and history of bioinformatics — Internet basics. Fhylogenetic Software. QIII. Clustal W. QV. QIV. protocols . BIOPERL (Programme. . Module III Sequence alignment. DNA Mapping and sequencing . BLOSUM.FTP . issues in database search.HTTP. Phylip.BLAST. 2 from each module QII.NCBI.2 questions A and B of 15 marks from module I with choice to answer any one.8 short type questions of 5 marks. Elementary commands in UNIX. Sakura Database search .2 questions A and B of 15 marks from module III with choice to answer any one. BT04 606: BIOINFORMATICS 3 hours lecture and 1 hour tutorial per week Module I What is bioinformatics .5 2x15 = = = = 15 30 05 50 University examination Pattern QI . Biological databases and their use. SRS. ture database . Module II Introduction to databases. Algorithms. Phylogenetic analysis. Bankit. Sequence submission.PDB. Pairwise alignmen Dynamic programming. Methods of MSA. Gene predictions. Maximum likelihood.Distance.Map alignment Shotgun DNA sequencing .different methods cof protein structure prediction. Protein -structure prediction . Prccustes. Sequin.2 questions A and B of 15 marks from module II with choice to answer any one. www. Grail.2 questions A and B of 15 marks from module IV with choice to answer any one.Enterz. Parsimony.-PAM.Sequence assembly. Database search . Module IV Special topics in bloinformattcs. Tree building methods. Multiple sequence alignment.Telnet . Introduction to PERL (Basic commands. pattern and string matching). Sequential database .FASTA . Genscan. 3. effect of pH and temperature on enzyme activity. Enzyme Kinetics. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks Andreas D.63 Reference: 1. Estimation of Michaelis menton. Production of secondary metabolites and assay.2 questions A and B of 15 marks from module III with choice to answer any one Q V . 7. Isolation of microbes for the production of antibiotics. 2 from each module QII . Production of citric acid and alcohol and their estimation. Enzyme immobilization. Estimation of biomass. Dan Gusfield. 8. 5. parameters. 2x7. kinetics of inhibition. 6. Bioinformatics. Baxevanis. Wiley.8 short type questions of 5 marks. Antibiotics sensitivity test against common microbes 2. D. 3. Internal work assessment Regular work and record = 25 . Bioinform'atics Sequence Analysis. 2.5 2x15 = = = = 15 30 05 50 University Examination Pattern QI . 4. B. Enzyme isolation and assay.2 questions A and B of 15 marks from module II with choice to answer any one Q IV . Growth of micro-organisms and estimation of monod parameters. Francis Ouellette. 9. F.2 questions A and B of 15 marks from module I with choice to answer any one Q III.2 questions A and B of 15 marks from module IV with choice to answer any one BT04 607(P): BIOPROCESS TECHNOLOGY LAB I 3 hours practical per week 1. Algorithms on Strings Trees and Sequences. Mount. Cambridge University Press. Cold Spring Harbor Laboratory. the assessment may be made individually and in groups Internal work assessment Design Attendance Report Total Marks = 25 = 10 = 15 = 50 .a report is to be submitted at the end of the semester .64 Test Regularity Total marks = 20 = 05 = 50 BT04 608(F): MINI PROJECT 3 hours practical per week Each student group (not more than 5 members in a group) is expected to complete a mini project on a current topic of bictechnology . post cutting-strategies . Economics of downstream processing in biotechnology .classification and range of membrane systems -molecular weight cut off.types. Module II Primary Separations and Recovery Processes: Cell disruption methods for intracellular products . Module III Enrichment operations Membrane based separations .problems and requirements of bioproduct purification.role and importance of downstream processing in biotechnological processes . low-value products and low volume.characteristics of biotechnological mixtures – process design criteria for various classes of bioproducts (high volume.biomass (and particulate. high value products .removal of insolubles .membrane characteristics (rejection factor.physiochemical basis of bioseparation processes.centrifugation and filtration methods. of membranes and manufacture (isotropic and anisotropic) module types and their advantages (flat plate/hollow tube/spiral wound etc) modes of operation (cross flow and dead end)micro and ultra filitration theory . concentration .debris) separation techniques –flocculation and sedimentation .65 SEVENTH BT04 701: SEMESTER DOWN STREAM PROCESSING 3 hours lecture and 1 hour tutorial per week Module I Role of downstream processing in biotechnology . Separation process in Biotechnology. Van Deemier equation and band broadening. 2. chromatographic theory retention time and factor-selectivity factor) plate model and rate theory. Typical liquid chromatographic set up principles and working of ion exchange chromatography / adsorption chromatography / partition chromatography and affinity / chromatography.66 polarization) gel concentration model . QV .2 questions A and B of 15 marks from module III with choice to answer any one. QIV. Reference: 1. QIII. super critical extraction) . Marcel Dekker Inc.solvents and polymers. Module IV Classification of chromotographic separations.industrial applications of membrane systemsPrecipitation methods (with salts. Asenjo J. dialysis and crystallization. QII . organic. Electrophoretic separations (isoelectric focusing /gel electrophoresis /native and SDS page/southern and western blot techniques/capillary electrophoresis) Hybrid separation technologies (membrane chromatography and electro chromatography) Product polishing gel permeation chromatography.2 questions A and B of 15 marks from module I with choice to answer any one.integrated bioprocessing.2 questions A and B of 15 marks from module II with choice to answer anyone. M.A and Cussler E. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. 2 from each module. Belter P. aqueous two phase extraction.5 2x15 = = = = 15 30 05 50 University examination Pattern Q l -8 Short type questions of 5 marks. BIOTOL series VCH. Wiley. extractive separations.basic design and configuration of membrane systems (batch and multi state) .in situ product removal . .fouling and its prevention. Bioseprations. 3.2 questions A and B of 15 marks from module IV with choice to answer any one. Product Recovery in Bioprocess Technology. Cost factors in capital investment . support for vessels. cost indices: engineering news -record construction . Module IV Capital requirements and cost of production for process plants .Equipment for process plants. sum-of-digits method and units of production method . declining balance method.equations used in economic anlysis – compound . Module II Detailed process design of sell and tube heat exchangers.Time value of money and equivalence .order of magnitude estimate. sinking fund method. definitive estimate and detailed estimate. openings and reinforcements. evaporators.cost index . double declining balance method.William's six-tenth factor Capital requirements .Hoskold's formula. design of tall vessels.Fixed capital investment and working capital estimation of capital investment . . method of determining depreciation . Module III Equivalence and cost comparison .Types of capital cost estimates . Depreciation and taxes .67 BT04 702: BIOROCESS PLAN T DESIGN 3 hours lecture and 1 hour tutorial per week Module I Mechanical design of process equipment .taxes and depreciation.and closures nozzles. declining balance method.Introduction to the design of cylindrical and spherical vessels for internal and external pressures.interest as operator — unacost . absorbers and distillation columns.material cost indices. design of heads . Balance sheet and profit and .straight line method. labourcost index equipment costs .Nature of depreciation.direct and indirect costs .Estimation of total product cost. Chemical Engineering Economics and Decision Analysis. 7. and Chilton (Ed. plant design and economics for chemical engineers. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. Process Equipment Design.5 2x15 = = = = 15 30 05 50 University examination Pattern QI . QIII.2 questions A and B of 15 marks from module II with choice to answer anyone. Davies. 5.use of probes – RNA cDNA and DNA – nucleic acid hybridizations – southern. Peters and Timnerhaus.S. 2. Cost and Optimization engineering 3. 4. Recombinant selection and Screening. BT04 703: RECOMBINANT DNA TECHNOLOGY 3 hours lecture and 1 hour tutorial per week Module I DNA Technologies Introduction of recombinant DNA into a host (bacteria & animals by various methods) – Transformation – in Vitro packaging into phages . H. Tyler. J.C.68 loss account. northern biotting – colony and plaque hybridization – Screening immunochemical methods. Process Engineering Economics. Jelen F. cost estimation 6. Gene Modification : Mutagenesis – deletion mutagenesis – oligonucleotide directed mutagenesis –PCR based mutagenesis . Module II Expression of Cloned Genes: Salient features of prokaryotic and eukaryotic expression systems – fusion proteins – secreted proteins – in vitro gone expression .2 questions A and B of 15 marks from module III with choice to answer any one.RAGE – applications of PCR. G.Site directed mutaenesis and its applications. M. Joshi.)m.V. (Use of Chemical Engineers’ Handbook by perry and Chilon and IS 2825 : 1969 0 Code for Unfired Pressure Vessels may be permitted for the University Examinations) Reference: 1. DNA Amplification: Polymerase chain reaction (PCR) . Schweyer. QII. QIV-2 questions A and B of 15 marks from module IV with choice to answer any one. Perry.2 questions A and B of 15 marks from module I with choice to answer any one. Chemical Engineers’ Handbook. Module III DNA Sequencing: Chemical method of maxam & gilbert – enzymatic (diddeoxy chain termination) method of . Chemical engg.basic reactions – inverse PCR – RTPCR.trassfection – reporter and gene targeting. 2 questions A and B of 15 marks from module II with choice to answer any one.2 questions A and B of 15 marks from module III with choice to answer any one. novel proteins. Panima Publishing Cooperation.H. vaccines. DNA mapping and Analysis of DNA Sequences: Restriction mapping. QII . insecticides. Watsor. 2. D. sheep. Scientific American Books. Module IV Safety aspects of recombinant DNA technology.J.DNA fingerprinting – chromosome walking – chromosome jumping. QIV.69 Sanger – automated sequencing. Transgenic Technology: Transgenic mouse – transgenic fish – transgenic animals – pig.xoprecipitation – electroporation – lipofection – microinjection. rabbit.8 Short type questions of 5 marks. Pastrnek J. 2 from each module. . N. New Delhi. Freeman and Co. W.5 2x15 = = = = 15 30 05 50 University examination Pattern QI . Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.2 questions A and B of 15 marks from module I with choice to answer any one QIII. Application of r-DNA Technology: Diagnostic s – Pathogenesis – Genetic diversity – RELP analysis and DNA finger printing – Theraputic proteins. Recobinant DNA. Gene Transfer Techniques: CaFO . J. Antisense Technology and Applications Reference: 1. QV .2 questions A and B of 15 marks from module IV with choice to answer anyone. Glimath. Bernur R. Principles and Applications in Recombinant DNA. New York. Molecular Biology. antibodies herbicide resistance. strategies for accessing .biomarkers and bioreceptors Bioremediation .contaminant of biologically . Module III Waste treatment .Biological treatment of solid wastes . Module IV Downstream processing in biological waste treatment process – effluent disposal and reuse – Biofilteration for waste gas treatment — types of biogas plants and microbial processes involved in biogas generation . Microbial biodiversity .Microbiological and biochemical aspects of waste.Microbial strain improvement with a view to develop scavengers .70 BT04 704: ENVIRONMENTAL BIOTECHNOLOGY 3 Hours lecture and 1 hour tutorial per week Module I Components of environment and assessment of its quality .various types of composting processes.Factors of environmental degradation and pollution – pollutants and.Waste disposal and management .recovery by the use of environmental DNA – Extremophiles and their application Module II Environmental geaomics – Deliberate release of recombinant microorganisms .bioremediation of petroleum based wastes – Phyteremediation – bioleaching degradation of pesticides.Aerobic and anerobic waste treatment process (with examples) industrial waste – agricultural waste . polyarotnatic hydrocarbons .bioprospecting .Characteristics of waste water . herbicides.Composting and.composition and purification of biogas . treatment processes .nature and source.xenobiotics – metabolic engineering. their types .municipal waste . system engineering process .prototyping in the software process .life cycle models iteration. Ellis Horwood Ltd.economy of biological treatment process. Environmental Biotechnology. Mooray -Mu.the software process .user interface design design principles . Raina M. F.Validation.interface specification behavior specification .interface evaluation.CASE work benches.2 questions A and B of 15 marks from module IV with choice to answer any one. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.evolution .feasibility studies .application families . BT04 705 (A): SOFTWARE ENGINEERING (Common for EE. IC.objects and classes .functional and non-functional requirements . Environmental Microbiology.domain specific architectures .component-based development .user support .specification .5 2x15 = = = = 15 30 05 50 University examination Pattern QI -8 Short type questions of 5 marks. QII . ASM Press. QV .rapid prototyping techniques – formal specification .system requirements . 3. 2. Comprehensive Biotechnology.context models behavior models . 2 from each module.2 questions A and B of 15 marks from module II with choice to answer anyone.object models .requirements engineering processes .system structuring .software requirements . BM.SRS .A. Premagaon Press.automated process support .design end implementation .Young. Module III .professional and ethical responsibility system modeling .architectural design .71 toxic wastes .design patterns .real-time executives – design with reuse . QIII.2 questions A and B of 15 marks module III with choice to answer any one. John Ware D.an object oriented design process case study design evolution . PM) 3 hours lecture and 1 hour tutorial per week Module I Introduction . Mayer.elicitation and analysis .management system models . QIV .FAQs about software engineering ..formal specification in the software process .validation .system design . Foster C.real-time software design . Module – II Software prototyping .2 questions A and B of 15 marks from module I with choice to answer any one. Reference: 1..information presentation .distributed systems architecture – objectoriented design .control models – modular decompositions .user interaction .data models .user requirements . AI. 2 from each module.quality planning .. & Hudson F.security .critical system development ..process CMM configuration management .2 questions A and B of 15 marks from module IV with choice to answer any one.software re-engineering .productivity estimation techniques . S. software Engineering.architectural evolution . Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.software testing . Narosa. Text Book: 1. Pressman R.. Fundamentals of Sftware Engineering Prentice Hall of India. Pearson Education Asia Reference Book: 1.object-oriented testing .process analysis and modeling . 4.planning software inspection .. Oxford University Press.managing people . QII .testing workbenches critical system validation -software evolution . project duration and staffing quality management .2 questions A and B of 15 marks from module I with choice to answer any one.quality assurance and standards .process measurement .CASE tools for configuration management. Ian Sommeerville.project planning .clean room software development .integration testing . J.process and product quality .automated static analysis .choosing and keeping people . QIV .planning .verification and validation .quality control -software measurement and metrics -process improvement .2 questions A and B of 15 marks module III with choice to answer any one. QV . Software Engineering.software maintenance .72 Dependability .legacy systems .5 2x15 = = = = 15 30 05 50 University examination Pattern Q 1 . QIII. Mali R. . An Integrated Approach to s\Software Engineering.change management .group working .the people capability maturity model software cost estimation ..critical systems specifications .software change .data re-engineering Module IV Software project management . Jalote P.version and release management system building . McGraw Hill.defect testing .scheduling .2 questions A and B of 15 marks from module II with choice to answer anyone.availability and reliability . Software Engineering Fundamentals.critical systems . Benferooz A.8 Short type questions of 5 marks.algorithmic cost modeling. 2. 3.safety .risk management . activity – activity coefficients – Properties of solutin . Module II Phase equilibra – Nature of equilibrium – Criteria of equilibrium – fugacity – calculation of fugacity. .partial molar properties .Ideal solution – Non ideal solutions .Wohl’s equations – Van-larr equation. Thermodynamics of flow processes – single stage and multi stage compression .Joule Thomson expansion .Gibbs phase rule .hear capacity in terms of entropy – systematic derivation of thermodynamic relations – effect of pressure and volume on heat capacities – the coefficient of expansion and isothermal compressibility coefficients .Fugacity as a criterion of equilibrium – Vapour liquid phases in equilibrium – binary solutions .construction of thermodynamic charts.flow through nozzles and ejectors.chemical potential .73 BT04 705 (B) : CHEMICAL ENGINEERING THERMODYNAMICS 3 hours lecture and 1 hour tutorial per week Module I Thermodynamic PROPERTIES Of fluids – Reference properties – Energy properties – derived properties – path properties .Maxwell relations – heat capacity relations . Module III Vapour liquid equilibrium at low pressure – Equality of chemical potentials .?Giibbs Duhem equation Enthalpy and entropy of solution. Module III New and modified carbohydrates. Role of micro organisms in manufacture and spoilage of fermented products.8 Short type questions of 5 marks.74 Refrigeration – Carnot refrigeration cycle – air refrigeration cycle . milk.5 2x15 = = = = 15 30 05 50 University examination Pattern Q I . QV . proteins and nucleotides – New protein foods : SCP mush room food yeasts algal protein – production of microbial biomass and economic aspects – probiotics. Module IV Genetically modified and transfeneic food development processing . chemical Engineering thermodynamics. 2 from each module. Pilot and large-scale fermentation.2 questions A and B of 15 marks from module IV with choice to answer any one. Module IV Chemical reactions equilibria .2 questions A and B of 15 marks module III with choice to answer any one. Narayanan. 2. S. QIV .2 questions A and B of 15 marks from module II with choice to answer anyone. . flavours. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. Fruits. Module II Biotechnological processes in conventional and non-conventional fermentation – secondary fermentation of waste generated in selected food fermentation. vegetables. Adulteration in foods .2 questions A and B of 15 marks from module I with choice to answer any one. 3.vapour compression cycle – choice of refrigerant absorption refrigeration. any vitamins.milk. fish and meat. . Reference Books 1. Smith Vnness and Abott. BT04 705(C): FOOD BIOTECHNOLOGY 3 hours lecture and 1 hour tutorial per week Module I Technology of conventional and non-conventional fermentation based food products from cereals.the equilibrium constant – evaluation of equilibrium constant from thermal data effect of temperature and pressure on equilibrium constant. QII .nutriotion and aspect – Protein engineering in food biotechnology – Biotechnology of food preservation – Genomics for food biotechnology – Food biotechnology additives like colors. K. Introduction to Chemical engineering Thermodynamics.feasibility of chemical reaction – presentation of free energy data – calculation of free energy of reactin . Sandler. lipids. continuous and batch culture process monitoring and control. QIII. pulses and others. V. polysaccharides.Free energy and chemical reactions . Chemical Engineering Thermodynamics. Jugumes. extreme points fundamental theorem of linear programming. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. 2 from each module.optimality conditions unbounded solutions .2 questions A and B of 15 marks from module IV with choice to answer any one.stepping stone algorithm .dominance . linear programming.reduction of a feasible solution to basic feasible solution . assignment and game problems and queing theory Module I: Linear Algebra (13 hours) Vectors .coefficient matrix and its properties .2 questions A and B of 15 marks from module II with choice to answer anyone. Stanbury P.2 questions A and B of 15 marks from module I with choice to answer any one. Gorden B. Module III: Transportation.simultaneous equations .vector space and Euclidean space .75 Reference Books 1.degeneracy in transportation problems – assignment problem as a maximally degenerate transportation problem . Challenges for the flavour and food industries.birth and death .UV method inequality constraints . Willis..graphical solutions.rank . Roger A.basic feasible solutions .rectangular zero sum games – von Neuman's theorem .spanning set .tableau format .lines and hyper planes . 2. F. and John T. transportation..5 2x15 = = = = 15 30 05 50 University examination Pattern Q I .vector operations . Module 1V: Queuing (13 hours) Basic structure of queuing models .Koning's method ..basic set of column vectors linear combination of basic vectors . Biotechnology.2 questions A and B of 15 marks module III with choice to answer any one. BT04 705 (D) : OPERATIONS RESEARCH 3 hours lecture and 1 hour tutorial per week Objective To provIde knowledge en Linear algebra. Module II: Linear Programming (13 hours) Statement of the LP problem . Pergamon Press. QIV .exponential and Poisson distributions . QIII. QII .unit vector sum vector . Principles of Fermentation Technology.linear inequalities .matrix operations .convex sets .linear dependence bases . Food Biotechnology. 3.Chames' M method .basic solutions .8 Short type questions of 5 marks.formulation of the primal and dual LP problem for fixed strategies . Lindsay. and Whnaker A.slack and surplus variables . Assignment and Game problems (13 hours) Transportation problem .point sets .saddle points .pure and mixed strategies . QV .artificial variables .two phase method . Elsvier Applied Science.degeneracy – duality. Wiley Toppan 2. plant regeneratin. factors influencing disease resistance and susceptibility RFLP. role of tissue culture in rapid clonal propagation. culture and plant regeneration. Types of plant vectors and their use in gene manipulation.8 short type questions of 5 marks. Regulation of nif and nod gene – mechanism of nitrogen fixation.remedy.queuing models based on Poisson inputs and exponential service time basic model with constant welfare and service rate . Operations Research. Linear Programming. organogenesis. Symbiotic Nitrogen fixation. Hadley G. Wagner. applications of . Prentice Hall of India.2 questions A and B of 15 marks from module IV with choice to answer any one. 3. isolation. Module III Molecular aspects of disease susceptibility and resistance: Transposable elements.2 questions A and B of 15 marks from module II with choice to answer any one. QV . and fundamentals of recombinant DNA technology. Gene regulation. QIII.76 processes . protoplast fusion. Developmental aspects of rhizbbium: Legume Symbiosis. identification and characterization of somatic hybrids.2 questions A and B of 15 marks from module 1 with choice ton answer any one.Bellman's principle of optimality . Agrobacterium and plant genetic engineering: Agrobacterium mediated gene transfer and cloning. Operations Research.formulation and solution of simple problems.Viruses as a tool to deliver foreign DNA.Poisson arrival with constant service time . QIV . Operations Research: Methods and Problems. BT04 705(E) : PLANT BIOTECHNOLOGY & TISSUE CULTURE 3 Hours lecture and 1 hour tutorial per week Module I An outline of Molecular biology: DNA Replication. Ravindran. viral resistance stress tolerance development of disease resistance plants by introducing Bacillus thuringiensis genes. John Wiley. Addison Wesley 2. Protoplast technology. QII. Module IV Fundamentals of plant tissue culture. 2 from each module. Reference Books: 1. production of pathogen free plants and synthetic seeds. Yaspen .Poisson arrival and Erlang service times -priority disciplines .. translation. medium formulation. Module II Plant viruses: Classification diagnosis .limited source queue models involving non-exponential distributions .single service model with Poisson arrival and any service time distribution .2 questions A and B of l5 marks from module III with choice to answer any one. Holden Day Inc. HilHer Sc Liberman.. transcription.dynamic programming .Finite queue . Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. Text Book: 1.& Friedman. Transgenics Herbicide-tolerance insect resistance. Saskieni. Principles of Operations Research.5 2x15 = = = = 15 30 05 50 University examination Pattern QI . Solberg & Phillips. Chromatographic techniques Ultra filteration. 5. Recovery of products Extra cellular enzyme production and purification Production of intracellular products Cell disruption techniques. 3. 2 from each module. QII .A. 2. QV . Blackwell Scientic Publications. Mantal S. Dodds J . two phase aqueous extraction Product crystallization and drying. 7.H.. centrifugation.5 2x15 = = = = 15 30 05 50 University examination Pattern Q1 . Filtration. Cambridge University Press.H. Plant Genetic Engineering.2 questions A and B of 15 marks from module Il with choice to answer any one.2 questions A and B of 15 marks from module III with choice to answer any one. References: 1. Principles of Plant Biotechnology An Introduction to Genetic Engineering in plants. BT04 706(P) : BIO PROCESS TECHNOLOGY LAB (3 hours practicals per week) 1. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.2 questions A and B of l5 marks from module IV with choice to answer any one.. 2. Mathews J. 8.plant growth factors and plant growth regulators. sedimentation.8 Short type questions of 5 marks. QIV .Mickee R. QIII. 4.A. solid .77 protoplast technology .liquid separation methods..2 questions A and B of 15 marks from module I with choice to answer any one. Internal work assessment Regular work and record Test Regularity = 25 = 20 = 05 . product enrichment operations. 6. Internal Marks Allotment Presentation and Discussion Relevance of topic and Literature survey Participation in other Seminars Report Total marks = 25 marks = 10 marks = 05 marks = 20 marks = 50 marks in the field. which will be .78 Total marks = 50 BT04 707(P) : SEMINAR 4 hours per week Each student can take seminars on topics of interest assessed by the faculty members. Internal Marks Allotment Design Attendance Report Total marks = 25 marks = 10 marks = 15 marks = 50 marks .79 BT04 708 (P) : PROJECT WORK 3hours per week The project is for a duration of two semesters .an interim report is to be submitted at the end of the semester – the assessment may be made individually and in groups.the seventh semester is mainly for reference and design of experiments .each student group (not more than 5 members in a group) is expected to develop a complete Project . genetic control of antibody production .80 EIGHTH SEMESTER BT04 801 : IMMUNOLOGY & IMMUNOTECHNOLOGY 3 hours lecture and 1 hour tutorial per week Module I The Immune System : Introduction . Autoimmunity: Autoantibodies in humans – pathogenic mechanisms – experimental models of autoimmune disese treatment of autoimmune disorder.their origin arid differentiation .mono clonal antibodies and diagnosis .structure and function of immunoglobulin . Transplantation: Graft rejection – evidence and mechanisms of graft rejection – immunosuppressive drugs – HLA and disease – mechanisms of immunity to tumor antigens.complement and their biological functions Module II Humoral Immunity: B-Iymphocytes and. Module III Immunity to Infection: Hypersensitivity reactions .antigens .immune tolerance.mechanisms of T Cell activation cytokines and their role in immune response macrophage activation and granuloma formation. their activation .lymphocytes . Cellular Immunologu: Thymus derived lymphocytes (T cells) their classifications antigen presenting cells (APC) – macrophages langerhanscells – their origin and functions mechanisms of phagocytosis – identification of cell types of immune system – immunosuppression .idiotypes and idiotypic antibodies – major histocompatibility complex. .Immunoglobulin classes and subclasses .their structure and classification . Trends is Immunology of infectious diseases and tumours.Basic principles and general requirements of patents (Novelty. BT04 802 : BIOETHICS & INTELLECTUAL PROPERTY RIGHTS 3 hours lecture and 1 hour tutorial per week Module I Biotechnology and Bioethics .8 Short type questions of 5 marks.Objectives of the patent system . copyrights.Risk Assessment of rDNA products and guidelines . Ivan I.Points in maintaining laboratory notebook for an inventor Exercising and enforcing of intellectual property rights . Freeman & Company..2 questions A and B of 15 marks from module III with choice to answer any one.of intellectual property rights (trade marks. Immunological Methods manual. Immunology.Licensing agreements . Module IV . 2.Rights of IPR owner . I. Environmental Ethics.Criteria for patent infringement. Academic Press. Module II Intellectual Property Rights .What is Ethical Biotechnology? (Rights. TRIPS and other International conventions (Paris Convention. Module III Patenting process in India . K. M. Utility non obviousness etc. ELISA. industrial designs. Decision Making) .Ethical aspects of rDNA products .81 Module IV Molecular Immunology: Preparation of vaccines – application of recombinant DNA technology for the study of the immune systems – production of antidiotyoic antibodies 0 catalytic antibodies . Epitope mapping .) and Patent law . Western blot. Brostoff J.. QV . geographical indicators etc.) . Roitt.Regulations for safe development of transgenic plants. D. 2 from each module. QII .5 2x15 = = = = 15 30 05 50 University examination Pattern Q1 . Immunology Mosby Publication.Various types.Product and process patents. Confidentiality.Biosafety in rDNA research and production. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.Patent cooperation treaty -IPR and WTO regime. and male.2 questions A and B of l5 marks from module IV with choice to answer any one. Immunoelectrophoresis.2 questions A and B of 15 marks from module Il with choice to answer any one. 3. patents.2 questions A and B of 15 marks from module I with choice to answer any one. Reference Books 1. Janis Kuby. Animal Rights.application of PCR technology to produce antibodies and other immunological reagents – immunotherapy with genetically engineered antibodies. QIV . W. QIII. Radioimmunoassay. regulation — National and International guidelines . H. Budapest Treaty) -Various amendments to Patent Law in India and the US . Current topics in Immunology: Hybridoma techniques and monoclonal antibody productin – Diagnostic methods : Immunodiffusion. induction. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7. regulation in branched pathways. Rehm and G.Unleashing the knowledge Economy. limiting accumulation of end products feed back. mixed or sequential bioconversions insoluble substances. glucose effect. prophophase. 2. Module IV Regulation of enzyme production Strain selection. The patentability of microorganisms . improving fermentation. resistant mutants.Diamond vs Chakrabarty case Bioprospecting and biopiracy (case studies of neem. mutation. Prabuddha Ganguli. Module II Synthesis of primary metabolites: Alteration of feed back regulation. feed back repression. facilitated diffusion.2 questions A and B of 15 marks from module II with choice to answer any one. concerted feed back regulation. permeability control passive diffusion. recognizing growth cycle peak. metabolites.2 questions A and B of 15 marks from module I with choice to answer any one. enzyme induction. active transport group transportation. regulation. Vol. feed back regulation. Reed.8 short type questions of 5 marks. factors Important to bioconversions. Module III Bioconversions: Advantages of Bioconversions.Jacob Monod model. avoidance of product inhibition.5 2x15 = = = = 15 30 05 50 University examination Pattern QI . differential regulation by isozymes. QIII.IPR plant genetic resrouces . Biotechnology Second Edition. QIV .82 Biotechnological inventions and patent law – patentable subjects and protection in biotechnology. producers of secondary. mutants resistant to . co-metabolism. VCH Publishers. QV . Energy charge-regulation. Intellectual Property Rights . Biosynthesis of secondary metabolites: Precursor effects. Reference Books 1. energy charge. specificity yields. idiophase relationship.Plant breeder rights – UPOV treaty. Multi Volume Treatise. Amino acid regulation of RNA synhesis. catabolite regulation by passing control of secondary metabolism. J. QII . Tata Mcgraw Hill. Cumulative feed back regulation. BT04 803 : METABOLIC ENGINEERING 3 hours lecture and 1 hour Tutorial per week Module I Introduction. permeability.2 questions A and B of 15 marks from module III with choice to answer any one.options for protection of traditional knowledge systems Biodiversity and farmer rights . regulation of enzyme synthesis. catabolite regulation. 2 from each module. feed back regulation. turmeric and Basmati) – Traditional knowledge systems . camp deficiency. alteration of permeability. amino acid regulation of RNA synthesis. 12 Legal Economic and Ethical Dimensions. catabolite repression.2 questions A and B of 15 marks from module IV with choice to answer any one. Module III Molecular Therapeutic technologies.pharmaceutical Applications .New Targets for drug discovery Module IV Proteomics: Proteomic Techniques .Functional Genomes .5 2x15 = = = = 15 30 05 50 University examination Pattern QI .in human. Role of animal models in identification of genes for disorders knockout mice.L. Gehomics and Proteomics.Proteomics in drug discovery . Sahai. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.8 Short type questions of 5 marks.Human Genome Project -Genomes of other organisms . Dunnil P.2 questions A and B of 15 marks from module III with choice to answer any one. Wang D..Role of genomics in Drug discovery and development . Plenum Publications.LC.83 repression.2 questions A and B of 15 marks from module II with choice to answer any one. Functional and Computational Aspects. QII . Reference: 1. Biopharmaceutical Industry . Humphery A. QIV .Pharmacogenetics Genomics in relation to molecular diagnosis. Gene Therapy . QV . Cooney C. A.2 questions A and B of 15 marks from module l with choice to answer anyone. John Wiley and Sons.. 2 from each module. gene dosage. QIII.Genome Mapping . .peptide nucleic acid technology. Reference: 1. Fermentation and Enzyme Technology. Module II Genomics in. BT04 804(A) : GENOMICS AND PROTEOMICS 3 hours lecture and 1 hour tutorial per week Module I principles of gene Expression .2 questions A and B of 15 marks from module IV with choice to answer any one.E. Demain AL. 2 questions A and B of 15 marks from module III with choice to answer any one.8 Short type questions of 5 marks.Special Requirements for Bulk Drug Manufacture Manufacturing principles.Constant dynamics . Important unit processes and their applications Bulk drug Manufacturers. 2 from each module.Angle Bending . Action of drugs on human bodies.Time dependent properties -Molecular Dynamics as constant temperature and pressure.84 Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.Electrostatic interactions .2 questions A and B of 15 marks from module IV with choice to answer any one BT04 804(B) : MOLECULAR MODELLING AND DRUG DFESIGN 3 hours lecture and 1 hour tutorial per week Module 1 Empirical force fields molecular mechanisms : Bond Stretching .Out of plane bonding motions .Van der Waals.Molecular Dynamics with continuous potentials Running Molecular Dynamics simulation .Long range process.Practical aspects of computer simulation .Analyzing results of simulation and estimating errors. Module II: Simulation o: liquid water . radioactivity pharma kinetics.2 questions A and B of 15 marks from module l with choice to answer anyone.Torsional I terms . QIV . QIII.Computer simulation methods Calculation of thermodynamic properties . interactions Effective pair Potentials . Drug metabolism Physico chemical principles.2 questions A and B of 15 marks from module II with choice to answer any one. Module III Molecular dynamics simulation Methods:.5 2x15 = = = = 15 30 05 50 University examination Pattern QI .Hydrogen Bonding.Boundaries monitoring Equilibrium . Types of Reactions in Bulk drug Manufacture and Processes . Molecular dynamics using simple modules .Phase space . QII . QV . . QV. Longman. 'Applied Design in Chemical and Petrochemical Plants. QII . BT04 804(C) : DESIGN OF PROCESS EQUIPMENTS 3 hours lecture and 1 hour tutorial per week Module I Basic considerations in Process Equipment Design .Process Design aspects.Large capacity storage tanks.The general design procedure .Vessels operating at low and elevated temperatures – Design conditions-and stresses .Combined stresses and theories of failure .2 questions A and B of 15 marks from module IV with choice to answer anyone.Stresses in column shell – Determination of shell thickness .Structure Based methods to identity lead components – Denovo ligand design.Corrosion prevention .Nozzles and mountings .Elastic instability .Effect of fabrication methods. Types of heat exchangers .E.Pressure vessel code . . Module II Pressure Vessels – Operating conditions .Creep.2 questions A and B of 15 marks from module III with choice to answer anyone.Equipment classification – Material selection .Fatigue .Temperature effects .Heating systems.Column internal details . QIII.Stresses created due to static and dynamic loads .Thermal stresses in cylindrical shell Review-of unfired pressure. E. Ludwig. 2 from each module. A.Elastic stability. Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.Design of shell and its components Supports .2 questions A and B of 15 marks from module I with choice to answer any one.Monte Carlo or Molecular Dynamics. Reference Book 1. Reference: 1. Molecular Modelling Principles and Applications.85 Module IV Monte Carlo Simulation Methods:. Module III Design of storage tasks .Molecular docking . QIV.Fabrication techniques . Lenon.5 2x15 = = = = 15 30 05 50 University examination Pattern Q l . Metropolics methods – Monte Carlo simulation of molecules – Monte Carlo simulation o f polymers – Calculating chemical potentials .2 questions A and B of 15 marks from module II with choice to answer any one. R.Stresses from local loads and thermal gradient .Design considerations. vessel codes.Process and Mechanical Design of Shell and Tube Heat Exchangers. under compressive stresses . Classification of reaction vessels . Molecular Modelling to discover and design New Molecules: Molecular modeling in drug discovery – Deriving and using 3D Pharma cores .Radiation effects .8 Short type questions of 5 marks. Module IV Distillation and Fractionation Equipment .Allowable deflection . QIII. E. codes. Text Books 1. QIV. standards. Process Equipment Design. G.5 2x15 = = = = 15 30 05 50 Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks University examination Pattern Q l . Wells: Safety in Process Plant Design. Lees: Loss Prevention in Process Industries. 2 from each module. Hazards: Chemical.HAZOP and HAZAN – importance of risk analysis. M. P.2 questions A and B of 15 marks from module I with choice to answer any one. 3. An Introduction to Chemical Engineering Design. 2. .8 Short type questions of 5 marks. . case history. F. Module IV Designing for safety . Wiley. Module II Explosion and hazards due to chemical reaction – Identification of hazards – fire and explosion hazard rating of process plants . Joshi. mechanical and physical . 2x7.health hazard of industrial substances. Green: High Risk Technology. QII . R K Sinno. Butterworth.86 2. IchemE/Godwin. Module III Consequence analysis – Modeling of fire. L. BT4 804(D) : SAFETY IN PROCESS PLANTS 3 hours lecture and 1 hour tutorial per week Module I Origin of process hazards. explosion and toxic gas dispersion. QV.2 questions A and B of 15 marks from module IV with choice to answer anyone.2 questions A and B of 15 marks from module III with choice to answer anyone. Event probability and failure frequency analysis – individual risk and societal risk reliability and risk analysis.safety training – emergency planning and disaster management – case studies.V. A.2 questions A and B of 15 marks from module II with choice to answer any one. 3. laws. Module III Hazardous waste minimization . 2. Liu I (ed). Module II Generator requirements . and Cornwell. D..A.5 2x15 = = = = 15 30 05 50 University examination Pattern QI .87 . storage and disposal requirement .hazardous waste numbers and codes.specific and non specific sources . McGraw Hill.transporter requirements ..8 Short type questions of 5 marks.European and US Acts. QIV .deep well injection .the secures land fill . Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.2 questions A and B of 15 marks from module IV with choice to answer any one. Land disposal – land treatment .benefits – elements of programme .ground water monitoring. . QV . QIII. Environmental Engineers’ Handbook.2 questions A and B of 15 marks from module I with choice to answer any one.treatment. 2 from each module. BT04 804(E): HAZARDOUS WASTE MANAGEMENT 3 hours lecture and 1 hour tutorial per week Module 1 Classification of hazardous wastes – Hazardous waste designation system – Hazardous Waste (Management and Handling) Rules .land fill construction.Management of specific recyclable hazardous waste like precious metals lead acid batteries. QII . The hazard ranking system – prioritization of actions – contingency plans – Liabilities.Procedure and considerations . Chemical and Biological Treatment . effective waste minimization Module IV Treatment technologies . Lewis Publishers.2 questions A and B of I5 marks from module III with choice to answer anyone. Reference Books 1. L. Preparation of a waste inventory . Davis M. Introduction to Environmental Engineering.2 questions A and B of 15 marks from module II with choice to answer any one.waste audit – waste exchange – recycling.Physical. Economics of drug industry.parental solutions .direct compression . Packing .time profile .analytical methods and rest for various drugs and Pharmaceuticals.tablet presses coating of tablets. Preclinical studies.general principles.5 2x15 = = = = 15 30 05 50 University examination Pattern QI . Action of drags on human bodies. QV . Role of FDA. and metabolism (Biotransformation . Different classes of therapeutic agents .dry granulation or slugging . target of drug action. BT04 805(A) : BIOPHARMACEUTICAL TECHNOLOGY 3 hours lecture and 1 hour tutorial per week Module I Introduction: Development of Drug and Pharmaceutical Industry.their uses..8 Short type questions of 5 marks..Pharmacokinetic models . Important amendments in drugs regulation. Regulatory aspects in drag development. QIII.2 questions A and B of l5 marks from module II with choice to answer any one. GMP .Quality Management.2 questions A and B of l5 marks from module IV with choice to answer any one. Clinical trials.88 Internal work assessment Assignments (minimum 2) 2 tests Regularity Total marks 2x7.one compartment modeling. receptor theory. Physico chemical principles affecting all the above plasma drug concentration . Capsules Sustained action dosage forms . Module III Important unit processes and their application: Tablets – wet granulation .ointments . Pharmacogenomics.Packing Techniques .2 questions A and B of 15 marks from module I with choice to answer any one. QII .2 questions A and B of l5 marks from module III with choice to answer any one. 2 from each module. receptors.topical Applications – ointments preservation .oral liquids injections . distribution.phase I. QIV . II reactions) Pharmacokinetics &. Indian drugs and cosmetic act. Module II Biophamaceutics Drug absorption. pharmaecoaomics. The Organic Chemistry of Drug Design and Drug Action. Elsevier. QII .cytotoxity and viability assays – Cell cultures as sources of valuable products. Vaccines (Polio.organ culture . Lea arid Febiger.2 questions A and B of l5 marks from module III with choice to answer any one. Hormones (Human growth hormone) – Analgesics. QV.scaling up of animal cell cultures .Penicillin.5) (2 X 15) = = = = 15 30 5 50 University examination Pattern Q1 .2 questions A and B of 15 marks from module IV with choice to answer any one. 2 from each module. Pharmacology. Cloned animals Module IV Protein production by genetically engineered mammalian cell lines . 3.State of the Art. Non steroidal contraceptives.2 questions A and B of 15 marks from module I with choice to answer any one.89 Module IV Pharmaceutical production and their control Therapeutic categories such as Antibodies . BT04 805 (B) : ANIMAL BIOTECHNOLOGY 3 hours lecture l hour tutorial per week Module I Introduction: What is Animal Biotechnology and its sco[pe .preservation and characterization of animal cells . genetic recombination in mammalian cells and embryos. Theory and practice of IndustrialPharmacy.2 questions A and B of 15 marks from module II with choice to answer any one. QIV . Rang Dale Riter. Churchill Livingstone Internal work assessment Assignments Tests Regularity Total marks (2 X 7. 2. Module II Animal Cell Culture Principles of sterile techniques and cell propagation .Chemically difined and serum Free media for membrane cell culture .8 Short type questions of 5rnarks. QIII . Biologicals.insulin. Richard B.optimization of animal cells growth in bio reactors – Emission. Publications. Reference Book .animals in Biotechnology . Module III Genetic Recombination Tchniques: Mammalian genome. BDG Influenza). Leon Lachman etal. Silverman. Reference: 1. Module III Cost factors in capital investment – Purchased equipment installation – Insulation cost Instrumentation and Controls .Precommissioning – Commissioning. Panima Publishing Cooperation. Plot plan.Service facilities. bid pre-contract.5) (2 X 15) = = = = 15 30 05 50 University examination Pattern Q l .Bar chart . Engineering and Supervision – Procurement . Principles and Applications in recombinant DNA. Molecular Biology.Different types of project contracts – Scope . project report. QV~ 2 questions A and B of 15 marks from module IV with choice to answer any one BT04 805(C): PROJECT MANAGEMENT 3 hours lecture and I hour tutorial per week Module I Introduction to project management . detailed engineering man hours. Internal work assessment Assignments Tests Regularity Total marks (2 X 7. Pastrnek. 1.PERT and CPM . Cost estimation concepts.Building including services Yard improvements .Contractors’ fee – Contingencies.2 questions A and B of 15 marks from module III with choice to answer any one.Definitions and terms such as flow diagrams.2 questions A and B of 15 marks from module II with choice to answer anyone. Module II Sequence and process of preparing preliminary and final project reports and feasibility studies – Demand Analysis . 2 from each module. Module IV Planning and control . Preliminary estimation.Piping – Electric installations . .Start-up expenses .J. . J. Detailed estimation. New Delhi M. Utility.Inspection and Expediting .90 Bernur R. P and I diagram. Q1V .8 short type questions of 5 marks.2 questions A and B of l5 marks from module I with choice to answer any one QIII. feasibility studies.Construction expenses .Advantages and disadvantages. QII .Business and legal procedures of project contracts .Budgeting and financial control – Personnel recruitment and training. Module IV Analogy between momentum. Mass Transport: Molar fluxes – Fick’s law of diffusion – diffusion through a stagnant gas film – diffusion into a falling film. 2 from each module. QV .5) (2 X 15) = = = = 15 30 05 50 University examination Pattern QI .thermal conductivity of gases and liquids theory of diffusion in gases and liquids Module II : Shell Momentum Balances: Equation of continuity – momentum equation – energy for three dimensional flow application of differential equation of fluid flow to specific problems. Module III : Shell Energy Balances: Boundary conditions and temperature distribution solids and laminar flow – free and forced convection. QIV-2 questions A and B of 15 marks from module III with choice to answer any one. QIII .91 Internal work assessment Assignments Tests Regularity Total marks (2 X 7. QII .8 Short type questions of 5 marks. Reference: 1.2 questions A and B of 15 marks from module II with choice to answer any one. BT04 805(D): TRANSPORT PHENOMINA 3 hours lecture and 1 hour tutorial per week Module I : Transport Properties: Theory of viscosity of gases and liquids . heat and mass transfer mechanism of interphase transport – two film theory – penemation theory Application of transport phenomina in bioprocess engineering. Bird Stewart and Lighfoot: Transport Phenomena .2 questions A and B of 15 marks from module IV with choice to answer any one.2 questions A and B of l5 marks from module I with choice to answer any one. QV . Elementary study o f various metals and alloys.2 questions A and B of 15 marks from module I with choice to answer any one QIII. eutectic and Peritectic systems. crystal systems.8 Short type questions of 5 marks. recrystallisation. QII . comparison of properties and their relationship with chain structures. Module II Organic polymers and their properties . properties and applications of ceramics. crystal structure.Reinforcements.aging of rubber.single phase metals and alloys.5) (2 X 15) = = = = 15 30 5 50 University examination Pattern QI . 2 from each module. processing and applications. Module III Corrosion – different types.92 Internal work assessment Assignments Tests Regularity Total marks (2 X 7. atomic bonding and atomic arrangement.classification . mechanism and factors influencing corrosion. Oxidation . QIV. oxidation of metals and radiation damage.2 questions A and B of 15 marks from module III with choice to answer any one. plastic deformation. corrosion prevention . . binary equilibria involving solid solution. fillers and additives. Metallic phases and their properties .classification. co-ordination number. Ceramics – Comparison of ceramic and non ceramic phases.inhibitors and their applications. non crystalline structure and crystal defects. structure.2 questions A and B of l5 marks from module II with choice to answer any one. Module IV Composite materials . iron carbon diagram.2 questions A and B of 15 marks from module IV with choice to answer any one. BT04 805(E) : MATERIAL SCIENCE AND TECHNOLOGY 3 hours lecture and 1 hour tutorial per week Module I Atomic structure. BT04 806(P): IMMUNOLOGY & GENETIC ENGINEERING LAB 3 hours lecture and 1 hour tutorial per week 1 2 Blood grouping. Gel electrophoresis of proteins. 2 from each module.2 questions A and B of l5 marks from module II with choice to answer any one. QIV .2 questions A and B of 15 marks from module IV with choice to answer any one. Separation of lymphocytes from blood.Theory of composites. Selecting Engineering Materials for Chemical a nd Process Plants. Preparation of antigens-protocol of immunization in rabbits. QII. Antigen .2 questions A and B of l5 marks from module III with choice to answer any one QV . QIII. Reference: 1. Lee Evans. Elements of Material Science. Immunodiffusion. 2. 3 4 5 6 7 8 9 10 11 12 . Internal work assessment Assignments Tests Regularity Total marks (2 X 7.8 Short type questions of 5 marks.antibody reactions . methods. Isolation of Immunoglobulins and characterization. purification and production of polyclonal antibodies.5) (2 X 15) = = = = 15 30 5 50 University examination Pattern QI . J. Van Vlack.Ab conjugation Biotin Ab conjugation and Ab-enzyme conjugation. mmnunoelectrophorosis Affinity chromatography for Ab purification Flurochrome . of bleeding. L.93 Characteristic of composite materials .Haemagglutination.2 questions A and B of 15 marks from module I with choice to answer any one. Immunoprecipitation. Preparation of DNA genomic and plasmid Agarose gel electrophorosis of DNA Preparation of competent cells. 94 13 14 Induction of Lac operon (expression of beta – galactosidase and assay). Internal work Allotment Design & development Testing and Installation Report Total marks : 40 : 40 : 20 : 100 . Cloning of DNA into Plasmid vector. Internal work assessment Regular work and record Test Regularity Total marks = 25 = 20 = 05 = 50 BT04 807(P): PROJECT WORK 7 hours project work per week This project work is the continuation of the seventh semester project – the eighth semester is for the development of the project a detailed report is to be submitted at the end of the semester .the assessment may be made individually and in groups. Internal work Assessment Subject Project Seminar Total : : : : 40 marks 40 marks 20 marks 100 marks *********************************** .the University will appoint examiners for conducting the viva voce examination – the examiners will ask questions from subjects studied for the B. Tech course. project and seminar reports of the student .95 BT04 808(P): VIVA VOCE There is only University examination for this .the relative weightage should be as follows. Documents Similar To Bt - 2004 SyllabusSkip carouselcarousel previouscarousel nextProjection of PointsElectronics Final CoachingEffect of Transient Voltages on PowerWikipedia Orgeoee-12.pdfP10 MetalDet G4 FinalReportProjection of Lines(New)Lecture_5 (1)FAA-8083-30_Ch02LT Spice - Transformers - ( by Mike Engelhardt )Graphic Science - Engineering Drawing, Descriptive Geometry, Graphical SolutionsRevised Syllabus for B.E. 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Borang Permohonan Skim Zamalah (UTeM.29.1.25)Tutorial 1Tutorial 2Lego Mindstorm KompendieLego Mindstorms Segway Project Report2Footer MenuBack To TopAboutAbout ScribdPressOur blogJoin our team!Contact UsJoin todayInvite FriendsGiftsLegalTermsPrivacyCopyrightSupportHelp / FAQAccessibilityPurchase helpAdChoicesPublishersSocial MediaCopyright © 2018 Scribd Inc. .Browse Books.Site Directory.Site Language: English中文EspañolالعربيةPortuguês日本語DeutschFrançaisTurkceРусский языкTiếng việtJęzyk polskiBahasa indonesiaSign up to vote on this titleUsefulNot usefulMaster Your Semester with Scribd & The New York TimesSpecial offer for students: Only $4.99/month.Master Your Semester with a Special Offer from Scribd & The New York TimesRead Free for 30 DaysCancel anytime.Read Free for 30 DaysYou're Reading a Free PreviewDownloadClose DialogAre you sure?This action might not be possible to undo. Are you sure you want to continue?CANCELOK