All McQs.pdf

May 26, 2018 | Author: AhmedLashin | Category: Drugs, Medicine, Medical Treatments, Pharmacology, Clinical Medicine


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1.Drug is stored in the body a.fat b.protein c.connective tissue d.muscle e. a+b 2. if a drug has the same active ingredient like other drug but not contain the same inactive ingredient this mean: a- Bioequivalent b-pharmaceutical equivalent c- Pharmaceutical alternative d- A,B 3. Enkephalins are peptides that: a. have narcotic antagonist activity. b. exert actions resembling those of opiates. c. are found only in the central nervous system. d. cause blood vessel wall relaxation. e. transmit pain impulses 4.To know the severity of immunodeficiency in HIV, a. ESR b. Leukocyte count c. WBC count d. CD4 count 5. The ethical principle of veracity requires that: a. we respect the rights of others to make choices. b. we act with honesty, without deception. c. we avoid, remove or prevent harm. d. we do good to patients. e. we act with fairness. 6. The style of management in which the owner of a pharmacy emphasizes the development of detailed policies and written procedures for employees to observe at all times is referred to as: a. autocratic. b. bureaucratic. c. participative. d. benevolent. e. consultative. 7- A patient purchasing sublingual nitroglycerin tablets should be told to store the medication: a. in the refrigerator b. in a plastic vial with a childproof cap. c. with the original cotton. d. in an amber glass bottle with a metal cap. e. in a warm, dry place 8- Following the ethical principle of no maleficence requires that pharmacists: a. respect the rights of patients to make choices. b. do good to patients, placing the benefit of the patient above all else. c. avoid, remove or prevent harm from people. d. act with fairness, allowing people access to pharmacy care. e. act with honesty, without deception. 9- prep. containing coal tar 30 part petrolatum 15 part adeq. to 150 part what conc. Of petrolatum in 500ml: 30 parts+ 15 parts are in total 150 parts 15 parts of petroleum are in 150 parts X parts-------------------------500ml, x=15*500/150=50 parts of petroleum 10. Hydroxyurea is: Used to treat sickle cell disease, polycythemia vera, myloproliferative neoplasm (bone marrow cancer) 11. Which one of the following Estrogens Taken Orally: a. Estrogen b. Estrogen Gluconate c. Estrogen Malate d. All of above 12. The responsibility of pharmacist in hospital is to deal with a- administration of drug b- deal with patient c- deal with drug interaction d- notice effect of drug 13.Plasma concentration of drug in body a- rate of absorption b- rate of distribution c- rate of binding d- therapeutic volume 14. The following statements are wrong about domperidone except a- anti-emetic without CNS effect b- anticoagulant c- anti-emetic with sever CNS effect d- non of the above 15. You should keep the prescription of narcotics in the pharmacy for a- two year b- three years c- four years d- five years 16. Pka of normal water at room temperature is a. 7 b. 14 c. 10^7 d. 10^14 e.10^-14 17. drug make urine red other than rifampicin Nitrofurantoin , phenazopyridine (Pyridium), and laxatives containing senna 18. Syncope may occur at first dose of following a.Digoxin b. Salbutamol c. Prazocin d. Reserpine e. Clinodine 19. Which one is more effective against traveler’s diarrhea quinolones have been the drug of choice: a_amoxiciilin b.ciprofloxacin c_sulphamethoxasol d_erythromycin 20. Antihypertensive produce tachycardia: a)Hydralazine b)Reserpine c)Methyldopa d)Atenolol e)Clonidine 21. the action of digoxin can reduced with a_ antacid b_verapamil c.hypokalemia d_hypothirodism e_hyperthyrodism 22. the main cause of digitalis toxicity is a_diabetes milli b_ hypertension c_hepatitis d.renal failure 23. digitalis arrhythmia can be treated with a_lidocaine b_quinidine c_procainamide d_propranolol 24. which one used in ventricular arrhythmia with heart block a.Phynetoin b. procainamide 25. which one is antiarrythmic class 1A a_phynetoin b_disopyramide c_propranolol d_verapamil e_propafenon 26- anti cancer derived from venca is_ a_cyclophosamide b_flourouracil c_doxurubcin d_ cicplastin e. none of above 27. which one used to trigeminal neuralgia: tegretol (Carbamazepine) 28. the solution contain 9ppm of NaCl the the concentration of the compound in the solution a_0.9 b_.09 c_.009 d_.0009 e_.00009 29- Process require CYP450: a)OXIDATION b)HYDROLYSIS c)GLUCORONIDATION d)DEAMINATION e)SULFERATION 30- Adsorption , which is not true: a) Chemical property b) Physical property c) Reversible d) Irreversible e) A + d 31- about steady state concentration during IV administration a_directly ptoportional to volume of distribution b_inversly proportional to volume of distribution c_directly ptoportional to infusion rate d_ inversly proportional to total body clearance e_ c&d 32- _ which of the following decrease gastric emptying rate a_ metoclopramide b_ atropin c_ hypothyrodism d_a&b e_b&c 33- one of following is not alpha 2 agonist: a) Clonidine alpha b) Alpha methyl noradrenaline (Nonselective, acts on Beta1, alpha1+2) c) Guanfacine d) Guanabenz e) Guanethidine 34- about side effect of quinidine: Cinchonism 35. about digitoxin , which is false: a) Oral bioavailability 100% b) Protein binding 95% c) Half life is 7 days d) Mainly hepatic metabolism by microsomal 36- Volatile substance given by inhalation: Halothane 37- to compare between 2 drugs use: a) Physical appearance b) Weightif comparing bioequivalency)) c) Pharmacokinetic parameters if effect d) Pharmacodynamics parameter e) Taste 38- about sid effect of oral contraceptive except: a) Depressoin b) Hypertension c)constipation 39- drug used in ventricular arrhythmia: a) Phenytoin b) Quinidine c) Digoxin d) Procainamide e) Verapamil 40- in tolerance patient need more dose to obtain the same effect 41- causes of hypo thyrodism : : iodine deficiency , low hypothulmus&pituitary hormons 41- phenytoin uses other than anti convelcent agent are: ttt irregular heart beat & ttt painful nerve coduction (neuralgia 42- arrhythmia due to : dysfunction in generate heart pulse or coduction of it 43- Hydralazine, vessel relaxation. It dilates arterioles more than veins. 44- Guanthedin SE are all a-prevent ejaculation b. orthostatic hypotension c- diarrhea 45- not from WBC a- reticleucyte 46- about minoxidil a - it decrease myocardium contractility b - dilate arteries only c- cause bradycardia 47- mizolastine a- antibiotic b- anticoagulant c - anti platelet d- non-sedating antihistaminic 48- all these drugs are anti-metabolite except Cisplatin 49- about digioxin what is not true taken only orally 50- Captopril and Enalapril do all the following except: a. increase renin concentration in blood b. Inhibit an enzyme c. competitively blocks angiotensin 2 at its receptors d. Raises blood potassium conc.(Hyperkalemia) 51- Various opiates may be used as all of the following except: a- Analgesics b- Anti inflammatory c- Antidiarrheal d- Aids to anesthesia e- Antitussive 52- Which of the following action is not seen with sympathomimetic? a- Pupil constriction b- Increased heart rate c- Bronchiole dilation d- Systemic blood vessel constriction 53- Which of the following betaadrenergic agents is not short acting? a- Pirbuterol b- Salmetrol c- Terbutaline d- Albuterol e- None of the above 54- Which of the following drugs is not a Tricyclic Antidepressant? a- Trimipramine b- Maprotiline (tetracyclic) c- Nortyptylline d- None of above 55. Most common disintegrator in compressed tablets is a. Dextrose b. Lactose c. Starch d. potassium bitartarate e. powdered sucrose 56. Which of the following is found in Vitamin B12 a. Magnesium b. Iron c. Cobalt d. Sodium 57. Gums are used in Tableting Primarily as a. Disintegrators b. Glidants c. Lubricants d. Binding Agents e. both b & c 58. Cyclosporine is used for a. allergies b. angina c. prevention of transplant rejection d. steroid deficiency e. treating lead poisoning 59- Ultra-short acting barbiturates are used primarily as a- Sedatives b- Hypnotics c- Antispasmodic agents d- Anti-parkinsonian agent e- Pre-anesthetic agents 60- for a 4 year old child, the maximum daily dose of Paracetamol is a- 240mg b- 480 mg c- 1 g (240m g QID) d- 2 g 60- To supply the myocardium with O2 shortly after myocardial infarction we give a-anticoagulant b-fibrinolytic c-aspirin d-ACEI 61- - Which one of the following cannot be dispensed without prescription: a- Ibuprofen b- Doxycycline c- Aspirin d- Bisacodyl 62- - The aim in the management of uncomplicated hypertension a- <90/65 b- <130/85 c- <150/95 d- <180/110 63- A hospital on formulating drugs, Efficacy, Work overload, and Costs are taken in concern. A, B, C, D, and E are antifungal drugs available in the market. All have the same efficacy. The hospital was using drug E for a period of time. According to the following data which drug is best to be used by the hospital? DRUG COST FREQUENCY DURATION A 3.25 BID 14 DAYS B 2.25 ONCE DAILY 14 DAYS C 5.5 BID 7 DAYS D 2.25 BID 7 DAYS E 3.00 QID 7 DAYS A.91 dollar. 31.5 dollar, C.77 dollar, D.31.5, E,84 dollar D is most economical and because pharmacy has less staff so it can be managed easily 64- Solid dosage forms are better than Solution dosage form because: a- Accurate dose b- Easy to handle c- More stable d- Faster action e- a & b and c 65- Tolerance is a problem when using Nitroglycerin, which of the following is true: a- Tolerance doesn't occur in young patient b- Over 50 years patient doesn't develop tolerance c- Dosing schedule may affect tolerance d- Isosorbide dinitrate doesn't develop tolerance 66- arranging the electro magnetic waves alpha,,, beta,,,gamma in an increase ranking in air will be a.alpha,beta,gamma b-beta,gamma, alpha c-gamma,,alpha,,beta d-alpha,,beta negative,,,gamma,,,beta positive 67- gray man syndrome due to amiodarone 68- - indapemide used in Pulmonary eodema Essential hypertension Angina pectoris 69- one of the followimg not related to heparin a-prevent blood clotting b.decrease antithrombine time c-prevent formation of factor VII d-used in pulmonary embolii Warfarin affects the vitamin K-dependent clotting factors (II, VII, IX,X) , whereas heparin and related compounds increase the action of antithrombin on thrombin and factor Xa 70 - Which not effect of caffiene: a)preiphral vasoconistriction b)cardiac stimulation c)dieresis d)skeletal muscle relaxant e)stimulation of C.N.S 71- -Hypertonic solutions can be adjusted by: a-Add Nacl salt to solution b-add any other salt c-Make dilution by add more solvent d-This solution can not be adjusted e.None of above 72- - entero Hepatic recycling depend on all of the following except: a-Dosage form of the drug b.Extent of drug passed in feaces c. extent of drug absorption from stomach d-gall bladder state 73- -if we have a solvent costs 150 riyal/kg and its specific gravity =1.07 ,so the cost for 100 ml of the solvent is? 16.05 150 is price of 1000ml=1kg, x-----------100ml, x=100*150/1000=15, 15*1.07=16.05 Riyal 74- which of the foll. drugs show most multidrug resistance a)antibiotics b)anticancer c)a&b 75- . The following liquids are least likely to be miscible: A. polar + polar B. non-polar + polar C. non-polar + non-polar D. all of the above will be miscible E. Band C 76- At 25° C, benzoic acid is much more soluble in benzene (C6H6) than it is in water. In this situation benzoic acid could be considered to be: A. Hydrophilic B. Colloidal C. Non-polar D. Polar E. Both A and D 77- The following properties are similar for both solutions and suspensions: A. The components of both solutions and suspensions can be separated from each other by physical processes. . B.Solutions and suspensions are composed of two or more components . C. Solute in the solutions and suspensions settle out over a period of time. D. Both A and B E. Both Band C 78- Concerning COX-2 inhibitor, which is not true? A. they have lower risk gastric adverse reactions than non-selective agents B good evidence about their effectiveness in osteoarthritis C. cardiac toxicity is a recent concern of this class of drugs A marked decrease in the level of glucose following the initial dose of prazocin. Ischemic damage due to vasoconstriction and tissue hypoxia. D. Headache and constipation. Causes the release of stored acetylcholine.the pharmacological property of amphetamine is: A. C. Tachycardia C. alendronate should be taken in the morning 60 min before breakfast B. A. Metabolized by phosphodiesterase II. E. combination with non-selective agents provide additional benefit 79. they are.Side effects of albuterol include which of the following? A. usually administered once or twice daily E. Bradycardia B. B. which of the following is not correct: A. E. 83.all the following diazoxide side effects except . Convulsion D. 82. B. 81. Skin rashes. A marked increase in the level of glucose following the initial dose of prazocin. Causes release of stored norepinephrine. C. Hypoglycemia due to increase insulin release. outcome should be assessed with periodic bone density studies E. raloxifene is selective estrogen modulator that is contraindicated in DVTpatients 80. Hypotension E.Which of the following statements describing first dose phenomenon that associated with prazosin is true? . D. Alopecia. Causes release of estrogen. 84. calcium and vitamin 0 are essential C. B.In the treatment of the osteoporosis. Does not cross the blood brain barrier. Which of the following side effects is associated with the use of norepinephrine: A. hormone replacement therapy (HRT) should be considered in all postmenopausal patients with osteoporosis D. Nausea and vomiting. D. C. A marked increase in the level of cholesterol foilowing the initial dose of prazocin.D.. A marked postural hypotension 30 to 90 minutes following the initial dose of prazocin. a-increase the distance from radiation source .hypotension 85.isopreterinol 86.thiopental is? a ) short acting barbiturates b ) long acting barbiturates c ) spinal anaesthesia d ) antihistaminic e ) antibiotic 88.wich statment about radaition parameters or units is false a.ranitidine d.phosphodiasterase inhibitor e.none of the above* 87.Gray (Absorbed dose) is a physical quantity which represents the energy imparted by radiation onto an absorbing material.amphetamine e.a-tachcardia b-diuresis c-hyperglyemia dhyperuricemia e.Roentgen (Exposure) is a quantity that expresses the ability of radiation to ionize air and thereby create electric charges which can be collected and measuredd.increase ca intercellular d.3 ) amount of drug is 5 mg in 1 ml what the amount of drug in 1 tsp in microgram a ) 5 b ) 25 c ) 500 d ) 2500 e ) 25000 (25mg in 5ml(1TSF) 90.Becquerel is the transformation (disintegration) rate of a radioactive substance b.bretylium b-phenytoin c. d. c.Milironin has following except: a-+ve inotropic b-vasodilator c.which one causes hypotension due to blockage of efferent limb baroreceptor reflex a.Digoxin action except:a-+ve inotropic b-shorten refractory period in atrial and ventricular myocardial c-increase conduction velocity in AV node d-contraction of myocardial muscle 91.potantiate the effect of CAMP 92.which of the following is not macrolide antibiotic? a ) erythromycin b ) spiramycin c ) chloramphenicol d ) clarithromycin e ) azithromycin 89 . -suspension eye drop differ than ophthalmic solution in: a-less commonly used b.how many gm of water add to 5% KCL soln to make 100 gm of solution(w\w a-95 94.insoluble 95.a&c 103.relax of biliay muscle c.Which one of the following cause hypertensive crisis if withdrawn suddenly a.cushing .put shelves d-decrease the activity of radiation person 93.decrease contact time of drug with eye c.Pindolol e-propanlol 99.Amber plastic 100 . vasodilation b.protect from light" in usp means: a.used for insoluble drugs d.decrease blood pressure 97.slow heart rate d.which of these have intrinsic sympathomemtices effect: a-labetlol b-timlol c--nidlol d.Very small molecule(1 part ) soluble in more than 10.Light resistant container d.-most potent anti-inflammatory corticosteroid systemically is: a-cortisone b-hydrocortisone c-triamcinolone d-prednisone e-dexamethasone 102.like syndrome is due to .taken sublingually e.which one is not effect of Nitroglycerin a.plastic container c.Amber glass e.miscible e.Clonidine b.hydrochlorothiazide c-blocker prazocin 96.DAILY intake of vitamin A for adult female is: a-500 mcg b700 mcg c-1500 mcg 101.air tight container b.000 part of water a.fairly soluble bslightly soluble(Very slightly soluble) C-immiscible d.solubility c-crystalitis d-drug form 98.drugs have different crystal structures so different in a-polymorphism b.b-out from the place of radiation c. ray d)a+c 107. -which is (are) electromagnetic waves……????? a)X-ray b) Beta. B .Vecuronium.Michaelis–Menten law..both a and c 108. E .not substrate for chatechole o methyltransferase ( COMT) d-all of the above e.enzyme kinetics law : A .used in nasal decongestant b-in high doses stimulate beta adrenergic receptor c.direct acting adrenergic agonist. C -franks law.Henderson hasselbach law.a) adrenal hyperplasia b) adrenal hyporplasia c) Hypothyroidism d) hyperthyroidism 104. . Calcium-channel blockers mode of action a) increase the inward calcium to cells b) decrease the inward calcium to cells 106. D . B -direct acting adrenergic antagonist. C -pancuronium. D -gallamine.-amphetamine pharmacological action: A .b&c 111.One of the statement considering Tetracaine One of neuro muscular blocker In the ttt of T. B -henry s law. E – atracurim (Cis-Atracurium) 110.Neuromuscular blocker is used of choice in renal and hepatic failure: A -tubocurarine.ray c) Gama.BOpioid analgesicVit d metaboliteThe most one of choice in spinal anaesthesia 109.-Phenylepherine a.Morphine causes respiratory depression by a) depression of respiratory center in brain b) activation of respiratory center in brain c) depression of CTZ receptors center in brain d) activation of CTZ receptors center in brain 105. 559*331. 500*0.23=185.84g.0156 m e. E –muscarinic acting agonist 112.559 M is (Mwt=331.882 b-0.157gram Wt.95g\cm3.0.most described dosage solid form: powder . how many doses? doses 90 / 0. density of the solvent =0. soft capsule .indirect acting adrenergic agonist.157g/ml*1000ml=1157g Wt.475Kg Cm3=ml Stept3=determine molality Step1/step2=0.9718Kg Step 3=determine molality Molality= no.8687 g cacl2 in 500 ml solvent. of solution=d*v=1.0165 m d. of moles Molecular weight of Cacl2=111 0. of moles of solute/Kg of Solvent Stept1= determine no.0.007826/0.559/0.475=0.8687g/111g=0. 475g.0230 m Molarity= no. 971. tablet .559 moles Step2= determine mass of solvent in Kg Wt.drug container contain 90 mg each tablet contain 0.575 molal 114.84/1000=0.559 d-0. 0.C .indirect acting adrenergic agonist.0. both types of capsule 116.157=971.Dobutamine is used as : .23 g/mol& density of solution =1.of moles of solute/kg of solvent.007826 mole Step2= determine mass of solvent in Kg M=d*v.575 molarity= no..0156 Molal c.75 = 120 115.0165 Molal b.Find the molality a. D . of moles= 0.882 c-0.of solvent= 1157-185. of moles No.157g/ml) is: a-1. hard capsule . 475g/1000g=0.95. of solute=0.0.0.The Molal concentration of 0.has 5-HT antagonist and H1 antihistamine effects Cyproheptidine 117.0165 molal 113. of moles of solute/ Liter of solution Step1= determine no.0.75mg.9718= 0. Converting big fragments into small fragments is Reduction 125.all these drugs used in amoebic dysentery exept a.sulphonyle urea indapamide ( natrilix) --.Atropine sulphate b.Enzymatic reactions c.Butrepium bromide 120.sol contain D5W another one contain D50W we want to prepare sol contain D15W its volume is 450ml how much ml we need of each sol 5% ---------------------------------.Body fluid interaction b.All of the above 118..Stomach PH. ceftazidime is 3rd generation cephalosporin Amantadine is.(350ml)10 122.i.p.. gentamycin d. 124. 119..q.Iprotropium bromide e.tetracyclin 121. Bretylium class3 anti antiarrythmic is an adrenergic neuronal blocking agent also its k+ channel blocker 129. ethosuximide 132.qqh means every 4 hours 128.Ready programmed & no influece of the body fluid d. parameter describing dissociation in solution : .s=q. Mebeverine d.Freeze drying is done by Sublimation.In cardiac surgery c. ANGIOTEC is the trade name of Enalapril the 133. diloxanid c.Terbutaline is used as Antiasthmatic 123..Parasympathomimetic b.Hypotensive agent d.d. Indamide use ----.r-----for the rectum 127. drug used in abscence seizure(petit mal seizures).d= four times per day 126.Hydroatropine c.metronidazole b.All of these are antichlonergic except: a.35= (100ml) 15% 50% -------------------------------.Controled released drug delivery depends on: a.a.thiazide diaretic 131. increases dopamine release and blocks dopamine reuptake Diphtheria is an upper respiratory tract illness caused by Corynebacterium diphtheria 130. its also called grand-mal epilepsy and Pit maybe start with aura or not and it affect both children and adults. phentolamine (Regitine) is a reversible nonselective alpha-adrenergic antagonist Abbreviations Considerable variation occurs in the use of capitalization. Amyl nitrite 141. The following list shows the abbreviations that are not often encountered by pharmacists: . shortening in breath 137.……… occur in children . Phase 1 of Arrhythmia: initial depolarization is due to a transient and active potassium efflux. mechanism of action of hydrochlorthiazide Inhibits NaCl reabsorption in Distal Convoluted tubule 138. major side effect of nitrates is Throbbing Headache 140. blurred vision d.Sulfinpyrazone is a uricosuric drug 143. MAOI work through : increase avialability of monoamine neurotransmitter 136. 142. volatile liquid drug given as inhaler……. and loss of alertness (consciousness) --. unvoluntry movement The seizures usually involve ( tonic phase )muscle rigidity. c. unconciousness .Pka 134. constipation. followed by violent muscle contractions( clonic phase) . about tonic clonic seziure: . all thefollowing side effect atropine except a.urinary retension b. reserpine mechanism : deplete catecholamines from sympathatic nerve endings 135. italicization and punctuation in abbreviations. Calcium begins to move into the intracellular Phase 2 of Arrhythmia: plateau Phase Calcium influx continues and is balanced to some degree by potassium efflux 139. = as directed a. = give of such doses ante = before DW = distilled water aq. = National formulary q.A. Desk Reference μ = Greek mu p. or o.160 c.A. = every N & V = nausea & vomiting q. = injection o.9.s.6mg.4 hr. = as needed mEq = milliequivalent Pt. 16 b.924 c.n.. how many doses are present in 96mg of drug a.o. = by mouth M = mix Ppt = precipitated M2 or m2 = square meter Pr = for rectum Mcg.0. = at bed time ½ NS = half-strength normal saline IM =intramuscular O = pint Inj. or aa = of each comp. = divide.1500 . = each eye.u. drops Non rep. = left ear elix = elixir asa = aspirin e. = right eye every day IV = intervenous o.p. At pleasure freely div. described as written GI = gastrointestinal Cc or cc. mcg or μg = microgram Prn or p. = ampoule d. aa.dc.6=160 doses 145. or disc.433grains. both eye K =POTASSIUM oz. 360 d. = in water BP = British pharmacopeia fl or fld = fluid BSA = body surface area fl oz = fluid ounce c. 600 e. = night. Convert 2pint 3fliud ounce into ml a.I.S. = before meals dil = dilute ad = to. = water D5W = dextrose% in water a. both ears et = and b.0.W. = each ear. = left eye IVP = intervenous push OTC = over the counter IVPB = intervenous piggyback o.s. = ounce I or L = litre p.t.m. 9240 b. = compound. up to D. = every hour Noct.d. = twice daily ex aq.s.d.h. in the night q. = right ear disp. cubic centimeter gr or gr = grain Gtt or gtt = drop.F.24 d. = morning dl or dL = deciliter amp. = hour N. Convert 60 grams to grains a.d.. to be divided a. =every day N.m.c.433=924grains 146.u. = pint mg = milligram Pulv.d. none of above 96/0.c. = after meals Lb = pound PDR = Physicians. NS = normal saline h. = every 4 hours 144.. 60*15.d.924 e.C. = dispense ad lib. the dose of a drug is 0. compounded a.or c = with ft = make cap or caps = capsule g or GM =gram cp = chest pain gal = gallon D.0924 1gram=15. = do not repeat H = hypodermic NPO = nothing by mouth h or hr. = discontinue a.i.r. = powder ml or Ml = milliliter Pv = vagenal use μl or μL = microlitre q. ACE inhibitors are used in the treatment of: a.105 e. c.effective hypotensive when others are contraindicated (B-blockers & diuretics) c.Aldactone. 7.57ml 147. (captopril is more potent than other ACE inhibitors) b.10. sodium stibogluconate Prepared by Dr.Migraine.176ml.converting Ag 1 to vasodilator Ag11 d.1050 c. which of the following drug is a systemic ameobecide a.converting Ag 1 to vasoconstrictor Ag11 c. d.Mode of action. . c.The diuretic which is used with Captopril is: a.converting Ag 11 to vasoconstrictor Ag1 b. 3. d. emetin d. diloxanide furoate b.5 1pint=473.Atenolol. c.thiazide 4. d.Has a valuable role in heart failure.Ethacrynic acid.Asthama.Hypertension.Same effect if given in the appropriate dose. d. M U Khan 300 Questions 1.Which of the following is not cardio specific ß-blocker? a.inhibits the conversion of Ag1 to Ag11 b.Furosemide. 1fluid ounce=29.Differences between captopril and other ACE inhibitors: a. b.ß-blocker is used for: Essential hypertension.150 d. 6.b.All of above 5.All of the above.ACE mechanism is: a.pyremethamine c.Differ in shape.Differ in potency.converting Ag 11 to vasoconstrictor Ag1 2. b.What are the effects of Captopril? a. Which one is not Ca channel blocker? a. d. c.quinidine (anti arrhythmic supra ventricular) b.Satolol.Anti hypertensive agent.Hyperuricamia.Atenolol.What is the pharmacological & / or therapeutic classification of the following drugs: a.All of the following are ß2 antagonists except: a.ß1 agonist cause: a.Betoxolol non selective ß-blocker.Hypokalamia. d. d. d.Nifedipine. N. 15.Metoprolol. .procainamide is like: a.verapamil.True 16.Timolol non selective ß-blocker.Thiazide diuretics cause all the following except: a.Labetalol non selective ß-blocker.Thiabendazole is one of the Thiazide diuretics: a. 12.Salbutamol.Increase in oxygen consumption.All of the above.Lisinopril. b.b.Anti arrhythmic agent.Deltiazem.One of these is not like the others: a.Increasing ectotopic effect.Acebutolol. b. d.False b.Hyponatrimia.Labetalol: nonselective ß-blocker hypertensive. b. b.Nadolol.Acebutalol selective ß-blocker.Cilazapril 14. 9. d.(also has Alpha activity) d. c.B. c.quinidine sulphate is: a. b.Hypercalcemia. 8.Acebutolol: selective ß-blocker hypertensive.A & C. c.Amlodipine.Labetalol. d. c.Cinnarzine. 10. c.Anti malarial agent. b. 13.: Salbutamol is ß2 agonist 11.Increasing intotopic effect. c. b. c. because: a.parasympathomimmetic.All of the above. d. d.Dobutamine is given I. 25. c.Potent vasoconstrictor.Hypernatremia. b.Hyperglycemia. (diuretic increase excretion of sodium chloride but lessens potassium).It is needed in large doses if taken orally.Atropine sulphate. c.ipratropium.e. 19. 18.Nitroprusside Na is: a.Potassium supplement therapy must not be given with: a.All of the above.Ipratropium bromide. b.Methyl dopa.It is eliminated very quickly.Benzatropine methylate.All these drugs are anti-cholinergic except: a.Potent diuretic.Epinephrine has Alpha and Beta agonist activity so cause: a.Hydrazine is used as antihypertensive through: a.Potent vasodilator. d.It causes nausea & vomiting orally.Decreasing cardiac output. 23.Aspirin. b. c.Hypotensive agent.Hypotension.Triamterene. 21. b. b.Paracetamol.Atropine sulphate.Piroxicam.Increasing in heart rate and increasing in blood pressure.Dobutamin. c.Dobutamine is used as: a.All of these are anticholinergics except: a.Butrepium bromide. d. 20. b. c. d. d.Decrease heart rate. f.V. b.Which of these has no vasodilator effect? a. 17.In cardiac surgery. c.Mebeverine. . 22. c. d.Vasodialaton. e.Diuretic. b. 24.Hydroatropine.Anti arrhythmic agent.It is not stable in gastric acid of stomach. c. d.Theophylline is: a.Stimulation of the CTZ. 35. 30.Increased metabolism & dose must be increased. c. b.Inhibition of the stomach through CNS. b.Caustic substance ingestion. d.Corticosteroid for long period of time.b.Long acting bronchodilator + corticosteroid.Paracetamol poisoning. d.Introduction of emesis is not indicated in the following except: a.Zinnat contains: a.Short acting bronchodilator + steroids.Cefaclor. d. 29. b.viral infection.Seizures. 36.URI.Stimulation of the stomach. c. 28.GIT infection. 31. c.Hydrocortisone.All of these are anions except: a.Theophylline does in children: a.Ipeca is emetic agent which induces emesis through: a. thereforefore dose /kg is increased greadually.Urinary tract infection (UTI). . b.Prazocin.Human albumin.ß2 agonoist. 32. d.Broncodilator.Hydralazine.Decresed metabolism & dose must be increased. c.The modern method to treat asthma is to use: a. b. b. d.( children from 6 months to 16 years of age have high theophylline clearance due to increased hepatic metabolism. 34.Cefuroxime.Decresed metabolism & dose must be decreased. c.CNS.Enalapril.Treatment of anaphylactic reaction is indicated in the following except: a. 33. c.All of the above.Cimetidine.nintrofurantion is indicated for: a.Causes bradicardia. b. b. c. d. c.Epinephrine.A & B.Phosphate.Long acting bronchodilator only. c.Insulin.500 ml normal saline 0. c. b.Erythromycin.Pivampicillin. 42. c.None of the above.b. b.Triazole is: a.Diabetes mellitus type I. d.Sulphonylurea.5 gm.Nyatatin.Blood pressure.False. all these parameters should be monitored except: a. 46.Diabetes insipidus (used in bleeding oesophageal varices) b.The trade name of amphotrecin B. c.Treatment of gastric & duodenal ulcers.Ampicillin.Diabetes mellitus type II.Give two indications for allopurinol: a.Prophylaxis from gout. 41. d. 38. b.Vasopressin is used for the treatment of: a. d.Urine flow rate.Glibenclamide.(4500mg) 47. 37. b.Treatment of high uric acid & calcium oxalate renal stones. 44.Acetate. .Which minoxidil.Chloride. d. 40.Sodium.Body weight. 39.Insulin. d.famotidine is H2 antagonist used for: a. d.Antifungal.A & B.Pulse rate.Type 1 diabetes advises to use: a.The trade name of clotrimazole.True b. b.misoprostol [cytotec = prostaglandin] inhibits gastric acid by blocking hydrogen-potassium adenosine triphosphate enzyme system [ATP] of gastric cell: a.Hypertension. 43. 45. b.Enalapril is the prodrug of: Enalaprilate.Diet control.9% contains 4.Type 2 diabetes advises to use: a. Nacl. c.Which one is prodrug: a. c.All of the above. c. Calcium supplement. b. d.INH means: a. c. except: a. b.Cycloserin.One week.One month.A & B.acetohexamide (one of silphonyl urea) is hypoglycemic.Two week.B.Used for the upper respiratory tract infection. b.Vitamin A. c. d.Which one of the following is not contraindicated in pregnancy? a.Captopril. d. d. d.Rifampicin.For influenza A. c. 57.The duration of treatment of T.Six month & over.Paracetamol.Which one of the following is contraindicated in pregnancy? a.Enalapril.Cytotec is [misoprostol]: a.calcipotriol ( daivonex) is indicated for: a.Calcium. 53.One of the following should be avoided in pregnancy: a. 58.Antiviral. by CTC is: a.Amantadine is used for all of the following except: a. b. d.Used for gastric & duodenal ulcer.Hypertension.B. .All these medications are used in the treatment of T.Ethambutol. b.Isonicotinic acid hydrazide.Simvastatin is used for hypolipidemic action.Methyldopa. c. 52.Psoriasis. 56. 49.Misoprostol. b. 50.A & B. 55.Lisinopril. 54. c.isoniazide. c.48.Cyclosporine.Ciprofloxacin. b. c.Acne.Sucralfate.INH.Chlorpheniramine.Contraindicated in pregnancy. b. 51. d. b. c. What is the most drug can cause damage if it is given OTC? a.Unionized lipophilic.Biscodil b. so: a. 63.Normal saline. c.Chloramphenicol affects liver inhibitory enzyme.amantadine. b.Epinephrine [same adrenaline = a hormone produced by the adrenal medulla on mammals].Increase metabolism & increases response. 66.All these drugs are antiviral except: a. spasmonal) 60. d.Ionized lipophilic. b. b. c. c. d.Rifampicin.Which one is an OTC drug? a.Hydrocortisone. 64.Drugs to pass B.Zidovudine. d.Propranolol.Simple analgesic.At the cardiac arrest (shock). b.B.Warfarin.Decrease metabolism & decreases response. b.Anti-parkinsonism. c. 67. d.Aspirin. c.Influenza.Propranolol. b.Lidocine. d. 59.Aluerin.All are OTC drugs except: a. (anti spasmodic.Hepatitis B. c.c.Riketssia. d. .For influenza B. should be: a. c. 62. b. c.Ciprofloxacin. 61. the drug of choice is: a.Cardiac arrest could be managed by the following except: a.Decrease metabolism & increases response.Saline solution.All are viral infection except: a.Captopril. d.Increase metabolism & decreases response.Herpes zoster.Ephedrine.Ionized hydrophilic. d. 65.Chlorothiazide.B. b.Unionized hydrophilic.Acyclovir.Warfarin. Metformin. c.All are non OTC drugs except: a.The concentration of the drug on expiration date is: a.Carbamazepine. .Sympathomimmetics.Tegretol. c.oxytocin is one of the posterior pituitary hormones.Binding to plasma protein: a. b. c. d.Uterine stimulation.New & best therapy for peptic ulcer is: a. e. 70.Labor induction.Not less than 100%. 76.Antacids. d.Morphine & morpin are similar in: a.Tween.Phenylephrine is used for: a. 77.From 90-110%. b.Bisacodyl. b.For runny nose.Increases half life. d. d.Bisacodyl. 72. b.Analgesic. 75. 69.c.All of the above.Mammalian glands stimulation.All of the above.Tegretol.Decreases half life. b.Use more than H2 antagonist.Surfactant not used orally: a.Addiction.Decongestant. 71. b.Aspirin.Na lauryl sulphate. b. c. c.All of these can be dispensed without prescription except: a.Vasoconstrictor and pressor (raise blood pressure).Progesterone release. d.Miosis. b. 73.Four medicines including antibiotic. c. c.Oxytocin produces all the following except: a.Not less than 90%.Span 74.None of the above. 68.Maalox.Phenytoin. d. d. b. Antihistaminic. 80.5 gm in 8 hours. c.Acts peripherally.7.Diclofenac potassium. 86.7.4 gm in 24 hours.Clofazimine. [The drug of choice in leprosy]. b.Cyproteron (Androcur) is used for: Antiandrogen : decrease sexual ability.Immunocompetent means? Control resistant to infections.Paracetamol.Aspirin.All of the above. c.Dapsone. c. c. d.A & B. d.Acts centrally by blocking chemoreceptor trigger zone. 85. 89.Which one is sporanox? a.Has an anti-emetic effect. b.Cefixime.Meniere.Rifampicin.Dicolfenac Diethlamine.N. b. d. c. b.Analgesic.Betahistine dihydrochloride: a.7. d.H. 83.Miconazole. d. 79.5 gm in 4 hours. c.I. (antifungal).All these can be used in leprosy except: a. 84.in case of osteoarthritis & peptic ulcer of elderly patients use: a. b.Clotrimazole.Diclofenac sodium.Itraconazole.c.Immunocompromised means? Low resistant to infections. b. 82.Maximum use of paracetemol is: a. c.Voltaren Emulgel is: a.Econazole.Strong NSAIDs.Antacid + H2 antagonist.Pneumocystis Carini Pneumonia [PCP] is: . 87. b.Suprax is: a. 78. 88. 81. b.s disease.5 gm in 48 hours.Itraconazole.Metoclopramide is a dopamine antagonist: a. Phynylepherine.(Anti-platelet) 98.A & B. c. b.Carbocisteine. c. d. 96.Guaifenesin. c.All these drugs are fibrinoltic except.Indication(s) of Allopurinol is (are): a. c.Antiplatelet.Aspirin.Virus.Anticholinergic. d.Parasite. d.Prophylaxis of gout. 94.Bromhexine.Urokinase.Which one of the following is not mucolytic? a.Bacteria.Finasteride. 97. 93. b.Which one is Antiplatelet? a.Ceprodoxin.Which one the following is not antibiotic? a.Cefprozil. c. b.(Anti-tussive) 95.Aldesleukin.Anti-coagulant. d.Antibiotic.Otrivin is: a. c.Dipyridamole.Flumazenil. c. 90.Erythromycin. 91. d.Atovaquone. b.Ambroxol.Which one of the following is used in Benign prostatic hyperplasia [BPHP]? a. (proscar). b.Ticlopidine is used as: a. 92. b.Cefprozil. d.Mevacurim. b.Streptokinase.All these are anti-platelets except: a. c.Dextromethorphan. . d.Treatment of uric acid and co-oxalate renal stones.Anistreplase.Desflurane.Ticlopidine hydrochloride. b. a.a.Mycobacterium.Finasteride.Xylometazoline b. e. e.Decreasing the activity of liver enzymes.Vitamin K. b.Anti-coagulant effect of warfarin is decreased by: a. a. b.Heparin.Streptokinase.Drug which decreases [antidote] the action of warfarin is: a. .Dysmenorrhea.Warfarin.None of the above. (deep vein thrombosis) 103. c.Increasing the activity of liver enzymes.Presentin. 105.Dipyridamol. So increases the activity of warfarin. d.Carbimazole.Enoxprine is taken subcutaneous 104. c.Aspirin. So decreases the activity of warfarin.Ticlopidine. b.Verapamil 101. c. d.Oral contraceptive.Nicoumolone.Aspirin is recommended with one of the following.Drug which increases the action of warfarin is: a. when taken with warfarin anticoagulant leads to: a. 99.Anti-coagulant.Increasing the activity of liver enzymes. 102. c. d.Enoxaprine. c.Influenza symptoms. b.Dipyridamole (antiplatelet).All these are anti-coagulant except: a.Carbimazole. c. So decreases the activity of warfarin.Phenobarbitone. b.Decreasing the activity of liver enzymes. d.b.( all above decrease) 106. b.Phenobarbitone induces liver microsomal enzymes.Oral contraceptive.Ancord.Which one is not oral anti-coagulant? a. 100. So increases the activity of warfarin. d.Chicken pox.Rifampicin. d. c.Phenidione.Warfarin. b. d. Vitamin C.Saline.Vitamin C. Opioid -Noloxone. d.Ketoconazole. d. 109.Cimetidine.Vitamin K. 114. Digoxine -Protamine sulphate.Quinolones.Rifampicin.Dipyridamole.Rifampicin.To prevent more toxicity of digoxin we use antidote which is: a. 110. c.Metronidazole.Ketoconazole. Heparin -Protamine Zinc. b.Which one reduces the metabolism of other drugs in the liver? a.Cimetidine.Give the antidote of each of the following drugs. Warfarin -Vitamin K.Digbind.Vitamin C. Paracetamol -Acytylcystiene. 107. d.Which one induces the metabolism of other drugs in the liver? a. b.c. 111.Chloramphenicol.Rifampicin. c.Charcoal. (organic compound) Insulin & oral hypoglycemic -Dextrose.Rifampicin. 108.The antidote of heparin available in fish is: Protamin sulphate.Give an example of a drug inducing hepatotoxicity: a. c. Cyanide -Na thiosulphate.Phenobarbitone. b. d. c. 113. d. Heavy metals -Dimercaprol. 112. .Digotoxin.Which one of the following is an enzyme inducer? a.Cimetdine.( Digoxin Immune Fab Antibody) b.Paracetamol. d. c. Copper & Lead -Pencillamine.Hepatotoxicity is induced due to these drugs except: a. Morphine -Naloxone.Metrinidazole. Iron -Desferroxamine (chelating agent). b. b. c- Rifampicin. d- Quinolones. 115- The cause of death in morphine toxicity is: a- Respiratory failure. b- Heart block. c- A-V block. 116- To prevent more absorption of the toxic drug we use: a- Charcoal. b- Water. c- Salt solution. d- Saline. 117- The common side effect of sulphonylurea is: a- Hypoglycemia. b- GIT upset. c- Thyrotoxicosis. d- All of the above. 118- The side effects of insulin are: a- Local reaction.(urticaria) b- Hypoglycemia. c- Fat dystrophy at the side of injection. d- All of the above. 119- One of the following is the main side effect of insulin: a- Hypoglycemia. b- Fluid retention. c- Hyperglycemia. d- All of the above. 120- Pseudomembranous colitis is a side effect of: a- Clindamycin. b- Vancomycin. c- Reserpine. d- INH. 121- All these are side effects of chloramphenicol except: a- Irreversible a plastic anemia. b- Optic neuritis. c- Peripheral neuritis. d- Iron deficiency anemia. 122- All of these are corticosteroids except: a- Methyl prednisolone. b- Prednisolone. c- Triamcinolone. d- Beclomethasone. e- Dexamethasone. f- Ondansteron [5HT3 receptor antagonist, anti emetic]. 123- All of these are anti-neoplastics except: a- Aldesleukin. b- Teniposide. c- Pentostatin. d- Amlodipine. 124- All of these are antimetabolites (cytotoxic) except: a- Methotrexate. b- Cytarabin. c- Azathioprine. d- Mercaptopurine. e- Fluorouracil. f- Cyclophosphamide.( Alkylating Agent) 125- Levodopa is used with Carbidopa for the treatment of Parkinsonism. 126- All of these are true for Levodopa except: a- Precursor of dopamine. b- Stimulates dopamine. c- Effective in Parkinsonism. d- Does not pass B.B.B. 127- Specific Serotonin reuptake inhibitors are used as: a- Antihistaminic. b- Antidepressant. c- Antihypertensive. d- Anti-emetic. 128- Fluoxatine (Prozac) is: a- SSRI antidepressant. b- Selective Serotonin Reuptake Inhibitor. c- A & B. 129- Ondansetron HCI is used for: a- Emecis. b- Anagina pectoris. c- Prophelaxis of migraine. d- Hypertension. 130- Which one is not 5 HT3 antagonists? a- Tropisetron. b- Ondansetron. c- Granisetron. d- Domperidone, (peripheral dopamine receptor antagonist) 131- The drug of choice for febrile convulsion in children is: Diazepam 250 microgram / Kg. 132- Which one is correct? a- Diazepam is not used for long time. b- Diazepam is taken I.M. only. c- Diazepam is derived from morphine. d- Diazepam can cause muscle spasm. 133- Drug of choice in status Epilepticus is: Diazepam./ Lorazepam 134- The following are the indications of Diazepam, except: a- Antipsychotic. b- Epilepsy. c- Hypnotic. d- Headache. 135- All the following used in treatment of anxiety except: a- Propranolol. b- Diazepam. c- Mebrobamate. d- Homatropine. 136- All of these are anti-parkinsonism except: a- Amantadine. b- Bromocriptine. c- Selegitine HCL. d- Lysuride. e- Pergolide. f- Levodopa. g- Primidone.( anti-epileptic) 137- All these drugs can be used for Parkinsonism except: a- Selgitine HCL. b- Carbidopa. c- Pergolide. d- Nedocramil sodium. 138- One of the following is not used for epilepsy: a- Clorizepam. b- Phenytoin. c- Primidone. d- Imipramine. 139- All the following used in epilepsy except: a- Sodium valproate. b- Carbamazepine. c- Phenytoin. d- Nedocromil sodium (tilade inhaler). 140- One of the following not used in epilepsy: a- Clonazepam. b- Phenytoin. c- Primidone. d- Imipramine (tricyclic antidepressant). 141- All of the following are controlled drugs except: a- Rivotril. b- Stesolid. c- Carbamazepine. d- Barbiturates. e- Diazepam. f- Primidon. g- Epanutin. h- Imipenem. i- G & H. 142- Controlled drugs present in pharmacy are: In tightly closed shelves. 143- Give the name of: Vitamin A- Retinol Acronym: RTRNPPFC Vitamin B1 -Thiamine HCI. Vitamin B2 -Riboflavin. Vitamin B3 -Niacin Vitamin B5 -Pantothenic acid. Vitamin B6 -Pyridoxine HCI. Vitamin B9 -Folic acid. Vitamin B12 -Cyanocobalamine. 144- Zidovudine is used for: a- HIV. b- AIDS. c- P.U. d- A & B. 145- There is one drug used for HIV. a- Zalcitabin. b- Kinasterdin. c- Cefaproxil. d- Enoxacin. 146- Omprazole: a- Acts as proton pump inhibitor. b- Blocks the hydrogen-potassium ATP enzyme system. c- A & B. 147- M.M.R. vaccine is: a- Measles-Mumps-Rubella V. b- Measles-Mumps-Rabies V. c- Meningococcal polysaccharide-Measles-Rubella V. 148- Hepatitis vaccine does is: a- Three times / year. b- Twice / year. c- Once / year. 149- Maximum dose of captopril is 150 mg / day. 150- Schedule of immunization of HBV is: a- Single does. b- Two dose. c- Three dose. d- Five days. 151- Maximum recommended dose of Ibuprofen is: a- 800. b- 1600. c- 2400. d- 3000.(3200mg) 152- Child of 10 Kg. paracetamol dose for him is: a- 100-150 mg. / 4-6 hours. b- 125-250 mg. / 4-6 hours. c- 250-500 mg. / 4-6 hours. 153- Maximum dose of Paracetamol is 4 mg. / day. 154- Maximum dose of Diclofenac sodium is: a- 50 mg. b- 75 mg. c- 100 mg. d- None of the above. 155- Vitamin A daily dose for the correction of deficiency Is 30,000 – 50,000 IU. Vitamin A daily dose for therapy Is 100,000 – 200,000 IU. 156- Insulin which can be given I.V. is: a- Regular type. b- 30 / 70 type. c- NPH type. d- None of the above. 157- One of the following insulin is given once daily: a- Protamine zinc insulin. b- Amorphous insulin. c- Neutral insulin. d- Regular insulin. 158- Source of human insulin is E-coli by: a- Biosynthetically by recombinant DNA technology using E-coli. b- Semi synthetically by enzymatic modification of protein material. c- A & B are correct. 159- When you store drug at low temperature you must consider the following: a- Storage of dusting powder below 0C causes the accumulation of granules. b- Storage of cream & ointment below 50C causes cracking. c- Storage of insulin below 0C causes aggregation of insulin. d- All of above. 160- Insulin is preserved at: 2 – 8 0C. 161- Drug is used for Leishmania: a- Na stiboglyconate. b- Na cromoglyconate. c- Mebendazole. 162- All these drugs are antibacterial except: a- Cefprazone. b- Lomifloxacin. c- Zalcitabine. 163- All these are natural estrogens except: a- Estradiol. b- Estrone. c- Estriol. d- Mestronol (Synthetic). 164- Estrogen: a- Reduces the incidence of coronary diseases in postmenopausal women. b- Can be taken for life time. c- Are ineffective when taken orally. 165- Co-trimethoxazole contains: Trimethoprim + sulphmethoxazole. 1:5 166- Which is not from quinolone group? a- Nalidixic acid. b- Eoxacin. c- Norfloxacin. d- Ciprofloxacin. e- Ciprofloxacin. [fluroquinolones] f- Ofloxacin. g- Sparfloxacin. Lemofloxacin. h- Aminosidine. i- Quinine. [antimalarial] j- H & I. 167- Quinolones are contraindicated in children because: a- Affect joints. b- Affect liver. c- Do not affect children. 168- Sumatriptan is used for: a- Treatment of migraine and headache. b- Angina pectoris. c- Control of epilepsy. d- Hypertension 169- All of the following for prophylaxis if asthma except: a- Ketotifen. b- Nedocromil sodium. c- Sodium cromoglycate. d- Salbutamol. (for treatment only) 170- All of the following are NSAH (nonsedating antihistamin) except: a- Loratidine. b- Cetrizine. c- Astemizole. d- Azotodine. 171- Which one of these symptoms does not occur with morphine? a- Respiratory depression. b- Constipation. c- Vomiting. d- Diarrhea. 172- Which one of these drugs is not used for acute pain? a- Naproxen. b- Colchicine. c- Ibuprofen. d- Codeine. e- Prednisolone. 173- Which one of these drugs is drugs of choice for Myxodema (hypothyroidism)? a- Thyroxin sodium. b- Carbimazole. c- Iodine. d- Propyl thiouracil. 174- Benzyl peroxide is a local treatment for acne vulgaris. 175- The drug of choice for treatment of amoebae is: a- Metronidazole. b- Chloramphenicol. c- Gentamycin. d- Tetracycline. 176- The steady state concentration of the drug in the plasma depends on: a- Direct proportion to the rate of elimination. b- Indirect proportion to the rate of elimination. c- Direct proportion to the rate of administration. d- Indirect proportion to the rate of administration. e. both b+c 177- What is the mechanism of action of vitamin K? Vitamin K has an essential role in the synthesis of coagulation factors by hepatic cells, and increases formation of clotting factors. 178- Elimination of digoxin is mainly by: a- Kidney. b- Liver. c- A & b. d- None of the above. 179- Drug physical dependence is as same as drug abuse. a- True. b- False. 180- What is difference between the following antifungals? Terbinafine = Local & systemic. Miconazole = Local & systemic. Amphotercin = Parentral only. Griseofulvin = Oral. 181- Terbinafine is used topically for: a- Fungal infection. b- Eczema. c- Candida sp. d- None of the above. 182- Amiloride as a treatment causes: a- Hyperkalaemia. b- Hypokalaemia. c- CNS disturbance. 183- Moduretic is a combination between: Amiloride + hydrochlorothiazide. 184- Give the indication of the following drugs: Gimfibrazole = for hyperlipidaemia. Cisapride = for gastro-oesphegyal reflux. Fluoxetin = SSRI as sedative serotonin reuptake Inhibitor = Carbimazole = hyperthyroidism. Imipramine = tricyclic antidepressant. Ipratropium bromide = anti muscarinic as bronchodilator. 185- Cefaclor is: a- 1st generation cepharosporins. b- 2nd generation cepharosporins. c- 3rd generation cepharosporins. 186- Teicoplanin antibiotic has similar effect on gram positive bacteria as: a- Vancomycin. b- Jamicain. c- Gentamycin. d- Kanamycine. 187- Which one is not tetracycline? a- Minocycline. b- Demeclocycline. c- Doxicycline. d- Clindamycin. 188- Tetracycline with Ca & Mg: Poorly absorbed compound from GIT. 189- Use of tetracycline in its expiry date make syndrome called: Fanconi syndrome. 190- Tetracycline when taken with minerals such as calcium, iron and aluminum forms a chelate which is: a- Inactive & poorly absorbed. b- Active & poorly absorbed c- Inactive & not absorbed d- Active & absorbed. 191- Which is not true with tetracycline? a- Broad spectrum bacteriostatic. b- Used for acne. c- Inhibits protein snthesis. d- Broad spectrum bactericidal. 192- Mesalazine is used for the treatment and maintenance of remission of ulcerative colitis. 193- Mention four lipid soluble vitamins. Vitamin A, D, E and K. 194- Imipenam (carbapenam) It is the first thiemamycin ß- lactam antibiotic. 195- All of these are antibiotics except: a- Cefopodoxin. b- Cefaprozil. c- Loefloxocin. d- Zaloltabin. 196- Metoclopramide is a dopamine antagonist acts centrally by blocking chemo-receptor Trigger zone & peripherally acts on GIT to be used as anti-emetic. 197- What is the definition of Bioavailability of the drug? Is the quantity of the active constituent of the drug absorbed by the blood through the intestine or any other route in a certain period of time? OR: Is the concentration of the drug in the blood in a ascertain period of time. 198- Bioavailability of the drug is: a- Rate of absorption. b- Extent of absorption. c- Rate & extent. 199- Biotransformation is: a- More lipids soluble. b- Less lipids soluble. 200- Omeprazole is: Losec (proton pump inhibitor) 201- Mention two diseases cause Edema: a- Renal failure. b- Congestive heart failure. 202- Example of drug-drug interaction: a- Warfarin - Aspirin. b- Warfarin - Phenobarbital c- Warfarin - Vitamin K d- Warfarin - Phenobarbital e- Heparin - Insulin g- INH - Insulin h- Digoxin - Spironolactone i- ACEI - Potassium sparing K. 203- All of these are the components of calamine lotion B.P. except: a- ZnO. b- Calamine. c- Sodium citrate. d- Bentonite. e- Sodium sulphate. 204- All of these are third generation cephalosporins except: a- Cefixime. b- Cefopodoxime. c- Ceftraxone. d- Cefotaxime. e- None of the above. 205- Which one is not benzodiazepine? a- Temazepam. b- Nitrozepam. c- Loprazolam. d- Clozapine. 206- Oral rehydrate solution is one of the following: a- NaCl + K citrate + Na citrate + glucose. b- Na citrate + KCl + NaCl. c- Na citrate + KCl + NaCl. d- NaCl + KCl + NaHCO3 + citric acid. 207- For hyperlipidemia we use: Gemfibrozile. 208- Gemfibrozile: a- Increases HDL & decrease triglysrides. b- Increases HDL & triglysrides c- Increases HDL & LDL. d- Increases LDL & triglysrides. 209- Drugs need monitor for their serum level: Amikacin Warfarin Theophyline Digoxin. All have narrow therapeutic index 210- For fluxacillin, all these statements are wrong except: a- It is better absorbed than Cloxacillin. b- It is taken by oral route only. c- It is activated by penicillinase enzyme. d- It is base stable. 211- What are the instruction for the patient take Metamucil or any other bulk foaming laxative as Bran, methyl cellulose and psyllum? 3 Methyl Glutoryl CoA reductase inhibitor.Increase heart rate. 219. b. 212. 216. b. d. Simvastatin. c.Ferrous fumarate.Ferrous citrate.Physiological and biochemical effect of the BODY on the DRUG.Ferrous sulphate.Bactrim (co-trimazole ) is: a.Ferrograde is: a.None of the above.Physiological and biochemical effect of the BODY on the DRUG. 213.Trimethaprim + sulphonylurea.Increase coronary flow. d. .The most common chemical structure of iron in drug is: Ferrograd (ferrous sulphate).None of the above. 220. 217.The adequate fluid intake should be maintained to avoid intestinal obstruction.Isomack 20 mg tablets taken twice daily at time interval between: a. d. 215.Keflex is: a. 214. d. b.1.8 am – 11 pm. b.Sympathomimetic drugs: a.Caciferol is: a.1st generation cephalosporin. 224.Mention drugs from HMG-CoA-reductase inhibitor.3 dihydroxy calciferol.2 dihydroxy calciferol c. Pravastatin and Fluvastatin.Physiological and biochemical effect of the DRUG on the BODY.Impenem (carbepenem) is: First thienamycin ß-lactam antibiotic. 222. c.Trimethoprim + sulphamethoxasole.2.All of the above.1.Ferrous gluconate.None of the above.Valtrex is: Acyclovir. c.25 dihydroxy calciferol.11 am – 11 pm. 223. 221.11 am – 8 pm. c. c. b. 218.HMG-CoA-reductase inhibitor is: 3 hydroxy.Pharmacodynamic means: a.Physiological and biochemical effect of the DRUG on the BODY.8 am – pm. b.Pharmacokinetics means: a.Increase blood pressure. b. I. b.Solution. 229. c.b. 233.Intrathecal means: Interjoint (spinal cord).I.4th generation cephalosporin. b.None of the above.3000 ml. 228.In a bottle we have NaCl 500 ml. it should be: a. 226. c. 225.None of the above.1500 ml.3rd generation cephalosporin d. c.G-ve.When drug is used for U. d. b.None of the above.I. c.None of the above.T. c.2nd generation cephalosporin c. 234. d. 232.Natural emulsifying agent: Gum acacia.One of the following is not NSAID: a.0.065 gm 230.Grain equal: 64.Voltic.Parafon. b. .2500 ml.30.Hypertension. b. 236.One of the following has faster systemic action: a.BOTH.Micromedex is: Computer system.Clonidine used in: a. and to obtain we should add what volume of H2O to get percent dilution 3 (H2O) : 1 (NaCl)? a.03.M.V.Emulsion. d. 227. 231.Olive oil + Water + Asq gives: a.3. b.0.C.Xefo.How much lidocaine for solution of 1/1000 to obtain 30 cc: a. c.Hypotension.S.8 mg = 0. 235.G+ve. b.Patient having constipation not to take: Morphine. Gut wall during absorption & I plasma stream.5% glycerin bicarbonate. b.Zantac contains: Ranitidine. 243.The drug of choice for head lice.Klacid is used every: 12 hours. b.Alcohol present in pharmacy as antiseptic is in concentration: 70% 241. 239. 250.Active while the free part is more active. a. 237. 244. 245. . c.Intralipids are: O/W emulsion.The drug transfers through cell membrane by: a. d. d. 240. b.One of the following preparations used as otic drops for dewaxing: a. 242.GIT & plasma.Imidazole.Isoptin is present in market in concentration: 240 & 80 mg. 248.Liver.All of the above.Isoptin is used in treatment of: Supraventricular arrhythmia.Primidon.Inactive while the free part is active.Glycerin magnesia. d.c. 246.All of these are precautions of becotide except: Used only at the attack of asthma. 238.Less active while the free part is active.Which is present in balms or liniments & not used inburns? Methyl Salicylate. b.Pyrithrins.5% alcoholic bicarbonate.Suppositories.Protein bounds to drug forming a compound which is: a.Disulfiram is used for: a.Prevention of conversion of acetaldehyde to acetic acid. c.Protection of lover cells from alcoholism. 249. d.Aqueous diffusion.DDT.The drug metabolism in the body occurs in: a. 247.Glycerin phenol. c. d.Gut wall during absorption. c.Treatment of chronic alcohol dependence. b. c. kidney and bowed mucosa.Highly active while the free part is inactive. 259. b.Sodium cromoglycate.Azelastine HCl. d. e.sedating anti-histamines: Loratidine – Cetrizine – Terfenadine. d. c.The main use of metronidazole is: a. b.Antihypertensive.Sisomycin.H2 antagonist. Aqueous diffusion is a type of Passive Transport across cell membrane 251.ß1 antagonist.F & G.Give an example of non.Roxithromycin.Muscarinic receptors. 256.Osmotic pressure.Tilade inhaler generic name is: a.Astemizole is a long acting non-sedating anti-histamine. d.A & B is correct. c.Decrease saliva. b. b.Peripheral action.A & B.Clonidine is used as: a. b. d. c.Budesonide.A drug which prevents the recurrence of migraine.Lipid dissolves. h. 255.Treat the side effect of anaesthesia. f.All of the above. d. b.Muscarinic receptors.Clarithromycin.All the following are macrolides except: a.Nedocromil sodium. d.b.Clindamycin. c. c.Erythromycin.Makes skeletal muscle relaxation as the effect of parasypathomimmetics. 258.Dopaminergic receptor.None of the above.Atropine is used as pre-anaesthetic to: a.Help the sleeping effect of anaesthesia. g. 253.None of the above.H1 antagonist.Metoclopramide gives anti-emetic effect through: a. d.Azithromycin. c. 257. 254.Anti amoebiasis.Apiramycin. . 252. c. e.New non-selective antihistamines act through: a. b. 263. b. c. d.Vancomycin.Cefuroxime. c. f.Cefprozil.Aminosidine sulfate. c.Rheumatic pain.Kanamycin.Carbimazole.Neomycin. 261.Cefexime. 266.Netilmicin.Tadenn.Which one is not aminoglycoside: a. 265. 264.Dysmenorrheal. b.Tobramycin.b.Angina pectoris. b. b.Benzyl peroxide is alcohol treatment for: a. d.Amikacin.Gentamycin. 267. c. d.Kanamycin.Neomycin.All these are broad spectrum cephalosporin except: a.Cefotaxime. c.Aminoglycosides are: a.Thyroxin sodium. . 262.Lomefloxacin.Neomycin sulphate. c. h.Tobramycin.Anthelmentic. d.Antimalarial.Streptomycin. g.Propyl uracil.Acne vulgaris.Which aminoglycoside antibiotic can be taken orally? a. 260.Zalcitabine.Mikacin. c.Antibiotic.Netillmicin.Cefopodoxime. d. b.Gentamycin c.All these are antibacterial except: a. d.The drug of choice in myxodema (hypothyroidism): a. d.Cefpodoxime. b. d. e.Teicoplanin antibiotic effect on G+ve bacteria similar to: a.Sisomycin. 269. d. Acetates. d.Has trade name Biltricide.b. 272. d.Patient with G6 phosphate dehydrogenase deficiency. b. d.Lymecyclin.Oral treatment of severe forms of psoriasis and disorders of keratinization. Guaiphenesin. 276.Pencillin.Prazosin. c.Leprosy.Antispasticity with spinal site of attack.A & B. b. c.Pencillin.Kanamycin.Give an example of drug inducing nephrotoxicity: Aminoglycosides as Gentamycin.Tobramycin.Cotrmazole (sulphonamide). Ipecauanha.Baclofen is used for: a.Meningitis. Creostesl Volatile oils. 271. c.Praziquentel used for Billhariasis: a. 274.Methyldopa. . the drug may cause haemolysis: a.Which of the following has no vasodilating effect? a. 270.Enalapril. b. d.None of the above. b.Ketoconazole.Expectorants are: Iodides.Caused loss of intercellular calcium of the worm. c.G-6PD deficiency patients must not take: a. b.Tuberclosis.Acitretin is used for: a.Paracetamol. 275.Tuberculosis. Bicarbonates. b.Sulphonamide. c. Chlorides.None of the above. Squil. c. 273. 268.Hydralazin.Give two side effects of aminoglycosides: Nephrotoxicity – ototoxicity. d. Glicazide = Diamicron Glipizide = Minidiab Tolbutamide = Rastinone.Glucocoticoids (any steroid hormone promotes gluconeogenesis.Generic and trade names of anti-malarial drugs. 281. b.Long duration.Pentobarbital (often used as pre medication in children) differs from phenobarbital in: a. Alverine = Spamonal.To lower plasma Ca concentration in some patients with hyper calcaemia (excessive calcium in the blood.Treatment of Paget disease (hypercalcemia associated with pain).Bronchial asthma.None of the above. b. Glibenclamide = Daonil & Euglucon.e.Paracetamol. Diclofenac sodium = Voltaren. Cloroquine = Malarex & resochin.A & B. d.Faster in action.Generic and trade names of sulphonylurea: Chlorpropamide = diabenase. Ketoprofen = Profenid.Generic and trade name of NSAIDs: Acetyl salicylic acid = Aspirin. Primaquine = Primaquine. deafness. Ibuprofen = Brufen. Oxyphenonium = Anternyl. b. the formation of glucose and glycogen from protein) used in: a. Propantheline bromide = Probanthine.c. c. 283. i. c. Mebeverine HCl = Duspatalin. 279.g. 282. 277.Dexamethasone. Diflunisal = Dolobid. Indomethacin = Indocid. indogesic and Rothacin.Generic and trade name of antispasmodic drugs: Hyoscine N butyl bromide = Buscopan & Scopinal.Relieving some neurological complications e. Glimipiride = Amaryl.Addison disease. Naproxen = Naprosyn. 278.Use of calcitonin: a. Fenbufen = Cinopal. . Acetohexamide = Dimilor. d.All of the above 280. Khellin = Lynamine. Pivampicillin = pondocillin. 291. 285.Use of gentian violet (crystal violet) : a. Isotretinoin = Roaccutane. 284. b. Methodone.Pyremethamine + Sulfadoxine = Pansidar. 1% according to U. Enteric coated tablets: Are dissolved in the intestine and not affected by the stomach juices e.What is the concentration of mercurochrome solution? 2%. Omeprazole = Losec. Morphine.5% according to B. . Sildenafil = Viagra. 287.S. 288. Acarbose = Glucobay. Dextromethorphan.Antiseptic. 290.The concentration of crystal violet paint is: 2. 289. c. b.What is the difference between retard and enteric coated tablets? Retard tablets: Are coated with a thin layer of different kind of coating agent which make the active constituent sustained release. Isobarmiline.Skin disinfectant.Sustained release tablets depend on: PH of stomach.Ready programmed & no influence of the body fluid. Antifungal 286.Controlled released drug delivery depends on: a. Codergocrin = hydergine.All of the above. Passes the stomach & releases in the intestine.P.Enzymatic reactions. Bufexamac = Droxaryl. Hexoprenaline = Ipradol.g. d.P. 1980. Phlocodein. Baclofen = Lioresal. Anthelmintic. Orlistat = Xenical.Give six generic names of cough sedatives: Codeine.List of the trade name of the following: Pindolol = Visken. 1985. Acitretin = Neotigasone. how to arrange: a. b. d. b.A patient of 10 kg is given a Paracetamol one teaspoonful every 4-6 hours. b.Contains store.Go to a hospital. d. 297.Give him another drug. d.This is normal side effect.Patient sex.Stop the drug.A child of weight 10 kg.If you have prescription containing Inderal & the patient is wheezing. d.Stomach Ph.Go to doctor. c.Patient take phenytoin and his hair be less growth. c.Pharmacy of central hospital is: a. c. you should call the doctor to tell him: a.None of the above.Arrange contraception.All of the above.Central pharmacy only.Consult doctor.Give her the drug directly with no questions. b. no proper time) may be because the dose regimen is not easy or the dose is high or the side effects are clear. d.There is no need to call the doctor. b.Send the wife to the family doctor.The dose is very high. 296. b.When newly married don't want children. 299.Treatment with an anti-arrhythmic drug depends on the following except: a. You advise him: a.If she is pregnant.Send the wife to her mother. d. c.Body fluid interaction.Give him a medicine.Doctors advise.Period of medication.Ro-Accutane is prescribed to patient who is women 22 years old. what is your . c. c. 292. c. 298. 294.Ignore the case. what can you advice him? a. Accidentally swallowed 10 tablets of aspirin and his father came to you.The dose must not exceed 180 mg daily. Patient dose not take medication as the physician's advice.Type of medication. 295.The dose is not sufficient.c.What is the meaning of poor patient compliance? The patient did not take the medication properly (no proper dose. you ask? a. 293.None of theabove. 300. b. both ears et = and b. italicization and punctuation in abbreviations. 301.What is the meaning of the following? POM = Prescription Only Medicine.m.d.P.A. or aa = of each comp.6.m. or disc.C. aa. = right ear disp. ECG = Electro Cardio Gram.Do you take any other antihypertensive? c. = ampoule d.Safe and nice formulary. = Glucose-6-Phosphate dehydogenase.or c = with ft = make cap or caps = capsule g or GM =gram cp = chest pain gal = gallon D. = in water BP = British pharmacopeia fl or fld = fluid BSA = body surface area fl oz = fluid ounce c. described as written GI = gastrointestinal . = discontinue a. = dispense ad lib.d. Q6H = every after 6 hours.c. = water D5W = dextrose% in water a. The following list shows the abbreviations that are not often encountered by pharnacists: A. = left ear elix = elixir asa = aspirin e.Patient has hepatic disease & type II diabetics take: Rosiglitazone or pioglitazone (Avandia. b. 304. Considerable variation occurs in the use of capitalization. 303.d. = twice daily ex aq.p.dc.SNF is an abbreviation for: a.Do you need syrup or tablet? d. = before meals dil = dilute ad = to. = each ear.s. to be divided a. G.i. Glustin) 302.Saudi national formulary.Seasonal national formulary. up to D.u.W. BID = Twice Daily.advice? Call the doctor. what do you ask him? a. = morning dl or dL = deciliter amp.Which product of KCL do you need? b.t. c.What is difference between QID & Q6H? QID = 4 times a day.A patient has a prescription of Enalapril + KCL. = compound...D. BPC = British Pharmacopial Codex. At pleasure freely div. = divide. 305.None of the above. = as directed a. = give of such doses ante = before DW = distilled water aq. compounded a. = every hour Noct.n. = powder ml or Ml = milliliter Pv = vagenal use μl or μL = microlitre q. or o.4 hr.S. = left eye IVP = intervenous push OTC = over the counter IVPB = intervenous piggyback o. = do not repeat H = hypodermic NPO = nothing by mouth h or hr. = injection o. Desk Reference μ = Greek mu p.u. = by mouth M = mix Ppt = precipitated M2 or m2 = square meter Pr = for rectum Mcg.s.I.o. = as needed mEq = milliequivalent Pt. cubic centimeter gr or gr = grain Gtt or gtt = drop. mcg or μg = microgram Prn or p.Cc or cc. = every 4 hours Prepared by Dr. = pint mg = milligram Pulv. = after meals Lb = pound PDR = Physicians. drops Non rep. in the night q.. = each eye.s. M U Khan 400 Questions: 1.c. =every day N.r.F. = ounce I or L = litre p. = National formulary q. = right eye every day IV = intervenous o. = night. = hour N.d.d. = every N & V = nausea & vomiting q.Inderal is : a-similar in action to ergotamine .h. NS = normal saline h. = at bed time ½ NS = half-strength normal saline IM =intramuscular O = pint Inj. both eye K =POTASSIUM oz.The major action of sodium chromoglycate is:A-mast cell stabilization b-bronchodilator c-prostaglandins modifier d-leukotrienes modifier e-non of the above 2-The action of histamine is : a-capillary constriction b-elevation of blood pressure c-stimulationof gastric secretion d-skeletal muscle paralysis e-slowing the heart rate 3-One of the following antibiotics is resistant to penicillinase : a-penicillin V b-penicillin G c-floxapen d-ampicillin e-amoxicillin 4. Which of the following is NOT betamethasone side effect ? A-cataract b-hypoglycemia c. Oxypurinol also inhibits xanthine oxidase.The Latin abbreviation for " After Meals " is : a. c.a.a.Rifampicin is indicated for treatment of : a-impaired fat absorption b-pulmonary emboli c-tuberculosis d-neoplastic disorders e-psoriasis 6.c. 13.q. 10. e. 9.antiinflamatory agent d-antipyretic agent e-agent which increases renal tubular reabsorption Allopurinol inhibits xanthine oxidase. d.c.a.c.i.t.c.p. b.c. 8. e.a.a.p.n.i.c. motility d-could be used in pregnant women if need e-all of the above 11. decreased renal tubular transport of uric acid.o.c.a.a.Allopurinol is used as : a-analgesic agent b-uricosuric agent c.Erythroped A : a-is effective against G +ve Cocci b-is a macrolide antibiotic c-canincrease g. and then the side effect of increased tubular reabsorption of calcium.b-similar in action to tubocurarine c-used as an antihistamine d-pure b -adrenergic receptor blocker 5. b.c.p. skeletal muscle weakness d-sodium retention e.c.c.c.The latin abbreviation for " Four Times Daily " is : a. lowered .i. reducing the conversion of hypoxanthine and xanthine to uric acid and resulting in direct inhibition of purine biosynthesis due to elevated oxypurine concentration (negative feedback).i.c. b. c.For the treatment of anaphylactic shock use : a-salbutamol b-diphenhydramine c-acetazolamide d-epinephrine e-aminophylline 12. c. d.Which of the following is non selective b1 blocker ? a-labetilol b-terazosin c-clonidine d-captopril e-verapamil 7.The latin abbreviation for " Every Night " is : a. So anyway you have dramatically decreased uric acid concentrations. d.c.c.d. e. Which of the following are causes of oedema? a.resistance to infections 14.Respiratory acidosis is due to : a.Adenosine is used for : a-ventricular arrythmias b-atrial bradycardia c-supraventricular tachycardia d-supraventricular bradycardia e-non of the above 19.O2 removal b.SA node c-pukinje fiber d-internodal pathways e-non of the above 18.a and b e.Which of the following is NOT colloid solution ? a-albumin 5% b-ringer`s solution c-dextran d-beta starch e-albumin 20% 23. b and c . by bacterial cell wall during there growth) a-endotoxin b-exotoxin c-antibiotics d-cytotoxin e-non of the above 26.The heart`s dominant pacemaker is : a. increased capillary permeability d.A disease which is due to viral infection : a-poliomyelitis b-rabies c-chicken pox d-herpes e-all of the above 15.marked tachycardia d.Adenosine P produces which of the following : a-facial flushing b-dyspnea c. b and c 20.Myocardial muscle tissue property to generate electrical is : a-inotropy b-chronotropy c-automaticity d)contractility e-none of the above " Dromotropic effect" 17.non of the above 16.Which of the following is responsible for buffering a-magnesium b-chloride c-bicarbonates d-potassium e-troponin 21.In treatment of shock .the amount of water in adult male is about: a-25% b-60% c-80% d-10% e-17% 27.nicotinic antagonist d-nicotinic agonist e. none of the above 22.The mechanism of action of atropine is : a-muscarinic antagonist b-muscarinic agonist c.CO2 retention e.AV node b.O2 retention c.The term shock signifies : a-hyperperfusion b-hypoperfusion c-tachycardia d-bradycardia e-non of the above 24.Increase hydrostatic pressure b. which of the following should be considered? a-airway control b-IV of crystalloid solution c-dopamine to support blood pressure d-monitor heart rhythm e-all of the above 25.CO2 removal d.Which of the following is released by bacterial infection?(….Decrease oncotic pressure c.a and b e.a .a . Which of the following is NOT true about infiximab a-IL-1 blocker b-used for treatment of severe rheumatoid arthritis c-may increase risk of infections d-administered as IV infusion e-postadministration reactions include fever & chills 35.Patients prescribed non reversible monoamine oxidase inhibitor should be advised not to consume food containing tyramine because this combination causes: a-postural hypotension b-hallucinations c-anaphylactic shock d-muscle weakness and tremor e-acute adrenergic crisis including sever hypertension 29.considered anticoagulation with warfarin d.a and b e.Which of the following is true about surgical prophylaxis ? a-it is given to treat surgery associated infections .In the treatment of osteoporosis which of the following is NOT true? a-alendronate should be taken 60 min. with an initial diagnosis : a-slow ventricular response using verapamil b-start lidocaine infusion c.Which of the following is NOT a risk factor for osteoparalysis? a.b and c 37. b and c 36.R. before breakfast b-Ca and vit.28.a and c e.A disease modifying drugs in rheumatoid arthritis: a-gold preparations b-hydroxychloroquine c-methotrexate d.A patient who is admitted through the E.a .Early symptoms of aspirin poisoning are : a-lethergy & fatigue b-skin rash & headache c-throbbing headache & dizziness d-fluid retention hypotension e-ringing in the ears & blurred vision 34. D are essential c-hormone replacement therapy should be considered d-outcome should be assessed with periodic bone density e-raloxifene is selective oestrogen modulator 31.minimal exercise b-low calcium intake c-male gender d-family history e-minimal exposure to sunlight 33. which is NOT true? a-they have lower risk gastric adverse reactions bgood evidence about their effectiveness c-cardiac toxicity is a recent concern of this class dthey usually administrated twice daily e-combination with non selective agents give more effective action 30.Which of the following is the first choice in acute gout? a-allopurinol b-indomethacin c-colchicine d-probencid e-sulfinylpyrazone 32.Concerning COX 2 inhibitors . b and c 41.85% c)10% d) none of the above 30gm--------------1%(1/100) ------------=0.a and b e.1. molecular weight of NACL=23+34=57 So. 70gm-------------X%--------------=1.a .1-5 mg b. In 1 grams So. mucillages and collodions e-enemas . the con.5%(2.52 g of NaCl exactly 2000 ml. b-essences .3gm 40gm--------------2.6 u / kg / day split 2/3 a.When dosing insulin which of the following is true? a-initial dose 0.b and c e. b and c 42.60 d-3.b and c 39.3 So. Result =1. d-syrups .a and b e.307 .15-60 mg c.3/70=1.The usual daily dose of phenytoin in the range of: a. What is the molarity of this solution? a.300-600 d -should be continued for 7 days after surgery e-all are true 40. liniments and spirits 43.00 x 10 -4 e-1. douches and irrigation soln.A solution is made by dissolving 17.857% 42.3. Mole=17.6x10 -4 Morality=mole/volume (L) Mole=molecular weight of subs.b-it is given to reduce the possibility of surgical site infection c-should always be given regardless type of surgery d-should be continued for 7 days after surgery e-all are true 38.HBA1c d.When diagnosis of diabetes to be considered : a-WBC count with differential b-oral glucose tolerance test c.These are non aqueous pharmaceutical solutions: a-otic soln.5/100) --------------=1gm So.a .15 c.Goals of diabetes mellitus management include : a-reduce onset of complications b-control symptoms of diabetes c-near normal glycemic control and HBA1c d.33 b.What first line agent may be considered for an obese type 2 ? a-glyburinid b-insulin c-metformin d-nateglinid e-repaglinid 41-30gm of 1% hydrocortisone mixed with 40 gm 2.m b-regular NPH ratio is 1 : 1 or 1 : 2 c-dose may need to be increased during acute illness d.5% hydrocortisone what is the concentration of the resulting solution? a) 3% b) 1.52/57=0. . collodions and elixirs c-gargles .m and 1/3 p. mouth washes and nasal soln.0. Propranolol is often prescribed with hydralazine to a-reduce the reflex tachycardia b-prevent the accumulation of hydralazine.Which of the following is NOT correct ? a-glitazones are ineffective as mono therapy b-GIT disturbance are common side effects of glycosidase inhibitors-a c-start with small dose of oral agent and triturate up to 1-2 weeks d-life style modification should not be enforced if an oral agent to be started e-lispro is rapid acting insulin to be dosed immediately before meals 48.When a CNS depressant is prescribed.The ability of a liquid to dissolve is : a-hydrophilicity b-miscibility c-immiscibility d-solubility equilibrium 47.a and b e.307/2=0.153 44.References to check compatibility of drugs in parentral administration: a.The drug of choice to control pain during acute myocardial infarction is : a-naloxone b-pethidine c-morphine d-celecoxib e-naproxen 54.A 4 mg dose of lorazepam administered to a adult will act as : a-analgesic b-hypnotic c-diuretic dantihistaminic e-anticonvulsant 53.In CHF management the following is not correct: a-ACEIs such as lisinopril improves left ventricular function and reduces mortality b-blocker such as carvedilol may have beneficial effect in selected patient c-spironolactone should be avoided because of the great risk of hyperkalemia d-non drug therapy includes appropriate fluid and dietary sodium-restriction e-symptomatic improvement is one of the major assessment criteria for proper therapy 49.JAMA 50. d-prevent edema e-increase absorption of hydralazine 46.What is a major contraindication to the use of an OTC sympathomimetic drug : .b and c 51.Which of the following is NOT a primary literature a Journal of pharmacy practice b-applied therapeutics & clinical use of drugs c-new England Journal of medicine d-Loncet e.MERCK Index b-handbook on injectable drugs c-micromedix d.Which of the following drugs exhibits dose dependent pharmaceutical therapeutic doses ? a-Na valproate b-phenytoin c-lithium d-quinidin e-carbamazepine 45. Morality=0. which of the following is NOT taken at the same time? a-analgesic b-verapamil c-aspirin d-diphenhydramine e-orange juice 52. c-prevent systemic lupus ( SLE ) due to hydralazine.So. M.K+ b.Na+ c.V.V.There is positive evidence of human fetal risk but the benefits of use in pregnant woman may be acceptable despite the risk 56.Correct method of parentral administration of potassium is : a-fast I.When considering drug therapy for hypertension.05 ( milligrams ) c.0.Which of the following is NOT used in theophylline toxicity management : a-symptomatic control of seizures with benzodiazepine b-activated charcoal to enhance elimination c-b blocker for tachycardia d-control vomiting with metoclopramide e-methylphenidate to reduce excessive sedation 63.V. injection d-IP(intraperitoneal) injection 58. injection c-I.Which route of administration would provide the most rapid onset of action response to morphine ? a-oral b-S.fetal risk NOT demonstrated in animal studies but there are no controlled studies in pregnant women or animal reproduction studies have shown an adverse effect that was NOT confirmed in controlled studies in women during trimester c-either animal study have revealed adverse effect on the fetus and there are no controlled humanstudies or studies in animal and women are not available d. d-I.a and b e. c-I.M.ACEIs are recommended in pregnant women 62.The long term administration of thiazide diuretics requires : a.a and c 61.CO3 e. which is true? A-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-beta-blokers should be avoided in asthmatic patient e.Regarding the use of ACEIs : a-associated hypokalemia could be avoided by giving K-supplement .controlled studies fail to demonstrate a risk to the fetus in the trimester and there is no evidence of risk in later trimester b.What advice would you give to a patient prescribed rifampicin? a-take this medication with food or milk b-avoid multivitamine preparations during treatment c-avoid taking paracetamol during treatment d-possible discolouration of skin is of no importance e-this medication may cause discolouration of urine 57.acetate 60.C. injection b-slow I.0005 g d. e-rectal 59.Fifty micrograms equals: a-50000 ( nanogrames )? b.Ca++ d.a-gastric ulcer b-uncontrolled hypotension c-severe asthma d-rheumatoid arthritis e-hypertension 55-Category C in FDA for drug used in pregnancy : a.0. Role of carbidopa in treatment of Parkinsonism.naprosyn d.propranolol b.dextrose 5% c.growth hormone c-adrenocorticosteroid hormone 76.95 ml of MGCL dissolve in 100 ml water 68-The following is NOT characteristic of solution: a-thermodynamically stable b-composed of two or more component that exist in one phase c-homogenous d-the solvent and solute can be separated by filtration e-solute doesn`t precipitate as time passes 69.myocardial infarction 75.insulin d.which of the following need filtration before IV infusion a.Serotonin reuptake b.first pass b.to increase duration of lidocaine in anesthesia a.All the following anti -inflammatory.Suspension e.5HT1 antagonist 70.b-effective in reducing proteinurea in diabetic patient c-most common side effect is chronic dry cough d-a good first line treatment for hypertensive diabetic e-dose should be started low and triturated gradually upward in need 64.which hormone are secreted from posterior pituitary gland a. : supress activation of the heart so decrease work of the heart by decrease cardiac output 71.psoriasis c.oxytocin b.emulsion 74-azaleic acid used in a-acne b.mannitol b.sevredol 73.succinyl choline c.When drug absorbed through GIT then go to liver and excreted this process called a.aspirin c.The antimalarial to avoid in glucose-6-phosphate dehydrogenase deficiency : a-primaquine b-quinine c-chloroguanide 66-HOW can prepare 100 ml of 12% MgCl by taking? a-12ml of MGCL dissolve in 100 ml water b-12 mg of MGCL dissolve in 100 ml water c-12ml of MGCL dissolve in 1000 ml water d-90.drug distribution 72.drug metabolism c.dopamine agonist c. analgesic effect except a-ibuprofen b.Role of B-blockers in angina.epinephrine .Dopamine antagonist e. a.Regarding treatment of digoxin toxicity: a-verify time of last time b-check Mg and K levels and correct if needed c-monitor ECG d-no antidote for digoxin e-supportive care 65.Decrease dopamine METABOLISM in peripheral vessel d.5 ml of MGCL dissolve in 100 ml water e-. has amino glycoside antibiotic c-decrease GIT motility d-should not be used in pregnant woman if need e-could be used in pregnant woman if need 82-the optimal size for ophthalmic drops:.b 79-which of the following cause metallic taste a..Omeprazole used to: decrease gastric acid secretion .Hemoglobin test d-. 88.which of the following are characteristic for Erythroped a.lidocaine b...decrease in liver enzymes function c....Metronidazole 80..cimetidine c..A and B 78-monitoring for dose in elderly patient: a. rifampicin 90.which of the following are characteristic for Erythrosine: a-not effective against G+ve cocci b.1 November b.dosage form d.reabsorption is high d.if patient take Gentamicin for a time which of the following need monitoring test a.excretion in kidney decrease b..furosemide c.. 91-which of the following is antiarrhythmic class Ιa:a.spironolactone d..sex c....age b.d. test c.Atropine 77.which of the following has aldosterone antagonist effect a.not macrolide antibiotic c.amiodarone d-Quinidine .can increase GIT motility d-can not used in pregnant women if needed e.< 10μg 83. (ADHD) 84-if packaged are written for expiry November 2006 it mean that can be used till a. 87.liver enz...captopril b.Drug absorption depend on a...none of the above 81.. 85-The mechanism of action of Buspirone through a-5HT antagonist b-GABA agonist c-dopaminergic agonist d-dopaminergic antagonist 86.metabolism is high e.propranolol c.hydrochlorothiazide PEPTIC ULCER 89-which of the following change color of the urine to red nitrofurantoin .A ..Drug state e.amiloride b..metformin d-..Amphetamine is used in: defect of awareness in the brain of children.Nitroglycerine introduces: coronary vasodilatation.not effective against G +ve cocci b..31 November As November consists of only 30 days.serum creatinine level b. Antiarrythmic drug class Ιb produce its action through:a.decrease phase 4 depolarization d.second generation cephalosporin c. 98.Chiral molecule mean:a-dipole moment b.Bambuterol is used in:treatment of asthma.give one drop to right eye twice daily b.co-trimoxazole d.″ om″ is abbreviation for at morning.ophthalmic prescription are written through following ( gtt tod Bid ) this mean:a.Class ΙΙ antiarrythmic drugs produce its action through:a.Gamciclovir.fosinopril c.adrenergic receptor blocking e. disintegration 108-Benzodiazepine mechanism through:binding δ subunit of GABA-A receptor.amoxicillin c. 95-lovastatin produce action through:HMG-co reductase inhibitor. zinopril or zestril is found in :a-captopril b.Ketoconazole d.shorten action potential 93.decrease rate of phase 0 depolarization b. 106-diazepam used in:.first generation cephalosporin b.ramipril d-Lisinopril 97.increase phase 3 repolarization d. 104.92.shake well and then give one drop to left eye twice daily d.increase phase 3 repolarization c.shake well and then give one drop to right eye twice daily.solubility c.suppress phase 4 depolarization d. 102.third generation cephalosporin d.ceftazidime is:a.ciprofloxacin 105. 100.Which organism are the cause of traveler diarrhea:E-coli. 99-tegretol is used in ttt of:status epileptic. seizures.Drug used in ttt of traveler diarrhea:a-ampicillin b.shorten phase 3 repolarization 94.lisopril .anxiety.fourth generation cephalosporin 103.adrenergic receptor blocking e. .give one drop to left eye twice daily c. 107-solid to be reduced in size before dissolving called:. d-optical activity.Nystatin b.Streptokinase is used in ttt of:pulmonary emboli. 96.decrease rate of phase 0 depolarization b.chelating prep.Amphotericin c. 101-all the following are antifungal except:a. losartan c.C 124.vincristine . 110. d-external prep.moist heat 114-which of the following need serum level monitoring with Quinidine:a-Digoxin b.physical Rx b.APTT d.warfarin monitoring therapy by:a.lipid profile 111-in ovulation phase which hormone is predominant:a-FSH b-LH c. vinblastine . 128-pt CHF take digoxin and hydrochlorothiazide with ray arthritis which of the following drugs can be used :a-cortizone b-hydrocortisone .k b-1/k c.693k 123-adsorption are affected by the following except:a.Digoxin used in ttt of CHF as has:+ VE inotropic effect 126.cholinergic agent c.make complex with anticholinesterase and inhibit its action 121-tetracaine is used as:a-opoid pain b.109-Vinca alkaloids produce anticancer drugs :.. c.parentral prep.vitD metabolite c.reversible e – B.which of the following has catharitic side effect:a.oral susp.dry heat c.chemical Rx c.a.irreversible d.2k d.Ecothiophate mechanism through:a-binding to muscarinic receptor b. 120. intake d.hydrochlorothiazide 118.calcium sulphate 119-normal water can be used in:a.phyochromocytoma b.sod.PPM mean:.aluminum silicate b.albutrol c-ampicillin d-Diazoxide 115.minoxidil c.Propranolol d. constipation c. vindesine.nausea .neuromuscular blocker 122-half life for first order kinetic:a.skeletal muscle relaxant.0.filtration b.skin rash 116-drug used for ttt of migraine and HTN:a-clonidine b.INR (international Normalize Ratio) b. vomiting b.cholinergic antagonist c.a.Charcoal produce its action through:a.hypoglycemic effect d. 113-most common process for sterilization:.platelet count c.adsorption 125.ischemic damage e.spinal anesthesia d. b-ophthalmic prep.hydralazine b.pindolol datenolol e.can't be used as monotherapy in mild HTN:.hydralazin 117.progesterone and LH 112-vencuronium is used as :.magnesium sulphate c.………….part per million OR million part 127-all are causes of 2ry HTN except:a.side effect of epinephrine is:.a.headache .progesterone d. cardiac toxicity b.pindolol c.Daily recommended dose for folic acid 146.prep.labetolol d-Captopril 138-Doxorubicin side effect :a.one of the following is member of phenothiazines group prochlorperazine 144-primidone is prodrug for ( antiepileptic drug ).Pharmaceutical alternative d.Very small molecule (1 part ) soluble in 10. containing coal tar 30 part & petroleum 15 part adeq.salbutamol is used as:bronchodilator 136-podocodeine is used in dry cough 137-which of the following not used in emergency HTN:a.c-fluticazone d-prednisolone 129-if a drug has the same active ingredient like other drug but not contain the same inactive ingredient this mean :a.arrhythmia 139.Which of the following is alkylating agent and anticancer a-vinblastine b.which of the following not used in ttt of asthma:a. C in male :a-30mg/day b-50 mg/day c-90mg/day d-200 .slightly polar 143.slightly soluble C-immiscible d. 134-Alteplase is used:.non polar c-soluble d. to 150 part what conc.insoluble 142-benzoil not soluble in H2O but soluble in benzene in 25◦ c a.B2 agonist b-B2 antagonist 140.miscible e.polar b.000 part of water a.cisplatin c.Bioequivalent b-pharmaceutical equivalent c. in 150 ml:7.B 130. of coal tar in 500 ml:15 parts in 150ml X parts will be in 500ml.Beta starch e.postural hypotension d.5x150/5 =225 mg 131.vicristine 141.albumin 20% 133-sildenafil is found in Viagra.5 mg in teaspoonful what will be conc.Daily recommended dose for vit.Dextran d.furosemide b.Cyclophosphamide d.conc. 145.A.5 mg________ 5ml x? mg________ 150 ml x mg=7.therombolytic 135. of a drug is 7.fairly soluble b.nephrotoxicity c.insoluble e. x=15*500/150. x=50 parts of petroleum 132-which of the following is not colloid A-kerbs solution b.albumin 2% c. constipation 154-which of the following narcotics not used today:a.Heparin can be monitored through :a.IM b.Buffering agent used in ophthalmic drops to:decrease irritation to eye and increase stability 151.fat b. gel .IV c. daily dose for paracetamol is ( 4000 mg ) 149.half life ↓ c.renal failure b.G+ only b.morphine b.hepatic pt c.protein 156-which of the following dosage form are famous:a.b 161-3rd generation cephalosporin has:a. gel.IV infusion 160.dizziness e.heroin c.All the following are side effect of oral contraceptive except:a-hypertension b-weight gain c.APTT b.400 mg/day 147. solution .Sodium picosulphate is used as laxative 152.INR c-PT d-IM 159-Enoxaparin is administrated:a.mg/day e.reduce particle size b.b 164-when use liquid or oint.oint .side effect ↑ d.G+ve .action ↑ e. solution b.400 mg/day 148.increase particle size d.in case of hepatic or renal failure which muscle relaxant is recommended :.G-ve only c.S. C in female :.Asthmatic pt 153.lipid e.Cis-Atracurium 158.type of solution c-analyzer d.GABA receptor 166.half life ↑ b.increase surface area c.NSAIDs produce action through:- .a. to dissolve the solid it is called :levigation 165.Ergot alkaloids is used as antineoplastic 150.muscle c. b.a.if drug protein binding increased or decreased:a. oint . d.decrease surface area e-A&B 163.a-30mg/day b-50 mg/day c-90mg/day d200 mg/day e.drug stored in the body in:a. G-ve 162-solubility enhanced through :a.nicotine d.Digoxin toxicity increase with:a. oint. gel 157.oint. gel e.Hyperglycemia d.phenytoin act on :.solution .C.Daily recommended dose for vit.codeine 155.max.determination analysis of solution depend on : a-nature of solute b.solution.connective tissue d. sustained release dosage form is used to a-increase half life b.sedation 168.insoluble 174.drug after metabolized in liver it will become:a-polar b.reserpine 170.nausea .diltiazim classified as : .non polar c.anticoagulant b.pound = 0.repolarization to ca out 176. abdominal disturbance e.a.infusion of hypotonic solution in blood cause : a) shriniking of blood cell b) hemolysis c) hyperglycemia d) hypoglycemia e) b + d 181.lipophilic d. 173.infusion of hypertonic solution in blood cause : a)shriniking of blood cell b) hemolysis c) hyperglycemia d) hypoglycemia .……………………….twice daily ctwice weekly d.increase cardiac contractility..ampicillin b.antibiotic d.453 kg 172.which of the following cause depression :a.loading dose definition 175.which of the following not characteristic of theophylline:a.pyridoxine e.quinidine 169.every week 177.decrease prostaglandin synthesis 167.convulsion d.excitability 180.relaxation to bronchial smooth muscle b.anti asthmatic 171. CO c.antiplatelet c.every day b.calcefirol 179.electrical property which produce impulses called : a-conduction b-automaticity c-velocity d.in phase 1 in muscle contraction occur:a-depolarization for k in b.drug have low therapeutic index c.thiamine c-riboflavin d.half life of drug is 7 days HOW can taken:a.PREVOC is trade name used as:.what is drug of choice in ttt of bronchospasm/asthma:a-salbutamol (albutrol ) b-theophylline c-propranolol d-esmolol e. Ca channel blocker 178-B carotine is precursor of : a-retinol b. 182...good lipoprotien.lipid d-carbohydrate e-.C d. if 5 one tspfull doses contain 7.. 193.A&B 191.hydralazine c.homogenous b.denaturation will happened in body for which compounds? a-penicillin b. 189.increase rate of absorption b. X gm =15x2000/75 =400 gm 183.infusion e.drug induced lupus like syndrome is associated with antihypertinsive ? a-minixidil b.S..How gram needed from drug .About definition of first pass effect .5 e) 1500 25% 184.transdermal 187.5 c) 500 d) 1.increase pka d...dosage form of nitroglycrin when used in malignant hypertension ? a-IV b-IM c..major metabolism proccess in GIT is:a-hydrolysis b.4 (X) 100% 15 (2000gm) 10% 75 2000gm -------------75 X gm -------------15 So.transport fatty acid c..1 gm in ml .increase biotransformation c.metal used in rheumatoid arthiritis : gold 192.heterogenous . if 0.true solutions another name is:a. 185....oxidation d-conjucation 186.inhibition of converting angiotensin I to angiotensin II 190.0005 b) 0..Hypothyroidism cause :a-weight gain b.low density lipoprotein(LDL) act as : a-carrier cholesterol in plasma b.dioxide d-nitroprusside Na e..hypoglycemia c-low body temp d-.5 gm of drug ? a) 0.ACE I mechanism of action as antihypertension ??? . it increase with:a.....How gm of substance X must added to 2000 gm of 10% substance X solution in order to prepare 25% of substance x solution a) 10000 b) 400 c)40 d) 10 e) 0...proteins c...acetylation c.acebutol 188. mechanism of action of antipsychotic drug : Dopamine receptor inactivation 205.B + C 197. 50% of substance X solution . what is not recommonded? a-stop digixin administration b-phenytoin administration c-give lidocaine d-give digoxin immune fab e-electrical cardio 200. 195-most of drugs are : a-Weak electrolyte b-Non electrlolyte c-Non ionic d-Strong electrolyte e-B+ C 196-90% of substance X solution .5: 9 e. how mixing both to give 80% of substance X solution ? a.suspension 194-about ophthalmic preparation as single dose which is false:a-sterile b.hormone excreted from adrenal cortex : a-Growth hormone b-Primary product c-mineral corticoids (eg.In digoxin induced arrythmia . aldosterone) d-glucocorticoids (eg.purified c-should contain preservative d-……….primaquine d-vancomycin 198-digoxin differ from digitoxin : a-Half life b-Excreted hepatically d-Excreted unchanged in urine 199.ACE inhibitors are contraindicated in : bilateral renal artery stenosis ..c-emultion d. cortisolndrosterone) e-weak androgens (eg. dehydroepiandrosterone) f=c+d+e 202.all of following are side effects of methotrexate except : a-Bone marrow depression b-Alopecia c-Nausea and vomiting e-Drive sex gland 204.which is not asthma properties : a-Bronchodilator bBronchospasm c-Increase mucous secretion d-Chest pain 201.3: 1 b-1:3 c10:30 d.antipseudomonas drug : a-metronidazole b-nystatin c.immunosuppressant agent cannot used in organ transplantation : Predisolone 203. avoid aspirin containing prepration b-avoid doubling dose from herself c-balanced food with green leaves to avoid thrombosis d-if she pregnant.nicotine c.dopamine b. intermittent claudication. diabetic angiopathy.about cardioglycosidic effect : 207.which of following is least sedative action ? A-Diazepam B-Estazolam C-Triazolam D-Temazepam 214. which is not true a. In acute disorders of the brain perfusion. and in diabetes. gangrene. Raynaud’s disease. causing disorders in the peripheral perfusion.which drug has spasmolytic action? a-Reserpine b-Amphetamine 215-desmopressin used in :nocturnal enuresis 216.pentophylline used for : a-peripheral vasodilator b-Hypertension c-Cough suppressant Indications Pentofylline is indicated in diseases. Acute disorders of the retinal blood supply.lady take chronic warfarin . including ischemic stroke and resultant conditions. according ppm : .206. including shank ulcers. atherosclerotic and inflammatory disorders.in hypodynamic shock treatment we used :a.aspirin 211-acyclovir used to : Herpes simplex 212.a--ve inotropic b-+ve inotropic c-Hypertension dTachycardia e-Bradycardia 207-all factors affect on distribution of drug except : a-Tissue solubility b-Protein binding c-Molecular weight of drug d-Type enzyme response of metabolism 208-all factors affect on renal clearance except : a-Age b-Sex c-Both d-Disease state 209. 217-2 mg \ L solution .ointment used for : a-Carrier of drug b-Emollient c-A&B d-Increase absorption e-Increase distribution 210. monitor INR to avoid DVT e-take care about nasal bleeding 213. a-Zero order b-1st order c-2nd order d-Mixed order e-A +B 223. what is total dose? (2x70x12)=1680 mg 231-( GMP) mean:a-Good Manufacturing practices b-Good Manu factor Product c-General Manufacture Protocol d-General Manufacture Product 232-how many gm of water add to 5% KCL soln to make 180 gm of solution(w\w)? 5gm--------------100 .Which of the following is NOT predinsolone side effect ? a-cataract b-hypoglycemia c-skeletal muscle weakness d-sodium retention e-lowered resistance to infections 224.about nor epinephrine not true :a-increases B. which is not true ? a-Has gram –ve activity b-Less toxicity c-Narrow therapeutic d-Compatible with other drug e-Usually IV .C 222.When concidering drug therapy for hypertention .002 ppm c-0. for 70kg patient.drug infusion rate is 2mg\kg\hr .ceftazidime : 3rd generation 220-about amino glycoside .a-Film coat b-Enteric coat c-Grinding of tablet 227-which of following tricyclic antidepressant is tertiary amine? Amitriptyline 228.PHARMACOKINETIC CONSTANT :.One of following NOT used to cover bitter taste:. infused for 12 hours .antihypertensive used in pregnancy ? Alpha Methyldopa 229-drug used for peptic ulcer ?( Losec) 230. which is true? a-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-b-blockers should be avoided in asthmatic patient e.a-2 ppm b-0.ACEIs are recommended in pregnant women 225-solutions are better than solid dosage form coz: a-Accurate dose b-Easy to handle c-More stable d-Faster action e-B + C 226.P b-vasoconstrictive c-used in cardiogenic shock d-effective orally e-S. IM 221.normal water used for : a-Eye preparption bParentral preparation c-Solution d-Emultion e-External preparation 219.000002 ppm 218. chemical stability b.deltiazem & nifedipine &flocdipine act as .a.tetracycline .hydralzyine 251.lidocaine c-propranolol d. the amount of water is:.when you know the preservative used with antibiotic is not suitable you make:a.pyrogen free b-free from sod. stomach discomfort or pain.Qunidine has similar action to :a-procainamide b.anion exchange 239-The conc. 242-Cyclophosphamide (side effects) Appetite loss. weakness. hair loss.Over dose of digoxin we use:-(anti dote FAB Fragment ). 245-The most common reaction catalysed by cytochrome P450 is a monooxygenase 246-The most common phase I reaction is oxidation 247-Which Of The Following NOT Used In Peptic Ulcer :a-Tetracycline b.use two or more preservative may increase the activity and may become suitable d.All of this affect rate of absorption except:.B&C 237-Alteplase &streptokinase used in:( Pulmonary emboli ) 238-Cholystyramin resin act by :.gamma rays.a.add another to increase it is activity b.Xgm--------------180 X= 5x180/100=9 gm So.lidocaine b-minoxdil c. texture change in nails. 244-Coal tar uses in (psoriasis).PH c-protein binding d. 253.a+c 235. diarrhea.Itraconazole c-Metronidazole d-bismuth subsalicylate e-clarithromycin 248-Which Of The Following act as alpha 1 blocker :.180 .Ampicillin has similar action of:.d-free from bacteria e.Which of the following drug has side effect lupus like syndrome : a. general unwell feeling.hydrazyline b-terazocin c-propranolol d-captopril e. absence of menstrual periods.A&C 250. x-rays. color change in skin. 243-Isoproterenol( Isoprenaline ) adrenergic agonist medication.use another one is suitable b.procainamide d-hydrochlorothiazide 252.block Ca to intracellular & increase metabolism from storage site 236. Of ionized & unionized calculated by (Henderson hasselbachk equation) 240. Chloride c.a.according to sterile method which of the following is false about filteration:able to filtter viscous substance 234.clonidine 249-comparison between sterile water &water for injection:.a. nausea.Light sensitive drug should be storage in:a-Colorless glass b-Colorless plastic c-Amber glass d-Amber plastic e-Light resistant container 241-Electromagnetic rays :.9 =171 gm 233. vomiting. skin rash.A&B e. 4% calculate the amount of drug? a-0. > susp. 0. > solu.(inhibited blood clot ) 265-cyclophosphamide side effect is:a-blurred vision.penicillin V 257-Auxliar of label are written on box contain COTRIMETHOXAZOLE all is true except:a-shake the bottle before use b-suspension c-freezing of drug d-keep out of reach of children 258-Ipratropium bromide :-(Anti muscarinic bronchodilator ) 259-keep in cool place means :a-in refrigerator b-in freezing c-at 10-20 c* d-A&C e-A&B 260-5ml of injection that conc.2mg c-200mg b-2mg d-2000mg e-20mg 261-How need prepare benzacainamide conc.Meropenem b. > oint . c-susp.Cephalosporin act as:a-Inhibitors of cell membrane function b-inhibitors nucleic acid synthesis c-Inhibitors of protein synthesis d-Inhibitors of cell wall synthesis e-Inhibitors of metabolism 255.30cc of benzocainamid solution? A-30 b50 c-80 d-100 e-130 262-Amphetamine act as :(INDIRECT-ACTING ADRENERGIC AGONIST) 263-Increase plasma HDL Level :(Reduce Risk of Atherosclerosis ) 264-Warfarin act as:.Amoxicillin d. Proffered to be taken:.alopecia c-bone marrow depression d-A&B e. >oint d-any dosage form can be used 270-digoxin toxicity precipitated by :. > oint > susp.a-solu.B-cephalexin c-cloramphenicol d-amikacin 254.Antibiotic used as anti pseudomonas aeruginosa:a. b-solu.(Hypokalemia) .…………… b-vomiting . 267-which of the drug used in open angel glaucoma:(pilocarpine ) 268-All (ACEIs) are prodrug except:CAPTOPRIL (prototype) 269-Opthalmic prep. 1:1000.Bacitracin c.B&C 266-Action of alpha 1 receptor:-…………………. 285-Vit.000 IU/day.000 IU for the correction of the deficiency & for therapy from 100.a-hypercalcemia b-Hypoglycemia c-Hypokalaemia d-Hyperuricemia e.PSORIASIS 294-which of the following make water retention:.Serotonin (5HT2a) receptor 283-All these cases not cure with thiazides except:a-hypernatrimia b-Hyperglycemia c-Hypokalaemia d-Hyeruriceamia e-Hyponatrimia 284-Which of the following drug of choice for Myxodema:(Hypothyroidism ) :-Thyroxin sod. To :AUC (Area Under the Curve ) 275-Cephalaexin is :. 288-Bisacodyl used as :.first generation cephalosporin.R c.Hyponatrimia 287-Zidovudine is used for HIV.Aqueous diffusion b-Osmotic pressure c-Lipid dissolve d-Passive diffusion e-NON of the above 293. 286.R b-shorten P.HEPARIN 299-Prmethazine used as :- .Laxative 289-POM mean:.Vit.peptic ulcer 279-Alph 2 Agonist :.Calcipotriol is indicated for :.T.(Ibuprofen ) 272-Digitoxin effect in electrocardiochart (ECG):a-prolong P.Decrease blood pressure 280-The equation that determine the acid & base degree is:(BRONESTED EQUATION) 281-ISONIAZIDE used in TIBERCULOSIS .271-which of the following drug has anti inflammatory effect :.All these cases occur with thiazides except:. 282-mechanism of action of Buspirone on:.R 274-Relative bioequivalent compared between std.WARFARIN 298-protamine sulphate is anti dote of:.R c.Sod. A daily dose is 30. Has 0.000-50. Lauryl Sulphate 292-The drug transfer through the cell membrane by :a. Of the drug on exp.prescription only medicine 290-The con.(Dopaminergic Antagonist) 297.(Vasodilatation of coronary artery).5mg/ml dissolve in 30ml water calculate the amount of KI in the solu. Date is :From 90-110% 291-Surfactant not used orally :.R b-shorten P.T. 276-After the myocardial infraction we use :Anti-platelet (aspirin) 277-KI solu. K is antagonist of :.(Indomethacin) 295-Nitroglycerin is :. drug &test drug acc.R 273-Digitoxin toxicity effect in electro cardio chart (ECG):a-prolong P. ? (15mg) 278-Omeprazol used for :. shaped d-prolong B.000-200. shaped d)prolongB. 296-Anti psychotic act as :. Anti histaminic (pruritus . Of penicillin through :a-increase renal tubular reabsorption b-decreases renal excretion c-decrease hepatic metabolism 308-one of the following not toxic effect of methyl dopa:a-sedation b-drug fever c-gangrene d-anemia e-hepatitis 309-patient take cisplatin should be taken with :Granisetron (anti emetic ) 310-purified water can not used in:a-ophthalmic preparation b-IV solution c-oral preparation d-oral suspension e-A&B 311-ascorbic acid is :-( vit.1mg b-1mg c-10mg d-100mg e-1000mg 306-which of the following is not side effect of propantheline:a-blurred vision b-dry mouth c-constipation d-bronchospasm e-urinary retention 307-probenecid increase the con.The latin abbreviation for<state>:.Inhibit reuptake of catecholamine 313-Isopretrenol is :a-alpha &beta agonist b-alpha blocker c.a-nutrition b-genetic c-mental status d-age e-disease 304-cyclizine used in :a-nausea &vomiting b-antibiotic cbronchodilator d-antihistaminic 305-5ml solu. cough .Which Of The Following act as alpha 1 blocker :. =Y/X 302-ESMOLOl is:Short acting B. gravity of sub. amp has con.(Immediately ) .anti emetic) 300.alpha agonist d-beta agonist e-beta blocker 314-Active immunity can be conferred by :a-anti toxin b-anti sera c-vaccine d-immuno bodies 315-Mechanism of action of echothiophate:( Form stable complex which cholinesterase enzyme ) (Indirect-Acting Cholinergic Agonists ) (Anticholinesterases <irreversible> ) 316.2% amount of drug is :. 303-which of the following has not effect on drug response:. C ) 312-Mecanism of action of Tri cyclic antidepressant:. the sp. 0. =weight (Y) /volume(X)/1 So.a-0. the sp.blocker used in emergency in Acute arrhythmia as IV administration .( PRAZOCIN). 301-Whate The Specific gravity of substance has Weight=Y & The volume is X ? The Specific gravity =Density of the substance/Density of water So. gravity of sub. A)bacteria b)virus c)fungi d) a+c e)b+c 334-Not used clinically:a) heroin b)morphine c)codeine d)oxycodone hydro morphine.) congestive heart failure we use digoxin to:a) incr.( bronchospasm ) 338.22 m filter.Sterility through .myocardiac contraction b) increase myocardium excitability c) dec.In (C. 318-ventmix(Salbutamol) is :.Which increase the action of morphine:a ) vit k b)carbamazepine c)amiodarone d)contraceptive e)none of the above.F.=80ml) 337-side effect of class 2 antiarrhythmic:. do not remove:.(bronchodilator) 319-Diltiazem not used in :a-heart failure b-Angina pectoris c-Hypertention (HTN) d-SA node block e. 332-Tetracaine used for:a) Spinal anesthesia b) opioid analgesic c) neuromuscular blocking agent d) vit d metabolite c) in treatment of Parkinsonism.Which of the following Not occur in digitalis toxicity:. 333.myocardiac contraction d)…………………………………………… 339-The least sedating:a) Diazepam b) chlorodiazepoxide e) probamate f) oxazepam g) buspirone .(fluminzanil) 327-Thephylline side effect is : a-skin rash b-insomnia d-……….How many benzocaine used to prepare 1:1ooo.Headache 320-Drug used in Diarrhea &constipation :a-polycarbophil b-pictin c-senna d-………… 321-Alpha blocker has side effect :.(verapamil) 331-Patient who is allergic to penicillin use:a) claforan b)erythromycin c)cefotetan d)augmentin e)cephalexin. 80 cc benzocaine… ( sol.H.\a)hypokalemia b)hypomagnesia c)hypocalcemia d)hypothyroidism e)impaired kidney function.Volume of blood /mint cleared through kidney called:a-total body clerance b-renal clearance c-hepatic clerance d-………………. 330-class IV anti arrhythmia is :..(postural Hypotension) 322-the dose of cefixime :a-400mg b-800mg c-1200mg d-1500mg 323-the dose of asprin as antiplatelet:a-80mg b-120mg c-250mg d-500mg 324-Alpha calcidiol can not used with patient:a-liver dysfunction b-renal dysfunction 325-co-trimethoxazol precentage of trimethoprim to sulphmethoxazol is : a-1:2 b-1:3 c-1:5 d-1:10 326-diazepam over dose ttt with:.317. 335. 328-Dipivefrine is:a-Anti HTN b-chelating agent c-Glucoma 329. 336. means to be taken 4 times daily.s. 344-Cushing syndrome caused by taking:. 348-Not expected with inhaled smoke of cannabis:a)increase pulse rate b)anorexia c) Perceptual changes d)vascular changes of eye.S.force of contraction e) selective dilate renal & mesenteric 352.Verapamil can increase effect of (theophylline & carbamazepine &digoxin…..N.Glucocorticoid drugs 2-tumor secret high cortisol level…… 345-Q. colestipole.) 353-Used in treatment of Parkinsonism:a)amphetamine b)dopamine c)nicotine d)albuterol 354-Aspartame is used as………sweetener… 355.60% 350-Na Pico sulfate is used for …laxative…. 346-Vit A avoided in:a) Rickets b) blindness c) pregnancy d) scurvy e) a &d 347-Which not effect of theophylline:a)peripheral vasoconstriction b)cardiac stimulation c)dieresis d)relax of stomach muscles e)stimulation of C.Hormone replacement therapy in all postmenopausal women :a)true b)false 356-Properties of catecholamine:a)rapid metabolism by ACHE. 349-Percentage of water acc.B for how long????? 24 months 361. b)slow metabolism by ache c)slow COMT d)not related to COMT and MAO. 357-antihypertensive act as alpha 1 blocker in artery & vein:a)hydralazine b) minoxidil c)terazocin d)…… …… 358-bile acid sequestrants: cholestyramine. d) scurvy e) a& d.340-drug not decreases LDL:a)simvastatin b) clobifibrate c) nicotinamide d)propecol 341-RALOXIFINE IS SELECTIVE ESTROGEN MODULATOR CONTRAINDICATED IN DVT PATIENT:.O. To body weight is…. sevmesol 359-ACEIs & ARBs r contra indicated in :renal artery stenosis patient 360-cycloserine used in T.natural water can be used in :.d.external preparation 362-ideal volume of eye solution:a)500micro b)50-250 micro c)10-50 micro d)<10 micro . c) Don't induce preiphral vasoconistriction d) dec. 351-Dopamine is used in cardiac shock as:a) increase lung performance b) decrease C. ) myocardial infraction:a)albumin b)signs and symptoms c)troponin.I.1..( true) 342-Promethazine is used for:.P.(antihistamic) 343-Which of the following Not used in diagnosis of acute (M. A-tachycardia b-bradycardia c-……………… 368-propranolol is:.clofibrate act as :1-decreas HDL 2-deacreas lipoprotein lipase 3-synthesis of cholesterol 4-decreases lipoprotein 376-water used for reconstitution of large dose of parentral is:.water for injection b-distal water 377-all of the following side effect of hydrocortisone except:a-Na retention b.(none selective b-blocker) 369-which of the following drug cause tachycardia:a-propranolol b-atenolol C-hydralazine d-…………… 370-enkefaline as peptide used in :a-electrical conduction as neuron transmitter b-similar in action to morphine -…………………………………… d 371-the dose of drug is 0.osteoporosis 378-reserpine side effect: a-parkinsonism b-depression c-……………….epinephrine analogue used in glaucoma 364-idoxrubicin is:.antiviral for herpes simplex 365-when pharmacy owner give direction to employee in his pharmacy to monitor policies& regulation it is : -a)danocratic b) democratic c) participation d)consultative 366-ALL OF THE FOLLOWING ACTION OF CAFFAINE EXCEPT:A-CNS STIMULANT C-DIURETICS B-SKELETAL MUSCELE RELAXANT D-CARDIAC STIMULANT 367-NITRO GLYCRIN SIDE EFFECT is:.5ml per day and the total amount of the drug Is 100ml what is the total dose ?sol.363-dipivefrine is:.glucose tolerance c-arthritis d. 374-the main site of execretion of the drug in the body is:A-kidney b-liver C-stomach 375.= <200 > 372-drug dose is 5 present in 1ml & we give 5dose of one tea spoonful What is the concentration by micog? 5--------------1ml 25------------? =5ml = 5000 microgram 373-pentoxifylline use as :a-peripheral vasoconstriction b dry cough c-………………….a-sterile water for for injection b. 379.pH use to : . .BIO AVILABILITY MEAN THE DRUG REACH: A-SITE OF ACTION B.BLOOD CIRCULATION c-………………………….Diloxamide c-Sodium Stibogluconate d-Emetin 386-All of the following preparations contain alcohol except:a-Syrup simplex b-Aromatic ammonia spirit USP c-Terpin hydrate elixir USP d-Belladona tincture B.and c .P 387-Wich of the following solutions is used as an astringent? a-Strong iodine soluotin USP b-Aluminium acetate topical solution USP c.Which of the following drugs is a systemic amoebicide? a-Diloxamide furoate b.Acetic acid NF 388-an extrapyramidal adverse effects is caused by the blocking of:a-Serotonin receptors in the brain b.Enzyme CYT P450 discovered by :381.Acetylcholine receptors in the brain c.a-determine acidity b.Amantadine c-Ribavarin d-Vidarabine 385-Which of the following drugs is used in the treatment of Leishmaniasis? a-Pyrimethamine b.Pyrimethamine c-Emetin d-Sodium Stibogluconate 383-Which of following drugs is the drug of choice for the treatment of all forms of Schistosomiasis? a-Praziquantel b-Mebendazole cNiclosamide dThiabendazole 384-Which of the following drugs can be used for the treatment of influenza A infection ? a-Zidovudine(AZT) b.increase with basic c for POH 380. Dopamine receptors in the brain d-Dopamine receptors outside the brain 389-A rare side effect of some anticonvulsants is StevensJohnson syndrome.b. 382. this is a severe:a-Skin reaction b-Bone marrow toxicity cRenal failure d-CNS suppression 390-Which of the following are side effects of phenytoin treatment? a-Acne b-Hirsuitism cGingival hyperplasia d-a. A&B e.Rate of blood flow to tissue c.Cytabrin e-Cyclophosphamide 398-All These drugs can be used for Parkinsonism except : a.optic neuritis c.391-all factors affect on distribution of drug except :a-partition co-efficient b.Anticoagulant b.Nedocromil Sod.peripheral neuritis d.Flurouracil C.PH d.Pergolide d.Selgitine HCL b.Steptokinase c.Methotrexate b.iron deficiency anemia 395-Ticlopidine is used for :a.NONE 397-All These drugs cause anti-metabolic effect except :a.Propranolol d.Regular type b.Antibiotic c.30/70 type .Antiplatelet 396-All these drugs are fibrinolytic except :a.anticholinergic d. is :a.Irreversible a plastic anemia b.Ephedrine bLidocaine d.Dipyridamole b.urikinase d.Normal saline 400-Insulin which can be given I. 399-Cardiac arrest could be managed by the following except :a.B&C 392-Which of the following is NOT betamethasone side effect ? a-hypoglycemia b-skeletal muscle weakness c-sodium retention d-lowered resistance to infections 393-Which of the following are causes of oedema? a-increase hydrostatic pressure b-decrease oncotic pressure c-increase capillary permeability d-all of the above 394-All These are side effects of Chloramphenicol except:a.Carbidopa c.V. A 404-One of the following is not from Quinolone group :a.Respiratory depression c.Sod. c.Lomefloxacin c. Cromoglycate d.c.Treatment of migraine cAngina Pectoris d.Constipation d.Non of the above 402-All These are natural Estrogens except :a.Vit.Zalcitabine b.Norfloxacin 405-One of the following is not for Epilepsy :a.Salbutamol 408-All of the following is NSAH [ non sedating antihistamine ] except :a.Clorizepam b.Rivotril b.Primidone d.Ketotifen b.Hypertension b.urikinase d.Azotodin 409-All of the following are controlled drugs except : a.Cetrizine c.Nedocromil Sod.Sresolid d.Oestradiol 403-Which one of the following has vasodilator effect :a.Naprox bb.Quinine c.Nicotine b.Oestrone cOestriol d.Cholestyramine c.Epanutn c.Vomiting 411-Which one of these drugs is not used for acute pain :a.Colchicin .NPH type d.Phenytoin c.Non of the above 401-All These drugs are anti-bacterial except :a.Loratidine b.Eoxacin d.Diazepam 410-Which one of the symptoms does not occur with morphine : a.Imipramine 406-Sumatriptan is used for :a.Cefprazone d.Diarrhea b.Astemizol d.Mestronol b.Nalidixic acid b.Control of Epilepsy 407-All of the following for prophylaxis of asthma except :a. Regular Insulin ne cCodeine 414-Dobutamine is given I. generation Cephalosporin c.2nd.Hypokalamia d.Neutral insulin d. M U Khan .It is needed in large quantities in case of oral route c.Three times / Year d-None of the above 413-One of the following is given once daily:a.Not affect K [ Potassium ] 416-Cefaclor is : a.Gentamycin b.Tobramycin Prepared by D. because :a.Ist.Prednisolone 412-Hepatitis Vaccine dose is : a.None of the above 417-Which Aminoglycoside antibiotic can be taken orally ? a.Once / year b.Twice / Year c.Amorphous Insulin b. Generation Cephalosporin b. generation Cephalosporin d.3rd.None of the above 415-Amiloride as trimetren causes :a.CNS disturbances b.Protamine Zinc Insulin c.Neomycin c-Amikacin d.Hyperkalamia c.It is eliminated very quickly d.It is not stable in the gastric PH b.V.d. . which of the following is parenteral rout of administration: subcutaneous IM IV All of the above 5.which of the following drugs not used in Acute pain: Morphine Phentanyl Naloxone Dexamethasone 4.If the Prescription is not clear: Return it to the Doctor Give it to the Pharmacist Dispense the clear drugs Return it to The patient 3.Which of the following β blocker used in ophthalmic preparation? Timolol Propranolol Labetalol Pindolol 7.Insulin Storage at: 0c 4-8 c 24 c 25 c 6.Prescription Must contain all of the following Except : name of the patient Diagnosis Single or Married Dosage form 2.1.Fluoxetine belong to: Proton pump inhibitor ACEI . Treatment of Hypertension in pregnant woman: Captopril Verapamil Methyl dopa All above 9. Dose of Klacid (Clarithromycin): three times per day Twice per day once four times per day 9.trade name of Fosinopril is: Capoten Reinetic Zestril Monopril 12.Atenolol is : alpha blocker non selective betablocker Selective beta 1 blocker beta agonist 11.Atenolol sold in KSA under trade name of: Indral Tenormin Capoten Zovirax 10.Selective Serotonin reuptake inhibitor Oral hypoglycemic 8.Heparin is: Antiplattlet Anticoagulant . Which of the following drugs are not OTC: Aspirin Bisacodyl Tegretol Malox 15.Generic name of Zantac: Ranitidine Cimitidine Famotodine Nizatidine 17.Fibrinolytic Analgesic 13.over dose of panadol can be treated with: Naloxone EDTA Vitamin K Acetyl Cysteine . Advantage of Salbutamol over other bronchodilator: Long acting More potent Low side effect Fast Acting 14.Diltiazim is: beta blocker Ca channel blocker Na channel blocker Alpha blocker 18.Side effect of oral Hypoglycemia: Hyperglycemia Hypoglycemia Hypernatremia Hypertension 16. bid means: three times per day two times per day four times per day once daily 22. all of these drugs are controlled drugs except: Morphine Nalbuphine Aspirin Methadone 25.qid means: three times per day two times per day four times per day once daily 21.Opoid toxicity can be treated with: .qod means: three times daily every day four times daily Every other day 20.about Tetracycline all of the following are right except: It can suppress the growth of bacteria It binds to bacterial Ribosome Active against G+ve and G-ve Safe for children use without affecting color of teeth 24.tid means : Three times per day two times per day four times per day once daily 23.19. Dapson is : Beta lactam Antibiotic Cephalosporines Sulpha drug Antacid 27.3 % 0.Rheumatoid can be treatment with: Gold derivatives drugs Platinum derivatives drugs Silver derivatives drugs Non of the above 28.which of the following dosage form can be administrated orally: Spray Suppositories Ointment Elixir 30.9 % 90 % 29.which of the following drugs inhibit liver enzymes: Paracetamol Epanutine (phenytoin) Cimetidine .Paracetamol Naloxone Deferroxamin Vitamin K 26.Aspirin used as: Analgesic Antipyretic Antinflammatory All above 31.Concentration of normal saline: 9% 5. Maximum dose of Diclofenac ( Voltaren): 1000 mg/ day 200 mg/day 4000 mg/day 3200 mg/day 38.Side effect of Atropine: Diarrhea Headache Dry mouth Constipation 35.Acyclovair 34.Side effect of Buscopan: Diarrhea Headache Dry mouth Constipation 39.Rifampicin b.Which of the following drugs Induce liver enzymes: a.Rantidine c. Amphotericin is: Antibiotic Antifungal Antiviral Antiprotozoal 36.Aspirin 33. Metformin used as: Antibiotic Antihypertensive Oral hypoglycemic . Vasopressin used in treatment of: Diabetes mellitus Diabetes Insipidus Hyperthyrodism Hypothyrodism 37.Cimitidine d. Zinnat is: First generation cephalosporin's Quinolon Aminoglycosides Second generation cephalosporins 44. Pseudomembranous colitis treated with: omeprazole Mebindazol metronidazole Amoxil The disease is treated either with oral vancomycin or with intravenous metronidazole 41.Amoxicillin + clavulinic present in: Ciprobay Augmentin Zantac Klacid .the Latin abbreviation for four times: qid bid tid qd 43.which of the following is not beta Agonist: Salbutamol Salmetrol Pindolol Albutrol 45.IM administration Site of Injection: Arm Restus Lateral (lateral restus in the eye) Buttocks All of the above 42.Antianginal 40. Which of the following effect is not considered in formation of suspension: use of chelating agent of whiting agent particle size non of the above 49.Quality control is control of: condition specification shelf life all above 48.Analgesic indicated for Asthmatic patient: Paracetamol Aspirin Brufen Salbutamol 50.Warfarin over dose can be treated with: vitamin A Acetyl custiene Protamin sulphate Vitamin K 47.46. Streptokinase is indicated for: Pulmonary embolism Impaired fat absorption Tuberculosis Neoplastic anemia 49.Atenolol belongs to: .Antibiotic safe for Pregnant woman: Ciprofloxacin Gentamycin Amoxicillin Tetracycline 51. 5-8.NSAID AB β blocker ACEI 52.Neostigmine should stopped before Pregnancy by: two weeks two months two Years non above 57.content of patient file is: -name+ age+ gender+ diagnosis+ medication -name + diagnosis medication only -name+ age+ gender+ telephone 54.Tegretol b.5-5.Which of the following OTC: a.Celebrex (Celecoxib = NSAID) c.0 (mEq/L)).5-5 (3. 5.Diclofenac taken: Before meal After meal Within meal Not affected by food content 56.Augmentine .Normal Potassium level in blood: 50-30 150-130 3.Used in treatment of AIDS: Acyclovir Rifampicin Zidovudine Prednisolone 55.5 53. Gentamycin c.Cinnarazine cVerapamil d.Phenobarbita l e.Kanamycin dVancomycin 60.Amlodipine b.Minocycline bDemeclocline c.Antiviral d.Which of the following are used in treatment of Hypertension? a.Neomycin 59-.Gentamyc n bAmikacin cTobramycin d.Which of the following are oral amino glycosides a.Folic acid bAmoxil c.non above 58-.d.ACEI bAntibiotic c.Which of the following is not Tetracycline? a.Spironolactone is: a.Similar to Teicoplanin in the effect on G+ve bacteria: a.Amantadin 63.Diltiazem 62.Jamica b.Which of the following Antihypertensive are safe during Pregnancy: .Doxeycline 61.Diuretics 64.Which of the following are not Ca channel blockers? a.Inderal d.Dilitiazem d. Antidote for INH: a.from 2 year to 2 year 69.OTC means: aOver the content b.Vitamin K d.Used in treatment of Amoebia giardia: a.a.Ranitidine b.Scientific name of vitamin B1: Riboflavin Tochopherol Thiamine Pyridoxine 67.Deferroxamin bProtamin c.Ophthalmic Drugs 70.from 6 months to 9 months b.Methyldopa d.yomesan b.Which of the following is contraindicated in Asthmatic patient: a.Capoten 65.Aspirin c.Naloxone b.Over the counter Drugs c.Protamin .Mg sulphate 66.Amlodipine c.from 1 year to 1 year d.Flagyl cPrazaquantil d.Heparin 71.Salbutamol 68.Atrovent d.from 6 weak to 9 weak c.Nifidepine b.Antidote for Warfarin: a.On the counter d.Period (duration) of treatment of Tuberculosis (TB): a. Glucose+ NaCl+ Na citrate+ K citrate c.Imipramine bFluoxetine c.Generic name of Prozac: a.Naloxone 74.20 C b.Glucose+ fructose+ NaCl+ KCl+ Na citrate+ K citrate (Glucose + NaCl + KCl + Na-citrate or bicarbonate) 76.Ramipril b.Sertraline 75.NaCl+ Na lactate+ K citrate b.Generic name of Capoten: a.Vitamin K 72.2.Antidote for Heparin: aDeferroxamin b.Protamine sulphate cVitamin K d.Lisinopril d.sulphate c.Captopril c.Content of ORS: a.15.NaCl+ Na lactate+ K citrate+ MgOH d.0 – 5 C d.4 C .Citalopram d.Propranolol 73.Ideal Temperature for Insulin storage: a.Vitamin B6 d.2 – 8 C c. Normal Hemoglobin level in blood: a.12 – 15 d.pugs bMosquito c.Theophylline is: aBronchodilator b.Nesseria d.Acyclovir used in treatment of: a.5.Fungus 82.5 c.All of the above 79.In male 15-20 in woman 25-30 b.In male 10-12 in woman 8 – 10 80.Fungal infection 83.Viral infection c.bacterial infection b.Anticholinergi cd.Prescription contains Prednisolone as: .5 in woman 12.Malaria Transmitted via: a.In male 13.Antidote for Iron: aDeferroxamin bProtamin cVitamin K dNaloxone 81.β2 agonist c.78.15.Bacteria d.516. 1 X Tid X 3days 1 X Bid X 3days 1 X Qd X 3days How many tablets will you give to the patient: a.9 b.Clindamycin b.All above 87. c.at Rome temp.Use of Barium sulphate: .Vaccines Storage: a.27 d.Away from light b.Prazaquantil c.IV c.18 ? 84.The way that you deliver 100% of the drug to the blood (highest Bioavailability) and rapid action: a.Inhalation 88.Used in treatment of Ascariasis: a.Mebendazole 86.Metronidazole d.at refrigerator d.40 mg / day c.2400 mg / day d.4 gm / day b.Scientific name of Vitamin C: Acetyl Salycilic acid Ascorbic Acid Cyanocobalamine Nicotenic Acid 85.Rectally d.Maximum dose of Paracetamol: a.36 c.3 tab / day 89.IM b. Maltose cFructose d.Sucrose 91Maximum dose of captopril: a.H2 antagonist d.Type II diabetes use: a.Red Man Syndrome is the side effect of: a.125 mg/day b150 mg/ day c.oral hypoglycemic b- .for Conistipation cRadio contrast agent d.for Diarrhea 90Salivation Enzyme converts food into: aGlucose b.Three tab / day (450mg/day) 25-125mg bid or tid d.Gentamycin 95.Vancomycin d.Type I diabetes use: a.for Acne b.Glucose 94.Antidote 93.4 gm / day 92-to avoid more absorption of toxic drugs use: a.a.Aspirin bMetronidazole c.Insulin bSulphonyl urea c.saline bCharcoal cAntibiotic d. Gentamycin 98.Paracetamol bMetronidazole c.Dextrose sol d.Insulin c.Acetyl salisylic acid d.Paracetamol bMetronidazole c.Indomethacin 100Ondansteron HCl is used for: a-hypertension b-angina pectoris c-prophylaxis of migraine d-anti-emetic 101All of these are side effect of Chloramephenicol except: a-irreversible aplastic anaemia b-optic neuritis cperipheral neuritis d-iron deficiency anemia .sulphonyl urea 96Which is contraindicated during pregnancy? a.Vancomycin d.Gentamycin 99.Ciprofloxacin dPenicillin 97Nephrotoxicity is the side effect of: a.Diclofenac Sodium bPiroxicam c.Hepatotoxicity is the side effect of: a.Generic name of Voltaren: a.Methyldopa bParacetamol c.Vancomycin d. Mg d.Fosamax is the trade name of: a.Flagyl c.constipation 109The antacid that cause diarrhea is: a.Clindamycin 106.antiviral cantiprotozoal d.Ca b.Sporanox is used to treat: (itraconazole) a.Famciclovir bZidovudine c.Acyclovir d.antibiotic 107.Amantadine 105.Dapsone d.all of the above .Dapsone b.antifungal b.Amantadine cAlendronate (bisphosphonate) d -Warfarin 108Bisphosphonate is used to treat: a.Al c.Acne b.Pseudomembraneous colitis is the side effect of: a.Vancomycin b.Osteoporosis cContraceptive d.102Ticlopidine is used for: aanticoagulant b-antibiotic canticholinergic d-antiplatelet 103Teicoplanin is used for: aanticoagulant b-antibiotic canticholinergic d-antiplatelets 104Retrovir is the brand name of: a. Amoebiasis c.6 weeks d.Respiratory depression cCardiac Arrest d.N-acetylcystine c.6 months 115SNF is: a. 114The duration for treatment of Brucellosis is: a.Liver dysfunction 113.Ascaris d.Taenia 111Amenorrhea is defined as: a.Which of the following is INCORRECT? a.Impotence d. the recommended antidote is: a.IV normal saline b.Elixir is a solution that contains alcohol as diluent.A syrup is an aqueous solution that has a sweet taste.110Sodium Stibogluconate is used to treat: aLeshmaniasis b.Epinephrine .2 months c.painful menstruation b. diseases and other scientific materials 116.Sustained release tablets should be crushed before dissolving when given to a patient.What is the major complication of morphine overdose? a – AV-Block b. dRegular tablet is a solid dosage form.Saudi National Formulary d.Absence of menstruation 112.2 weeks b.Southern Non-fatal Fever bSinusitis Nasal Formula c.In case of acetaminophen poisoning. c.Premenstrual syndrome c.Computer software contains information about drugs. b. Augmantin b.None of the above 121Intraosseus injection (IO) refers to injection into the: a.Amitriptyline c.Dapson c.d.Bone marrow b.Comazol d.50 mg every 6 hours b.Ultracef c.Muscle mass d. that means: a.H2 antagonists b.Bactrim b.Lidocaine 118.It is absolutely contraindicated during pregnancy b.A and B d.A patient complaining of changing of his urine color to red/orange.Superficial skin layer c.Absolutely safe d.None of the above 123The recommended dose of Paracetamol for a 10 kilogram child is: a. Which one of the following drugs might cause it? a.Activated charcoal 117.Pleural fluid 122The generic name of Cotrimozazole is: a.Rifampicin d.Procainamide b.Diphenyhydramine 119.Can be used with caution c.Can be used in the third trimester only 120Sedating antihistamines effect is related to: a.150-300 mg four times daily .Propranolol d.Which one of these drugs is NOT an antiarrhythmic agent? a.H1 antagonists c.Misoprostol is classified by FDA as pregnancy category X. c.Phenytoin b.Insulin 128Quinolones are NOT recommended in children because: a.Insulin 127Which of the following drugs should not be mixed with dextrose for intravenous administration a.They are not very effective unlike the adults b.240 ml (1US fluid ounce =29.15 mg every 4-6 hours d. The study of the biochemical and physiological effects of the drug.5735) b.none of the above 126Which of the following drugs should not be mixed with normal saline for intravenous administration a.Amphotericin B d.Amphotericin B d.Phenytoin bCefazolin b. dosage form. and side effects of the drugs.100-150 mg every 4-6 hours 124.120 ml c.Pharmacodynamics is defined as: a. b.Drug interactions.7 b.all of the above.60 ml d.Cefazolin b.5 125.5 – 8. d.Eight fluid ounce equal to: a.Which of the following medications cause Rhabdomyolysis? a.Less than 7 c.The have serious side effects on liver c.Sumatriptan cPhenytoin d.The pH for acidic preparation is: a. cThe study of time course of a drug and its metabolite in the body after administration.They may affect their joints d.Simvastatin b.They make the child hyperactive 129.Fusidic acid injection 130. .More than 7 b.5. Vasoconstriction and increasing systemic blood pressure and coronary blood flow. dLamivudine.The drug of choice for head lice is: a. b.None of the above. c.Antihistamines.131A father seeks your advice for his 2 months old child complaining of runny nose and Temperature of 39°C. 132Upper respiratory tract infections are treated sometimes with antibiotics. For HIV 136Norepinephrine stimulates β1 adrenergic receptors and α adrenergic receptors causing: a. 135All of the following consider Calcium channel blockers EXCEPT: a.Give him paracetamol and Actifed.Virus.increased contractility and heart rate. (Pyrethroids) & Malathion c. d. b. The comments microorganisms for which you suggest an antibiotic are: a. b.Protozoa 134. b. c. 133Histoplasmosis is caused by an internal invasion of the body by: a.Diltiazem.Watch the child for the next 48 hours. d.Helminthes d. cMixed micro organisms.Gram negative organisms.Fungal infection c.These drugs cannot be . potent nucleoside analog reverse transcriptase inhibitor (nRTI). 137.Start him immediately on Amoxil.Pyrithrins.Take the child to the emergency department. What is your advice? a. b. c. dAntibiotics.Felodipine.Topical steroids. b.Gram positive organisms.A and B dNone of the above.Nifedipine. 139Which of the following are secreted from the pancreas? a. 142How much magnesium sulfate is in 10 ml of a 200 mg/ml magnesium sulfate solution a.Insulin Lispro. c-hypokalaemia. cPravastatin.Formation of complexes in the GI tract cause irritation. d. so he receives………. d-hyperuricaemia. 140The insulin that cannot be given intravenously is: a. d. dMetformin.Insulin only. bTegretol. b.Insulin + FSH. d.The well known complexion reaction between Warfarin and certain drugs containing metal ions such as aluminum hydroxide leads to: aFormation of complexes in the GI tract that is poorly absorbed.2 gm (2000mg) c.1000 gm d.dispensed to patients without a prescription EXCEPT: aBisacodyl.1 gm b.mg/day .840 mls d. c.280 mls b560 mls c. 138. b. bhyperglycemia.NPH.A 20-kg child receives erythromycin 30 mg/kg q6h..all of the above.Insulin + Bile acids. c.Regular. bFormation of complexes in the GI tract that is highly absorbed. 141All these cases not cure with thiazides except: a-hypernatremia.None of the above 144.2000 gm 143How many milliliters of ampicillin do you have to dispense if the patient needs to take 2 tsp qid for 7 days: a. c.None of the above.Insulin + Glucagon. None of the above 146.66 b) 77 c) 13 d)-3.three grains equal………mg a.a.8)+32 148. -solution containing 10 mg dextrose in 100 ml water -solution containing 10 mg dextrose in 100 L water -solution containing 10 gm dextrose in 1000 ml water -solution containing 10 gm dextrose in 100 ml water 149 0.3600 c.23 .65 c.168 b.minims a)14.milligram sodium chloride in 30 ml.180 b.25 Dihydroxycholecalciferol 1 Dihydroxycholecalciferol 25 Dihydroxycholecalciferol None of the above 147 25 oC = …….2400 d.120 145. oF a)31..D10W means…………….195 d.27 b) 270 c) 135 d) 0.8 F=(oC1.135 150 1 milliliter =……. a)0.5 NS solution contains……….Calcitriol is: 1. if the patient takes 900 ml at the morning and 600 ml in the evening.23 d) None of the above 151 1deciliter = ………liter a)10 b)100 152. How much drug will the patient take in 15 days? 15 mg 15 gm 225 mg 225 gm 153.5 L 5L 50 L None of the above 154-When the patient want to take Viagra.23 c) 16.The concentration of one drug is 1:100.How many milliliters of a NS solution can be made from 4500 mg of sodium chloride? 0. you should ask him: If he is asthmatic His age If he is taking nitroglycerine All of the above 155-How many grams of water needed to prepare 150 gm of potassium acetate solution with concentration 4% w/w? 157 6 156-What is the concentration of solution. if we dilute 100 ml 5% of antiseptic solution to 200 ml? 10% .b) 15. esmolol b.ephedrine d.Which one of the following ß blockers used in ophthalmic drops for treatment glaucoma a.phenylephrine .metoprolol 162.clonidine d. so the patient receives………….esmolol bpropranolol cTimolol d.metoprolol 160.acetylcholine b.5% (n1v1=n2v2 formula) 157-A patient who weighs 50 kg receives 5 mg/kg of acyclovir tid.epinephrine c.Which one of the following ß blockers used as antiarrythmia as it can block K (potassium) channel a.Which one of the following is considered non selective ß blocker a.esmolol b.timolol d.amphetamine 159.propranolol d.Which one of is used as ß2 agonist? a.betaxolol c.5% 2.butoxamine c.mg/day 15 250 500 750 158-The main neurochemical transmitter in the parasympathetic nervous system is a.salbutamol b.sotalol 161.sotalol c.5% 0. The trade name of prazocin is: a.methylergonovine (Methylergometrine) d.ergotamine b.Minipress b.Methysergide 167.Which one of the following used as vasodilator and can be used in benign prostatic hypertrophy? a.Which one of the following agents used to decrease postpartum hemorrhage? a.Which one of the following agents can be used in migraine prophylaxis? a.methsyrgide 168.ergonovine c.methylergonovine d.ergotamine bergonovine cmethylergonovine d.ergonovine c.163-isoproterenol is sympathetic agonist and can be used by: a.ergotamine b.methsyrgide .Which one of the following agents used for migraine treatment (acute attack)? a.Flagicure cCanesten d.injection binhalation ctopically drectally 164.ergonovine (ergometrine) cmethylergonovine (methylergometrine) d.Which one of the following agents can be used as powerful oxytocic? a.Zodium 166.tolazocin bprazocin cphentolamine phenoxybenzamine 165.methsyrgide 169.ergotamine b. nifurtimox 176.Vitamin k verapamil 171Which one of the following parasympathomimetic can be used as antiemetic? a.170The anticoagulant effect of warfarin decreased by the use of: a-Rifampicin b.protozoa infection 175.viral infection bbacterial infection cfungal infection dprotozoa infection 174.flubendazole calpendazole d.Which one of the following parasympathetic agent can be used as ophthalmic drops to treat glaucoma? a.pilocrapine c.Aspirin c.carbachol b.pilocrapine bbethanecol cmetoclopramide edrophonium .Which one of the following can be used in treatment the toxicity of organophosphorus compound? a.ecothiopate bpyridostigmine cparathione d.viral infection bbacterial infection cfungal infection d.bethanecol d.Parlidoxime 173.histoplasmosis is considered a.amebiasis or amoebic dysentery can be treated by a.candidiasis is considered a.metronidazole b.Metoclopramide 172. diarrhea c.The H1 blocker is used as: a.loratidine bastemizole cdiphenhydramine d.Which one of the following is considered sedating antihistaminic? a.rapid pulse 178.diphenhydramine d.Pirafen® 181.Claritin® is a trade name of a drug and the generic name is? a.acrivastine 179.The H2 blocker is used as: a.ulcer cantidiarrhea d.antiallergic b.loratidine b.Which one of the following used for treatment peptic and cd- .acrivastine 180.Trictine® b.Telfast® cAllergex® d.antiamobeic 182.177.dry mouth d.constipation b.All of the following are atropine side effects except: a.fexofenadine is antiallergic and can be sold under the name: a.astemizole c.Ulcer antidiarrheal antiamobeic 183.antiallergic b. Anafranil® 185.acrivastine 184.duodenal ulcer? aastemizole bcimetidine c.as benzodiazepine is less liable to produce tolerance cbarbiturate is more liable to produce tolerance d.amobarbital d.Phenobarbital cd- .The trade name of cimetidine is: a.amobarbital d.thiopental b.phenobarbaital 188Which one of the following is considered short acting barbiturate? a.Histac® b.amobarbital d.all of the above 187Which one of the following is considered ultrashort acting barbiturate? a.secobarbital c.Histac® b.secobarbital c.thiopental b.Zantac® cTagamet® d.as benzodiazepine is more safer b.Which one of the following is considered long acting barbiturate? a.secobarbital amobarbital phenobarbaital 189Which one of the following is considered intermediate acting barbiturate? a.thiopental b.The trade of ranitidine is KSA is: a.phenobarbaital 190.Zantac® cTagamet® d.secobarbital c.Anafranil® 186Benzodiazepine is preferred as sedative hypnotic than barbiturate: a.thiopental b.ticlopidine d. 191.naloxone c.chloroazepam calprazolam d.diazepam b.Which one of the following can be used in morphine overdose? a.alfentanyl 197.isoniazide plus streptomycin b.disulfiram b.buspirone flumazenil parlidoxime 195Which one of the following can be as anxiolytic drug? a.Death can occur in morphine toxicity due to: a.parlidoxime 194Which one of the following can be used for treatment alcohol addiction? a.methadone b.Hypotension b.disulfiram b.buspirone c.parlidoxime 196.rigfampin and streptomycin d.pethidine d.buspirone c.rifampin and ethambutol 192-Xanax® is sedative drugs and the generic name is: a.flumazenil d.disulfiram b.clorazepate 193-which one of the following can be for treatment benzodiazepine overdose: a.Leprosy can be treted by a.flumazenil d.Respiratory failure cCardiac arrest cd- .dapsone and clofazimine c. All of the following are considered selective serotonin reuptake inhibitor (SSRIs) except: a-Fluoxetine b.ethambutol & clofazimine 202.cephalosporin d.The death occur in cholera due to a. rifampin .Meningitis 198.All of the following can be used as antitussive except: a.codeine b.ethambutol & pyrazinamide bisoniazide.Cholera can be treated by a.Clozapine b.Respiredone cLithium d.B is abbreviation for tuberculosis which can be treated by a. rifampin.none of the above 200.The active ingredient in Leponex® is: a. rifampin .dextromethorphane cmetronidazole d.isoniazide.Citalopram c.ethambutol & dapsone d.phlocodiene 199.Sertraline cd- .isoniazide.T.Flagyl® is a trade name of: a.ethambutol & chloramephenicol cisoniazide.Cardiac arrest cDehydration none of the above 201. rifampin .Doxycycline (Doxycycline is recommended as first-line treatment for adults) b.d.Haldol 204.penicillin c.respiratory failure b.alpendazole d.metronidazole bflubendazole c.nifurtimox 203. Imipramine (TCA) 205.phenytoin is generic name of: a.Bional® b.Epiran® d.Tegretol® 208.Sinemet® b.Cidoquin® cDusputaline® d.Epanutin® b.Stellazil® c.diazepam bvalproic acid cphenytoin d.Stroka® 207.Status epilepticus best treated by: a.Primidone 209.Stellazine® Trifluoperazine d.Parkinsonism can be treated by all of the following except: a.partial status 210.Taural® c.L-dopa bDopamine camantadine d.d.grand mal epilepsy c.Idiavix® cd- .carbamazepine is anti epilepsy drug sold under the trade name: a.status epilepticus d.ethusoxamide can be used for treatment of: a.petit mal epilepsy b.Bromocriptine 206-which one of the following is used for treatment Parkinsonism? a. amantadine cganciclovir d.Inhalation all of the above 213Avian flu (Bird flu) can be treated by: a.211.Oestradiol 217Which of the following has vasodilator effect? a-nicotine bcholestyramine c-urokinase d-vit.Oestriol d.zalcitabine b.vancomycin plus metronidazole bvancomycin plus tetracycline c.zidovidine b. Fusidic acid.ampicillin plus metronidazole e. A cd- .Oseltamivir 214-All these drugs are antibacterial except: a.Oestrone c.amoxacyillin plus metronidazole 212Gonorrhea is infectious disease and can be transmitted a. Cefaclor.Nalidixic acid 215-Which of the following antibiotics can be used topically? Acyclovir.Pseudomembranous colitis can be treated by a.lomefloxacin ccefopyrazone d. 216-All these are natural Estrogens except: a-Mestronol b. Cephalexin.sexually btopically c. All of these can be used for leprosy except: a-dapson brifampicin cclofazinine d.One of the following is not for epilepsy: aclorizepam bphenytoin cprimidone d-imipramine 220.INH 221Sumatriptan is used for: a-hypertension btreatment of migraine c-angina pectoris d-control of epilepsy 222Which is enzyme inducer? a-rifampicin bcimetidin c-vit. C d-chloramephenicol 223All of the following for prophylaxis of asthma except: a.218One of the following is not from Quinolone group: a-naldixic acid bquinine c-eoxacin d-norfloxacin 219. c.Ketotifen b-nedocromil sod.Sodium cromoglycate d-salbutamol cd- . zidovudine c.000 IU d.000 IU b. except: a.sresolid d.Cetrizine cAstimazole Azotodin 225Herpes simplex can be treated by a.Loratadine b.30.oseltamivir 226.000 IU cd- .ganciclovir b.000 IU c20.aluerin (antispasmodic) 227Which one of these symptoms not occur with morphine ? a-diarrhea b-respiratory depression cconstipation d-vomiting 228Which one of these drugs not used for acute pain ? a-naproxen b-colchicine c-codeine d-prednisolone 229The Recommended daily dose of Vitamin A for correction of deficiency is: a-5.amantadine b.diazepam 226.zalcitabine d.acyclovir c.10.All of the following are controlled drugs except: a.All these drugs are anti-viral except: a.acyclovir d.rivotril bepanutin c.224All of the following is Non Sedating AntiHistamine. once/year btwice/year c.000 IU 231.One of the following is given once daily: a-Amorphous insulin b.000 IU d.Neutral insulin d.Amoxicillin 233.000 IU c.All these are anti-platelets except: a-dipyridamol baspirin cstreptokinase dticlopidine cd- .Hepatitis vaccine dose is: a.000 IU b.four times/year 232.Regular insulin c.20.All these are anticoagulants except: a-warfarin b-ancord cheparin d.100.230The daily dose of Vitamin A for therapy is: a10.Which one is OTC drug? a-Simple analgesic bWarfarin cCiprofloxacin d.Dipyridamol 235.Protamine zinc insulin 234.three times/year d.50. liver cboth d.Ferrograde is: a-ferrous sulphate bferrous citrate cferrous gluconate d.Amikacin® 237.Acyclovir is a generic name sold in KSA under the name a.none of them 241What is the most drug that can cause damage if it is given OTC? a-captopril b-warfarin c-chlorothiazide drifampicin cd- .ferrous fumarate 238Procainamide is: a-Na channel blocker b-nifedipine clisinopril d-quinidine 239Thiazide diuretics cause all the following except : a-hypokalaemia b-hypercalcemia c-hyperuricaemia d.hypernatremia 240Elimination of digoxin is mainly by: a-kidney b.236.Trosyd® bMycospor® cZovirax® d. 4th generation cephalosporin 245.4th generation cephalosporin 246Which aminoglycoside antibiotic can be taken orally? a-gentamycin bneomycin camikacin d-tobramycin 247All these medications are used in treatment of TB except: a-cyclosporine b-INH c.1st generation cephalosporin b.cytarabine d.cyclophosphamide e-azathioprine(Imuran) 243Cefaclor is: a.242All are antimetabolites except: a-methotrexate bflurouracil c.Zinnat is: a.1st generation cephalosporin b2nd generation cephalosporin c.Cefixime is: a.2nd generation cephalosporin c3rd generation cephalosporin d.2nd generation cephalosporin c3rd generation cephalosporin d.3rd generation cephalosporin d.4th generation cephalosporin 244.cycloserin drifampicin cd- .1st generation cephalosporin b. 250Which one is not 5HT3 antagonist? a-tropisetron bondansetron c-domperidone d-gransetron 251Which is not oral anticoagulant? a-warfarin b-enoxaprine c-phenidione d-nicoumolone 252All of these are the components of calamine lotion B.fungal infections dantibiotic 254Which one is used for benign prostatic hyperplasia? a-flumazenil b-cefprozil cmivacurim d-finasteride 255All of these are 3rd generation cephalosporin except: cd- .Zinc Oxide 253Terbinafene is used topically for: aeczema b.hypersensitivity reactions.P except: a.all of the above.candida c.sod.248One of these is not like others: a-timolol bacebutalol c.labetalol d. d.propranolol 249Betahistine HCl (betaserc) used for: a. Sulphate b-calamine c-sod.for Meniere’s disease b-antihistamine c. citrate d-bentonite e. pot.sod.Oral re-hydrate solution(ORS) contains: a. cd- . chloride & sod.sod. citrate.pot.a-cifixime bcefpodoxime cceftriaxone d-cefotaxime E) none of the above 256Which of the following is not mucolytic? a-bromohexin bdextromethorphan c-ambroxol d-guaphenesin 257Which one is anti-platelet? a-ticlopidine b-desfluron c-aldesleukin d-atovouon 258All of these are anti-neoplastic except? a-aldesleukin btaniposide cpentostatin damlodipine 259-Which is not benzodiazipne? a-temazepam bnitrozepam cloprazepam dclozapine 260. chloride c. chloride. chloride & glucose b.pot. citrate. citrate.sod. pot.sod.Minimal exercise b.sod. chloride.Male gender cd- . 261Which of the following is selective α1 blocker? a-labitolol bterazosin cclonidine dcaptopril e-verapamil 262Allopurinol is used as: a-analgesic agent buricosuric agent c-antiinflamatory agent d-antipyretic agent 263Which of the following is released by bacterial infection? a-endotoxin b-exotoxin c-antibiotics d-cytotoxin 264a-25% b60% c80% d10% The amount of water in adult male is about: 265Which of the following is the first choice in acute gout? a-allopurinol b-indomethacin c-colchicine 266Which of the following is NOT a risk factor for osteoparalysis? a. bicarbonate &citric acid. sod.Low calcium intake c. citrate & glucose d. chloride. Fentanyl is considered controlled medication: a.Family history 267The latin abbreviation for “After Meals” is: a.D M bHF cCK D dHT N -27 cd- . b.a. e.true bFalse 272. a.c.a.i. d. c.c. b.Rosiglitazone is useful in treatment of: a.oral c.c.p.c.c 269Which of the following consider Parenteral Administration? aSubcutaneous b.aa d.d.c.c.true bFalse 271.all 270INH can be used for treatment of TB.p.i.c.a.c 268The latin abbreviation for “Every Night” is: a.o.c.a. c. e. d.n. Fal se cd- .3 8 gm of wa ter are ne ed ed to ma ke 16 0 gm of 5% w/ w sol uti on of K ac eta te. atru e b. .metoprolol 277.Metoprolol 279.Timolol d.Which one of the following ß blockers used as antiarrythmia as it can block K (potassium) channel a.esmolol b.which one of the following ß blockers used in ophthalmic drops for treatment glaucoma a.salbutamol b.Gentamycin cNitroglycrin d.274Which of the following are given IV rout? a.Which one of the following is considered non selective ß blocker a.betaxolol c.esmolol b.acetylcholine b. c 275The main neurochemical transmitter in the parasympathetic nervous system is a.Phenylephrine 280.Butoxamine cclonidine d.Which one of the following used as vasodilator and can be used in benign prostatic hypertrophy cd- .sotalol 278.b.Which one of the following is used as ß2 agonist? a.Atrovastatin b.sotalol c.propranolol d.Timolol d.Amphetamine 276.Epinephrine cEphedrine d.esmolol bpropranolol c. morphine 284 10 grains equal how much grams a.drops 286.aspirin b.elixir e.tolazocin bprazocin cPhentolamine d.alteplase d.streptokinase b.Heparin cd- .Which one of the following leads to constipation a.ferric gluconate b.solution b.lotion c.65 d6.65 285.urokinase c..ferroic c.5 e.which one of the following drugs doesn’t make the feces black a.ergotamine b.a.0065 b.which one of the following not be fibrinolytic drug a.emulsion d.Phenoxybenzamine 281.warfarine e.ibuprofen c.0.Methsyrgide 282.aluminum hydroxide e.The mixture of liquid paraffine and water will be a.rifampicin d.065 c.ca carbonate d.phenytoin 283.Which one of the following agents can be used as powerful oxytocic? a..ergonovine (ergometrine) cmethylergonovine d. Roacutene (isotretinoin) can be used for a.Sensory c.Cardiac glycoside d.Which one of the following shows antipyretic activity? a.mebendazol dNitroglycrine e.Atropine indicated in Glaucoma 292.Dobutamine mustn’t be taken cd- .metrinidazol c.Morphine cause diarrhea e.Ciprofloxacin is safe during pregnancy d.motor b.TB c.Vitamin D drevatives 291.287.Mixed d.a and b c.which of the following sentences is true a.acne vulgaris b.Types on nerves in the nervous system a.diclofenac Na 289.Roacutene is a.Alkaloids e.all of the above 288.Amoeba 290.alprazolam should not be used for long term b.Aspirin is safe in peptic ulcer patient c.Catecholamine bVitamin A derivative c.amiodorone b. SC e.Adrenal gland c.Dobutamin c.Ovary 297.all of the above e.ACEI 296.Phentolamine b.Addison's disease bHyponatremia c.a.betaxolol b.Antibiotic d.Serotonin cd- .None of the above 294which one of the following is not pure ß.Severe bronchical asthma d.Which one of the following is not considered endocrine gland a.Which one of the following is α agonist? a.Timolol 295Tirofiban is a.Prednisolone used for treatment a.Phenylephrine d.blocker a.Pituitary gland b.Prevent fungal growth c.IV bOrally c.prevent blood clotting (antiplatelet) b.NSAID e.IM d.all above 293.Thyroid gland dSweat glands e.Pilocarpine e.sotalol cpropranolol d.Labetalol e. all above 299The function of the thyroid gland is/are a-growth bmemory c-body tempreture denergy production e-all above 300Which one of the following has vasodilator effect a.Rantidine b.Which one of the following drugs can be used for treatment Parkinson's disease? a.Symmetrel® is a trade name used for treatment a.Digoxin cCimitidine d.Verapamil b.298.Parkinsonis m (amantadin e) c.Fever e.Prazosin dBromocriptine cd- .Cancer 302.Peptic Ulcer d.It's Parasympathomimetic b.Fluxitin 301.Which of the following sentences is true about carvedilol a.Hydralazine e.β2 e.Amlodopine c.β1 d.α and β blocker c.Diabetes b. Saline cMannitol d.(-) b.the therapeutic index is refer to relation which is a.sucralfate c.Which one of the following is considered Glimipride side effect a.atrophy at site of ingection b.(+) c.dextrose b.Given with caution dRisk is unknown e.Which one of the following is not insulin side effect? a.hyperglycemia d.Paracetamol 307. Insulin is and can be mixed with all other solutions) e.Safe during pregnancy c.aldomet 305.all are side effect cd- .(X) d.(/) 306.Insulin shouldn't be used with a.paracetamol e.enlapril b.all are side effect e.Phenobarbital 303-oxytocin is category X so it ashouldn't be given during pregnancy b.ibuprofen d.non above 304-which one of the following drugs shouldn't be taken during pregnancy a.hypoglycemia b.hypoglycemia c.all are not side effect 308 .hyperglycemia c.Aspirin (Insulin has Drug Interacton with Aspirin.e. Increase Heart rate bBronchodilator c.exercise c.a and b 312.Vasoconstriction e.d.Cephalexin c.Which one of the following drugs can't be taken orally? aEnoxaparin bAmpicillin c.Cefepime 311.Aspirin dneomycin e.Cephamandole e.Atropin 310.Warfarin 313.Insulin dMetronidazol e.The type II Diabetus Mellitus can be treated with: a-sulphonylurea b.Which of the following symptoms is due to increase epinephrine in the sympathetic nervous system a.Duphlac dBrufen e.all are not side effect 309.Mydriasis d.Cefoxitin d.all of the above cd- .Aspirin c.Which one of the following is not cephalosporin? aclarithromycin b.Which one of the following is not OTC drugs a-Bisacodyl b. Emulsion 315-ondansetron HCl is used for hypertension angina pectoris prophylaxis of migraine anti-emetic 316-all these are side effects of chloramphenicol except irreversible aplastic anemia optic neuritis peripheral neuritis iron deficiency anemia 317-ticlopidine is used for anticoagulant antibiotic anticholinergic Antiplatelet 318.all these drugs are fibrinolytic except Dipyridamole Streptokinase Urikinase 319-all these drugs can be used for parkinsonism except selgiline HCl carbidopa pergolide Nedocromil sodium 320cardiac arrest could be managed by the following except ephedrine lidocaine propranolol Normal saline cd- .Solution d. water.Suspension c.314. and oil will be a.lotion b.The mixture of acacia. 321insulin which can be given I.V. is regular type 30/70 type NPH type None of the above 322Drug used for leishmania is sodium stiboglyconate sodium cromoglyconate mebendazole 323all these drugs are antibacterial except Zalcitabine lomefloxacin cefoprazone 324all these are natural estrogens except Mestronol oestrone oestriol oestradiol 325-co-trimethoxazole contains -trimethoprim + sulphamethoxazole -trimethoprim + sulphisoxazole -trimethoprim + sulphadiazine -trimethoprim + sulphacetamide 326which one of these is the drug of choice for myxodema [hypothyrodism] Carbimazole iodine Thyroxin sodium propyl thiouracil cd- . 327benzyl peroxide is local treatment of acne vulgaris local treatment of scabies local treatment of inflammation local treatment of pain 328thiazide diuretics cause all the following except hypokalemia hypercalcemia hyperuricemia hyponatremia hyperglycemia Hypernatremia 329treatment with anti-arrythmic drug depends on except type of medciation period of medication Patient sex 330amilorid as trimetren causes CNS disturbances Hyperkalemia Hypokalemia Not affect potassium 331which one is not tetracycline minocycline demeclocycline doxycycline clindamycin 332which one is not Calcium channel blocker verapamil diltiazem amlodipine Cinnarzine cd- . 333all these drugs are used in treating T.B.M. except Cyclosporine INH Cycloserin Rifampin 334All these drugs are anti-cholinergic except iprotropium atropine sulphate benzatropine methylate Dobutamin 335which is correct about diazepam can cause muscle spasm is taken I. only is derivative from morphine is not used for long term 336maximum dose of Paracetamol is 4 gm/day 5 gm/day 7gm/day 10 gm/day 337Metoclopramide is dopamine antagonist acts central chemoreceptor trigger zone (CTZ) acts peripherally used as anti emetic all of the above 338which one is contraindicated in pregnancy sucralfate cd- . ethambutol chlorpheneramine Ciprofloxacin 339the antidote for heparin is protamine sulphate acetyl cysteine vitamin K naloxone 340the antidote for paracetamol protamine sulphate Acetyl cysteine vitamin K naloxone 341what is the generic name of vitamin B2 cyanocobalam in niacin riboflavin pantothenic acid pyridoxine folic acid 342-what is the generic name of vitamin B3 cyanocobalam in niacin riboflavin pantothenic acid pyridoxine cd- . cyanocobalamin b.Thiamin e.niacin c.fluxotine is prozac cd- .riboflavin d.cyanocobalamin bniacin c.pyridoxine f.pyridoxine f.riboflavin d.pyridoxine f.cyanocobalamin b.folic acid 347.folic acid 348.pantothenic acid epyridoxine f.what is the generic name of vitamin B1 a.folic acid 343what is the generic name of vitamin B5 cyanocobalam in niacin riboflavin pantothenic acid pyridoxine folic acid 344what is the generic name of vitamin B6 a.folic acid 345what is the generic name of vitamin B9 a cyanocobalamin bniacin c.pantothenic acid e.niacin criboflavin d.riboflavin d.pantothenic acid e.folic acid 346-what is the generic name of vitamin B12 a. P.selective serotonin reuptake inhibitor antiinflammatory drug a&b 349omepra zole is losec proton pump inhibitor analgesic a & b 350which of the following diseases that cause edema CHF Renal failure Arrhythmia a&b 351all of these are the components of calamine lotion B. except ZnO Calamine Sodium citrate Bentonite Sodium sulphate 352MMR vaccine is measles vaccine mumps vaccine rubella vaccine measles-mumps-rubella vaccine 353cd- sodium nitroprusside potent vasodilator . all these statements are wrong except it is resistant to penicillinase enzyme it is taken by oral route only it is base stable it is better absorbed than cloxacillin 356thiabendazole is one of thiazide diuretics true false (it is an anthelmintic) 357praziquantil is causes loss of intracellular calcium of worms used for malaria biltracid is the trade name a&c 358-nitrofurantoin is indicated for viral infection GIT infection Urinary tract infection URI 359-Vitamin K cd- .potent diuretic potent vasoconstrictor anti-arrhythmic agent 354a drug needs monitor for its serum level amikacin warfarin theophyllin digoxin all of the above 355for fluxacillin. increase formation of clotting factor increase conversion of vit. K to the active form prevent conversion of vitamin K back to the active form none of the above 360-quinidine sulphate is anti-arrhythmic agent antimalarial agent antihypertensive agent a&c 361ACE stands for converting Ag II to vasoconstrictor Ag I converting Ag I to vasoconstrictor Ag II converting Ag I to vasodilator Ag I converting Ag II to vasodilator Ag I 362treatment of anaphylactic reaction is initiated by immediate Hydrocortisone cimetidine human albumin Epinephrine 363introduction of emesis is not indicated in the following except caustic substance ingestion CNS Seizures Paracetamol poisoning 364the following are non sedating antihistamines except loratadine cetrizine terfenadine Famotidine 365type II diabetics is characterized by lack of response to insulin cd- . C cimetidine metronidazole 369Specific serotonin reuptake inhibitors are used as antihistaminic antidepressant antihypertensive antiemetic 370which of these has no vasodilator effect Methyldopa hydralazine enalapril prazocin 371Calcipotriol (vitamin D3 derivative.lack of response to sulphonylurea respond to dietary therapy alone slowly increasing sulphonylurea requirement 366the following are side effects of aminoglycosides except nephrotoxicity Ototoxicity eye toxicity abdominal pain (N & V) 367the following are potassium sparing diuretics except trimetren spironolactone amiloriode furosemide 368which one reduces the metabolism of other drugs in the liver rifampin vit. induce differentiation and to suppress proliferation of keratinocytes) is indicated for psoriasis hypertension calcium supplement acne cd- . B. should be unionized hydrophilic ionized hydrophilic unionized lipophilic ionized lipophobic 376side effects of insulin local reaction hypoglycemia fat dystrophy at site of injection all of the above none of the above 377one of the following is the main side effect of insulin Hypoglycemia fluid retention hyperglycemia all of the above cd- .B.drugs to pass B.372Amantadine is used for all of the following except antiviral for influenza A antiparkinsonism for influenza B 373all are viral infections except hepatitis B influenza herpes zoster Rickettsia 374at the cardiac arrest. the drug of choice is Epinephrine propranolol hydrocortisone saline solution 375. So decrease metabolism & increase response Decrease metabolism & decrease response Increase metabolism & increase response Decrease metabolism & decrease response 379Enteric coated tablets pass the stomach and release in the intestine pass the stomach and intestine release in the stomach 380all of these are true for levodopa except precursor of dopa does not pass B.four medicines including antibiotic cd- .antacid + H2 antagonist b.use more than one H2 antagonist c.B.B effective in parkinsonism Stimulate dopamine 381The conc. Of the drug on expiration date is not less than 100 % not less than 90 % from 90-110 % none of the above 382New and best therapy for peptic ulcer is a.378chloramphenicol affects liver inhibitory enzyme. acebutolol c.383all the following change the color of urine except nitrofurantoin phenazopyridine rifampcin none of the above 384which of the following is not cardioselective blocker a. sotalol d. atenolol b. You can phone the doctor to change it with Clarithromycin amoxicillin clindamycin ampicillin 386ACE inhibitors are used for the treatment of asthma migraine hypertension all of the above 387Atropine is used as pre-anesthetic to give skeletal muscle relaxation decrease saliva treat the side effects of anesthetics help the sleeping effects of anesthetics 388disulfiram is used for Treatment of chronic alcohol dependence protection of liver cells from alcoholism Prevention of conversion of acetaldehyde to acetic acid all of the above cd- . Labetalol 385a patient has a prescription of erythromycin 500 mg tablets every 6 hours and you do not have this antibiotic. Mucolytic 395-Treatment of Hypothyroidism: Cimetidin Thiamin cd- .Tolerance 392-All of the following are beta blockers except : a.Antidepressant b.Enalapril (Renitec) dPropranolol (Inderal) 393.Nadolol (Corgard) c.Nephrotoxicity c.Regular use of sublingual doses of Nitroglycerin is likely to result in : a.Peptic ulcer d.Anxiolytic agent c.Parkinson's disease bHypertension c.Childhood Eneuresis dPeptic ulcer e.Carbocysteine is an agent used clinically as : a.Hypnotic 394.Laxative b.Hepatotoxicity b.Cough suppressant c.Metoprolol (Lopressor) b.Diagnostic agent d.389The following are the indications of diazepam except antipsychotic epilepsy analgesic hypnotic 390The tricyclic antidepressant Imipramine (Tofranil) has been approved by FDA for use in : a.Buspirone (Buspar) is classified pharmacologically as : a.Narcotic analgesic d.None of the above 391. Carbimazol Thyroxine Sodium 396-Treatment of Hyperthyroidism: Carbimazole Propylthiouracil Thyroxine A and b 397-Trade name of Nifedipine: Voltaren Diamicron Zantac Adalat 398-NSAIDs means: NO side effect drugs Steroid anti inflammatory Non steroid anti-inflammatory drugs Non symptoms diseases 399-Which of the following not given IV: Suspension Emulsion Solution All of the above 400-Short acting barbiturate used as: Antidepressant Anesthetic Antiepileptic Diuretics 401-BACITRACIN used: Only parenteral cd- . Treatment of Herps: aNIFIDEPIN b.Only topically Only orally All of the above 402-Which of the following are contraindicated with Digoxin: Aspirin Spironolactone Zocor Rantidine 403-MEFANAMIC ACID is: Anticoagulant Anti-inflammatory Antibiotic Bronchodilator 404-Which of the following drugs are taken before meal? VOLTAREN AUGMENTIN GRISOFULVIN BRUFEN 405-Drugs used for the treatment of gout: COLCHICINE ASPIRIN (contraindicated in gout) ALLOPURINOL A and C 406.DIGOXIN cACYCLOVIR dcd- . carbamazepine b. phenoparbital d. phyntoin c.Maximum dose of Brufen: 1200 mg/day 3200 mg/day 4000 mg/day 200 mg/day 408.HYDRALAZI N 407. a.Antiepileptic: a. all of the above 409Scientific name of Vitamin A: Retinol Thiamine Cyanocopalamin Calciferol 410H2 receptor antagonist Cimetidine loratidine celexocib Promthazine 411Which of the following are corticosteroids? Amantadine hydrocortesione prednisoline b and c 412Scientific name of Vitamin K: Retinol cd- . Phytomenadione Niacin Riboflavin 413Trade name of Gliclazide: amoxil minidiab (glipizide) diamicron ventolin 414Generic name of Claritin: histadin adrenalin loratidine chloropheniramin 415Generic name of Buscopan: atenolol hyoscine (scopolamine) pilocarbine atropine 416Trade name of Allopurinol: profenide diurecif voltaren Zyloric 417Treatment of grand mal epilepsy: atenolol phenytoin heparin diclofenac 418-Treatment of (petit mal epilepsy): cd- . M c.fluxitin bethosuximide c.orally b.Which one these is pro-drug? cd- .a.I.S.warfarin 419Not used in Dysenteric Amoeba treatment: Gentamycin iodoquinol metronidazol diloxanide furoate 420Dose of Cephalexin: 1 gm /day 250 mg.C 424.atenolol d.V d.500mg / day 250 mg – 1000 mg / 6hr 500mg/8hr 421-All of the following are Antiarrhythmic drugs except: Quinidin Procainamide Halothane Phyntoine 422-Amino glycosides Mechanism of action: Inhibit cell wall synthesis Bind to 30S ribosome Interfere with osmosis characters Inhibit DNA transfer 423-Drug administrated……… are exposed to first-pass effect a.I. If 100 mg of the drug is administered orally and 70 mg of this drug is absorbed unchanged.central nervous system and peripheral nervous system b.ampicilline berythromycin c.rate and extent to which the drug enters the systemic circulation c.the action of the body on the drug b. the bioavilability is: a.70% d.all above 429Which of the following drug can cause addiction? abarbiturate b.a.all above 425.The nervous system is divided into: a.peripheral nervous system only c.all above 426.100% b.nasal decongestant d.brain d.all of the above 428Epinephrine is indicated for: a.levodopa d.anaphylactic shock basthma c.0% 427.remove the drug from the body d.Bioavailability is defined as: a.10% c.tetracycline ciodine d.furosemide cd- . non of the above 433All of these medications are antihypertensive except: a.furosemide c.folic acid d.all of the above 436.a and b d.vasodilators b.Captopril: a.All of these drugs are used in epilepsy except: acarbamazepine b.ferrous gluconate 434Agents used in anemia: a.diazepam c.morphine 431.timolol d.Phenytoin 432.vitamine B12 c.Antiplatelet drugs: cd- .reduce the formation of fibrin clots b.amlodipine batenolol c.warfarin d.used for treatment of congestive heart failure c.all of the above 435Anticoagulan ts: a.All of these drugs are used for general anesthesia except: a.metronidazole d.heparin c.430.nitrous oxide b.diazepam d.ferrous gluconate b. a.all of the above 441Which of the following statements are cd- .cimetidine d.mebendazol c.cloxacillin 437.are the major antibiotics that inhibit bacterial cell wall synthesis b.called beta lactams c.non of the above 438.increas e the bleedin g time b.lorazepam d.a and b 439.Drugs used for treatment of hyperlipidemias: a.cell wall synthesis inhibitors b-used for treatment of infections cauesd by gram+ve and gram-ve c.Drugs used in treatment of asthma: a.aspirin c.aminophylline bbeclomethasone c.contraindicated in patient with penicillin hypersensetivity d.lovastatin b.all of the above 440Amoxicillin and ampicillin: a.Penicillin and cephalosporin: a.the microbial resistance poses constant challenge to use d.a and b d. Ciprofloxacin: ait is a fluoroquinolones b.all of the above 445.amphotericine B cmiconazol d.a and c 442.Which of the following is not anti viral agent: aamantadine bacyclovair cribovirin dcephalexin cd- .rifampin cethambutol d.Protein synthesis inhibitors: a.naproxen b.correct about cephalosporin? a.clarithromycin d.used for treatment of respiratory and urinary tract infection d.isoniazide b.they are classified for 4th generations b.tetracyclin bgentamycin c.dos not used for treatment urinary tract infection ccefoxitin is a cephalosporin derivatives d.all of the above 443.Drugs used for treatment of tuberculosis: a.nystatin 446.it is bactericidal c.Which of the following is not anti fungal agent: a.all above 444. cresol c.Drugs used for treatment of allergies: a.indomethacin d.all of the above 450-Thrombocytopenia means: Increase platelets Decrease Platelets Decrease RBCs Increase RBCs 451-Generic name of Aldacton: aldhyde spironolactone aldosterone phenyl ephrine 452-tochopherol is Vit K cd- .447.chloropheniramine maleate b.Which of the following drugs are used for constipation? a.bisacodyl b.Which of the following drugs are disinfectant s: achlorohexidi ne b.a and b 449.castor oil d.magnesium sulphate c.iodin d.all of the above 448.diphenhydramine hydrochloride c. leukemia dCNS.All above 458. 455-Which of the following have local effect? Insulin spironolactone lidocaine non of the above 456-sulphinpyrazone is: Analgesic Antiinflammatory Antipyretic Stimulate uric secretion 457-WFI characterized by: a.Vit E B-complex Vit C 453-Patient received Amiloride + Captopril the excepected side effect is: hypercalcemia hyponatremia hyperkalemia hypokalemia 454-Cerivastatin withdrawal from the market because it causes: arhabdomyolysis b.Free from Ca and K c.Free from sodium b.Tween 20 is: deflocoulant cd- (uricosoric) .Pyrogen free d.osteomylitis c. 200 461-Crystalline insulin is: Cloudy Clear Unclear Non above 462-Increase Temperature means: Hypertension Hyperthermia Hypothermia Thermal 463-Increase Heart rate: Tachycardia bradycardia arrhythmia CHF 464-Decrease Heart rate: tachycardia bradycardia arrhythmia CHF cd- .140 100.lipohpilic surfactant preservative hydrophilic surfactant 459Drug used in treatment of Hypotension: -Dolobid (Diflunisal) NSAID -Doloxene (Dextropropoxyphene).Normal heart beat: 100.opoid -Dilitiazem -Dopamine 460. : 9% 4.β1 b.H2 receptor c.465-Normal saline conc.9% 90% 466-Intrathecal means injection into: Joints Spinal cord Heart Muscle 467-anti lice's: topical steroid antibiotics parathion non above 468-Most common drops: Solution Suspension Emulsion Oint.α2 d.5 % 0.H1 receptor b.H3 receptor d. 469-Sedating antihistaminic acting on: a.α1 c.H4 receptor 470Noradrenalin affects all these receptors Except: a.β2 471Megaloplastic anemia is a side effect of: Midazolam ketamine Nitrous oxide cd- . 1 ml b.50 micro liters c10 micro liters d.5 ml 473-Methadone used in: Severe pain Morphine dependence Euphoria Respiratory depression 474-H2o + Nacl final will be: Suspension Emulsion Solution Lotion 475-Which of the following are Anticholenergic? Atropine Homatropine Scopolamine All above 476-Generic name of Vasotec: Ramipril Enalapril Captopril Lisinopril cd- .Sevoflurane 472Suitable volume for ophthalmic preparation is: a. 477-Trade name of Clindamycine: Dalacin Ceporex Klacid Vibramycin 478-Which of the following is Catecholamine? Epinephrine Norepinephrine Serotonin Dopamine All above 479-Generic name of Renetic: Captopril Lisinopril Perindopril Enalpril 480-β blocker used in: Treatment of Arrhythmia Treatment of Hypertension Treatment of Angina pectoris All above 481-Cefixime is: First generation Cephalosporin's Second generation Cephalosporin's Third generation Cephalosporin's Fourth generation Cephalosporin's 482-Cefoxitin is: -First generation Cephalosporin's -Second generation Cephalosporin's cd- . -Third generation Cephalosporin's -Fourth generation Cephalosporin's 483-Maximum dose of Aspirin: 300 mg 5000 mg 4 gm 1000 mg 484-Cinnarzine used in: Hypertension Depression Peptic ulcer Prophylaxis from migraine (Meniere’s disease) 485-Generic name of Cialis: sildenafli pravastatin verdenafil Tadalafil 486-Trade name of Benazepril: capoten Renitec Zestril Cibacen 487-Generic name of Capril: diclofenac potassium Captopril Carbamazepine Cefixime 488-Generic name of Zestril Prendopril Benazepril Lisinopril Quinapril cd- . 489-Generic name of Elyzol: Metronidazole Metrizamide Loperamide Allopurinol 490-Trade name of Prindopril: Capozide Amoxil Ceporex Coversyl 491-Co-Renitec is: Captopril + Hydrochlorothiazide Enalapril+ Chlorothiazide Enalapril+ Hydrochlorothiazide lisinopril + Indapamide 492-Generic name of Acuitel is: Ramipril Lisinopril Fosinopril Quinapril 493-Chlorothiazide is: Loop diuretics potassium sparing diuretics Osmotic diuretics Thiazide diuretics 494-Cefaclor is: Cephalosporin Antibiotic β blocker Aminoglycoside Antibiotic Macrolide Antibiotic cough suppressant 495-Atenolol is: Cephalosporine Antibiotic β blocker Aminoglycoside Antibiotic Macrolide Antibiotic cough suppressant 496-Clarthromycin is: Cephalosporine Antibiotic β blocker Aminoglycoside Antibiotic Macrolide Antibiotic cough suppressant cd- . 497-Amikacin is: Cephalosporine Antibiotic β blocker Aminoglycoside Antibiotic Macrolide Antibiotic cough suppressant 498-Pholcodine is: Cephalosporine Antibiotic β blocker Aminoglycoside Antibiotic Macrolide Antibiotic cough suppressant 499-Non OTC drug: Malox Bisacodyl Acetamenophen Acetylsalicylic acid Tetracycline 500-Carbidopa used in treatment of: Parkinson's Anxiety Leprosy Amoeba Epilepsy Muscle inflammation 501-Metronidazol used in treatment of: Parkinson's Anxiety Leprosy Amoeba Epilepsy 502-Ibuprofen used in treatment of: Parkinson's Anxiety Leprosy Amoeba Epilepsy Muscle inflammation cd- . Parkinson's b.Leprosy dAmoeba eEpilepsy f.503-Diazepam used in treatment of: a.Muscle inflammation 504-Phenytoin used in treatment of: Parkinson's Anxiety Leprosy Amoeba Epilepsy 505-Amiodarone used as: Oral Anticoagulant Heparin Antagonist Antiplattlet Antiarrhythmic Parenteral Anticoagulant 506-warfarin used as: Oral Anticoagulant Heparin Antagonist Antiplattlet Antiarrhythmic Parenteral Anticoagulant 507-Protamine sulphate used as: Oral Anticoagulant Heparin Antagonist Antiplattlet Antiarrhythmic cd- .Anxiety c. Angiotensin converting Enzyme Inhibitor: Enalapril Isradepine Metoprolol Pergolide Phenyl Ephrine 512-α Agonist: Enalapril Isradepine Metoprolol Pergolide Phenylephrine cd- .Parenteral Anticoagulant 508-Heparin used as: Oral Anticoagulant Heparin Antagonist Antiplattlet Antiarrhythmic Parenteral Anticoagulant 509-Aspirin used as: Oral Anticoagulant Heparin Antagonist Antiplatelet Antiarrhythmic Parenteral Anticoagulant 510-Ca channel blocker: Enalapril Isradepine Metoprolol Pergolide Phenylephrine 511. Clopidogrel 518.NPH b.513-Not pure B-Blocker: a.warfarin cancord d.Mixtard cActrapid d.Aspirin cTiclodipine cd- .b.All of these Anticoagulant except: a.Indral b.non above 514.heparin b.Atenolol cTrandate d (Labetalol) e.Renetic 517.which type of insulin taken orally: a.Ticlid® is: aDipyridamol b.Fosinopril is: a-Staril bcapoten cAcutil d.Insulin not taken orally 515.Regular insulin characters: a -clear b -colorless c -watery d -all of the above 516. Dopamine dDobutamine e. category A Pregnancy category B Pregnancy category c Pregnancy category D Pregnancy category X 520Aceta b is: aRamipril bCaptopril clisinopril d. c.Enoxaparine 519The meaning of drug that is absolutely contraindica ted in pregnancy by FDA : a.All of them cd- . e.Serotonin h.Enalapril 521. d.Epinephrine bNorepinephrine c.Which of these is/are catecholamine's: a.d. Pregnancy b. All of these are used in T.I.Treatment of Indigistion 527Natural emulsifying agent is: aSpan b.Adrenergic agonist 525.all of them 523.H b.Acacia c.522.None of them -526 Imigran used for: a.Atropine dBenzatropine e.Muscarinic Antagonist d.B except : a.Tween d.Narcotic drug d.Which is not parasympatholytic: a.ethambutol e.Hyocine bOmeprazole c.Cycloserine cRiafampin d.Antibiotic c.all above cd- .Bethanecol is: aMuscarinic agonist bAdrenergic antagonist c.Cyclosporine 524.Treatment of diaharrea cTreatment of migraine d.N.Corticosteroids e.H2 antagonist b.Treatment of Amoeba b.Which of the following can't taken without prescription: a. Antibiotic b.528Injection in spinal fluid called: a.Antihistamine 531Cilazapril trade name is : a.Propantheline bromide is: a.Anti muscarinic cd- .Anticoagulant cAntacid d.Enalapril b.Diarrhea b.all of them 530Terfenadin e is: a.Zestril 532Zelaic acid used for: a.Acne 533.Intrathecal injection bIntramascular cIntrapretonial d.Capoten cVascase d.Intraarticular 529which of these is fibrinolytic: aUrikinase bStreptokinase cAlteplase d.Antiprotozoal bAntibiotic c.Antifungal cAntiemetic d. 100 mg (0.3 gm d.10 mg b.5.Antihistaminic 534Acenocoumarol is a.300 gm b57 gm c.01 mg c.d.a and b 536.1000 mg 538-Best rout of administration for Chloramphenicol is: Oral Parenteral Topical (eye.7 gm 537-How many grams of substance X are needed to prepare 100 cc from solution 1:1000 ? a.Daptomycin is : a.How many grams of water are used to prepare 60 g of potassium acetate solution have concentration 5% w/w: a.Antiplattlets 535.0.Antiviral bAntibiotic cAntifungal d.Anticoagulant (oral) bAntiarrhythmic cAntihypertensive d. ear. skin) S.1g) d.c Inhalation cd- . Nausea cDiarrhea dRespiratory depression eAddiction 543Epinephrine is not given orally because : a.Analgesics bcd- .Miosis b.It is rapidly inactivated in circulation 544Various opiates may be used as all of the following except : a.It is inactivated in the gastric mucosa b.Local vasoconstriction inhibits absorption c.Which of the following is not a side effect of codeine? a.539-Most of drugs are: Weak acids Weak bases Strong acids Weak salts Strong salts 540-Malaria is: Bacteria Fungus Virus Protozoa 541-One of these substances not medically used: Morphine Codeine Heroine Phenobarbital 542-. Fruit juice e.Anti-inflammatories c.Maprotiline (tetracyclic antidepressant) c.Pupil constriction b.Which of the following action is not seen with sympathomimetics? a.Imipramine HCL cd- .Nortryptiline d.Antitussive 545.Systemic blood vessel constriction 546.Albuterol e.Increased heart rate c.Pirbuterol b.Chlorthalidone c.Metolazole 547.Which of the following diuretics do not cause potassium loss? a.Bronchiole dilation d.Candy cGlucose d.Terbutaline d.Possible treatment of Hypoglycemia does not include: a.Salmetrol c.Which of the following drugs is not a Tricyclic Antidepressant? a.Which of the following beta-adrenergic agents is not short acting? a.Triamterene dHydrochlorothiazide e.None of the above 548.Furosemide b.Glucagon 549.Antidiarreals dAids to anesthesia e.Insulin b.Trimipramine b. Inhibit an enzyme c.Molecular size e.Captopril and Enalapril do all the following except: a.Increase rennin concentration in blood b.Cough suppressant d.Lipid solubility bPlasma protein binding c. Polarity d.All of the above 554.Most drugs are aStrong electrolytes bWeak electrolytes cNon cd- .Competively blocks Angiotensin || at it’s receptors d.All of the above 552Salicylic acid is used primarily as an (a) a.Keratolytic agent 553Which of the following factors affect the distribution of a drug? a.Analgesic bAntipyretic c.Lipid solubility b.Which of the following factors affect the distribution of a drug? a.Raises the blood Potassium concentration 551.550.Polarity dMolecular size e.Uricosuric agent e.Plasma protein binding c. Cobalt e.Manganese 557.Niacin c.Which of the following is classified as fat soluble? a.Powdered sucrose 556.Ascorbic acid dThiamine hydrochloride e.Riboflavin 559.electrolytes dHighly ionic eNone of the above 555-The most common disintegrator in compressed tablets is aDextrose bLactose cStarch dPotassium bitartrate e.Lubricants d.Disintegrators b.Glidants c.Ophthalmic solutions should be formulated to include which of the following? Sterility cd- .Both b and c 558.Binding agents e.Vitamin d b.Which of the following is found in vitamin b12? aMagnesium b.Gums are used in tabletting primarily as a.Nickel cIron d. Activated charcoal is used in some antidotes because of which of its properties? a.too little levodopa in the brain c.too much dopamine in the brain 563.too little dopamine in the brain b.Parkinson is probably due to a.Stabilizing 562.Absorptive dAdsorptive e.Is otonicity Buffering all above 560Advantag es of tablets over liquid dose forms include the following Enhanced stability Ease of administration Greater accuracy of dosing All above 561.Emetic c.Cyclosporine is used for cd- .too little acetylcholine in the brain d.too much levodopa in the brain e.Neutralizing b. Preanesthetic agents 567.Anesthetic 568.Antiarrhythmic e.Orlistat is used as a(an) a.Weight loss agent d.Anti-parkinsonian agents e.allergies b.Antiepileptic e.General anesthetic b.anthelmintic 566.Sedatives b.Hypnotics cAntispasmodic agents d.Pantoprazole is used primarily to treat a.gastric hyperacidity bhypertension c-cardiac insufficiency dgout e.Antipruritic cPreanesthetic d.Narcotic analgesic c.Lidocaine is used as a local anesthetic or as a(an) a.Analgesic cd- .Narcotic antagonist b.Prevention of transplant rejection dsteroids deficiency e.Ultra-short acting barbiturates are used primarily as a.angina c.a.diuretic bcardiotonic cantidepressant SSRI d-antiinflammatory e.treating lead poisoning 564.migraine headache 565-citalopram is a (an) a. Kidney failure d. Estrogen b.Castor oil is classified as which type of laxative? a. Replace pepsin 571. Worm infestations b. Ulcers c. Irritant d. Testosterone e.Tamoxifen is classified as a(an) a.Gold compounds have been used to teat a.569Which of the following is classified as a cholinergic antagonist? a. Promote carbohydrate degradation d. Anthraquinone c.Acetylcholine b. Treat muscle injuries e. Psoriasis 572. Treat digestive disorders c. Stool softening e. Dissolve blood clots b. Lubricating b. Androsterone d.Neostigmine c. Bulk producing cd- . Rheumatoid arthritis e. Thyroid hormone 573.Bethanecol eMethacholine 570Streptokinase is used to a.Atropine d. Anti estrogen c. Amiloride (Midamor) 578.4.0 d.Acetazolamide (Diamox) c.0 b.2.Uric acid b.8.Antiestrogen c.6.Enstrogen dProgestin e.The appropriate PH range for ophthalmic products is a.0 to 8.Indapamide (Lozol) b.Chlorthalidone (Hygroton) dTorsemide (Demadex) e.Urea c-Sodium dBicarbonate e.0 to 10.0 to 6.releasing hormone analog b.Creatinine 579.Androgen 577.0 c.574-Albuterol is : Alpha receptor antagonist Alpha receptor agonist Beta receptor antagonist Beta receptor agonist Alpha and Beta receptor agonist 575-Which of the following is (are) dopaminergic antiparkinson agents? Bromocriptine (Parlodel) Pergolide(Permax) Selegiline (Eldepryl) All above 576-Tomoxifen (Nolvadex) is an agent that can best be described as : aGonadotropin.0 to 3.The thiazide diuretics decease the excretion of a.Which one of the following agents is classified pharmacologically as a carbonic anhydrase inhibitor a.0 cd- . Preanaesthetic 584.580.Antacid bAntiflatulent cConstipating agent d.Laxative 585.All of the above 581Sucralfate is used to treat a.General anaesthesia bAntipruritic cAntiarrhythmic d.Dermatological reactions bDepression c.Side effects of isotretinoin (Roaccutane) include a.Lidocaine is used as a.Simethicone is a\an a.Prolactin inhibitor 583.Peptic ulcers bCarcinoma c.Teratogenicity d.Which of the following drugs is the choice for the treatment of all forms of Schistosomiasi s aPrazaquantil cd- .Calcium depletion d.Obesity 582Methyldopa is used as a /an aAntiparkinsonism bSedative cAntihypertensive d. Is not recommended for post.Has an anti.Ofloxacin d.Pieracillin c.inflammatory activity similar to aspirin c.for a 4 year old child.bMebendazole c.Anti depressant bH1 receptor antagonist cH2 receptor antagonist d.Niclosamide dThiabendazole 586Famotidine is classified as a.480 mg c.Polysorbate 80 588.Which of the following is a natural emulsifuing agent a.All the following are considered to be beta – lactam type antibiotics.Acacia b.Paracetamol a.Imipenem cd- .May cause severe liver toxicity if taken in overdose 589.immunization in 2-3 month old b.Ceftriaxone b.240mg b.Polysorbate 20 d.Beta 2 agonist 587.Is an effective analgesic in severe renal colic d.EXCEPT a. the maximum daily dose of paracetamol is a.1 g d.Lactose c.2 g 590. 2001 b.Imipenem cStreptomycin d.Vomitting bConstipation c.a medicine expires "January 2001" it must not be used after a.0.The normal range of FASTING blood glucose is a.Ampicillin 596.Allopurinol d.Methylxanthine cMast-cell.010g ccd- .2001 d.Abeta-agonist b.Nausea.90-110mg/dL 597.Which of the following is not a beta-lactam antibiotic a.Diarrhoea d.Muscarinic antagonist 594.Sodium salicylate 592The most common side effect related to the use of Aluminium containing antacids is a.75-150mg/dL c150-180mg/dL after meal d.January 01.Aspirin b.2001 c.Aztreonam b.Colchicine c.January15.stabilizer d.December 31.2001 595.The dose of a drug is 0. old child who weighs 20 Kg approximately a.Gl bleeding 593Salmeterol is a a.591Which of the following drugs inhibits the formation of uric acid a.003g b0.5 mg/kg What dose should be given to a 6 yr.January 31.55-75mg/dL (60100) b. Famotidine d.Domperidone (Motilium) bDoxycycline (Vibramycin) cChloramphenicol (Chloromycetin) d.The principal toxic effect of Heparin is a.033g d0.Astemizole (Hismanal) 599.05g 598Which of the followi ng is not indicat ed for use in childre n less than 12 years old a.0.Metoclopramide 600.Hair loss cd- .H2 receptor antagonist aOmeprazole bSucralfate c.Bronchospasm b.Chills c. d. M Usman Khan … All answers are correct… Errors and omissions accepted) cd- .Hemorrhage (Prepared by Dr. Which of the following drugs is the drug may cause discolouration of nail beds and mucus membranes?i a.MAOI’s b.Rifampicin .Pyrimethamine c.Famotidine i5.Prophylaxis of hereditary angioedma d.Cisapride d.Which of the following drugs does not cause insomnia ?i a.Tetracycline b.Cimetidine d.Nizatidine b.Chloroquine c.Beta blockers d.Which of the following drugs is a systemic amoebicide?i a.Domperidone c.Which of the following is a lipid lowering drugs ?i a.Emetin d.Prevent heammorhage due to Heparin overdose i2.Acipimox i4.Doxycycline d.Which of the following H2 receptors antagonist has the highest affinity for cytochrome p450 ?i a.Lansoprazole d.Diarrhea d.Constipation c.Ranitidine c.Belching b.Which of the following is not an indication for Tranexamic Acid ?i a.Sodium Stibogluconate i8.Treatment of heamorrhage associated with excessive fibrinolysis b.An antidote for Streptokinase overdose c.Which of the following is a dopamine antagonist?i a.Blurred vision i6.i1.Aprotinin b.Barbiturates i3.Tranexamic acid c.Caffeine c.Which of the following side effects will be caused by antacids containing NAHCO3?i a.Loperamide i7.Granisetron b.Diloxamide furoate b. 4) to the trace elements (A-D) listed below. Promotes wound healing and normal growth(A) (i4.Which of the following drugs can be used for the treatment of influenza A infection ?i a.Cod liver oil b.Sodium Stibogluconate d. Helps maintain normal glucose m etabolism(C) i16.Which of the following drugs is used in the treatment of Leishmaniasis?i a.Iodized salt i15.Copper c.Biotin d.Corticosteroids .It is safe in infections caused by Chlamydia d.Chromium d. each answer may be used more than once a.Pencillamine c.Match the statements (1.Cyanocobalamin i14.It is contraindicated in pregnancy c.Niclosamide d.Folic acid c. Protects cells against damage during cellular m etabolism(D) i3.Match the drug characteristics (1.Kelp d.each answer may be used more than once a.Which of the following drug will antagonize Methotrexate?i a.Praziquantel b.Sea food c.Thiabendazole i10.Thiamine b.Diloxamide c.Emetin i12.Zinc b.Auranofin b.4) with the drug listed below (a-d).Which of following drugs is the drug of choice for the treatment of all forms of Schistosomiasis?i a.Vidarabine i11.Pyrimethamine b.Aspirin d.Selenium i1.It is useful for the treatment of resistant strains b.i9. Formation of red and white blood cells(B) (i2.Which one of the following statements about tetracycline is not correct?i a.Ribavarin d.Zidovudine(AZT)i b.It can lead to discolouration of teeth if given to children i13.lodine is found in all of the following except:i a.Amantadine c.Mebendazole c. Cycloserine c.4) list the most likely cause (a-d).Pyridoxine requirements may increase during administration of all the following except:i a.P i20.Benzalkonium chloride solution NF i21.it is important that she receives daily supplements of :i a.Sodium Bicarbonate b.Vit B6 c.Dopamine receptors in the brain d.Aluminium Hydroxide c.Acetylcholine receptors in the brain c.Bone marrow toxicity c.Renal failure d. each answer may be used more than onces a.Vit A b.Magnesium Hydroxide i1i2i3i4- May cause diarrhea(D) Should not be used by patient of heart failure(A) May cause dry mouth(C) Can be incorporated with an antacids mixture to control diarhoea(B) i18.Skin reaction b.Syrup simplex b.Serotonin receptors in the brain b.Aluminium acetate topical solution USP c.Strong iodine soluotin USP b.this is a severe:i a.Wich of the following solutions is used as an astringent?i a.i1.Platelet function effect© i2.Acetic acid NF d.Folic acid d.receiving carbamazepine becomes pregnant.Riboflavin .Given on an empty stomach(B) i(4.anextrapyramidal adverse effects is caused by the blocking of:i a.Oral form of gold(A) i3.All of the following preparations contain alcohol except:i a.Levodopa i19.May be given intra articularly(D) i17.CNS suppression i23-If a women.Belladona tincture B.Amitriptyline d.Isoniazid b.Dopamine receptors outside the brain i22-A rare side effect of some anticonvulsants is Stevens-Johnson syndrome.Aromatic ammonia spirit USP c.Terpin hydrate elixir USP d.for each side effect (1.Oral contraceptives d. Which of the following is a quinolone antibiotic ?i a.Close tightly after use d.It is inactivated by gastric acid b.It is absorbed better after foods i29.Containers must be made of glass and be covered with a tight-fitting ----l c.Diphtheria c.2 months d.Mycoplasma b.Hydralazine b.Hirsuitism c.Chlortetracycline c.Scarlet fever i32-in the treatment of pulmonary tuberculosis.Minoxidil c.Gingival hyperplasia d.Guanethidine i26-Nitroglycerin-all the following are true except :i a.CNS stimulation c.Clindamycin b.Micrococcus d.T e.Can be dispensed in hospital pack of 500 and 1000 tabs b.All of the above i28-Which of the following is true about Penicillin V ?i a.Microbacter i31-pertussis is another name for :i a.Prazosin d.It is more active than Benzylpencillin d.Gastric irritation e.Clarithromycin i30-Tuberculosis is caused by a :i a.4 months c.It is acid stable c.1 month .Whooping cough d.Acne b.Tachycardia b.b.i 24-Which of the following are side effects of phenytoin treatment?i a.and c i25-Which drug is considered as Alpha-1.Ciprofloxacin d.a.Adrenergic blocker : i a.Tablets must be stored at controlled R.Tablets not to be refrigerated i27-The most important adverse reaction to terbutaline is :i a.Fine muscle tremor d.Mycobacterium c.Cough b.6 months b.antibiotic treatment must be continued for at least :i a. Congestive heart failure c.As a urinary acidifier b.Acute systemic anaphylaxis should be treated immediately by IV injection of adrenaline c.Oral d.Minoxidil .Verapamil hcl b.Atrial fibrillation i38-streptokinase is indicated for the treatment of :i a.In the treatment of tuberculosis d.Nefedipine c.Impaired fat absorption b.Atrial flutter b.i33-all of the following are prodrugs except :i a.Antagonizing the opening of the fast sodium channel d.Ventricular tachycardia d.Captopril d.Sulphonylureas are oral anticoagulants d.Sulindac b.Inhalation c.Preventing entry of calcium channels through slow channels b.As an antifungal agent c.Sublingual i35-which of the following statements is/are correct?i a.Intravenous b.None of the above i36-verapamil exerts its effects through which of the following actions?i a.None of the above i37-cardiac glycoside may be useful in treating all of the following except :i a.Enalapril d.Diazepam c.Psoriasis i39-tretinoin is used therapeutically :i a.Increasing sodium entry c.Pulmonary emboli c.Tuberculosis d.In the treatment of acne i40-a calcium channel blocker that is used parenterally for cardiac arrythmias is :i a.Sulfasalazine i34-which route of drug administration is likely to subject a drug to first pass effect ?i a.Ketamine is used in the treatment of migraine b. Peptic ulcer d.i41-Wich of the following has not been used for the treatment of Parkinsonism ?i a.Hypertension c.Omeprazole d.Tolerance i47-All of the following are beta blockers except :i a.Pentoxyfylline c.Naloxone hcl (Narcan)i b.Constipation c.Glibenclamide b.Inhibition of the synthesis of prostaglandins c.Pindolol b.Hepatotoxicity b.Propranolol (Inderal)i i48-Bisacodyl frequently can cause :i a.An anticoagulant effect b.Lisinopril i43-The anti-inflammatory effect of aspirin is due to :i a.Kemadrin i42-The drug that is most likely to induce bronchospasm is :i a.Cogentin b.Nephrotoxicity c.Pentazocine (Sosegon)i .Eneuresis d.Desmopressin acetate i45-The tricyclic antidepressant Iimipramine (Tofranil) has been approved by FDA for use in :i a.Parkinson's disease b.Insulin c.Peptic ulcer e.Tofranil d.None of the above i46-Regular use of sublingual doses of Nitroglycerin is likely to result in :i a.Metoclopramide d.An antigen-antibody reaction d.Enalapril (Renitec)i d.Skin rashes d.Abdominal cramps b.Metoprolol (Lopressor)i b.Dizziness i49-An example of a pure opioid antagonist :i a.All of the above i44-The most useful drug in the treatment of diabetes insipidus is :i a.Artane c.Nadolol (Corgard)i c. Anxiolytic agent c.Digoxin b.Nalbuphine(Nubain)i d.Nitroglycerin d.Nifedipine c.Diagnostic agent d.c.Calcium channel blockade d.Both a and b d.Analgesia c.The vegetative stage b.None of the above i57-Which of the following is not a storage area for iron:i a.Narcotic analgesic d.Contraindicated in children d.Flucloxacillin(b) i4.Cough suppressant c.The sporing stage c.Psoriasis i51-Buspirone (Buspar) is classified pharmacologically as :i a.Kidney c.Reticuloendothelial system b.Cough depreaaion b.Hepatocytes d.Morphine i50-Carbamazepine (tegretol) is used for treatment of :i a.Cilastin(d) i56-Disinfectants are expected to destroy or inhibit the growth of microbes which are in :i a.Betalactam antibiotic active against pseudomonas b.Mucolytic i54-The following drugs may be given by sublingual route except :i a.Isoprenaline i55-Match the following antibiotics to the best description given below (a-d)i a.Laxative b.Muscle .Hypnotic i52-Dilitiazem is used primarily for its ability to produce :i a.Antidepressant b.Eneuresis b.Attention of defict disorder d.Pencillinase resistant betalactam c.Inhibits renal m etabolism i1.Piperacillin(a) (i2.Tetracycline(c) i3.Emesis i53-Carbocysteine is an agent used clinically as :i a.Trigeminal neuralgia c. Bum etanide c.Methyl testosterone i63-Which of the following Vitamins is essential in the formation of Prothrombin?i a.Antihistamine c.Methyldopa b.Diphenhydramine i65-Which of the following Local Anaesthetics is useful for topical administration only?i a.Pethidine c.Bupivacaine c.Frusemide i59-One drop has a volume of :i a.Vitamin E d.0.Methadone d.0.Codeine d.Noscapine b.Methyldopa c.Mefenamic acid b.Lidocaine b.5 ml b.i58-Which of the following is a sulphonylurea antidiabetic drugs?i a.Ferrous sulphate b.1 ml c.Iron-sorbitol citric acid .Vitamin A b.Chlorpropamide b.Variable.Corticosteroid i61-Which of the following drugs is a vasodilator?i a.Iron-dextran c.Procaine i66-The iron preparation given by the intravenous route is:i a.Mexitilline c.Acetazolamide d.Astringent d.Vitamin K i64-Which of the following is not used as an antitussive ?i a.Benzocaine d.Prazocin d.Anti-inflammatory b.15 ml d.0.Ferrous gluconate d.Vitamin B complex c. depending on the liquid and the dropper i60-Ketorolac is used in eye preparations as a/an :i a.Propranolol i62-Which of the following drugs is not associated with haemolytic aneamia?i a. Trimethoprim / Sulphamethoxazole i70-The maximum daily dose of Glibenclamide is a.Perphenazine d.20 mg/day d.Vitamine D c.Corticosteroid i75-Which of the following is not used as aprophylaxis for migraine?i .Anti tussive b.Caffeine i73-Opioids have the following uses except:i a.Vitamine E b.Antihistamine b.Analgesics d.Anti microbial c.Anti-inflammatory c.30 mg/day i71-Which of the following is not used to treat psychosis?i a.Phenylephedrine c.Gaviscon b.Aluoxetine b.2.De-nol d.5 mg/day b.Vitamine A d.Epinephrine / Lidocaine b.Haloperidol c.5 mg/day c.Ephedrine b.Anti inflammatory d.Resperidone i72-A sympathomimetic often present in OTC appetite suppressant is:i a.Phenylpropanolamine (PPA)i d.Zantac i69-Which of the following drug interactions is not used therapeutically?i a.Vitamine K i68-Which of the following is recommended for dyspepsia in pregnancy?i a.Pseudoephedrine / Salbutamol d.i67-Carotenoids are precursors for which vitamin?i a.Pre anaestetics i74-Levocabastine is a/an:i a.Pylorid c.Probenicid / Penicillin c. Throat infections i81-Percentage of total body iodine in thyroid glands is :i a.Cough c.Hypertension d.1 litres b.90% d.Isophane insulin b.Throbbing headache c.Growth retardation d.Nausea b.Skin rash i77-All of the following are common iodine deficiency symptoms except:i a.Treatment of pituitary diabetes insipidus c.Treatment of polyuria caused by hypercalceamia b.1 .Insulin zinc suspension d.Soluble insulin c.Decrease chest pain in refractory unstable angina d.5 litres c.1.Asthma b.Intellectual disability c.75% c.3 mg %i .Increasing uterine contractivity i80-oral sympathomimetic decongestants should be avoided in patients who have:i a.0.a.Hypertension d.Pizotifin b.1.Metoprolol c.Propranolol i76-The most common side effect of sublingual glyceryl trinitrate is:i a.Decreased early and late pregnancy miscarriage i78-Which of the following insulins has the shortest duration of action?i a.Goitre b.5 .2 litres i83-Normal serum bilirubin is :i a.50% b.8 litres d.Protamine zinc insulin i79-Vasopressin (ADH) is used therapeutically for:i a.1 mg %i b.Prazocin d.95% i82-Daily saliva secretion is :i a. Hypothalamic function d.Pituitary function c.AB negative b.Protein i87.Major pathway of excretion of Calcium is :i a.Increase concentration of bile c.B+ve or AB+ve d.FSH and LH only b.Decreased RBC formation d.Increase gluconeogenesis c.Decreased WBC formation c.Adrenal and testicular function b.Bicarbonate c.Increased RBC formation b.A+ve or AB+ve b. Progestrogen and Androgen d.5.Pancreatic function i89-Which blood can be safely given to a patient of blood group AB positive?i a.Increase intrabiliary presence d.A positive c.O positive i90.Oestrogen.Kidney .All of these i85.Increase phosphate level i91-Insulin causes :i a.5 mg %i i84-Ovary secretes :i a.4 mg %i d.Phosphate d.Increase glucose m etabolism b.c.A-ve or AB-ve c.Reticulocytosis indicate :i a.Increase lipolysis d.4 .Increased WBC formation i88-Ketosteroids in urine include :i a.The absence of anti-A and anti-RH agglutinin plasma means that the subject is :i a.Oestrogen and Progestrogen only c.Acetate b.Type O i86-The most important buffer in extracellular fluids is:i a.Function of gall bladder is :i a.3 .B positive d.Increase glycogenolysis i92.Increase alkalinity of bile b. Insulin i94.Causes lipogenesis d.Electrons and Protons d.Increase level of Calcium c.Serotonin c.Which of the following is the fastest to be absorbed from the stomach?i a.Somatostatin d.Fats d.adrenal medulla i96.germ cells d.Which neurotransmitter controls secretion of prolactin?i a.The following are true of insulin except :i a.Secreted by beta cells c.Angiotensin b.Increase level of Potassium i100.Water i99.Electrons b.spinal cord b.thalamus i95.Gut c.Testosterone is secreted by :i a.b.First relay station of pain is :i a.None of the above i93.sertoli cells b.Medulla c-pons d.Carbonhydrate b.Promotes glycogenesis .Proteins c.Function of calcitonin is to :i a.Protons and Neutrons i98.Decrease level of Calcium b.Epinephrine d.Nucleus of a atom contains :i a.leydig cells c.Increase level of Mg d.GABA i97.Only Protons c.The secretion of aldosterone is controlled by :i a.Kidney and Gut d.Glycopeptide b.Dopamine b.ACTH c. All of the following are natural estrogens or congeners except :i a.Which of the following statements about propylthiouracil is false ?i a.Estradiol b.Vagal arrest of the heart e.It interferes with the effectiveness of exogenously administered thyroid hormones i5.Addiction i7.Gelatine d.Local vasoconstriction inhibits absorption c.Vomiting d.Oxidation b.It is used for treatment of hyperthyroidism b.Diarrhea d.Acacia b.Reduction d.It diminishes peripheral deiodination of T4 and T3 d.Estropipate i8.It is rapidly inactivated in circulation d.Which of the following symptoms is not present in digitalis intoxication?i a.Respiratory depression e.Miosis b.All of the following are diuretics except :i a.AV block b.Nausea c.Deamination c.Diethylstilbestrol c.None of the above e.It inhibits iodide oxidation e.Ethinyl estradiol e.All of the above .Aminophylline b.Tragacanth i3.Epinephrine is not given orally because :i a.Spironolactone d.Visual disturbances i4.Conjugation i2.Veegum e.Bum etamide e.Estrone d.It inhibits the synthesis of thyroid hormones c.It is inactivated in the gastric mucosa b.Which of the following is not a side effect of codeine?i a.Wich of th following is not a major pathway or type of biotransformations ?i a.Chlorthalidone i6.Which of the following is not a naturally occurring emulsifier?i a.Glyburide c.Cholesterol c.i1.Hydrolysis e.Ventricular tachycardia c. It is non selective alpha antagonist i14.Amrinone e.Anti-inflammatories c.Propranolol penetratesin to the CNS c.All of the following statements about propranolol are true except :i a.Sweat gland stimulation d.Oubain c.Sulfisoxazole e.Insolubility b.Docasat i12.Which of the following drugs is not a proton pump inhibitor ?i a.Rabeprazole c.Dogoxin b.The oral route of administration is preferred b.Antidiarreals d.Constipation e.Caster oil d.Antitussive i11.Fatigue d.Which of the following action is not seen with sympathomimetics ?i a.Wich of the following cardiac glycosides does not occur naturally ?i a.Pupil constriction b.Propranolol causes rashes and sore throut e.Lack of stability .Senna c.Nausea and vomiting i16-Bacitarcin is not usually given parenterally because of its :i a.Aids to anesthesia e.Various opiates may be used as all of the following except :i a.Which of the following is not a stimulant laxative ?i a.Propranolol is primarily biotransformed in the liver d.i9.Headache c.All of the following are side effects of progestins except :i a.Bisacodyl e.Pantoprazole b.Digitoxin d.Increased heart rate c.Lansoprazole d.Cascara Sagrada b.Systemic blood vessel constriction i13.Analgesics b.Weight gain b.Bronchiole dilation e.Nitroglycerin i10.Omeprazole i15. Lack of potency e.Metolazole i21.| . Indinazir i||.Methionine i22.Bacitracin d.c.Calcium is rapidly excreted b.Each of the following exert antimicrobial action by inhibiting cell wall synthesis except :i a.Excess calcium is not absorbed i23.All of the following are true of haemolytic jaundice except :i a.Cephalosporins b.There is increased production of Bilirubin b.||| only c.Pain at the injection site d.Novobiocin i19.Furosemide b.Calcium is rapidly biotransformed c.Colistin d.Amphotericin B c.Urobilinogin concentration is increased in urine .| and || only d.Vancomycin e.Which of the following drugs should not be administered with high fat meals ?i i|. Stavudine a.Penicillin c.Which is not essential amino acid ?i a.Calcium is insoluble d.Hydrochlorothiazide e.Chlorthalidone c. || and |||i i18.Hypercalcemia does not occur in normal individuals because :i a.Nephrotoxicity i17.Which of the following antibiotics or group of antibiotics does not act by inhibiting of cell membrane function ?i a.Erythromycin b. Riluzole i|||.Polymyxins i20-Which of the following diuretics do not cause potassium loss ?i a.|| and ||| only e.| only b.Nystatin e.Triamterene d.Tryptophane c.Threonine b.Glutamone d. Which of the following beta-adrenergic agents is not short acting ?i a.Erythromycin c.Lethargy e.Terbutaline d. 3 only ic.Alternative Antibiotics for Otitis media for the child allergic to Penicillin include all of the following except :i a.Clindamycin b.The child may be as asymptomatic i28. 1 only ib.Irritability c.Hand tremors b.Bilirubin is found in the urine of the patient e. 2 and 3 i i27.Which of the following Antihypertensive agents has no adverse effect on Glucose tolerance?i i1-metoprolol i2-atenolol i3-captopril ia.Fever b.Which of the following is not useful in the treatment of acute Digoxin toxicity ?i .Possible treatment of Hypoglycemia does not include :i a.Candy c.Trimethoprin – Sulfamethoxazole i29.Production of Urobilinogin is increased d.It is important that the patient recognizes all the following signs as possible Lithium side effects except :i a. 1 .Constipation e.Headaches c. 1 and 2i id.Insulin b.Albuterol e.None of the above i25.None of the above because all are true i24.Mudcle weakness d.Polyuria i30.Glucose d. 2 and 3i ie.Glucagon i26.Pirbuterol b.Signs and symptoms of acute Otitis media do not include :i a.Ciprofloxacin e.Erythromycin – Sulfisoxazole d.Salmetrol c.Stuff neck d.c.Fruit juce e. Some symptoms of iron deficiency include all of the following except :i a.Blurred vision d.Diltiazem i36.Dystrophy of nails d. 1 only ib.Dry mouth i32.Which of the following agents would not be indicated for a patient with angina ?i a.Inderal e. 2 and 3 only ie.In which of the following conditions is iron supplementation indicated ?i i1 Primary hemochromatosis i2 Patient receiving multiple blood transfusions i3 Pregnancy a.Constant thirst c.Ferrous fumarate c.Nifedipine d.Polysaccharide – Iron complex i33.Constipation e. 1 and 2 only id.Ferrous sulphate e.fab fragment antibodies ia.Myalgia.Agitated behavior and ahen pallor .Flecainide c.Ferrous gluconate d. Mydriasis and Nocturia b.Some common patient complaints associated with Anticholinergic drugs include all of the following except :i a.Fatigue b.Which of the following iron preparations is not available oral dosage form ?i a.3 Only c.1 and 2 only d. 2 and 3 i31.lidocaine administration i3.1.Urinary retention b.All of the following may be symptoms of a myocardial infarction except :i a.Isosorbide b. 1 . 3only ic.1 only b.i1.calcium administration i2.Iron dextran b.Shortness of breath c.Dispnea on exertion i35.Dysphagia e. 2 and 3 i34. Which of the following is true about Benzodiazepines ?i a.Patients can develop a psychological dependence b.Chlordiazepoxide i43.Pizotifen (Sanomigran)i c.Flupenthixol b.Can cause tolerance c.Which of the following is not a benzodiazepine ?i a.Pentazocine is more addictive than morphine c. fainting and skipped beats e.Which one of the following statements about chloral hydrate is false ?i a.It is a respiratory stimulant d.Morphine can cause diarhoea i41.Has specific receptors in the GIT d.Clonidine (Dixarit)i i42.May cause vomiting i38.Which one of the following statements about narcotic analgesics is false ?i a.Patients can develop tolerance to the drug d.Patients can develop a withdrawal syndrome c.Clobazem c.All of the following are true about morphine except :i a.Chlormethiazole d.Alprazolam b.Dental and neck pain.Propranolol (Inderal)i b.Dopamine tablets cannot be used to treat Parkinson’s disease because it :i .Which one of the following drugs is not available as antipsychotic depot injection ?i a.May cause diarhoea b.Toxicity is much increased by administration of Ethanol i40.A m etabolite of codeine c. no relief from Nitroglycerin i37.May cause gastritis b.Codeine is useful for its anti tussive properties b.Heartburn.Amitryptyline (Tryptizol)i d.Pentazocine may cause hallucinations d.All of the above i44.c.Which of the following should not be used to prevent migraine in an asthmatic patient ?i a.Chlorpromazine HCL d. sweating and dyspnea d.Fluphenazine c.Haloperidol Decanoate i39.Nausea. Tetracycline hcl d.All of the following are mainly Bacteriostatics except :i a.Clavulanic acid salts b.Is transformed to L-dopa by the autonomic neurons d.Ampicillin d.Sedation d.Gentamycin .Chloramphenicol b.Urinary retention d.Is too toxic after long term administration c.Tetracycline i52.Lamotrigine i47.The following antibiotics are used for treatment of acne in many patients except :i a.Neomycin c.MAOI’s b.Is not m etabolized by mono amine oxidase i45.Barbiturates e.Phenytoin b.Mupirocin c.Erythromycin i50.Constipation i48.Tetracycline i51.All of the following are clinical applications of desmopressin except :i a.The following can be used as topical and systemic Antibacterial preparations except :i a.Sulphadiazine c. b and c i46.Beta blockers d.Does not cross blood brain barrier b.Erythromycin b.Hypotension in the elderly b.Amitryptyline causes all of the following except :i a.Diabetes Insipidus b.a.Nocturnal eneuresis c.Carbamazepine d.Post operative poly urea i49.Which of the following drugs cause insomnia ?i a.Which of the following is not effective for partial seizures ?i a.Ethosuximide c.All of the following have very limited crossing through inflamed meninges except :i a.Penicillin c.Teicoplanin d.Fucidic acid b.Caffeine c.a.Raising of the seizure threshold c.Clindamycin d. The treatment of choice for Kaposi’s sarcoma is which one of the following ?i a.It is converted to triphosphate and subsequently inhibits synthesis of viral DNA c.Temperature and humidity b.Diphenylbutyl piperidines d.Psoriasis c.The following characteristics and uses apply to interferon alpha except for one :i a.Phenalazine c.Dose strength and pack size i56.Mono Amine Oxidase Inhibitor’s include the following except :i a.Butyrophenones b.Lichen simplex chronicus d.Aqueous film coating has the following properties except :i a.Bleomycin b.Benzhexol i59. topical corticosteroids ?i a.Chronic Discoid Lupus Erythematosus b.Thioridazine d.Hygroscopic in nature b.It is a protein b.Water soluble coating d.Tranylcypromine b.Hypertrophic lichen planus i54.It is a hormone i60.It is a nucleoside antiviral drug b.Composition of drug product c.Mitomycin i58.Dactinomycin c.It is an injectable preparation d.All of the following statements of Acyclovir are true except :i a.Moclobemide a-cyproterone acetate b-tamoxifen .Which one of the following is not an indication for potent.It is obtained from lymphoblastoid source c.It is analogue of purine ----bolites d.All of the following drugs are Neuroleptics with the exception of one which is :i a.Trifluoperazine c.Dosage form and packing material d.Doxorubicin d.Stability of pharmaceutical products is affected by the following factors except :i a.Gastric fluid resistant c.i53.Less costly to manufacture i57.It is available topically and orally i55. It is m etabolized in the body to active 6 Mercaptopurine c.It is used to treat body rejection after organ surgical transplant i64.Lithium carbonate i66.It is immunosuppressant b.Chlorpromazine .Competively blocks Angiotensin || at it’s receptors d.Chlorpromazine d.Benzodiazepine d.Nortryptiline d.Benzhexol b.Imipramine HCL i68.Which of the following statements about Naloxone is false ?i a.Wich of the following drugs is not used in the treatment of Parkinson’s disease ?i a.It is a pure antagonist to Morphine b.Captopril and Enalapril do all the following except :i a.Carbidopa i70.Inhibit an enzyme c.Increase rennin concentration in blood b.Which of the following is not used as Antimanic drug ?i a.Corticosteroids d.MAOI’s b.Carbamazepine c.It is used in the treatment of Opiate overdose d.It cause Euphoria c.Excreted unchanged through the lungs and kidneys d.Oxidation b.Amantadine c.Sulphate conjugation i63.m etabolism of ethyl Alcohol involves all the following pathways except :i a.Which of the following drugs is not a Tricyclic Antidepressant?i a.It causes a withdrawal syndrome when given to an opiate dependent subject i67.Which of the following is not cytotic ?i a.Maprotiline c.Which of the following drugs is not classified as Antipsychotic drug ?i a.Raises the blood Potassium concentration i69.Cytotoxic antibiotics c.Trimipramine b.Alkylating drugs b.The following statements apply to Azathioprine except for one :i a.c-flutamide d-triptorelin i62.Conversion to acetaldehyde and acetate c.It is classified as antim etabolite d.Vinca alkaloids i65. 14mg c.6 mg b. The age range for a neonate is considered to be a.08mg/kg/hr.Pimozide c.Risperidone d.126 mg i75.A respiratory depressant c.A package insert lists a drug dose for a neonate as being 10microgram/kg/day.Which of the following statements is false about Amphetamine ?i a.2 mg/kg/ body weigh.It is a controlled drug i72.0.150mg e.8mg i76.58mg b.The infusion of Theophyline established for a neonate is i0.30mg d.Which of the following statements is false about Diamorphine i(Heroin)i?i a.1 year through 5 years i74.Decrease appetite d.Decrease restlessness b.Buspirone i71.Causes nausea and vomiting b.Converted in the body to Atropine i73.Induces hypersensitivity in children c.Blood Pressure measurements were made for 1 week on .72 mg e. What is the appropriate does for a child weighing 60 lb ?i a.The child’s dose of a drug is reported as 1.b. how many ml of drug are needed for one daily bottle if the body weigh is 16 lb?i a.Has potent Atropine like properties d.1 month to 6 months c.Birth to 1 week d.9 mg c.Birth to 1 month b.32 mg d. 80 b.None of the above i79.45% d.express this concentration as a percentage a.05mg of Digoxin per ml.15micrograms b.83 c.30% b. how many micrograms are there in 3 ml of the elixir ?i a.4mg .0006% c.164 i77.160 e.fivepatients with the following averages Patient 1 2 3 4 5 B.84 d.015micrograms c.0.P 140/70 160/84 180/88 190/90 150/70 What is the median systole pressure ?i a.6ppm.57% e.0.00006% b.1.0.A pharmacist add 1 pint of Alcohol USP to 1 L of a mouthwash formula.6% i78. What is the new percentage of alcohol present if original mouthwash was labeled as 12% V/V ?i a.59% i80.5micrograms d.A prescription calls for the dispensing of 4% Pilocar solution with the direction of “ Gtt I OU TID” .0.Lanoxin pediatric elixir contains 0.0.0. How many mg of Pilocarpine HCL is being used per day ? Assume that the dropper is calibrated to deliver i20 drops to the ml a.The concentration of Sodium Fluoride in a community’s drinking water is 0.006% d.38% c.06% e.0. 1/10 c.04ml c.12mg d.8mg e.002ml b.400mg b.1%) may be used to prepare the solution?i a.0. Commercial Clorox contains i5.1/200 Questions 83 and 84 relate to the following hospital formula for a T-A-C solution Cocaine HCL 4% Tetracaine HCL 2% Epinephrine HCL solution 1/2000 Sodium Chloride injection qs 4ml i83.How many ml of Adrenaline Chloride solution (0.The adult intravenous (IV) dose of Zidovudine is 2mg / kg q 4hrs six times a day .25% W/V Sodium Hypochlorate a.1/100 d. How many mg will a 180-lb patient receive daily ?i a-12mg b-164 mg c-650mg d-980 mg e-2160 mg i82.b.160mg i84.4mg c.20mg d.How many mg of Cocaine HCL is in the final solution?i a.1ml d.0.24mg e.1/9 b.6mg c.60mg i81.1/180 e.A pharmacist dilutes 100ml of Clorox with 1 quart of water Express the concentration of Sodium Hypochlorite in the final dilution as a W/V ratio.2ml . 2.5ml i85.100mg c.73 b.60mg b.1.80 c.25microgram/ml i87.80 e.83 d.A pharmacist repackages 10 lb of an ointment in to jars to be labeled 2 oz(with).120mg d.An administration set delivers 60 drops to the ml.100 i89.e.Dopamine (Inotropin) 200mg in 500ml of Normal Saline at 5 microgram/kg/min is ordered for a 155-lb patient.22.240mg i88. what maintenance dose should be administered if the normal maintenance dose is 2mg/lb of the body weight ?i a.88 e.60 d.4micrograms b.40micrograms/ml d.000 units per 250ml of Normal Saline?i a.40 c. How many drops per minute are needed to obtain 20 units of Heparin per minute if the IV admixture contains 15.How many ml of Glycerin would be needed to prepare 1 lb of an ointment containing i5% W/W Glycerin ? (The density of glycerin is 1. How many jars can be filled ?i a.120 i86.2ml b.0. What is the final concentration of solution in micro/ml ?i a.The estimated Creatinine clearance rate for a 120lb patient is i40ml/min.160mg e.2ml c.18.25g/ml)i a.7ml .20 b.5micrograms/ml c.400micrograms/ml e. 0.24ml e. Assume that Radiopharmaceutical follow first t.7.0.545g i91. How many grams of 5% Hydrocortisone ointment could be diluted with White Petrolatum to prepare this order?i a.363g e.4g d.0.18.2g b.0.048/day b.2g b. eq.3.9.28.20g e.A pre------ion calls for 25 m.3 days.25% W/V Acetic Acid ?i a.What is the decay constant (K) of the Radio-Isotope 32P if its half life is 14.How many grams of Glacial Acetic Acid (99. of Potassium Chloride How many grams of KCL (MW 74.186g i94.86g d.6) are needed?i a.000ml c.1/day e.100ml b.746g c.2.d.0.A hospital clinic requests 2 lb of 2% Hydrocortisone ointment.8.95g i92.097/day d.730ml .How many milliliters of a 10% KCL (MW 74.5g c.45.9% W/V) must be added to 1 gal Purified Water to prepare an irrigation solution containing 0.5g c.0.07/day c.15/day i93.12g d.27.1.21.0.6) solution contain 5.86g e.4ml i90.0 mEq of K+ ?i a.46g b.1.order kinetics a. 295g d.00g e.500g b.295.24 grains d.00ml d-16.67ml e-166.010g d.67ml b-18.924 grains e.00ml c-30.924 grains c.150ml d.1050ml c.360 d.Calculate the weight of 25ml of Hydrochloric Acid whose density is 1.2.0.050g i96.600 e.0924 grains i100.The dose of a drug is 0.The dose of a drug is 0.100g e.0.0.None of the above .8g/ml) .950g c. What volume should the pharmacist measure ?i a-1.033g c. What dose should be given to a 6 years old child who weigh 44 lb ?i a.70ml i97.If a pre------ion order requires 30 g of concentrated Sulfuric Acid (density is 1.6mg How many doses are contained in 96mg of the drug ?i a.16 b.0.003g b.0.0.d.0.0.0.Convert 2 pints 3 fluid ounces into ml a.105ml e.5mg/kg.9240 grains b.5ml i99.37.9.300ml e.29.10.1500ml b.160 c.None of the above i98.Convert 60 grams to grains a.18g/ml a.373ml i95. . Gastric acid D. Of tolerance being developed E.Which of the following NSAIDs is available in a parenteral form? A. Of instability C. Glucagon E. Estrogen B.Which of the following are low molecular. Progesterone 6.B and C E.negative bacilli C. Histamine release 7.Rivastigmine has the primary action of inhibiting A. Norepinephrine 5. Epinephrine C.i1. Tinzaparin B. None of the above 4-Nateglinide stimulates the release of A. Gram. 2 to 3 weeks because Of toxicity B. Epinephrine C. HIV virus D. Cortisol E. Piroxicam E.Mifeprostone is a receptor antagonist of which hormone? A. Gram-positive bacilli E. Dalteparin D. Ibuprofen B. None of the above 2. Thyroid C. Insulin D. A.weight heparin? A. They are used longer commonly 3. Gram. Of short duration of need D. Enoxaparin C. Tolmetin D. Glucose D.Linezolid is used against infections caused by antibiotic resistant A. Insulin B.positive cocci B. Acetyl cholinesterase B. Ketorolac C.B and C .Muscle relaxant are seldom used for more Than A. Calcium influx E. By all of the a bove 14-Zonisamide is considered a broad spectrum A. Thiazide diuretic D. NSAID E. Antibiotic B. All of the above 12. Glaucoma B. Tolerance D. Eye cleaners 9.Sucralfate is used for short term theraoy of A. Hypertension C. Obstructive disease of Gl tract D. Headache 13. By injection D.probantheline is contraindicated in patients with A. Rashes B. Anticonvulsant C. Ulcers B. Loop diuretic B. Eye infections E. Atrial tachycardias C. Dibenzazepine E. Antihistamine 15.8. Pink eye C. MAO inhibitor C. Antiviral D. Ulcerative colitis E. Orally B.Antiepileptics as a group are noted for developing or causing A. Polycyclic amine i11.Selenium sulfide is used A. Spasms E.Lorazepam is classified as A. Glaucoma B. Carcinomas D. Topically C. Calcium depletion E.Baclofen is used primarily as a(an) .Ocular timolo is used primary in A. By none of the a bove E. Dental caries 10. Myasthenia gravis C. conjunctivitis D. Ofloxacin is classified as a (an) A. Antidepressant 19.Mirtazapine is used to treat symptoms of A. Antirickettsial . Antianxiety agent C. Adult. Muscular spasm 18. cardiac insufficiency D. Antifungal B. Antiviral C.candassartan is used as a(an) A. Antihypertensive C. Gout D. Antispasmodic E.onset diabetes B. Acidosis D. Narrow spectrum antibiotic E. Hypertension C.A. Sedative E. 1.11and111 20. None of the above i21. 1only G.11only H. A prevalent side effect of propylthiouracil is A.Beta interferon is used to treat A. Hypnotic D.Analgesic properties 111. Muscle relaxant D. Leukopenia E. Depression B. Broad-spectrum antibiotic D.1and11only I. 11and111only J. Diuretic B. Tranquilizer 16. Ulcers 17-. Visual impairment C. Sympathomimetic B.Anti-inflammatory properties 11. Petit mal epilepsy E.the pharmacologic actions of sulindac include 1.Antipyretic properties F. Multiple sclerosis E. Hearing loss B. Parkinsonism C. Hyperactivity D. Vasoconstriction B.Zidovudine may commonly cause which of The following as a side effect? A. Sodium nitorprusside B. Hirsutism C.Mupicorin ointment is used topically to treat A. Visual problems E.Estrogen tend to increase the risk of A. Endometrial carcinoma B.Allopurinol differs from most other agents used to treat gouty conditions because A. Chlorothiazide D. Hearing loss D. pregnancy 28.Pentoxifylline acts primarily by A. All types of eye infections C. Serpasil C. Conjunctivitis B. Dissolving cholesterol B. Organic nitrates . Triamterene 26. Anuria 23. Increasing biotransformation D. Has analgesic properties 27.22. Fluroquinolones B. Does not decrease uric acid levels B. Decreasing viscosity of the blood C. Causes rapid biotransformation of uric acid E. Anemia E. Dryness of the mouth C. Impetigo D. Increase elimination of uric acid D. Preventing formation of cholesterol 25. Hemorrhoids 24. Prevents formation of uric acid C. Oxidative mechanisms E. Spironolactone E. Carcinomas of the skin E.Which of the following drugs is contraindicated when used with sildenafil? A.Which of the following is most useful in treating hypertensive crisis? A. Burns C.Risendronate is classified as a (an) A. Fatigue B. Calcium channel blockers E.Gentamicin exhibits A. Amphotericin . Propionic acid C.C. Diuretic D. Significant dermal toxicity D.Carbamazepine is used as an anticonvulsant as well as to treat pain from A.Doxorubicin is used to treat A. All of the above 30. none of the above 29. Hyperkinesis disorders C. Bisphosphonate C. Carcinomas 34. Viral infections E.Methylphenidate is used to treat A.A drug is useful in treating potentially fatal fungal infections is A. Muscle injuries D. Gram. Nystatin B. A wide variety of infections B. Gram. Anxiety D.negative infections D. Significant nephrotoxicity E. Immunosuppressant E. Obesity 33. Depression E. Cardio suppressant B.positive infections C. Sympathomimetic i31. Significant cardiotoxicity C. Penicillins D. Sinus headache E. Kidney infections B. Trigeminal neuralgia 32. Significant hepatotoxicity B. Narrow angle glaucoma B.Which of the following drugs is not a proton pump inhibitor? A. Produces very little depression of the CNS E.Antimuscarinic drugs are contraindicated in A. Is twice as affective B.Nonselective 2. RabeprazolE C. Peripheral vascular disorder B. Pantoprazole B. Treatment of influenza B infection C. Unjustified C. Widely accepted B. Has better analgesic properties 37. Is more stable C. A and B E. Prophylaxis of influenza infections D. Treatment of influenza A infection B. Migraine headache D. Acceptable if the patient is closely monitored 36. Atherosclerosis E. Tachycardia C. A. Pyloric or intestinal obstruction D. Acceptable in combination with other drugs D. Renal insufficiency 38. Paralytic ilens C. Nystatin E.An advantage of dextromethorphan ove codeine as an antitussive is that it A. B and C 39.adrenoreceptor antagonists are used primarily in A. A. Griseofulvin 35. Only acceptable if other treatments fail E. Has no side effects D.Zanamivir and ostelamivir are both FDA approved for A. A and B E. Lansoprazole .D. B and C 40.The use of thyroid hormones in the treatment of obesity is A. Dissolve blood clots B. Treat digestive disorders . Causes hypertension E.Lumivudine is usually classified as a(an) A. Anthelmintic 45. H2 antagonist B. Ulcer protectant C. Arsenic trioxide C. Sulfisoxazole E. May lose its effects 43.A danger of prolonged use of pilocarpine salta as a miotic is A.D. Conjunctivitis D.Streptokinase is used to A.Which of the following drugs require electrocardiographic monitorizing Prior to infection of therapy? A. Tearning B. Antiviral D. Anuria C. Causes arterial blockade C. Persistent headache 46. Ziprasidone B. Ulcers B. Oral antidiabetic E. Omeprazole i41.Prolonged usages of sublingual nitrates is likely to cause A. Interact with digitalis glycosides B. Rashes D. Detached retina E. Lens opacity 42.B and C E 44. May cause anuria D. Cisapride D.A serious side effect of furosemide in treating heart patients is that it A. A and B A. Glaucoma C. Development of tolerance E. None of the above i51. Releasing histamine C.A drug is used to treat delirium tremens is A. Testosterone E.Tamoxifen is classified as a(an) A.Cromolyn sodium acts by A. Androsterone D. Ulcers C. Analgesia B. Niacin E. Estrogen B. Kidny failure D. Thiamine C. Antipyretic effect . Vitamin C D.C. Treat muscle injuries E. Disulfiram D. Haloperidol C. Promote carbohydrate degradation D.The anti-infammatory action of aspirin is due to A. Replace pepsin 47. Psoriasis 48. Vitamin D B. Methadone E. Riboflavin 50. Chlordiazepoxide B. Preventing the release of histamine E. Rheumatoid arthritis E. Inhibition of clotting C. Biotransforming histamine D. None of the above 52.Gold compounds have been used to teat A. Thyroid hormone 49-Beriberi is associated whith a deficiency of A. Antiestrogen C. Destroying histamine B. Worm infestations B. Aprevalent side effect of norethindrone is ِِِ A. Parkinsonism B. Periodontitis B. Diarrhea B. Gentamicin D. Stool softening E. Lyme disease E. Degradation of prostaglandins E.Penicillamine is most commonly used to treat A. A. Capecitabine C. Dexfenfluramine D. Astemizole 56. Wilson's disease C. Breakthrough bleeding C. B and C 58. Famotidine B. Acne D.Which of the following drugs requires a dosage adjustment in patients with renal impairment? A.Doxycycline oral gel is used to treat A. Inhibition of prostaglandins synthesis 53. A and C E. Bulk producing 54. Raynaud's disease E. Terfenadine E.D. Neoplasms D. Lubricating B. Aphthous ulcers C. Gram.Castor oil is classified as which type of laxative? A. Arthritis 57. Anthraquinone C.positive infections 55. Cerevastatin B.Which of the following durg are withdrawn from the US market In 2001 due to increased risk of myopathy and rhabdomyolysis? A. Blood dyscrasiency . Cisapride C. Irritant D. the preferred way to offset hypokalemia is to A. I. Meperidine II. II and III 62. salicylate analgesics i61. II and III only E. I only B.Flumazenal is a specific antagonist for which of the following drugs? I. Carbohydrates C. Haloperidol . Ketoconazole III. Administer potassium salt D. Fats and lipids D. Abortion 59.Which of the following drug's may inhibit the m etabolism of ziprasidone? I. I only B. Propoxyphene III.Which of the following antidepressant also had an indication for smoking cessation? A. Eat citrus fruit B. Erythromycin II. I and II only D.D. I and II only D. Phenobarbital A. Diazepam A. Cardiac insufficiency E. I. Some fermented and beverages B. Dimnish urination 60. Eat sea food or fish C. Water E. III only C. II only C. II and III only E.Persons receiving MAO inhibitors should control their intake of A. II and III 63. Administer IV electrolytes E. Nonnarcotic analgesic C. Mirtazapine E. I and II only D. I and II only D. Bupropion C.inflammatory D. Transdermal patch A. III only C. Take with 6 to 8 ounces of plain water III. I only B. Ointments II. II and III only E. Doconasol D. Antiviral E. III only C. I. II and III only E. Riluzole E. Pioglitazone C.Which of the following statements is true regarding the Administration of alendronate? I.Testosterone is available as which of the following dosage form? I. Take more than 30 minutes before first food or beverage of the day II.Which of the following is an oral hypoglycemic agent? A. Injection III. Diuretic B.B. I. Remain fully upright ( sitting or standing ) for about 30 minutes A. Terbinafine 68. Ketorolac B. I only B.Docosanol is a (an) A.The concurrent administration (within 1 to 2 hours of dosing) of . Anti. Paroxetine 64. II and III 67. Citalopram D. Anthelmintic 65. II and III 66. II and III 69. Grapefruit juice III. Hepaic impairment i71. 10 minutes 72. I and II only D. II and III only E. Tremor III. III only . Cardiac valvular dysfunction B. II and III 70.Which of the following drugs may be administered without regard to meals? I. I only B. Ototoxicity E.The terminal half _ life of alendronate is A. Cetirizine III. Gastric ulcerations C.Dexfenfluramine. I only B. I. III only C. 10 hours E. II only C. Acarbose A. High _ fat meal II. I. 10 months C. Cocoa A. Renal toxicity D. 10 years D. Mental states changes II. was removed from the U.Serotonin syndrome is characterized by which of the following syndrome? I. I and II only D. II and III only E. I only B. an agent approved for the treatment of obesity .nislopidine should be avoided wih which of the following? I.S market due to A. Diaphoresis A. 10 days B. Valaciclovir II. I. Respiration A. Psedoephedrine C. Sleep ll. Circadian lll. l . Toradol . Skin grafts E. I and II only D. l and ll only D. Aluminum hydroxide ll. Oxy contin B. ll and lll only E. l only B. l.Tacrolimus oin tment is used primarily to treat A. ll and lll 76.Which of the following antacids should not be used in dialysis patients? l. Which analgesic experienced significant misuses and diversion.the FDA has recommended the removal of which ingredient found in cough/cold products due to an association with hemorrhagic strke? A. l only B. ll only C.C.ll and lll 75. II and III 73. Sunburns D. ll and lll only E. Poison ivy 77. requiring revisions in the warning section of the product labeling? A. Ephedrine 74.Calcium carbonate A. Tylenol #3 D.Melatonin reg ulates which of the following functions? l. Pain B. Guanfenisen D. II and III only E. Demerol C. Atopic dermatitis C. Dextromethorphan B.In 2001 . l and lll only D. ll only C. Phenylpropanolamine E. Magnnesium hydroxide lll. Histamine 2 ahonist 82. ll and lll only E. Blocking dopamine D.Ocular timolol is used primarily to treat A. ll only C.Bivalirudin is a (an) A. Histamine 2 antagonist D. Omeprazole/ clarithromycin lll. None of the above 81i. l and ll only D. Histamine 1 agonist E. l only B. Nonspecific histamine antagonist B. None of the above 80. exerts its pharmacological effects by A. Inhibiting histamine reuptake B. Anti. Glaucoma C.Which of the following drug combination has (have) been effective therapy for the treatment of Helicobacter pylori? l. Clarithromycin/ ranitidine bismuth citrate ll. Histamine 1 antagonist C. Ciprofloxacin/ erythromycin A.infective C. NSAID D. Stimulating serotonin synthesis C.Cetirizine is a A.ll and lll 79.Antihistamine . an agent used to treat schizophrenia . Cataracts D. l .Ziprasiodne . roxanol 78. Stimulating dopamine release E.E. Anticoagulant B. Antiviral E. Conjunctivitis E. Mydriasis B. Tinnitus 88. Hematologic B. Eczema 84.The principal adverse effect of acarbose is A. l and ll only D. Xerostomia C. l .83. ermal 87. ll only C. Monitoring serum phenytion leveis is not necessary A. Renal D. ll and lll 86. Dermatitis B. Allergic rhinitis D.Which of the following statements regarding fosphenytoin are true? l. l only B.Crotalide is used to treat the bites of A. Tinea versicolor E. Gastrointestinal C.Oral parenteral ketorolac therapy is limited to 5 days of therapy due .Cevimeline is used to treat A. North American vipers C. Rabid animals E. Fleas B. Ticks D. Fosphenytoin is completely converted to phenytion after intravenous or I ntramuscular administration ll. Ovarian cancer B.Unoprostone is FDA approved to treat A. ll and lll only E. Hepatic E. Open angel glaucoma D. D. The administration of 1 mmol of phenytion 111. Hodgkin's disease C. Conjunctivitis E. Black widow spiders 85. Fluvastatin E. Potassium depletion C.Diuretics tend to enhance lithium salt toxicity due to A. Taking phenelzine lll. With uncontrolled hypertension A. Simvastatin B. CNS disturbances E. ll and lll only E. With a body mass index greater than 30 kg/m2 ll. l only B. Renal impairment B.to an increased risk of A. With poorly controlled hypertension A. Psoriasis D. Increased absorption E. l only B. lll only . Crohn's disease B. l and ll only D. Taking MAO inhibitors lll. Rheumatoid arthritis C. None of the above 93. With a history of ischemic heart disease ll. All produce *****alent reductions 90. Liver failure D. Sodium depletion B. lll only C.Sibutramine should not be used in patients l. Photoallergic reactions E. Lovastatin D. l . A and B 89.Which of the following HMG-CoA reductase inhibitors causes the greatest percentage increase in HDL? A. ll and lll i91.Sumatriptan use is contraindicated in patients l. Gastro intestinal bleeding/ perforation C. Direct drug interaction D.Leflunamide is used to treat A. Pravastatin C. Increased solubility of the lithium salts 92. Methylphenidate lll.Which of the following agents are approved for treatment of narcolepsy? l. Glycoprotein llb/ llla receptor inhibitor C.ll and lll 94.C. Fluoroquinolone B.Treat Paget's disease 99..Eptifibatide is classifided as a (an) A. lll only C. None of the above 95. Nalmefene B.A useful agent in the treatment of bladder incontinence is A. Valrubicin E.CoA reductase inhibitor B.l and ll only D. Prevent osteoporosis D. Tolcapone D. Prevent renal toxicity E. Dextroamphetamine A. tolterodone C. Diuretic D. l . P450 hepatic enzyme inhibitor E.Increased insulin secretion B. l only B.Finasteride's action in the treatment of benign prostatic hypertrophy is a (an) A. l .Misoprostol is used to A. Antihypertensive E. exerts which of the following mechanisms of action? A. Modafinil ll. Serotonin reuptake inhibitor D. Increased insulin receptor sensitivity . l and ll only D. ll and lll only E. Prevent NSAID-induced gastric ulcers C.None of the above 97. Alpha-5reductase inhibitor C. ll and lll 98. None of the above 96. HMG. a hypoglycemic agent.Acarbose . ll and lll only E. Treat gastric ulcers B. Ciprofloxacin C.Which of the following drugs interferes with the m etabolism of indinavir? A. Ketoconazole B. None of the above 100. Delays digestion of carbohydrates E. None of the above . Decreases circulating insulin antibiotics D. Digoxin D. Lorazepam E.C . Acid phosphatase d.A source of anticarcinogenic drugs is a.Is independent of temperature c.Sigmoid colon i6.Prostaglandins b.Urogenital sinus i4.Transvers colon c.Prostate and anus b.Prostate and bladder i2.Illeal d.Clitoris develops from a.i1.Belladona b.The rate of zero-order reactions a.Digitalis .Descending colon d.Seminal vesicles are present between a.Holds only for light catalyzed reaction e.Inhibin c.All of the above i3.Lipid solubility b.Pelvic i5.Genital tubercle b.Retroceacal c.Genital ridge c.The shortest part of the colon is a.Changes constantly b.Molecular size e.Cascara e.Polarity d.Ascending colon b.Prostate and rectum c.Vinca rosea d.Mullerian duct d.Plasma protein binding c.All of the above i7.is independent of concentration d.Nux vomica c.Holds only for radio active compounds i8.Bladder and rectum d.Which of the following factors affect the distribution of a drug?i a.Commonest anatomical site of appendix is a.Paraceacal b.Seminal vesicles secrete a. Dicumarol .Dextrose b.Reduction i12.The buffer equation is also known as a.Cacium salts e.i9.If a central nervous system (cns) drug is extensively ionized at the ph of blood it will a.Be eliminated slowly e.Most drugs are a.Powdered sucrose i15.Charles equation c.Penetrate the blood – brain barrier slowly b.Not to be distributed to any tissue sites i10.None of the above i13.Non electrolytes d.Zero order rate d.Bal c.An antidote for heparin overdose is a.Weak electrolytes c.penetrate the blood – brain barrier rapidly c.Henderson-hasselbalch equation d.Not penetrate the blood – brain barrier d.The major mechanism of degradation of drugs in the gut is a.Conjugation e.Atropine d.First order rate e.Strokes’ law e.Lactose c.Fractional order rate c.Potassium bitartrate e.Second order rate i14.Radioactive decay follows a a.Hydrolysis c.Oxidation b.Acetylation d.Mixed order b.Highly ionic e.Strong electrolytes b.The most common disintegrator in compressed tablets is a.Starch d.Protamine sulphate b.None of the above i11.Young’s equation b. pressure filtration b. Only b.Iron d.Bulk powders j.|| and ||| only e.Starch is used in tabletting as a i|. Protective barriers i|||.Keratolytic agent i17.All of the above i22.sublimation c.| and || only d. Only c. || and |||i i21.Cobalt e.Ointments are typically used as i|. Emollients i||.Surface evaporation d. Binder i||. Vehicles for applying drugs a.freeze dying is based on a.|.i16.A humectant retards a.Divided powders i20.pasteurization e.|||.Salicylic acid is used primarily as an (a)i a.Analgesic b.|.Nickel c.Antipyretic c.Uricosuric agent e.Hard capsules g. Disintegrant .Which of the following is found in vitamin b12?i a.polymerization d.Cough suppressant d. Glidant i|||.Bacterial growth b.Soft gelatin capsules h.Magnesium b.Degradation c.Tablets i.densification i19-the most prevalent commercial solid dosage forms are f.Spreadability e.Manganese i18. W/o bases i25. Only b.Glidants c.Water-soluble bases d. || and |||i i23.Syrup nf is a.High temperature c.The dea d.|||. Only c.Micelle c.Gmp regulations are promulgated and revised by a.flavored and preserved i26.|.Absorption bases c.Amino acid .Both b and c i24.Lubricants d.a.State boards of pharmacy c.Freezing d.Emulsion d.A supersaturated solution c.The fda e.|| and ||| only e.Photolysis e.Binding agents e.A dilute solution d.Disintegrators b.Vanishing creams are classified as a.high unstable e.Ferritin is a (an)i a.Congress b.The epa i28.Vitamin b.Reaction rate is increased most rapidly by a.O/w bases e.||.Humidity b.Self preserving b.Hydrolysis i27.Oleaginous b.Gums are used in tabletting primarily as a.| and || only d. And ||| only e.Thiamine hydrochloride e.Applied 2 hrs before exposure c.Hydrophobic action b. And ||. Only d.Sunscreen preparations containing p aminobenzoic acid should be a.Vitamin d b.Niacin c.Enteric coating material c.Used only on arrears other than the face i31. Only c.Emulsifier b.Tribasic cations d.Cellulose acetate phthalate is used in pharmacy as a (an)i a.Riboflavin c.Bismuth subsalicylate is used in antidiarrheals for its a.||.i29. It may cause irritation and sensitization i|||.|.Which of the following is classified as fat soluble?i a. It is most fungistatic of the fatty acids a.Niacin d.Antibacterial action i35.Adsorbent action d.Suspending agent .The active constituents of saline laxatives are a.Used sparingly b.|||.Packaged in light-resistant containers e. || and |||i i32. It is often used as zinc salt i||.Hydrophilic action c.|.Absorbable cations and anions e.Cyanocobalamine i30.|.Nonabsorbable anions c.Nonabsorbable cations and anions i34.Packaged in air-resistant containers d.Thiamine b.Ascorbic acid d.Absorbable anions b.Absorbent action e. Only b.Which of the following statements is (are) true for undecylenic acid?i i|.Pyridoxine e.Vitamin b6 is also known as a.Riboflavin i33. Reagent for absorption of carbon dioxide e.Which of the following is associated with excessive infusion of hypotonic fluids?i a. Buffering a.Melting point c.Preservative in aromatic waters i40.||. Isotonicity i|||.The most widely used method for sterilization of pharmaceutical is a. Sterility i||.d.Moist heat e.The limulus test is relatively new method of testing for a.Flavoring agents e. And |||.Creaming e.||.Ethylene oxide exposure d.Stabilizer in emulsions d.|.Dehydration d.Glycosuria e.Hemolysis b.Solubility b.Excipient i36.Alkalinizer b.Microfiltration b.Ophthalmic solutions should be formulated to include which of the folloeing?i i|.Lipophilic properties i37. Only c.Coca butter (theobroma oil) is used as a suppository base because of its a.Reactivity e.Therapeutic agent in topical preparations c.Miscibility d.|. Only b.None of the above .Lack of osmolarity i41.Dry heat i38. || and |||i i39.Radiation c.Acidity d.|.Pyrogens b.Soda lime is used as a (an)i a. And || only d.Microbial growth c.Hyperglycemia c. Only e. Normal rectal temperature is usually a.Hydrocortisone c.Before meals c.Hyperglycemia c.Right ear i45.After meals b. Only b. And ||.All of the above i43.The principal use of magnesium stearate in pharmaceutics is as a(an)i .Measured in the morning b.About 1c lower than oral e.Measured in the evening c.Glycosuria e.Each ear e. Greater accuracy of dosing a. Enhanced stability i||.On the empty stomach i47.Loss of electrolytes b.|.i42. || and |||i i46.Cortisone b.Dexamethasone i48.Without meals e.The latin post cibos can be translated to mean a.|||.The latin oculo utro is translated to mean a.With meals d.Each eye c.Advantages of tablets over liquid dose forms include the following i|.Dehydration d.|| and ||| only e. Only d.Prednisone is converted to which of the following by the liver?i a. Only c.|.Prednisolone d.Methylprednisolone e.About 1c higher than oral i44.About same as the normal oral temperature d.Which of the following is associated with excessive infusion of hypertonic dextrose?i a. Ease of administration i|||.||.Right eye b.Left eye d. Indanediones e.The major use of titanium dioxide in pharmacy is in a.Lente c.Antacid c.Disintegrator e.Mix gently by rolling between palms of hands c.Regular e.The recommended method of mixing insulins is to a.Sunscreens b.a.Right eye b.Oxycel c.Source of mg ion d.Right ear i54.Antacid tablets c.Stabilizing i50.None of the above i52.Emulsions i51.Lubricant b.Absorptive d.Effervescent salts e.Activated charcoal is used in some antidotes because of which of its properties?i a.Which of the following is used as a hemostatic agent?i a.Heparin b.Shake vigorously b.An other name of extended insulin zinc suspension is a.Both eyes e.Coumadins d.Ultralente d.Add simultaneously to container d.Nph b.Neutralizing b.Emetic c.Binder i49.Both ears d.The latin oculus sinister means a.Add lente insulin first then regular insulin e.None of the above .Left eye c.Adsorptive e.Capsules as a diluent d.None of the above i53. paralysis of spinal chord C.Propranolol d.Acetaminophen e.The formulation of different active ingredients that have been judged to produce similar effects are called i|.Phenytoin c.i55.too much levodopa in the brain E.Skin thickness is not a factor in drug absorption c. And || only D-|.too much dopamine in the brain i60-the greatest threat from the morphine poisoning is A. Generic *****alence i||. Pharmaceutical *****alence A-|. Only C-|.The transdermal unit may remain attached to the skin after the labeled delivery period because drug absorption cases i57-dosage of anticonvulsants is adjusted A-when seizures occur frequently B-every 2 weeks C-every 2 years D.only when side effects are seen E-seasonally i58-which of the following agents is associated with tinnitus as a result of toxicity?i a.The transdermal unit contains more drug than is needed for delivery into the bodyover the prescribed the period of use e.too little dopamine in the brain B.respiratory depression . || and |||i i56. Only B-||.renal shutdown B.Products from different manufactures require identical amounts of the active ingredient to yield *****alent responses b.Cyclobenzaprine i59-parkinson is probably due to A.Salicylate b.too little acetylcholine in the brain D.The transdermal unit should always be placed at the same site d. Therapeutic *****alence i|||.too little levodopa in the brain C.Which of the following is a true statement regarding transdermal delivery systems?i a. magnesium ion is necessary in A.nerve conduction D.meprobamate i62.ergot alkaloids E.stramonium alkaloids D.cyclosporine is used for A.angina C.polybrene C.nalorphine D-universal antidote E.trimethoprim C.cardiovascular collapse E.all of the above E.furosemide i63-wich of the following is used to lower blood lipid levels?i A.colesevelam C-flucytosine D-coumarin E.allopurinol B.vinic al kaloids B-digitalis C.prevention of transplant rejection .muscular contractions C.a class of plant alkaloids widely used to treat migraine is A.congestive heart failure i65.D.mehtenamine D-ethacrynic acid E.muscular injuries C.none of the above i66.capecitabine is used to treat A.hypertension B.propranolol i64.ulcers D.trimethadione B.breast cancer E.stimulating enzyme systems B.none of the above i61.wich of the following is used to curtail chronic uric acid stone formation?i A.belladonna alkaloids i67.meperidine B.a specific narcotic antagonist is A.allergies B. is not destroyed by pencillinase C.D-steroids deficiency E.cleft palate i73.colitis D.limb deformations E.spina bifida B.gastric hyperacidity B.does not cause allergies E.hypertension C-cardiac insufficiency D.is more acid stable B.a and c E.nasal drops C.diuretic B.ulcers B.migraine headache i69.has a longer ----f of life .cystic fibrosis C.treating lead poisoning i68-pantoprazole is used primarilt to treat A.antidepressant D-anti-inflammatory E.patent ductus arteriosus D.gout E.a.an advantage of amoxicillin over ampicillin is that it A. b and c i72-folic acid administration has been recommended during pregnancy to prevent which of the following congenital problems?i A.in which of the following dosage is nicotine available when used as smoking detergent?i A.cardiac toxicity C.anthelmintic i70.has a broad spectrum D.cardiotonic C.daunorubicin and doxorubicin have been commonly associated with A.gum D.citalopram is a(an)i A.transdermal B.gout E-hepatotoxicity i71. reduction of anxiety D.Causing intoxication d. is m etabolized to a. a 5-ht3 antagonist is an(a)i a.Metformin d.Diuretic b.Neuralgias e.Parkinson's disease d.blood clotting E.Sunscreen i78-cholestyramine resin has the prevalent side effect of a.All of the above i79.Raising cholesterol levels c.sedation B.Timolide combines the action of nonselective beta blocking agent and a(an)i a.none of the above i80.lorazepam produces which of the following action(s)?i A.B.duodenal ulcers D.Cardiotonic .adrenergic blocker b.Arsenic trioxide was approved by the fda in 2000 to treat which of the following disease?i a.Increasing sensitivity to uv light e. used in the treatment of generalized tonic-clonic seizures .all of the above E.Antiemetic c.gout C.Phenytoin b.none of the above i77-dolasetron.Colon cancer i75.None of the above i76-vincristine has been commonly associated with which of the following adverse events?i A.Primidone.Muscle spasms c.loss of memory C.Leukemia b.Carbamazepine e.Glucocorticoid d.i74.Local anesthetic e.Blocking absorption of some vitamins b.Phenobarbital c.neurotoxicity B. carbamazepine.Preanesthetic agents i83.Oral contraceptives c..Anti-inflammatory agent e.Tranquilizer d.Muscle relaxant b.Ibuprofen d.All of the above i85.Nausea .Aspirin b.Treating carcinomas d.Sedatives b.Hypnotics c. gabapentin) are fda approved to treat seizures but have also been effective in the treatment of a.Phenobarbital i82.Diagnostic testing e.Selective beta blocker d.Naproxen e.Colitis d.Analgesic e.g.Nausea e.Abortifacients i84.Which of the following drugs has been associated with reye's syndrome in children?i a.Sedative hypnotic c.Severe pain e.Heparin-induced thrombocytopenia d.Vasoconstrictor i81.Ultra-short acting barbiturates are used primarily as a.Antispasmodic agents d.Efavirenz is classified as a(an)i a. phenytoin.c.Acetaminophen c.Antiviral i86.Lepirudin is used mainly to treat a.Anti-parkinsonian agents e.Minor anxiety states c.Norethindrone is a drug commonly used in a.Mixed estrogens b.Some anti-convulsant (e.Gastritis b.Neuralgias or neuropathies c.Parkinsonism b. Cerebrum b.The mucosal layer of the gi tract c.Myocardial infarction c.A and b e.Orlistat is used as a(an)i a.None of the above i92.Im c.Albiterol is usually administered by which route?i a.Antipruritic c.Prostate cancer e.Tenecteplase is used primarily to reduce mortality associated with which of the following clinical problems?i a.Oral .Hemorrhage d.Iv b.Nerve endings i90.More stable than most local anesthetics b.Weight loss agent d.i87.Antipsychotics usually act on the a.Anesthetic i89.Diabetes b.A.Brain and spinal chord e.Antiepileptic e.The granules of mast cells in the blood b.Cerebellum c.Nasal d.Histamine is found in the human body in a.Antiarrhythmic e.Cocaine has a long duration of local anesthetic action because it is a.General anesthetic b.Not biotransformed d.Analgesic i91.Narcotic antagonist b. b and c i88.Narcotic analgesic c.None of the above i93.A vasoconstrictor e.Rectal e.Preanesthetic d.Lower brain areas d.Readily absorbed c.Lidocaine is used as a local anesthetic or as a(an)i a.The hypothalamus d. Nateglinide is used most commonly to treat a.Alkaline d.i94.Aids b.Angina c.Barbiturates.Poor oral absorption i96.Acid i97.Genital herpes c.Nitroglucerin has a relatively short-half life due to a.Depression i98.Calcium channel blocker e.Instability d.Meloxicam exerts its action because it is a(an)i a.Influenza i95.Bethanecol e.Lack of habituation b.Atropine d.Nonsteroidal anti-inflammatory b.Its poor absorption d.Neostigmine c.Glaucoma e-Muscle spasms .Oxcarbazepine is used to treat a. are particularly noted for a.Cmv retinitis e.Producing microsomal enzymes in liver c. in general.All of the above i100.Acetylcholine b.Trihexylphenidyl is used to treat a.Its volatility b.Parkinsonism b.Methacholine i99.Mao inhibitor c.Angina pectoris d.Diabetes d.Partial seizures b.First-pass metabolism e.Slow absorption e.Its chemical instability c.Hdogkin's disease c.Breast cancer e.Which of the following is classified as a cholinergic antagonist?i a.Xerostomia d. . i1.Methylcellulose and similar agents are in ophthalmic solutions to A) Increase drop size B) Reduce drops size C) Increase ocular contact time D) Reduce tear formation during instillation of the drops i6.0 D) 8.life A) Tolbutamide B) Glibenclamide C) Tolzamide D) Chlorpropamide i7.The highest concentration of benzoyl peroxide for acne to be sold as OTC in the UAE is A) 2.Which of the following should NOT be administered to a patient being treated for narrow.0 i3.0% C)10% D)15% i2.0 to 10.angle glaucoma EXCEPT A) Carbachole B) Atropine C) Dipivefrine D) Betaxolol i5.Which of the following sulfonylureas has the longest half.0 to 6.All of the following drugs are used to treat patients with open.The insulin preparation which is non.5% B) 5.0 to 3.0 B) 4.The appropriate PH range for aphthalmic products is A) 2.immunogenic A) Protamine zinc insulin suspension B) Human insulin C) Bovine insulin D) All of the above .0 C) 6.0 to 8.angle glaucoma A) Dipivefrine B)Pilocarpine C) Carbachol D) Homatropine i4. oestrogens act to.Side effects of isotretinoin (Roaccutane) include A) Dermatological reactions B) Depresion C) Teratogenicity D) All of the above i12.Lidocain Hcl is NOT administered orally because it is A) ineffective by this route B) Too acidic C) Too acidic by this rout D) A cause of arrhythmias i13.Which of the following is the shortest acting Mydriatic A) Atropine B) Pilocarpine C) Tropicamide D) a.Which of the following substances when present inurine is the most likely positive sign of pregnancy A) Thyroid stimulating hormone B) Melatonin C) Human chrionic gonadotropin D) Corticotropin i10.Calcitonin is produced in the A) adrenal cortex B) Thyroid gland C) Pancreas D) Adrenal medulla i14.Incombined oral contraceptives. b and c . A) Inhibit of leuteinising Hormone B) Inhibit release of Follicle stimulating hormone C) Inhibit ovulation D) Cause thickening of cervical mucus i9.Which of the following is NOT secreted by the pituitary gland A) Somatotropin B) Human chorionic gonadotropin C) Follicle stimulating hormone D) CRH i11.i8. Which of the following is a blood platelet adhesion inhibitor A) Dipyridamole B) Nitrafuratoin C) Dextropropoxyphene D) Imipramine .i15.Which of the following is the first diagnostic symptom of digoxin overdose A) Anorexia.Prolactin inhibiting factor is A) Dopamine B) Thyrotropin C) Somatotropin D) Corticotropin i17.positive bacterium D) None of the above i16.Tinea infections are caused by A) Virus B) Fungus C) Gram.The action of Digoxin is enhanced by a high level of which of the following ion A) Sodium B) Calcium C) Magnessium D) Potassium i19.Which of the following drugs is NOT associated with increased prolactin secretion A) Chlorpromazine B) Metocloproamide C) Bromocryptin D) Methyldopa i18. vomiting B) Constipation C) High bodytemperature D) Bronchospasm i20. nausea. availability because A) Its chemically unstable B) Its poorly absorbed C) It has a first pass m etabolism D) a. Metronidazole i27. Clarithromycin B) Tetracycline. pylori contains A) Amoxycillin.i21.Which of the following is most useful in treating hypertensive crisis A) Chlorthiazide B) Spironolactone C) Sodium Nitroprusside D) Adenosine i26.A triple therapy for erapy for eradication of H.Pentoxifylline acts primarily by A) Dissolving cholesterol B) Decreasing viscosity of the blood C) Oxidative mechanisms D) Preventing formation of cholesterol i25. Omeprazole.Nitroglycerin has a relatively low bio. Clarithromycin.Lidocaine is used as A) General anaesthesia . Amoxycillin.Methyldopa is used as a /an A) Antiparkinsonism B) Sedative C) Antihypertensive D) Prolactin inhibitor i24. Clarithromycin C) Vancomycin. Metronidazole D) Pencillin.b and c i22.Sucralfate is used to treat A) Peptic ulcers B) Carcinoma C) Calcium depletion D) Obesity i23. Amoxycillin. The principal toxic effect of A) Bronchospasm B) Chillis C) Hair loss D) Haemorrhage i29.Which of the following is a lipid lowering drug A) Aprotinin B) Tranexamic acid C) Lansoprazole D) Gemifibrozal i31.B) Antipruritic C) Antiarrythmic D) Preanaesthetic i28.Which of the following side effects will be caused by antacids containing sodium bicarbonate A) Belching B) Constipation C) Diarrhoea D) Blurred vision i33-Which of the following is a dopamine antagonist A) Grannisteron B) Domperidone C) Cisapride .Simethicone is a\an A) Antacid B) Antiflatulent C) Constipating agent D) Laxative i32.Which of the following is NOT true about Misoprostol A) It's a prostaglandin analogue B) It is used to prevent NSAID'S induced peptic ulcer C) It may be used in pregnant women D) It causes diarrhea i30. Which of the following drugs is the choice for the treatment of all forms of Schistosomiasis A) Praziquantel B) Mebendazole C) Niclosamide D) Thiabendazole i37.Which of the following drugs is a systemic amoebicide A) Diloxamide furoate B) Pyrimethamine C) Emetin D) Sodium stibogluconate i35. coli D) UTI due to pseudomonas aeruginosa i40.In Which of the following infections ciprofloxacillin is least effective A) UTI due to a beta.D) Loperamide i34.Which of the following drugs can be used for the treatment of influenza A infection A) Zidovudine(AZT) B) Amantadine C) Ribavirin D) Vidarabine i38.lactamase producing strain of klebsiella B) Pneumonia due to to streptococcus pneumonia C) UTI infection due to E.Which of the following drugs may cause discolouration of nail beds and mucous membranes A) Tetracycline B) Chloroquine C) Doxycycline D) Rifampicin i36.Which one of the following statements about Tetracyclines is not correct A) It is useful for treatment of resistant strains B) It is contraindicated in pregnancy .Which of the following drugs is used in the treatment of leishmaniasis A) Pyrimethamine B) Diloxamide furoate C) sodium stibogluconate D) Emetin i39. Which of the following drugs is used topically for burn patients A) Sulphacetamide B) Sulphadiazine C) Sulphasalzine D) Silver sulphadiazine i43-Which one among the following drugs is effective in the treatment if pneumonia caused by pneumocystis carinii A) Sulphacetamide B) Sulphasalzine C) Sulphisoxzole D) Co.C) It is effective infection caused by Chlamydia D) It can lead to discolouration of teeth if given to cgildren i41.In which one of the following clinical situations is the prophylactic use of antibiotics NOT warranted A) It is useful for the treatment of resistant strains B) It is contraindicated in pregnancy C) It is effective in infection caused by Chlamydia D) Patient with a heart prosthesis having a tooth removal i46.Which one of the following is both pencillinase resistant and effective by oral administration A) Pencillin V B) Methicillin C) Amoxicillin+ Clavulanic acid D) Carbimazole i42.Trimoxazole i44.Sulphonamides are useful in the treatment of which one of the following A) Influenza B) Gonorrhoea C) Urinary tract infections D) Meingococcal i45.Which of the following clinical indications will NOT require a combination of antibiotics . Oral form of gold(A) 3.Famotidine is classified as A) Anti depressant B) H1 receptor antagonist C) H2 receptor antagonist D) Beta 2 agonist i50.For each side effct(1-4).Given on an empty stomach(B) 4. list the most likely cause (A-D) .Each answer may be .May be given intra.Which of the following drug will antagonize methotrexate A) Thiamine B) Folic acid C) Biotin D) Cyanocobalamin i48.Platelet function effect© 2.All of the following aretherapeutic indications of salicylates EXCEPT A) Rhematoid arthritis B) Fever in children with varicella C) Fever in adults with influenza D) Spasmodic dysmennorhoea i49.Each answer may be used more than once A) Auranofin B) Pencillamine C)Aspirin D) Corticosteroids 1.aricularly (D) i51.Match the drug characteristics (1-4).A) Treatment of mixed infections B) Treatment of tuberculosis C) Treatment of cryptococcal meningitis D) Treatment of gonnorhoea i47. Should not be used by patients of heart failure(A) i3.F D) Belladone tincture B.P B) Aromatic ammonia spirit USP C) Acetic acid N.Which of the following is a natural emulsifuing agent A) Acacia B) Lactose C) Polysorbate 20 D) Polysorbate 80 i55.The process of rubbing or grinding a substance in a mortar is called A) Trituration B) Spactulation C) Levigation D) Coating i54.All of the following preparations contain alcohol EXCEPT A) Syrup simplex B.Can be incorporated with an antacid mixture to control diarhoea(B) i52.May cause diarrhea(D) i2.May cause dry mouth(C) i4.P .Pyridoxine requirements may increase during administration of all of the following EXCEPT A) Isoniazid B) Cycloserine C) Oral contraceptives D) Levodopa i53.used more than once A) Sodium bicarbonate B)Aluminium hydroxide C) Amitryptiline D) Magnessium hydroxide i1. inflammatory activity similar to aspirin C) Is an effective analgesic in severe renal colic D) May cause severe liver toxicity if taken in overdose i60.An inorganic molecule used in the treatment of mania is A) Aluminium hydroxide B)Cromolyn sodium C) Lithium bicarbonate D) Magnesium oxide i61.immunization in 2-3 month old infants B) Has an anti.A contraindication to the antimigraine drug sumatriptan is A)Hypotension B) Hirsuitism C) Gingival hyperplasia D) a.i56. b and c i59.Paracetamol A) Is not recommended for post.the RDA (Recommended daily allowance) of elemental iron for an adult man is A) 1-5mg B) 10-18mg C) 50-100mg D) 150-200mg i57.Which of the following is the drug of choice for an acute febrile convulsion A) Carbamazepine B) Clonazepam C) Diazepam D) Phenytion . Which of the following is chemically similar to aspirin A) Diflunisal B) Etodolac C) Sulindac D) Indomethacin i66.Which of the following components of analgesic tablets commonly causes constipation A) Aspirin B) Caffeine C) Codeine D) Paracetamol i64.Which of the following drugs has antimuscarinic activity A) Benzhexol B) Benztropine C) Procyclidine D)Al of the above i67.Which of the following chemical groups dose NOT have antidepressant activity A) Tricyclics B) Selective serotonin Reuptake Inhibitors C) Monoamine oxidase inhibitors D) Phenothiazines i65.Levodopa is A) The latin name for dopamine .Which of the following is a tricyclic anti-depressant A) Clomipramine (Anafranil)i B) Fluoxetine (Prozac)i C) Maprotilline (Ludiomil)i D) Tranylcypromine (Parnate)i i63.i62. for a 4 year old child. the maximum daily dose of paracetamol is A) 240mg B) 480 mg C)1 g D) 2 g i71.B) The amino acid precursor of dopamine C) The main m etabolite of dopamine D) The natural dopamine receptor antagonist i68.Which of the following is the amino.Which of the following agents should not be used concurrently with .Parkinson's disease is caused by a deficiency of which neurotransmitter in the substantial nigra A) Dopamine B) Noradrenaline C) Acetylcholine D) Adrenaline i69.acid precussor of dopamine A) Levodopa B) Bromocryptine C) Carbidopa D) Procyclidine i70.Which of the following is available as an injection A) Alprazolam B) Bromazepam C) Clorazepate D) Diazepam i72. Which of the folloeing CANNOT be given with a MAOI antidepressant A) Beta blocking drugs B) NSAID'S C) Benzodiazepines D) Selective Serotonin Reuptake Inhibitors i75.levodopa A) Mono Amine Oxidase Inhibitors B) Diphenhydramine C)Benztropine D) Amantadine i73.butyric-acid B) Noradrenaline .amino.Which of the following can lower the convulsion threshold (at therapeutic doses)i A) Carbamazepine (Tegretol)i B) Propanolol (Inderal)i C) Amitryptiline (Tryptizol)i D) Phenytoin (Epanutin)i i76.An example of a 5-HT3 receptor antagonist is A) Bromocryptine (Parlodel)i B) Cimetidine (Tagamet)i C) Ondanestron (Zofran)i D) Fluoxetine (Prozac)i i74.Which anticonvulsant is associated with sedation and tolerance A) Valproic acid B) Phenobarbitone C) Clonazepam D) Vigabatrin i77.Benzodiazepines mainly affect which neurotransmitter A) Gama. Select the drug of choice for preventing the DELAYED emetic symptoms of cancer chemotherapy A) 5HT 3antagonist B) Dexamethasone C) Metoclopramide D) Prochlorperazine i81.Which of the following is effective when given once daily for the prevention of epilepsy A) Carbamazepine (Tegretol) B) Sodium valproate (Epilim) C) Phenytoin (Epanutin) D) Carbamazepine (Tegretol Retard)i i82.In the elderly. an antipsychotic drug such as Haloperidol is likely to cause A) Hyperthermia B) Hypertension C) Hypotension D) Hypoprolactinaemia i80.All of the following can be used to treat pesudomembraneous colitis EXCEPT A) Vancomycin B) Metronidazole C) Cholestyramine .C) Serotonin D) Dopamine i78-Which if the following antiepileptic drugs is also used in the prophylaxis of manic depression A) Phenytoin B) Carbamazepine C) Lamotrigine D) Phenobarbitone i79. lactamase enzymes B) To make a sustained release formula C) To block the renal m etaboltsm of imipenem D) To inhibit the liver microsomal enzymes from m etabolizing imipenem i84.organisms B) It is a mono bactam C) Its usual dose is one gram every 8 hours D) It has low tendancy to causehypersensitivity in pencillin allergic patients i86-Biphosphonates are used clinically to treat A) Hypocalceamia B) Htponatreamia C) Hypercalceamia related to malignancy D) Hypokaleamia caused by diuretics i87.Which one of the followingstatements is nutrue about aztreonam A) It is active against both grampositive and gram negative micro.The following statements are true when we talk about oestrogens except A) It is responsible for female secondary sexual charscteristics B) It causes myometrial atrophy C) It can be used in post menopausal osteoporosis D) Long term treatment with oestrogen may increase the risk of endometrial cancer i89.inflammatory dose to 5mg of prednisolone A) 50mg of cortisone acetate B) 50mg of hydrocortisone C) 0.The rote of cilastatin in the combination imipenem/cilastatin is A) To inhibit beta.What is the e quivalent anti.75mg of betamethasone D) 10mg of prednisolone i88.The pharmacist's advice to a patient who is using ciprofloxacin should be that A) Do not take it directly after a meal which contains milk and dairy products B) Do not it at the same time with acids C) Separate it form calcium and iron supplements at least for2 hours D) All of the above i85.D) Clindamycin i83.Which one of the following hormones is secreted by the hypothalamus A) Gonadorelin B) Corticotropin C)Vasopressin . The most common side effect of a NSAID is A)Headache B) Naproxen C) Skin rash D) Diarrhoea i94.EXCEPT A) Ceftriaxone B) Pieracillin C) Ofloxacillin D) Imipenem i92.Which one of the following is usually given once a day A) Piroxicam B) Naproxen C) Diflunisal D) Ibuprofen i95.Which one of the nasal sprays is usually used ONCE daily A) Beclomatasone (Becotide)i .Which one of the following is the most commonly reported side effect of antipsychotics in the elderly ? A) Agranulocytosis B) Arrhythmia C) EPS D) Excessive urination i91.balance and homeostasis A) Pancreas B) Hypothalamus C) Parotid glands D) Parathyroid i93.Which one of the following can be given safely to a patient receiving an MAOI A) Cromoglicate nasal drops B) Ephedrine nasal drops C) Oxym etazoline nasal drops D) Xylom etazoline nasal drops i96.Which one of the following organs is involved in calcium.D) Genotropin i90.All the following are considered to be beta – lactam type antibiotics. Which is the most potent ear \ nose drops A) Betamethasone (Betnesol)i B) Dexamethasone (Sofradex)i C) Hydrocortisone (Otosporin)i D) Prednisolone (Predsol)i i98.Which one of the following is most closely related to aspirin A) Acetaminophhen B) Diclofenac C) Diflunisal D) Salazopyrine .Which one of the following can be used to treat acute go A) Diclofenac B) Ibuprofen C) Indomethacin D) All of the above i100.Which one of the following should be avoided during treatment with warfarin A) Amoxicillin B) Glibenclamide C) Indomethacin D) VitaminD i99.B) Dexa methasine ( Dexa rhinaspray)i C) Fluticasone (Flixonase)i D) Cromoglycate (Rynacrom)i i97. adrenergic blocking agent D) Prodrug E) Chelating agent i4.Which of the following statement are (is) true of ticlopidine HCI(Ticlid)? 1.The antiarrhythmic action of tocainide(Tono card) and mexiletine(Mexitil) most closely resembles that of A)Acebutolol B) Verapamil C) Quinidine D) Lidocaine E) Disopyramide i6.i1.Which of the following statement is (are) true of epinephrine? l.An adverse effect of commonly associated with the use of theophyllineHYH products is A) Crystaluria B) Skin Rash C) Syncope D) Ptosis E) Insomnia i2. Reduces arterial blood pressure lll. Dissolves blood clots 111. 11 and 111 i3. Inhibits platelet aggregation A) 1only B) 111 only C) 1 and 11 only D)11 and 111 only E) 1.Wghich one of the following agents may be added to local injection of Xylocaine in order to prolong its effect .11 and111 i5. Only administered parenterally 11. May be administered by inhalation ll.Dipivefrin ( proppine) can best be described as a(an)i A) Sholinesterase inhibitor B) Osmotic diuretic C) Beta. Peripheral vasodilator A) 1 only B) 111only C)1 and 11 only D) 11 and 111 only E) 1 . Colestipol HCI is most commonly employed as a (an)i A) Antidote for atropine overdosage B) Hypoglycemic agent C) Bile acid sequestrant D) Fat substi tute E) Bronchodilator i8.Which one of the following drugs dose NOT lower plasma lipoprotein Concentrations?i A) Simvastatin B) Clofibrate C) Probucol D) Cholestyramine E) Nicotinamide i9.Idoxuridine (Herplex) is an effective treatment for dentric keratitis .Isotretinoin is used therapeutically A) As a urinary analgesic B) In the treatment of cystic acne C) As an antifungal agent D) In the treatment of resistant tuberculosis E) As an osmotic diuretic .A) Succinylcholine chloride B) Sodium carbxymethylcellulose C) Polyethylene glycol D) Epinephrine i7. which is caused by A) Escherichia coli B) Pseudomonas aeruginosa C) Staphylococcus aureus D) Clostridium difficle E) Herpes simplex i11.A drug that has been shown to have a strong antagonism for both histamine and serotonin is A) Chlorpheniramine (Chlor-Tirmeton)i B) Tripolidine (Actidil)i C) Cyproheptadine (Periactin)i D) Loratidine (Claritin)i E) Promethazine (Phenergan)i i10. induced bronchospasm is A) nedocromil B) Enalapril C) Isoproterenol D) Pindolol E) Theophylline 13i. Ventolin) is a(an)i A) Alpha receptor antagonist B) Alpha receptor agonist C) Beta receptor antagonist D) Beta receptor agonist E) Alpha and Beta receptor agonist i14. pyrilamine i111.Of the following glucocorticoids.An agent that would be most likely to cause drugs.Which of the following drugs is (are) histamine antagonists?i i1. Brompheniramine 11i. which one has the greatest antiinflammatory potency when administered systemically?i A) Hydrocortisone (Cortef)i B) Dexamethasone (Decadron)i C) Triamcinolone (Aristocort)i .Albuterol(Proventil . Rantidine A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1 .i12. 11 and 111 i15. 11 and 111 i19.During ovulation .D) Prednisone (Meticorten)i E) Cortisone (Cortone)i i16. Follicle – stimulating hormone (FSH)i i111.Liotrix is a thyroid preparation that contains .Benzoyl peroxide is commonly employed in the treatment of A) Psoriasis B) Pinworms C) Acne D) Trichomonal infections E) Seborrheic dermatitis i17. peak plasma concentration(s) of Which of the following Hormone(s) will be reached?i 1i. Luteinizing hormone (LH)i A)1 only B) 111 only C)1 and 11 only D) 11 and 111 only E) 1. Progesterone i11.Which one of the following hormones is released from the posterior pituitary gland?i A) Oxytocin B) Adrenocorticotropic hormone (ACTH)i C) Thyroid – stimulating hormone (TSH)i D) Follicle – stimulating hormone(FSH)i E) Growth hormone i18. Insomnia 11.i1. Liothyronine sodium i11. Equanil) D) Chlordiazeppoxide (Librium) E) Buspirone (Buspar) i23.11 and 111 i22. Levothyroxine sodium 111i.A phenothiazine derivative commonly used for its antihistaminic effect is?i A) Promethazine B) Promazine C) Chlorpromazine D) Prochlorpromazine i21.Of the following anxiolytic agents. Desiccated thyroid A) 1 only B) 111 only C) 1 and 11 only D)11 and 111 only E) 1 . 11 and 111 20i.Carbamazepine (Tegretol) is indicated for the treatment of 1.Which of the following is (are) NOT true of theophylline? . the one that possesses the least sedating action is A) Diazepam (Valium) B) Oxazepam (Serax) C) Meprobamate (Miltown . Trigeminal neuralgia A) 1 only B) 111 only C)1 and 11 only D) 11 and 111 only E)1 . Epilepsy 111. Penicillins are believed to exert their antibacterial effect by which one of the following mechanisms? A) Detergent effect on the bacterial cell membrane B)Inhibition of protein synthesis C) Destruction of the bacterial cell nucleus D) Inhibition of bacterial cell wall synthesis E) Steric hindrance of membrane acids i25. Causes CNS depression A) 1 only B) 111 only C) 1 and 11 only D)11 and 111 only E) 1 .Chlorhexidine gluconate is most similar in action to A)Quindine gluconate B) Chlorpheniramine .Five hundred milligrams of phenoxymethyl penicillin is e quiv alent to approximately how many units of penicillin activity? A) 125. Increases the contractile force of the heart 111.000 E) 800.000 B) 200. 11 and 111 i24.000 i27. Chemically related to caffeine 11.000 C) 1600 D) 250.1.The antibacterial mechanism of the penicillins is most similar to that of A) Lincomycin (Lincocin) B) Tetracycline HCL (Achromycin) C) Ciprofloxacin (Cipro) D)Granisteron (Kytrill) E)Probenecid (Benemid) i26. y inhibiting the action of A) monoamine oxidase B) Xanthine oxidase C)Pyrimidine D) Para-aminobenzoic acid E) Uric acid i29.which one of the following tetracycline has the longest duration of action? A) Doxycline (Vibramycin) B) Tetracycline (Achromycin) C) Minocycline (Minocin) D) Oxytetracycline (Terramycin) E) Demeclocycline (Dclomycin) i31.Sulfones such as dapsone are employed commonly in the treatment of A) Urinary tract infection B) Psoriasis C) Brigh’s disease D) Hansen’s disease E) Cushing’s disease i30.C) Calcium gluconate D) Hexachlorophene E) Chloroquine phosphate i28.Sulfanomides exert a bacteriostatic effect by competitivel.Tricyclic antidepressants are believed to exert their antidepressant action by A) Potentiating GABA activity B) Increasing the effect of neurotransmitters on postsynaptic receptor sites C) Blocking alpha adrenergic receptors D) Increasing the m etabolic breakdown of biogenic amines E) Blocking beta adrenergic receptor . i32. Loperamide (Imodium) 111.As an antiarrhythmic drug . Mast cell stabilizer 11.Which of the following statements are (is) true of acetycysteine? 1. procainamide is most similar in action to which one of the following agents? A) Amiodarone B) Propranolol C) Digoxin D) Verapamil E) Quinidine i35.Which of the following agents has (have) been found useful in the treatment of rheumatoid arthritis? 1.Methylxanthines such as caffeine and theophylline exert all of the following Pharmacologic effects EXCEPT A) Cardiac stimulation B) Peripheral vasoconstriction C) Relaxation of smooth muscle D) Diuresis E) CNS stimulation i33. Auronafin (Ridaura) A) 1only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1 . 11 and 111 i34. Acetaminophen antidote 111. Ergotamine tartrate (Ergostat) 11. Mucolytic A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only . Mafenide A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1 . Selegiline (Eldepryl) A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1 . 11 and 111 i39. HMG-CoA reductase inhibitor A) 1 only B)111 only C)1 and 11 only D)11 and 111 only E)1 . Pergolide(Permax) 111. 11 and 111 i38. Antihypertensive agent 11.11 and 111 i37. Pregnancy category X 111.E) 1 .Which of the following is (are) employed as antifungal agents? 1. Natamycin 11.Which of the following is (are) true of pravastatin? 1.Agents that are employed as gastric stimulants include . Clorimazole 111.11 and 111 i36. Bromocriptine (Parlodel) 11.Which of the following is (are) dopaminergic antipkinson agents? 1. Polymyxin B is pharmacologically and microbilogically similar to A) Ampicillin (Polycillin) B)Colistin ( Coly.1.11 and111 i40. Cysteinuria A) 1 only B) 111 only C)1 and 11 only D)11 and 111 only E) 1.Methimazole (tapozle) is used for the same therapeutic indication as A) Methaxsalen B)Danazole C) Propylthiouracil D) omeprazole E) Azathioprine i41. Cisapride 111.Pencillamine is a drug used therapeuptically for the treatment 0f 1. Rheumatoid arthritis 111. 11 and 111 i42. Wilson's disease 11. Omeprazole 11.Mycin S) C) Gentamicin (Garamycin) D) Penicillin G . Metoclopramide A) 1 only B) 111 0nly C)1 and 11 only D)11 and 111 only E)1 . Phytonadione A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1 . Fluoxetine (Prozac) 111.E) Tetracycline (Achromycin) i43. 11 and 111 i45.Agents indicated for the treatment of depression include (is) 1. Ticlopidine 111.Carbidopa can best be classified as a drug that A) Reverses aymptoms of Parkinson's disease .Potentially fatal aplastic anemia is toxic effect associated with A) Ciprofloxacin (cipro) B) Cefadroxil (Duracef) C) Disopyramide (Norpace) D) Clindamycin (Cleocin) E) Chloramphenicol (Chloromycetin) i44. Phenelzine (Nardil) A) 1 only B) 111 only C)1 and 11 only D)11 and 111 only E)1 . Bupropion (Wellbutrin) 11. 11 and 111 i46.Enhanced clotting ability of the blood is associated with the administration of 1. Tocopherol 11. B) Exerts an anticholinergic action C) Is adopa – decarboxylase inhibitor D) Is a neuromuscular blocking agent E) Is a skeletal muscle relaxant i47- Isotretinoin (Accutane) is a drug employed in the treatment of severe recalcitrant cystic acne. Which one of the following is NOT an adverse effect associated with its use? A) Hyperglycemia B) Hypertriglyceridemia C) Pseudotumor cerebri D) Conjuctivitis E) Fatal abnormalities i48- Which of the following is true of isotretinoin (Accutane) A) Commonly causes cheilitis B) A derivative of vitamin D C) Is applied topically to severe acne lesions D) Contraindicated in patients with diabetes E) May be used safely in pregnant patients after the first trimester i49- Endorphins are A) Endogenous opioid peptides B) A new class of topical anti- inflammatory agents C) Neuromuscular blocking agents D) Biogenic amines believed to cause schizophrenia E) Endogenous chelating agents i50- Lovastatin (Mevacor) is contraindicated for use in patients who are A) Hypersensitive to aspirin B) Pregnant C) Chronic asthmatics D) More than 25 % over ideal body weight E) Diabetics i51- Which of the following drugs is a available in a transdermal dosage form for use in the prevention of nausea and vomiting associated with motion sickness in adults A) Metoclopramide B) Ondansetron C) Scopolamine D) Clonidine E) Granisetron i52- Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis? A) Ritodine (Yutopar) B) Amoxapine (Asendin) C)Metolazone (Zaroxolyn) D) Desmopressin acetate (DDAVP) E) Methenamine hippurate (Urex) i53- An example of a benzodiazepine that is not m etabolized to active m etabolites in the body is A) Triazolam B) Chlordiazepoxide C) zolpidem D) Diazapam E) Halazepam i54- Which of the following , antimicrobial agens would be MOST useful in the treatment of an infection caused by nbeta lectamase- producing staphylococci? A) Amoxicillin B) Cephapirin C) Cephalexin D) Dicloxacillin E) Bacampicillin i55- Gastric intrinsic factor is a glycoprotein that is required for the Gastrointestinal absorption of A) Medium chain triglycerides B) Folic acid C) Iron D) Tocopherols E) Cyanocobalamin i56- Gingival hyperplasia, hirsutiam, and ataxia are adverse effects associated with the use of A) Minoxidil B) Chlorpromazine C)Ginseng root D) Phenytoin (Dilantin) E) Ciprofloxacin (Cipro) i57- Levobunolol (Betagan) is a drug used in the treatment of glaucoma. Which one of the following best describes the action it exerts on the eye? A) Miotic B) Decreases the production of aqueous humor C) Interferes with the enzyme carbonic anhydrase D) Acts as an osmotic diuretic E) Mydriatic i58- Cardioselectivity is a property of which of the following beta adrenergic blocking agents? 1.Carteolol (ocupress) 11. Metipranolol HCI (Optipranolol) 111. Betaxolol(Betoptic) A) 1only B)111 only C)1 and 11 only D) 11 and 111 only E) 1, 11 and 111 i59- Which of the following is (are) a property or an action of pilocarpine? 1. Direct acting miotic 11. Ingredient in Ocusert ocular therapeutic system 111. Similar pharmacologic action to dorozolamide(Trusopt) A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1,11 and111 i60- Which one of the following is NOT an effect of atropine on the human body?\ A) Cardiac stimulation B) Diminished sweating C) Mydriasis D) Reduction of gastrointestinal tone E) Stimulation of gastric secretion i61- Which one of the following statement best describes the mechanism of action of antihistaminic drugs? A) They interfere with the synthesis of histamine in the body B) They form inactive complexes with histamine C) They stimulate the m etabolism of endogenous histamine D) They blok the receptor sites on which histamine acts E) They are alpha- adrenergic blockers i62- Haloperidol (Halol) differs from chlorpromazine (Thorazine) in that haloperidol A) Is not an antipsychotic agent B) Dose not produce extrapyramidal effects C) Is not a phenothiazine D) Dose not cause sedation E) Cannot be administered parenterally i63- Tomoxifen(Nolvadex) is an agent that can best be described as a (an) A) Gonadotropin- releasing hormone analog B) Antiestrogen C) Enstrogen D) Progestin E) Androgen i64- Which of the following ia (are) true of auranofin (Ridaura)? 1. May cause thrombocytopenia 11. Orally administered form of gold therapy 111. Its use may result in renal impairment A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1 , 11 and 111 i65- Advantages of acetaminophen over aspirin include all of the following EXCEPT? A) No alteration of bleeding time B) Less gastric irritation C) No occultblood loss D) No appreciable effect on uric acid excretion E) Greater anti- inflammatory action i66-The use of clozapine (Clozaril) has been associated with the development of A) Thrombocytopenia B) Hypercalcemia C) Aranulocytosis D) Meningitis E) Hyperuricemia i67-Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an) A) Immunosuppresant effect B) Antiviral effect C) Ability to "sterilize" blood D) Anabolic effect E) Cytotoxic effect i68- The anti-inflammatory effect of aspirin is due to 1. Resetting of the hypothalamic "setpoint" 11. Adrenal stimulation 111. Inhibition of prostaglandin synthesis A) 1 only B) 111 only C)1 and 11 only D) 11 and 111 only E) 1, 11 and 111 i69- The first dose effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of. 1. Bepridil (Vascor) 11. Terazosin (Hytrin) 111. Prazosin (Minipress) A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1, 11 and 111 i70- Carbon monoxide exerts its toxic primarily by A) Reacting with blood enzymes to produce acidic substances B)Decreasing the oxygen- carrying capacity of the blood C) Reacting with amino acids in the body to form ammonia D) Inhibiting the gag reflex E) Paralyzing the muscles of the diaphragm i71- The most serious potential consequence of indestion of a liquid hydrocarbon such as kerosene or gasoline is A) The aspiration of the position into respiratory tract B) The corrosive action of the position on the stomach lining C) The paralysis of peristaltic motion of the GI tract D) Dissolution of the mucoid coat of the esophagus E) The destruction of body enzymes by the poison i72- Deferoxamine mesylate is considered to be a specific antidote for the treatment of poisoning caused by A) Anticholinergic agents B) Opiate narcotics C) Benzodiazepines D) Loop diuretics E) Iron containing products i73- Which one of the following agents is classified pharmacologically as a carbonic anhydrase inhibitor A) Indapamide (Lozol) B) Acetazolamide (iamox) C) Chlorthalidone (Hygroton) D) Torsemide (Demadex) E) Amiloride (Midamor) i74- The thiazide diuretics decease the excretion of A) Uric acid B) Urea C)Sodium D) Bicarbonate E) Creatinine i75- The renal excretion of amphetamines can be diminished by alkalinization of the urine. Which of the following would tend to diminish the excretion rate of amphetamine sulfate? 1. methenamine mandelate 11. Sodium bicarbonate 111. Acetazolamide A) 1 only B) 111 only C) 1 and 11 only D)2 only E) 11 and 111 only i76- An agent emplyed in relieving signs and symptoms of spasticity resulting from multiple sclerosis is A) Buspirone (Buspar) B) Dantrolene (Dantrium) C) Ursodiol (Actigall) D) Mexiletine (Mexitil) E) Amiodarone (Cordarone) i77- Which of the following is (are) MAO inhibitors? 1. Pargyline (Eutonyl) 11. Tranylcypromine(parnate) 111. Cyclobenzaprine (Flexeril) A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1, 11 and 111 i78- Arug that is indicated for the treatment of both diarrhea and constipation is A) Bisacodyl (Dulcolax) B) Lactulose (Cephylac) C) Magnesium sulfate D) Senna (Senokot) E) Polycarbophil (Mitrolan) i79- Which one of the following is microsomal enzyme inducer? A) Indomethacin B) Rifampin C) Tolbutamide D) Tobramycin E) Ibyprofen i80- The thiazide derivative diazoxide (Hyperstat) A) Is a stronger diuretic than hydrochlorothiazide B) Is not a diuretic C) Produces about the same diuretic response as an equal dose of hydrochlorothiazide D) Produces diuretics in normotensive subjects only E) Is a pressor agent i81- Which of the following is (are) broad- spectrum antifungal agents? 1. Griseofulvin 11. Ketaokonazole 111. Miconazole A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1, 11 and 111 i82- Which of the following barbiturates is used as an intravenous anesthetic? A) Mephobarbital B)Amobarbital C) Methohexital sodium D) Pentobarbital sodium E) Secobarbital sodium i83- The most useful drug the treatment of diabetes insipidus is A) Chlorpropamide (Diabinese) B) Glucagen C) Insulin D) Glyburide (Micronase) E) Lypressin (Diapid) i84- A pharmacist receives a pres criription order for indimethacin (Indocin) capsules. He/she should consult with physician if the mediation record indicates that the patient A) Has gout B) Has arthritis C) Has a peptic ulcer D) Has insomnia E)Is hypertensive i85- The sulfonylyreas (eg. Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by A) Decreasing the desire for sugar consumption B) Inhibiting breakdown of endogenous insulin C) Enhancing the effectiveness of the small amounts of insulin that the diabetic can produce D) Increasing the peripheral utilization of glucose E) Stimulating the release of insulin from the pancreas i86- Which of the following hypoglycemic drugs has longest serum half life? A) Acetohexamide (Dymelor) B) Tolbutamide (Orinase) C) Glyburide (Diabinese, Micronase) D) Chlorpropamide (Diabinese) E) All of the above about the same serum half life i87- Vidarabine(Vira- A) is an antiviral agent indicated for the treatment of A) Rubella B) Smallpox C) Influenza D) Pneumocystis carini pneumonia (PCP) E) Herpes simplex encephalitis i88- Zidovudine (Retrovir) is indicated for the treatment of patients with 1. Influenza A virus infection 11. Herpes simplex infection 111. human immunodefiency virus (HIV) infection A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E) 1, 11 and 111 i89- Which one the following statement is true of alteplase (Activase)? A) It is derived from bovine tissue Calan) A) 1 only B) 111 only C) 1and 11 only D) 11 and 111 only E) 1. V erapamil (Isoptin.adrenergic blocking agents has intrinsic sympathomimetic activity (ISA)? . Amlodipine (Norvasc) 11.Cromylin sodium (Intal.Which one of the following is NOT a progestin? A) Norethynodrel B) Norethindrone C) Ethynodiol diacetate D) Levenorgestrel E) Mestranol i93. 11 and 111 i92. Nasalcrom. Opticrom) is a drug that is A) Effective in acute asthmatic attacks B) A synthetic corticosteroid C) A histamine antagonist D) A theophylline derivative E) A mast cell stabilizer i91. Isradipine (DynaCirc) 111.Which one of the following beta.Which one of the following calcium channel blockers may be employed parentera 1.B) It is thrombolytic agent C) It is derived from porcine tissue D) It is an anticoagulant E) It is administered intramuscularly Ans B i90. A drug that is effective in the treatment of alcohol withdrawal syndromes and in the prevention of delirium tremens is A) Disulfiram (Antabuse) B) Methadone (Dolophine) C) Phenytion (Dilantin) D) Chlordiazepoxide (Librium) E) Haloperidol (Haldol) .Potassium supplementation is LEAST likely to be required in a patient using A) Ethacrynic acid (Edecrin) B) Chlorthalidone (Hygroton) C) Furosemide (Lasix) D) Acetazolamide (Diamox) E) Triamterene (Dyrenium) i96.Torsemide (Demadex) is most similar in action to A) Spironolactone (Aldactone) B) Risperidone (Risperdal) C) Bum etanide (bumex) D)Chlorthalidone (Hygroton) E) Acetazolamide (Diamox) i95.A) Esmolol(Brevibloc) B) Atenolo (Tenormin) C) Pindolol(Visken) D) Metoprolol (Lopressor) E) Propranolol HCL (Inderal) i94.Acyclovir (Zovirax) is indicated for the treatment of A) Shingles B) Pseudomembranous enterocolitis C) HIV infection D) Measles E) Influenza caused by influenza A virus strains i97. Nephrotoxicity limits its parenteral use A) 1 only B) 111 only C) 1 and 11 only D) 11 and 111 only E)1 .i98.Olzalazine sodium (Dipentum) is employed in the treatment of A) Diabetes mellitus B) Duodenal ulcers C) Ulcerative colitis D) Urinary tract infections E) Diabetes insipidus i100.Which one of the following statement is TRUE of bacitracin? 1. It is effective intreating Pseudomonas infection 11.Beta carotene is considered to be a precursor for A) Betaseron B)Beta interferon C) Vitamin D D) Vitamin A E) Carteolol . 11 and 111 i99. It is an aminoglycoside antimicrobial agent 111. Which of the following drugs inhibits the formation of uric acid A) Aspirin B) Colchicine C) Allopurinol D) Sodium salicylate i2.i1.The possible interaction between Cisapride (Prepulsid) and Hyoscine butyl A) Cisapride will increase the antimuscarinic side effect of Buscopan B) They counteract the effect of each other C) Buscopan will increase the adverse effects of cisapride D) Cisapride will displace Buscopan from the plasma protein binding sites .Which of the following is not true about Simvastatin A) It is a HMG CoA reductase inhibitor B) Its main adverse effect is Gl disturbances C) Concomittant administration of Simvastatin with cyclosporine is associated with increased risk of myopathy D) The dose should be adjusted in renal failure patients i7.In interaction of Amiloride with Caotopril there is a possibility of A) Hypokaleamia B) Hyperkaleamia C) Hypocalcamia D)Hypophosphateamia i6.The antihypertensive effect of Guanethidine is inhibited by which of the following A) Diazepam B) Amitryptilline C) Hydrochlorthiazide D) Nitrofurantoin i5.Which of the following is NOT an indication if digoxin A) Congestive heart failure B) Atrial fibrillation or atrial flutter C) Ventricular tachycardia D) Sinus tachycardia caused by congestive heart failure i3.The therapeutic effect of warfarin is achieved by A) Dissolving existing thrombi B) Preventing the thrombus formation when blood stasis occurs C) Preventing the renal synthesis of Vitamin K D) Preventing the thrombus formation n vitro i4. Which of the following ACE inhibitors has the shortest duration of action A) Enalapril B) Captopril C) Lisinopril D) Perindopril i14.Vomitting B) Constipation C) Diarrhoea D) Gl bleeding i10.i8.A disadvantage in the use of cimetidine. is its ability cause A) Hair growth B) Decreased prolactin secretion C) Inhibition of hepatic microsomal enzymes D) Oesophageal reflux i11.Which of the following dose not lower plasma lipoprotein concentrations A) Nicotinamide B) Simvastatin C) Cholestyramine D) Gemfibrozil i9.The most common side effect related to the use of Aluminium containing antacids is A) Nausea.Regular use of sublingual doses of Glyceryl trinitrate is likely to result in the development of A) Hepatotoxicity B) Nephrotoxicity C) Tolerance D) Respiratory impairment i12.Gastric intrinsic factor is a glycoprotein that is required for Gl absorption A) Vitamine B12 B)Folic acid C) Iron D) Calcium i13.Which of the following antacids is most likely to induce rebound acidity A) Aluminium hydroxide B)Magnesium hydroxide . arrythmais and convulsions A) Aminophylline B) Prednisolone C) Adrenaline D) Beclomethasone i20.Which of the following drugs is suitable to treat a hypertensive patient who also has Asthma and Hyperuriceamia A) Amlodipine B) Hydrochlorthiazide C) Moduretic D) Propanolol i18.Which of the following is most likely to have long term side effects when used to treat asthma in a 10 yr old child A) Daily administration of salbutamol by inhaler B) Daily administration of prednisolone by mouth C) Daily administration of beclomethasone by inhaler D) Daily administration of cromolyn by inhaler .Sucralfate is best described as a \an A) Artificial sweetner B) Denaturing agent for alcohol C) Ulcer protectant D) Oral hypoglyceamic i17.C) Simethicone D) Calcium carbonate i15.Cromolyn is used in the following EXCEPT A) In preventing food allergy B) For local application to the eye C) For local application to the nose D) For local application to the skin i19.Apatient who has excessive levels of amylase indicate a disease of the A) Liver B) Heart C) Pancreas D) Kidney i16.Anoverdose of which drug can cause insomnia. cell.i21.stabilizer D) Glucocorticoid i25.Which of the following statements is NOT TRUE about clindamycin A) It is effective against staphylococcus aureus B) It is effective against anaerobic organisms C) The major side effect is Pseudomembraneous colitis D) It is indicated for serious bone infections i24.Chloramphenicol is the drug of choice in A) Symptomatic salmonella infections B) Tuberculosis C) Cholera D) Streptococcal pharyngitis i23.Nedocromil is classified as A) A beta.Which of the following drugs DOES NOT cause insomnia A) MAO'S B) Caffeine C) Beta blockers D) Barbiturates .stabilizer D) Muscarinic antagonist i26.Which of the following statements is NOT TRUE about Diphenhydramine A) It has an expectorant effect B) It has an antihistaminic effect C) It has an atropine like effect D) It is contraindicated in patients with prostate hypertrophy i27.agonist B) Methylxanthine C) Mast.Salmeterol is a A) A beta-agonist B) Methylxanthine C) Mast-cell.Which of the following antibiotics is ONLY used topically A) Polymixin B B) Pencillin G C) Carbenicillin D) Clindamycin i22. Which of the following can reduce the effectiveness of sulphonamides antibiotics A) Folic acid B) Pantothenic acid C) Vitamin B12 D) Methotrexate i29.microsomal enzymes D) Inhibition of microsomal enzymes i34.Which of the following is the most effective drug for the treatment of motion sickness A) metoclopramide B) ondanestron C) Prochlorperazine D) cinnarizine i30.i28.Phenobarbital will interact with warfarin through which mechanism A) Induction of microsomal enzymes B) Induction of non.If a CNS drug is extensively ionized at the PH of blood. it will A) Penetrate the Blood brain Barrier slowly B) Penetrate the Blood brain Barrier rapidly C) Be eliminated slowly D) Not be distributed to any tissue sites i32.g.Which one of the following is a benzodiazepine anxiolytic drug A) Buspirone B) Lorazepam C) Haloperidol D) Pimozide i31. Glibenclamide (Daonil)act by A) I ncreasing the secretion of insulin from beta cells B) Increasing the uptake of glucose by muscle C) Reducing the hepatic synthesis of glucose D) All of the above i35.Which of the following is NOT an indication of Tranexamic acid A) Treatment of haemorrhage associated with excessive fibrinolysis B) An antidote for streptokinase overdose C) Prophylaxis of hereditary angioedema D) Prevent haemorrhage due to heparin overdose i33.microsomal enzymes C) Inhibition of non.Which of the following is NOT a third generation cephalosporin A) Cefuroxime B) Cefriaxone C) Ceftazidime .Sulphonyureas e. Which of the following drugs has alow therapeutic index A) Dioxin (Lanoxin) B) Dilitiazem( Dilzem) C) Theophylline (Theodur) D) a and c above i37.Which of the following salts commonly cause diarrhea A) Aluminum hydroxide B) Ferrous sulphate C) Magnesium hydroxide D) All of the above i38.Which of the following is a gram positive bacteria A) Streptococcus faecalis B) Salmonells typhi C) Haemophilus influenza D) E.cholesterol A)Cholestyramine (Questran) B) Fluvastatin (Lescol) C) Gemfibrosil (Lopid) D) Simvastatin (Zocor) i43.Whichof the following insulins has the longest duration of action A) Actrapid B) Insultard C) Monotard D) Ultralente i42.Which of the following drugs is SAFE in G6PD deficiency A) Cephalexin .D) Cefotaxime i36.Tamoxifen (Nolvadex) is A) Progesterone receptor antagonist B) Progesterone receptor agonist C) Oestrogen receptor agonist D) Oestrogen receptor antagonist i41.Which of the following can be used safely to treat diabetes in pregnancy A) Metformin (Glucophage) B) Glibenclamide (Daonil) C) Insulin D) None of the above i40. Coli i39.Which of the following can increase the level of HDL. Cromolyn sodium(Intal) acts via A)Antagonism of H-1 receptors B) Relaxation of bronchial smooth muscle .Which of the following is a natural emulsifying agent A) Acacia B) Lactose C) Polysorbate 20 D)Sorbittan monopalmitate i46.Which of the following is a prostaglandin analogue A) Cimetidine B) Misoprostol C) Omeprazole D) Sucralfate i45.The specific antagonist for benzodiazepine overdose is A) Flucytosine B) Flumazenil C) Flunarizine D) Flurazepam i50.B) Dapsone C) Primaquin D) Sulphamethoxazole i44.Inhibitors A) Alopecia B) Cough C) Hypokaleamia D) All of the above i48.Cocoa butter (Theobroma oil) exhibits all of the following properties except that A) It meits between 33 and 35 degrees centigrade B) It is a mixture of glycerides C) It is useful in formulating suppositories D) It is soluble in water i47.Which of the following is an occasional side effect of the ACE.Ibuprofen is a A) Fenamate derivative B) Propionic acid derivative C)Pyrazolline derivative D) None of the above i49.In asthma. According to recent evidence.inflammatory A) 500 to 1g B) 1g to 2g C) more than 3g D) 75 mg daily i55.Which of the following can be used safely in a patient who is allergic to aspirin A)Diclofenac B) Ibuprofen C) Meloxicam D) None of the above i53. which of the following is associated with the lowest risk of gastro.C) Stabilization of epithelial mast cells D) None of the above i51.intestinal side –effect A) Diclofenac B) Ibuprofen C) Naproxen D) Piroxicam i52.What daily dose of aspirin is considered to be anti.Which one of the following blocks the neuromuscular junction A) Baclofen B) Chlordiazepoxide C) Diazepam D) Vecuronium .Which one of the following must be avoided during treatment with methotrexate A) Aspirin B) Cimetidine C) Folic acid D) Metoclopramide i54. i56- The expiry date of a drug is usually the time when potency falls below A) 90% B) 85 % C)80% D) 75 % i57- The term "store in a cool place "means that the temperature must not exceed A) 4 centigrade B) 10 centigrade C) 15 centigrade D) 30 centigrade i58- Which of the following is the drug of choice for an acute febrile convulsion A) Carbamazepine B) Clonazepam C) Diazepam D) Phenytoin i59- Peripheral neuritis due to isoniazid can be avoided by giving which vitamin A) Ascorbic acid B) Pyridoxine C) Riboflavine D) Thiamine i60- Tuberculosis is treated with a combination of drugs because A) This prevents the emergence of resistant organisms B) Itimproves drug penetration in to the mycobacterium C) It minimizes the rifampicin toxicity D) Itminimizes the isoniazid toxicity i61- According to USP,if a medicine expires "January 2001" it must not be used after A) January 01,2001 B) January15,2001 C) January 31,2001 D) December 31,2001 i62- The antibacterial mechanism of penicillin is most similar to A) Clindamycin ( Dalacin B) Tetracycline (Achromycin) C) Ciprofloxacin (Ciprobay) D) Cefachlor (Ceclor i63- Which of the following statements about Doxycycline is NOT true A) It is mainly excreted in the faeces B) It commonly causes gastrointestinal distress C) Its absorption is inhibited bt antacids and milk D) It may produce phototoxic reaction on exposure to sunlight i64- Which of the following antibioitics should be administered to a patient whose renal function is severly compromised A) Erythromycin B) Tobramycin C) Norfloxacillin D) Piperacillin i65- All of the following agents cause their toxic effects by interferences in DNA trans cription A) Cisplatin B) Tamoxifen C) Doxorubicin D) Cyclophosphamide i66- Hyperkaleamia is a contraindication to the use of A) Chlorthalidone B) Acetazolamide C) Spironolactone D) Chlorthalidone i67- Which of the following is not a beta-lactam abntibiotic A) Aztreonam B) Imipenem C) Streptomycin D) Ampicillin i68- Which of the following is not recommended for the amanagement of allergic rhinitis A) Systemic nasal decongestants B) Corticosteroids C) Cromoglycate D) Nedocromil i69- Which of the following is a risk factor for heart disease A) Low HDL cholesterol B) Low LDL cholesterol C) Low triglycerides D) Low VLDL cholesterol i70- Which of the following is TRUE A) Procainamide is m etabolized more slowly than procaine B) Sulphonyureas are oral anticoagulant C) An immediate IV injection salbutamol is used to treat acute systemic anaphylaxis D) Ketamine is used in the treatment of migraine i71- Which of the following can be used in the treatment of diabetes insipidus A) Metformin B) Glucagon C) Vasopressin D) Insulin i72- Mannitol may be useful in all the following treatments EXCEPT A) Treatment of pulmonary oedema with congestive heart failure B) Diagnostic evaluation of acute oligourea C) Treatment of elevated intraoccula pressure D) Prophylaxis of acute renal failure i73- Omeprazole should only be used on pres cription because A) It is expensive B) It has many drug interactions C) It can mask the symptoms of gastric cancer D) It can cause hepatitis i74- Histamine induced broncho-constriction is due to the activation of A) H1 receptors B) H2 receptors C) H3 receptors D) Allof the above i75- Which of the following medicine is available as an OTC medicine in the treatment of nausea and vomiting A) Dimenhydrinate B) Prochlorperazine C) Meclozine D) Chlorpromazine i76- In Addison's disease the proper replacement therapy should be A) Glucocorticoid plus mineralocorticoid B) Mineralocorticoid therapy alone C) Glucocorticoid therapy alone D) Tetracosactrin ( analogue of ACTH) i77- Streptomycini is an antibiotic indicated for the treatment of A) Gram-negative bacterial septiceamia B) Tuberculosis C) Pencillin-resistant gonococcal infection D) Syphillis i78- In the treatment of chronic obstructive pulmonary disease (COPD), inhaled corticosteroids A) Are more effective in the treatment of asthma B) Are more beneficial when used alone C) Produce more side effects than when used in the oral form D) Should be used for at least 2 weeks before efficacy is assessed i79- The primary goals of asthma therapy include all the following EXCEPT A) Treatment of secondary complications B) Management of acute attacks C) Chronic symptom management D) Prevention of lung tissue destruction i80- In the emergency room,the preferred first line therapy for asthma is A) Theophyline B) Beta- agonists C) Corticosteroid i81- Ceftriaxone can be used in A) Gonorrhoea B) Typhoid fever C) Meningococcal meningitis D) All of the above i82- Which statement would most accurately describe the antibacterial of tetracycline antibiotics A) They are bacteriostatic B) They inhibit protein synthesis by binding to the 30s ribosomal unit C) They inhibit bacterial cell wall synthesis D) All of the above i83) Which of the following corticosteroids has the highest mineralocorticoid activity A) Cortisone acetate B) Hydrocortisone C) Fludrocortisone D) Betamethasone i84- The recommended maintenance dose of Ranitidine for peptic ulcer is A) 150 mg at night B) 300 mg at night C) 150 mg twice daily D) 300 mg twice daily i85- Which of the following is NOT an indication for desmopressin A) Diabetees insipidus B) Primary nocturnal eneuresis C) Renal function testing D) Prostate atrophy i86- A hypertensive patient should be encouraged to A) Reduce the amount of salt in their diet B) Increase the amount of salt in their diet C) Drink more water if they eat a salty meal D) Reduce their fluid intake i87- Which of the following is NOT true of methadone A) Can be given orally or parenterally B) It is a narcotic antagonist C) It is an addictive drug D) It has significant analgesic activity i88- Select the drug of choice foe the treatment of an otitis externa caused by staphylococcus A) Aluminium acetate B) Neomycin C) Chloramphenicol D) Flucloxacillin i89- Caffeine toxicity may include all of the following symptoms EXCEPT A) Cough B) Anxiety C) Reslessness D) Muscle twitching i90- A bacteriostatic agent has which of the following effects on bacteria A) It kills bacteria on contact B) It dehydrates bacteria C) It inhibits multiplication of bacteria D) All of the above i91- A patient in diabetic coma A) May have the adour of acetone on their breath B) Usually recovers without treatment C) May tremor excessively D) None of the above i92- All of the following drugs may be used for the therapy of hypertensive emergency crisis EXCEPT A) Furosemide B) Diazoxide C) Nifedipine D) propanolol i93- ACE inhibitors are associated with a high incidence of which of the following adverse reactions A) Hepatitis B) Hypokaleamia C) Agranulocytosis D) Cough i94- Barbiturates containing a sulphur atom are usually A) Short acting B) Ultrashort acting C) Iong acting D) Medium acting i95-Adecrease in HDL/LDL ratio indicates A) Increased triacyl glycerol B) Increased mobilization of fat C) Low risk for artherosclerosis D) Increased esterification of cholesterol i95- Diverticulosis is associated with A) Stomach B) Small intestine C) liver D) Colon i96- Dyspnoea means A) Painful muscle spasm B) Pain in the heart C) difficulty in breathing D) none of the above i97- Esters are formed by the reaction between A) Acids and bases B) Acids and alcohols C) Acids and aldehydes D) Acids and ketones i98- For how long should the patient wait after stopping MAO inhibitor's before he starts on Tricyclic antidepressants A) 1 months B) 2 months C) 2 weeks D) 3 days i99- Glipizide is used to true A) Peptic ulcer B) Diabetes C) Colitis D) Infections i100- In running person Which of the following occurs A) Hyperventilation B) Tachycardia C) Increased BP D) Increased stroke volume E) All of the above i1- Drugs given systemically may cause all the following EXCEPT A) Hair loss B) Chronic urticaria C) Erythema multiform D)Fungal infections of the skin i 2- Grape fruit juice should be avoided with many drugs because A) It spoils the taste B) It increases the drug metabolism C) It decreases the drug metabolism D) It delays gastric emptying i 3- Grave's disease may be characterized by A) Hypothyroidism B) Hepatic cirrhosis C) Cortisol insufficiency D) Hyperthyroidism i 4- Hypercalceamia dose not occur in normal individuals because A) Calcium is rapidly excreted B) Calcium is rapidly biotransformed C) Calcium is insoluble D) Exccess calcium is most absorbed i 5- Hyper- responsiveness of the trachea and bronchi to stimuli with bronchi to stimuli with bronchiolar constriction and symptoms of wheezing and dyspnoea describes A) Chronic obstruction B) Asthma C) Pneumonia D) Chrocic obstructive pulmonary disease i 6- If a CNS drug is extensively ionized at the PH of blood ,it will A) Penetrate the Blood Brain Barrier slowly B) Penetrate the Blood Brain Barrier rapidly C) Be eliminated slowly D) Not be distributed to any tissue sties i 7- In a hypertensive patient taking insulin which of the following drugs to be used with extra caution and advice to the patient A) Hydralazine B) Prazosin C) Propanolol D) Methyldopa i 8- In migraine management, which one of the following is contraindicated in ischeamic heart disease A) Pizotifen B) Sumatriptan C) Propanolol D) Flunarizine i 9- Iron is required by the body to maintain normal A) Digestion B) Bone growth C) Vitamin absorption D) Oxygen transport i 10- Levocabastine nasal drops are classified as A) Corticosteroid B) Sympathomimetic C) Antihistamine D) Astringent i11- Lidocaine HCL is not usually administered orally because it is A) Has no systemic activity B) Too acidic C) Too basic D) a cause of arrhythmia i 12- Megaloblastic aneamia may be responsive to administration of all of the following EXCEPT A) Cyanocobalamin B) Intrinsic factor concentrate C) Ferrous sulphate D) Folic acid i 13- Nasal carriage of Methicillin Resistant Staphylococcus Aureus (MRSA) can be treated with ointment that contains A) Mupirocin B) Gentamycin C) Nystatin D) Chloramphenicol i 14- Oestrogens tend to increase the risk of A) Endometrial carcinoma B) Hirsuitism The normal range of FASTING blood glucose is A) 3.The anti diuretic hormone is secreted from A) The renal cortex B) The renal medulla C) The adrenal cortex D) the posterior pituitary i21.0mmol/L (55-75mg/dL) B) 4.The approximate Equivalent dose of Lorazepam to 5mg of Diazepam is A) 0.0mmol/L (75-150mg/dL) C) 8.5mg B) 4mg .0-8.0-4.0-10.0mmol/L (150-180mg/dL) D) 5.Radioactive isotopes of which substance are used widely in diagnosis andtherapy A) Carbon B) Iodine C) Radium D) None of the above i 18.Pencillamime is the antidote for A) Copper and lead B) Iron C) Cobalt D) None of the above i 16-Prostaglandins are chemically similar to A) Proteins B) Carbohydrates C) Lipids D) Enzymes i 17.C) Hearing loss D) Visual problems i 15.0mmol/L (90-110mg/dL) i 20.0-6.The anti obesity drug Orlistat acts mainly by A) Inhibition of glucose absorption from GIT B) Inhibition of fat digestion by inhibiting pancreatic lipase C) Inhibition of bile salt secretion D) Chelate with amino acids and prevent their uptake through the GIT wall i22.Sertraline is classified as A) Selective Mono amine oxidase inhibitor B) Selective serotonin reuptake inhibitor C) Tricyclic antidepressant D) Dopamine receptor blocker i 19. The dose of a drug is 0.003g B) 0.2.010g C) 0.C) 5mg D) 0.05g i25.The main function of the gall bladder is to A) Concentrate bile B) Secrete bile .The drug of choice for treating an acute attack of re-entrant supraventricular tachycardia A) Verapamil B) Digitalis C) Propanolol D) Phenylepherine i26.5 mg/kg What dose should be given to a 6 yr.033g D) 0. old child who weighs 44 lbs.1mg i23.The breakdown of glycogen is initiated by A) Trypsin B) glucagons C) Pepsin D) Renin i24.The least stable of water soluble vitamins is A) Ascorbic acid B) Thiamine C) Niacin D) Folic acid i28.2 lbs =1kg approximately A) 0.The enzymes involved in ethanol metabolism are peimarily A) Lipases B) Ketases C) Dehydrogenases D) None of the above i27. The most prevalent type of white blood cells are the A) Monocytes B) Lymphocytes C) Neutrophils D) Basophils 32.Tocopherols are a form of A) Vitamin A B) Vitamin E .The major mechanism f degradation of drugs in the Gl tract is A) Oxidation B) Hydrolysis C) Reduction D) Conjugation i30.C) Eliminate bile D) None of the above i29.The manifestations of Myasthenia Gravis are due to A) hypertonicity of smooth muscles B) Hypertonicity of striated muscles C) Weakness of striated muscles D) Sclerosis os striated muscl i31.The sympathetic ganglia are located A)Near the heart B) Near the spinal cord C) Near the adrenal glands D) Near the tissues they innervate 35.The parathyroid gland is responsible for A) Pulmonary function B) Maintaining the parasympathetic nervous system C) Cardiac output D) Calcium metabolism 33.The primary function of gastrointestinal villi is A) Facilitating the passage of chime through the GIT B) Increasing the surface area of the GIT C) To breakdown aminoacids into smaller molecules D) None of the above 34. Which is recommended for acute cyanide poisoning A) Desferrioxamine B) Dimercaprol (BAL) C) Dicobalt edentate D) Pencillamine 40.Which of the following drugs increases the risk of digoxin toxicity A) Neomycin B) Hydrochlorthiazide C) Phenobarbital D) Oestradiol i41.Which of the following drugs is classified as an HMG CO-A reductase inhibitor A) Probucol B) Clofibrate C) Gemfibrozil D) Lovastatin .C) Vitamin D D) Vitamin B complex 36-Tricyclic antidepressants should be avoided in which of the following conditions A) Depressed patients with insomnia B) Closed angle glaucoma C) Diabetic peripheral neuropathy D) Nocturnal eneuresis 37. each of which contains 250 microgram of a drug A) 37.5 milligram B) 37500 microgram C) 375 milligram D) 3750 milligram 38.What is the weight used to make 1500 units.What will result if the distribution of drug drugs is slower than the process of biotranaformation and elimination A) Increase blood level of drug B) Decrease blood level of drug C) Synergism D) Failure to attain diffusion equilibrium 39. Which of the following is an indication for pancreatic enzyme supplements A) Cystic fibrosis B) Post pancreatectomy C) Post total gastrectomy D) All of the above 46.Which of the following is not indicated for use in children less than 12 years .Which of the following is a metabolic product of alcohol A) Acetaldehyde B) Formic acid C) 4.Which of the following is associated with less gastric side effects A)Difflunisal (Dolobid) B) Ibuprofen (brufen) C) Ketoprofen (Oruvail) D) Piroxicam (Feldene) 48.42.methyl pyrazole D) Pyridoxine 45.Which of the following drugs undergoes mared hydrolysis in the Gl tract A) Aspirin B) Pencillin G C) Paracetamol D) Hydrocortisone 43.Which of the following is found in vitamin B12 A) Magnessium B) Nickel C) Cobalt D) Iron 47.Which of the following is a contra indication of for Tricyclic antidepressant A) Insomnia B) Recent myocardial infarction C) Essential hypertension D) Nocturnal eneuresis 44. thyroxine B) Thyroglobulin C) Liothyronine D) Carbimazole .old A)Domperidone (Motilium) B) Doxycycline (Vibramycin) C) Chloramphenicol (Chloromycetin) D) Astemizole (Hismanal) 49.Which of the following is used as a plasma expander A) Sodium salts B) Starches C) Dextrans D) Calcium salts 53.Which of the following is used to treat hyperthyroidism A) L.Which of the following is TRUE about ORS in severe diarhoea A) Sugar and amino acids inhibits sodium and water reabsorption B) ORS includes sodium acetate and calcium C) ORS is the treatment of choice in children with diarhoea D) All of the above 52.Which of the following is NOT naturally occurring A) Oestradiol B) Diethylstilbesterol C) Oestrone D) Ethinyl oestradiol 50.Which of the following is not used as a vehicle for injections A) Peanut oil B) Cotton seed oil C) Corn oil D) Theobroma oil i51. Which of the following prokinetic drug is a dopamine receptor antagonist A) Metoclopramide B) Bethanechol C) Cisapride D) Buscopan 56.Which of the following CANNOT be used as a prophylactic for migraine A) Pizotifen B) Propanolol C) Methylsergide D) Dihydroergotamine 59.Which of the following drugs is indicated for the treatment of Attention of Deficit disorders in children A) Pseudoephedrine B) Dexamphetamine C) Venlafaxine D) Phenytoin 60.Which one the following is not an essential amino acid A) Threonine B) Glutamine C) Tryptophan D) Methionine .54.Which of the following stimulates hepatic microsomal enzymes A) Phenobarbitone B) Mannitol C) Urea D) None of the above 58.Which of the following statements is correct about chlorhexidine alcoholic solution A) Chlorhexidine will disinfect the hands if allowed to dry B) It is most suitable for disinfection of medical appliances C) It is essential to use it on the skin before venepuncture D) It provides the best treatment for impertigo 57.Which of the following is used to treat paracetamol overdose A) Acetylcysteine B) Methylene blue C) Pyridoxine D) Methylprednisolone 55. can be toxic when MAO.Penicillins are believed to exert their antibacterial effect by which of the following mechanisms A) Detergent effect on the bacterial cell membrane B) Inhibition of bacterial cell wall synthesis C) Inhibition of protein synthesis D) Steric hindrance of membrane amino acids 66.Which statement is true about Otitis media treatment A) Local treatment is more effective than systemic one B) Ear drops containing local anasethetic are of great value in the management of pain C) Systemic antibiotic is needed when bacterial involvement is proved D) Oral antibiotic use as a prophylactic measure is not indicated for recurrent otitis media 63.i61.Which of the following Over the Counter (OTC) medications has a dangerous drug interactions with Monoamine Oxidase Inhibitors A) Chlorpheniramine maleate B) Paracetamol C) Pseudoephedrine D) Vitamin C 62.Which substance commonly found in fermented food. the one that posseses the least sedating action is A) Diazepam (Valium) B) Buspirone (Buspar) C) Meprobamate (Equanil) D) Chlordiazepoxide ( Libirium) E) Oxazepam (Serax) 65.Which of the following antagonizes the actions of sulphonamides .Of the following anxiolytic agents.I are used A) Phenylalanine B) Tyramine C) Histidine D) None of the above 64. Which of the following drugs is indicated for the treatment of primary nocturnal eneuresis A) Ritordine (Yutopar) B) Desmopressin acetate (DDAVP) C) Metrolazone (Zaroxolyn) D) amiloride (Midamor) 68.amino benzoic acid 67.Which of the following oral hypoglyceamic drug has the longest serum half life A) Acetohexamide (Dymelor) B) Chlorpropamide (Diabinese) C) Glyburide ( Diabeta) D) Tolbutamide (Orinase) 70.A) Streptomycin B) Penicillin G C) Morphine D) Para.the thiazide diuretics decrease the excretion of A) sodium B) Urea C) Uric acid D) Bicarbonate 69.Diclofenac sodium (Voltaren) is most similar in action to A) Buspirone (Buspar) B) Dicyclomine ( Bentyl) C) Retoprofen (Orudis) D) Mecamylamine (Inversine) i71.Which of the following is not progestin A) Mestranol B) Nor-ethindrone C) Ethynordiol diacetate D) Levonergestrel . The most potent H2 receptor antagonist A) Omeprazole B) Sucralfate C) Famotidine D) Metoclopramide .All of the following are bacterial infections Except A) Cholera B) Plague C) Rabies D) Pertussis i74.The local anaesthetic most commonly used in OTC burn remedies is A) Benzocaine B) butamben picrate C) Lidocaine D) Phenol E) Tetracaine i76.Which of the following statements conserning Bisacodyl is NOT true A) Laxative action occurs with 6 hours after oral administration B) Tablets should be administered with milk to avoid gastric irritation C) Action of suppositories occurs within 1 hour after insertion D) Tablets should be swallowed whole i75.Agents useful in the treatment of bronchial asthma usually A) Block both alpha and beta adrenergic receptors B) Stimulate alpha receptors but block beta receptor C) Stimulate beta receptors but block alpha receptors D) Stimulate alpha and/ or beta receptors i73.i72.Methylcellulose and similar agents are used in ophthalmic solutions to A) Increase drop size B) Increase ocular contact time C) Reduce inflammation of the eye D) Reduce drop size i77. Zollinger.B&D i83.i78.The aminoglycoside most likely to remain a useful therapeutic agent in the event of resistance to Gentamicin A)Streptomycin B) Neomycin C) Amikacin D) Cephalosporin i82.Ellison syndrome is the result of adenomas in the A) Gallbladder B) Liver C) Stomach D) Pancreas E) A.Haloperidol is classified structurally as a A) Benzodiazepine B) Butyrophenone C) Phenothiazine D) Tricyclic E) Malonylurea i80.In Examining the patient.Which second generation cephalosporin is available as a parenteral and oral medication A) Cefuroxime B) Cephalexin C) Ceclor D) Cefonicid i79.Chronic treatment of rheumatoid arthritis with indomethacin requires care because indomethacin A) Is an anti-inflammatory steroid B) Cause headaches in some patiets C) Inhibits the action of prostaglandins D) Causes tachycardia i81. the physician notes that the patient complains polydepsia refers A) Excessive Urination . effects of lsotretinoin(Roaccutane) include A) Dermatological reactions B) Depression C) Teratogenicity D) All of the above i89.All of the following drugs are used to treat patients with open angle glaucoma EXCEPT A) Carbachol B) Atropine C) Dipiverine D) Betaxolol i86.Which of the following antifungal agents is NOT effective against Candida A) Nystatin B) Clotrimazole C) Tolnaftate D) Miconazole i87.Side.Which of the following should NOT be administered to a patient being treated with narrow angle glaucoma A) Dipiverine B) Pilocarpine C) Carbachol D) Homatropine i85.Which of the following is the shortest acting Mydriatic A) Atropine .B) Excessive appetite C) Excessive Weight gain D) Excessive thirst E) B&C i84.Which of the following sulphonylureas has the longest half life A) Tolbutamide B) Glibenclamide C) Tolazamide D) Chlorpropamide i88. Which of the following drugs is NOT associated with increased prolactin secretion A) Chlorpromazine B) Metoclopramide C) Bromcriptine D) Methyldopa i93. Vomitting B) Constipation C) High body temperature D) Bronchospasm i95.B) Pilocarpine C) Tropicamide D) A.Prolactin inhibiting factor is A) Dopamine B) Thyrotropin C) Somatropin D) Corticotropin i92.Which of the following is the first diagnostic symptom of Digoxin overdose A) Anorexia. Nausea.Tinea infections are caused by A) Virus B) Fungus C) Gram-positive bacteria D) None of the above i91.The action of Digoxin is enhanced by a level of which of the following ion A) Sodium B) Calcium C) Magnessium D) Potassium i94.B&C i90.Which of the following is a blood platelet adhesion inhibitor A) Dipyridamole B) Nitrofurantoin . The two major properties of drugs that are usually modified by complexation are A)Odor and tast B) Tast and solubility C) Chemical structure and solubility D)Chemical structure and stability E) Stability and solubility i99.Lidocaine is used as a A) General anesthesia B) Antipyretic C) Antiarrythmic D) Pre.The principal toxic effect of Heparin is A) Bronchospasm B) Chills C) Hair loss D) Haemorrhage i98.anaesthetic i97.Sucralfate is used to trrat A) Peptic ulcers B) Carcinoma C) Calcium depletion D) Obesity .C) Dextropropoxyphene D) Imipramine i96.PH is A) Not temperature dependent B) A measure of acidity C) The same as POH D) igh for acids E) None of the a bove i100. com 1 .prometric-questions.www. www.com 2 .prometric-questions. 140 Exam model 9 ....... 205 Answer of Exam model 10 ........prometric-questions.............................................................................................................................................................................. 157 Exam model 10 ...................................................................................................................................... 24 Exam model 3 ...... 200 Answer of Exam model 5 ....... 86 Exam model 6 ............................................................................................................................................................................................................................................................................................................ 203 Answer of Exam model 8 .......................................... 198 Answer of Exam model 3 ............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 181 Answer of Exam model 1 ........................... 66 Exam model 5 .................................................... 207 www....................... 201 Answer of Exam model 6 ....................... 174 Exam model 11 ................. 44 Exam model 4 ........................................................................................................................................................com 3 ..................................................... 4 Exam model 2 ..........................................................................................................................................................................................................................Table of Contents Exam model 1 ........................................................................................................................................... 202 Answer of Exam model 7 ...................................... 199 Answer of Exam model 4 .................................................. 197 Answer of Exam model 2 ............................................................................ 206 Answer of Exam model 11 ....................................................... 204 Answer of Exam model 9 ................ 123 Exam model 8 ............................................................................................ 106 Exam model 7 ................................................................................................. Controlled drug in the body depend on a.Ephedrine d.Toxic dose * therapeutic dose e.therapeutic dose c.prometric-questions.150 mg / day b.Toxic dose + therapeutic dose b.Therapeutic index is a.None of the above 4.Kill all worms c.Both a & b e.Both b & c e.PH b.Maximum dose of captopril is a.Hydrocortisone c.Saline e.Enzymatic reaction c.Exam model 1 1.Drug of choice for nematode d.When hypertension occur c.Generic name of biltiricide b.None of the above www.All of the above 5.All of the above 3.At cardiac shock the first drug of choice is a.400 mg / day d.com 4 .Both a & b e.Body fluid interaction d.Praziquantel is a.Epinephrine b.Toxic dose .None of them 2.Toxic dose / therapeutic dose d. com 5 .All of the above e.Antibiotic d.Insulin which can be given intravenously is a.6.Metoprolol d.Antiplatelet c.Anticoagulant b.Anticholinergic e.Normal saline e.Labetalol 7.All are cardio selective B bloker except a.Acebutalol e.Atenolol b.Esmolol c.Propranolol d.Ticlopidine is a.Ephedrine b.30/70 type c.Lomefloxacin www.Lidocaine c.NPH type d.Non of the above 10abcde- Drug is used for leishmania Sodium stiboglyconante Sodium cromoglyconate Mebendazole Metronidazole Nifuortimox 11All these drug are anti bacterial except a.prometric-questions.Hydrocortisone 9.Regular type b.Cardiac arrest could be managed by the following except a.Antifibrinolytic 8. enoxacin c.com 6 .bcde- Cefeprazone Amoxicillin Streptomycin Zalacitabine 12abcde- All these are natural estrogen except Mestranol Estrone Estriol Estradiol Non of them 13abcde- Co trimoxazole contains Trimethoprime and Sulphamethoxazole Trimethoprime and Sulphadiazine Trimethoprime and Sulphonyl urea Trimethoprime and Sulphauracil Trimethoprime and salbutamol 14abcde- Which of the following has vasodilator effect : Nicotine Cholestramine Urokinase Vitamine A Calcium 15abcde- One of the following is not for epilepsy Clonazepam Phenytoin Primidone Imipramine Depakine 16One of the following is not from quinolone group a.prometric-questions.quinine www.Naldixic acid b. d.com 7 .norfloxacin e.prometric-questions.ciprofloxacin 17abcde- one of the following should be avoided in pregnancy vitamin A calcium misoprostol ( cytotic ) paracetamol ampicillin 18abcde- All of these can be used for treatment of leprosy except Dapson Rifampin Clofazinine INH None of the above 19abcde- Sumatriptan is used for Hypertension Treatment of migraine Angina pectoris Control epilepsy Epilepsy 20abcde- Which of the following is enzyme inducer Rifampicin Cimetidine Chloramphinicol Vit C Omeprazle 21abcde- All of the following for prophylaxis of asthma except Ketotifen Nedocromil sodium Sodium cromoglycate Salbutamol None of the above www. com 8 .None of the above 23abcde- All of the following are controlled drugs except Rivotril Epanutin Stesolid Diazepam None of the above 24abcde- All these drugs are anti viral except Amantadine Zidovudine Acyclovir Alurin Gancyclovir 25Which of the following symptoms does not occur with morphine a.Respiratory depression e.Vomiting c.propyl uracil e.tadenan c.Carbimazole b.throxine sodium d.Diarrhea b.Loratidine b.22All of the following is NSAH ( non sedating antihistaminic ) except a.Azatadine e.prometric-questions.Astemizol d.Cetrizine c.Constipation d.potassium iodide www.Addiction 26Which one of the following is the drug of choice for myxodema ( hypothrodism ) a. prometric-questions.27abcde- Which of these drugs is not used for acute pain Naproxine Colichicine Codeine Prednisolone Keorelac 28abcde- Benzyl peroxide is alcohol treatment for Rheumatic pain Angina pectoris Acne vulgaris Dysmenorrheal Diabetes insipidus 29abcde- Vitamin A daily dose for therapy 20 000 IU 100 000 .com 9 .200 000 IU 20 000 .100 000 IU 15 000 IU 10 000 IU 30abcde- Vitamin A daily dose correction of deficiency 15 000 IU 20 000 IU 50 000 IU 100 000 IU 500 000 IU 31abcde- The drug of choice of treatment of amoeba Chloramphinicol Gentamycin Tetracycline Metronidazole Mebendazole 32To prevent more absorption of the toxic drug we use a.Water www. Vitamin K d.bcde- Saline Sodium salt Potassium salt Activated charcoal 33abcde- Hepatitis vaccine dose Once per year Twice per year Three per year Four time per year None of them 34abcde- Which one is OTC drug Analgesics Warfarin Ciprofloxacin Insulin Glibinclamide 35Anticoagulant effect of warfarin is decreased by the use of the following except a.Directly proportional to the rate of absorption www.Rifampicin b.prometric-questions.All of them e.None of them 36abcde- One of the following is given once daily Amorphous insulin Protamine Zinc insulin Regular insulin Both b&c All of the bove 37The steady state concentration of the drug in the plasma is a.com 11 .Aspirin c. Synthesis of iron b.Quinidine b.Synthesis of coagulation factor by hepatic cell www.prometric-questions.Sotalol e.Digoxine c.Verapamil d.bcde- Indirectly proportional to the rate of absorption Directly proportional to the rate of elimination Indirectly proportional to the rate of elimination Directly proportional to the rate of distribution 38abcde- All these are anti coagulant except Warfarine Ancord Heparin Dalteparin Dipyridamole 39abcde- The following are antiplatelet except Dipyridamole Ticlopidne Streptokinase Aspirin Clobidogrel 40abcde- Ferrogard is Ferrous citrate Ferrous sulfate Ferrous gluconate Ferrous fumarate Ferric sulfate 41Procainamide interfere with sodium channel activity the same as a.Amlodipine 42What is the function of vitamin K a.com 11 . C.Synthesis of vitamin B12 e.Synthesis of histamine 43abcde- Thiazide derivative cause all of the following except Hyponatremia Hyperglycemia Hypokalemia Hyperuricemia Hypernatremia 44Treatment with anti arrhythmic drug depend on all of the following EXCEPT a.V (not by mouth )because Not stable in gastric PH Eliminated very quickly Causes nausea and vomiting if taken orally Needed large dose orally None of the above 47Amiloride treatment can cause a.Patient sex c.N.c.Type of medication b.Hyperkalemia c.Diagnosis e.prometric-questions.com 12 .Synthesis of prostaglandin d.Pharmacokinetic 45abcde- Elimination of digoxine is mainly by Kidney Liver Skin Both a & b All of the above 46abcde- Dobutamine is given I.S disturbance b.Hypokalemia www.Period of medication d. com 13 .d.Both a & b e.prometric-questions.None of the above 48abcde- Drug can cause problem if taken as an OTC Warfarine Captopril Chlorothiazide Rifampicin Gemfibrozil 49abcde- Drug physical dependence As same as drug abuse Less than drug abuse More than drug abuse A or b A or d 50abcde- Thiazide diuretics include Chlorothiazide Hydrochlorothiazide Indepamide Both a & b All of the above 51abcde- QID Three time daily Four time daily Twice daily Every 6 hour Every 8 hour 52abcde- Amphotricin Antifungal that acts parenterally only Antifungal that acts orally only Antifungal that acts parenterally and oral Imidazole group antifungal All of the above www. com 14 .53abcde- Grisofulvin Antifungal that acts parenterally only Antifungal that acts orally only Antifungal that acts parenterally and oral Imidazole group antifungal All of the above 54abcde- Miconazole Antifungal that acts systemic only Antifungal that acts locally only Antifungal that acts local and systemic Imidazole group antifungal Both c & d 55abcde- Gemifibrozil used for treatment of Hypolipidemia Hyperlipidemia Hypotension Hypertension None of the above 56abcde- All are antimetabolite except Methotrexate Flurouracil Cytrabine Azathiopine Cyclophosphamide 57abcde- Cefaclor 1 generation cephalosporin 2nd generation cephalosporin 3rd generation cephalosporin 4th generation cephalosporin 5th generation cephalosporin st 58Which aminoglycoside antibiotic can be taken orally a.prometric-questions.Gentamycin www. Amikacin d.prometric-questions.D.com 15 .E.Vitamin A.Neomycin c.Kanamycin 60abcde- Which of the following is not from tetracycline group Minocycline Doxycycline Demeclocycline Clindamycin None of them 61abcde- Which of the following is not calcium channel blocker Verapamil Dilitiazem Amlodipine Cinnarizine Nifidepine 62abcde- Mesalazine ( ascal ) is a treatment and maintenance of Ulcerative colitis Bronchial asthma Primary dysmenorrheal Secondary epilepsy Diabetes mellitus 63Lipid soluble vitamin a.bcde- Neomycin Amikacin Tobramycin Kanamycin 59Tecloplanin antibiotic effect on gram positive bacteria similar to a.C b.K www.E.D.Tobramycin e.Vancomycin b.Vitamin A. K. except I.E.prometric-questions.C d.B.B e.C.c.K.H Rifampin Cycloserine Cyclosporine None of the above 66abcde- All these drugs are anticholenergic except Ipratropium bromide Atropine sulphate Benzotropine mesylate Hyoscine N butyl bromide Dobutamine 67abcde- All these drugs are anti bacterial except Zalacitabine Cefprozil Lomefloxacin Cefpodoxime Clarithromycin 68abcd- There is one drug used for HIV Zalacitabine Finasteride Cefaprozil Enoxacin www.D.Vitamin A.Vitamin A.com 16 .B 64abcde- Imipenem ( carbepenem ) Beta lactam antibiotic Cephalosporin Quinolone Macrolides aminoglycoside 65abcde- All these medication used in T.N.D.Vitamin A. Fluconazole d.Sulphamethoxazole 71abcde- All these can be used in leprosy except Dapson Rifampicin Clofazimine I.N.e.prometric-questions.H None of the above 72abcde- Timolol Non selective for glaucoma Selective antihypertensive None Selective antihypertensive Selective for asthma Selective for glaucoma 73abcde- Acebutalol Non selective for glaucoma Selective antihypertensive None Selective antihypertensive Selective for asthma Selective for glaucoma www.Cefuroxime e.Itraconazole c.Cefixime b.Ampicillin 69abcde- Suprax® is Cefixime Itraconazole Fluconazole Cefuroxime Sulphamethoxazole 70Which one is sporanox® a.com 17 . com 18 .74abcde- Labetalol Non selective for glaucoma Selective antihypertensive None Selective antihypertensive Selective for asthma Selective for glaucoma 75abcde- Betaxolol Non selective for glaucoma Selective antihypertensive None Selective antihypertensive Selective for asthma Selective for glaucoma 76abcde- Which one is not aminoglycoside antibiotic Netilimycin Lymecyclin Kanamycin Tobramycin Gentamycin 77abcde- Betahistine HCL Antihistaminic Minneare disease Analgesic Both a & b All of the above 78abcde- Which one is not 5HT-3 antagonist Tropisetron Ondasetron Domperidone Granisetron None of the above 79Which is not oral anticoagulant a.Warfarin www.prometric-questions. T.5 mg in 8 hour 7.5 mg in 24 hour 4 mg in 24 hour 4 mg in 12 hour 82abcde- The duration of treatment of T.5 mg in 4 hour 7.prometric-questions.Z) Act peripherally Has antiemetic effect Both a & b All of the above 84Which of the following is contraindicated in pregnancy a.B by CTX is One day One week One month Six months None of the above 83abcde- Metoclopramide is dopamine antagonist Act centrally by blocking chemoreceptor trigger zone (C.Ethambutol c.com 19 .Chloropheneramine www.bcde- Enoeparine Phenidione Nicoumalone None of them 80abcde- Which is correct about diazepam Can cause muscle spasm Is taken I.Sucralfate b.M only Derivative form morphine Not used for long time Sedative and hypnotic 81abcde- Maximum dose of paracetamol is 7. Methyl dopa 89abcd- Pneumocysis carini pneumonia (P.Captopril c.Enalapril b.com 21 .d.Propranolol d.C.Ciprofloxacin e.prometric-questions.Amoxicillin 85abcde- Bioavailability of the drug is Rate of absorption Extent of absorption Rate & Extent of absorption Rate & extent of distribution None of the above 86abcde- Example of drug induced hepatoxicity Paracetamol Ketoconazole Rifampicin Quinidine All of them 87abcde- Terbinafine is used topical for Eczema Fungal infection Candida All of them None them 88Which of the following is not contraindicated in pregnancy a.P) Virus Bacteria Parasite Mycobacteria www.Nitroprusside e. Mivacurim 92abcde- All of these are broad spectrum cephalosporin except Cefipime Cefopodoxime Ceftriaxone Cefotaxime None of them 93abcde- Which one of these is not mucolytic Bromhexine Carbocycistiene Ambroxol Guiaphensin Dextromethorphan 94abcde- Which one is antiplatelet Ticlopidine Desfluran Warfarin Heparin Urokinase www.Cefaprozil b.e.Helminthes 90abcde- Which one of these is not antibiotic Erythromycin Cefaprozil Sulphamefinide Levofloxacin Finasteride 91Which of the following is used in Benign prostate hyperplasia (BPHP) a.Levofloxacin d.prometric-questions.Finasteride e.com 21 .Sulphamefinide c. Anti dote of heparin a.Acetyl cystine c.Protamine sulfate www.Naloxone e.Vitamin K d.com 22 .Protamine sulfate b.prometric-questions.95abcde- All of these are anti-neoplastics except Tenoposide Pentostatin Amlodipine Aldesleukin None of the above 96abcde- Potassium supplement therapy must not be given with Triametrene Aspirin Paracetamol Piroxicam Fuoresimide 97abcde- Misoprostol (cytotic ) inhibit gastric acidity by Proton pump Inhibitor H2 blocker Protect mucosa Both a & b All of the above 98abcde- Drugs induce nephrotoxicity Aminglycoside Sulphonamide Penicillin Both a and b All of the above 99.Desferroxamine 100Antidote of paracetamol a. bcde- Acetyl cystine Vitamin K Naloxone Desferroxamine www.com 23 .prometric-questions. Poor patient compliance means a.Fluoxetine ( Prozac ) is a.Generic name of vitamine B1 is a.All of the above 5.Spironolactone and digoxine e.Thiamine b.Patient not take medication neither in proper time nor proper dose b.Riboflavin c.Niacin d.Insulin and INH c.Warfarin and aspirin b.Both a & b e.All of the above 2.Both a & b e.Antidepressant d.Act as proton pump inhibitor b.The rate of absorption is higher than that of elimination d.SSRI b.Block the hydrogen potassium ATP enzyme system d.Examples of drug drug interaction a.prometric-questions.Block hydrogen receptor c.Selective serotonin reuptake inhibitor c.Omeprazole a.com 24 .Cyanocobolamin www.All of the above 3.Pyridoxine e.Exam model 2 1.Both a & b e.Captopril and potassium sparing diuretic d.Both a & c 4.Patient take medication not under physician advice c. Pyridoxine e.Thiamine b.P component except a.Mennengococcal polysaccharide – Measles – rubella d.Niacin d.6.com 25 .Cyanocobolamin 7.R vaccine is a.Riboflavin c.M.Thiamine b.Niacin d.Cyanocobolamin 9.Mennengococcal polysaccharide – mumps – rabies 11.Generic name of vitamine B12 is a.g methyl cellulose to www.prometric-questions.Pyridoxine e.All of these are calamine lactate B.Thiamine b.Niacin d.Measles – mumps – rubella e.Riboflavin c.Generic name of vitamine B6 is a.Calamine c.Sodium citrate e.Zinc oxide b.Cyanocobolamin 8.The instruction for patient taking METAMUCIL or any other bulk forming laxative ( e.Measles – mumps – rabies c.Riboflavin c.Pyridoxine e.Mennengococcal polysaccharide – mumps – rubella b.M.Sodium sulphate d.Generic name of vitamine B2 is a.Bentonite 10. Pravastatin e.prometric-questions.Administration of charcoal c.com 26 .a.All of the above 14.Atorvastatin d.Both b & c 15.All of the above 12.Thiazide diuretic www.Both a & b e.E.All of the above 13.Gastric ad duodenal ulcer b.Fluvastatin c.Streptococcous pneumonia b.Source of human insulin a.Clavulanate penicillin b.Zantac contain a.Thiabendazole is a.Influenza A c.Both a & b e. coli by recombinant DNA technology d.Cytotic is used for a.Adequate fluid intake should be maintained to avoid intestinal obstruction b.The following is ( are ) HMG-CoA reductase inhibitor a.Cefuroxime c.Streptomycin e.Antagonize by diuretic d.Chloramphinicol 16.Both a & b e.Contraindicated in pregnancy c.Upper respiratory tract infection d.Cefaclor d.Simvastatin b. com 27 .Potent diuretic c.Nitroprusside sodium is a.Potent vasodilator b. LDL and triglyceride 19.Theophyllin c.Increase HDL and triglyceride b.It is stable in basic media www.NaCL + K citrate + Na citrate + glucose e.It is taken by oral route only c.Increase HDL .Increase HDL and LDL d.Amikacin b.Potent vasoconstrictor d.One of the following is true for flucloxacillin a.Drugs needs monitoring their serum level a.Gemifibrozil a.NaCL + K chloride + NaHCO3 + citric acid 18.Digoxin e.It is inactivated by penicillinase enzyme b.Sodium chloride + potassium chloride + glucose c.prometric-questions.Sodium chloride + potassium citrate + sodium citrate d.Warfarin d.All of the above 21.Increase HDL and decrease triglyceride c.Oral rehydration solution contain a.Sodium chloride + potassium chloride + sodium citrate b.Increase LDL and triglyceride e.bcde- Loop diuretic Potassium sparing diuretic All of them None of them 17.Anti malaria 20.Anti arrhythmic agent e. Increase conversion of vitamin K to its active form c.T.Both a and b e.U.d.All of the above e.Increase formation of clotting factor b.Converting angiotensin I to vasoconstrictor angiotensin II c.Converting angiotensin II to vasodilator angiotensin I e.U.It is belong cephalosporin group 22.Used for malaria c.Converting angiotensin II to vasoconstrictor angiotensin I b.decrease conversion of vitamin K to its active form d.Both a & b e.Parasitic infection 24.Quinidine sulfate is a.All of the above 26.Praziquentel used for bilharziasis a.GIT infection e.Converting angiotensin I to vasodilator angiotensin II d.Has trade name Biltricide d.None of the above 25.None of the above www.prometric-questions.ACE mechanisms a.Causes loss of intracellular calcium of worms b.com 28 .I c.Vitamin K a.Antiarrythemic b.Both a & c 23.R.Anti hypertensive d.It is better absorbed than cloxacillin e.T b.Viral infection d.Nitrofuranton is indicated for a.Anti malarial c. Ipeca is emetic agent which induce emesis through a.com 29 .27.Both a & b e.Stimulation of stomach b.Cause bradycardia d.Imidazole group d.Stimulation of the CTZ in C.Hypokalemia d.Anti amebiasis b.All are side effects of thiazide except a.Hyperuricemia e.Both a & c 29.N.All of the above e.Itraconazole is a.Five Dose 31.Theophylline is a.B2 agonist c.N.All of the above 30.Single Dose b.B1 antagonist e.None of the above 32.Anaphylactic reaction is treated by a.Anti fungal c.Schedule for immunization for HBV is a.Hyperglycemia c.Bronchodilator b.Two Dose c.Epinephrine www.S c.Three Dose d.S d.Suppression of the CTZ in C.Hypercalcemia 28.prometric-questions.Four Dose e.Hypernatermia b. Flour 35.Minoxidil is monitored by the following parameters except a.Triazole a.Trade name of amphotricin B d.Chloride e.Pulse rate www.short acting anti histaminic c.Acetate c.Urine flow b.Paracetamol poisoning b.Caustic substance ingestion e.prometric-questions.Antibacterial 37.Unconsciousness patient 34.com 31 .none of the above 36.Antifugal b.bcde- Human albunin Cimetidine Hydrocortisone atenolol 33.Seizers c.Long acting anti histaminic b.Blood pressure c.sedating antihistaminic e.is similar to chloropheneramine maleate d.All of the following is anion except a.CNS depression d.Phosphate b.Sodium d.Emesis is not indicated for the following EXCEPT a.Its nystatin e.Trade name of clotrimazole c.Astemazole a. com 31 .Indication of allopurinol a.Example of non sedating antihistaminic a.Loratadine b.None of the above 38.Used in treatment of gastric and duodenal ulcer b.Influenza symptoms d.Which of the following is not true about tetracycline a.Used for hepatitis c.Terfenadrine e.Anticoagulant therapy b.Ceterizine d.Chicken box c.All of them e.None of them www.Dysmenorrheal e.Aspirin is recommended with a.Used in influenza d.Prophylaxis of gout b.All of the above 42.Famotidne is H2 receptor antagonist a.Broad spectrum bacteriocidal c.Inhibit protein synthesis at 30 S ribosomal subunit d.prometric-questions.Treatment of uric acid and Ca oxalate renal stone c.All of the above 41.Astemazole c.Trade name is zyloric d.Body weight e.Both a & c e.d.Hypertension 39.Used for acne e.interfere with Cause calcium deposition in bone and teeth 40.Broad spectrum bacteriostatic b. Drug consider potassium sparing diuretic a.Response to diet therapy alone d.prometric-questions.Ototoxicity b.Penicillin e.Both a and b are correct 47.No increase of sulphonyl urea requirement 45.Nor floxacin c.Inhibit conversion of angiotensin I to II b.Amiloride c.43.Used in patient suffer from heart failure d.Lack of response to sulphonyl urea c.Acetazolamide a.Nephrotoxicity c.The following is / are quinolone a.Type II diabetes is characterized by a.Slowly increase of sulphonyl urea requirement e.com 32 .All of the above 46.Use in treatment of glaucoma www.Both a and c e.Streptomycin d.Triametrine b.Side effect of aminoglycoside a.Effective hypotensive drug c.The action of captopril a.Both a and b e.All of the above 44.Lack response to insulin b.Maximum dose is 150 mg/day e.Spironolactone d.Ciprofloxacin b.Hepatotoxicity d.All of the above 48. Anti coagulant c.All of these you can dispense to patient without prescription except a.com 33 .Tegretol c.Antidepressant d.Trade name of pindolol a.Vitamin C b.Inderal® e.Vitamin C 51.Rifampicin e.Hypotensive agent 52.Bisacodyl e.Metronidazole d.Losec® c.Trade name of baclofen a.Anti malarial b.bcde- Inhibit carbonic anhydrase enzyme Reduce intra ocular pressure It is diuretic All of the above 49.Aspirin b.prometric-questions.Malox d.Visken® b.All of them 50.Visken® b.Lioresal® d.Cimitidine c.None of them 53.Hypoglycemic agent e.Acetohexamide is a.Which one induces metabolism of other medication a.Losec® www. Prescription only medicine b.What is the meaning of G6PD a.What is the meaning of ECG a.M a.What is the meaning of P.Four time daily 58.Lioresal® d.prometric-questions.Electrocardiogram c.Losec® c.Twice daily d.Glucose 6 phosphate dehydrogenase e.Four time daily 57.Twice daily d.Trade name of omeprazole a.Prescription only medicine b.Prescription only medicine b.What is the meaning of BID a.Prescription only medicine b.Electrocardiogram c.Four time daily 56.Glucose 6 phosphate dehydrogenase e.None of them 55.None of them 54.c.Twice daily d.Lioresal ® d.Visken ® b.Glucose 6 phosphate dehydrogenase e.Inderal ® e.com 34 .Inderal ® e.Electrocardiogram c.Twice daily d.O.Glucose 6 phosphate dehydrogenase www.Electrocardiogram c. 5 gm b.All of the above 62.25 gm d.Which of the following has no vasodilating effect www.225 gm e.gm NaCl a.Tetracycline e.45 gm c.treatment of parkinsonism d.Hypoglycemic agent 64.Antidepressant c.combined with Benzerzide c.2.Which one of these is pro drug a.Lisinopril e.e.Captopril b.both a and c e.Specific serotonin reuptake inhibitor (SSRI) are used as a.prometric-questions.9 % contain …….500 ml of normal saline 0.Antiemetic e.Ampicillin b.4.com 35 .Four time daily 59.Levodopa is a.combined with Carbidopa b.Pivampicillin d.All of the above 60.Erythromycin c.ACE inhibitors are a..Fosinopril d.Enalapril c.all of the above 63..Antihypertensive d.45 gm 61.Anti histaminic b.. Psoriasis d.Cotrimoxazole d.INH b.Pyrazinamide e.Acne e.350 mg / day d.150 mg / day b.Antiepileptic c.prometric-questions.250 mg / day c.Drug contraindicated in pregnancy a.Influenza A www.150 mg / 12 hour e.Antiviral b.Ethambutol c.All of the above 67.Hypertension c.com 36 .Calcipotriol is indicated for a.Calcium supplement b.Hyperthyroidism 68.250 – 350 / 12 hour 69. treatment a.B.NSAIDs b.Rifampicin d.The following is used in T.Mesoprostol e.Amantadine is used for the following except a.Maximum dose of captopril is a.abcde- Enalapril Methyl dopa Hydralazine Prazosin Verapamil 65.All of them 66. Propranolol c.Bisoprolol c.Unionized & hydrophilic d.Drug to pass B.Saline solution e.Metoprolol e.At cardiac shock (arrest ) the drug of choice is a.Hydrocortisone d.c.Unionized & lipophylic b.All of the following are anti parkinsonism metabolite ( cytotoxic ) except a.Amantadine b.Influenza c.Selegiline www.Influenza B e.Any of them 74.Example of cardioselective B blocker a.Herpes zoster d.Amtiparkinsonism d.com 37 .Hepatitis B b.B.Atenolol b.Ringer solution 72.None of them 70.Esmolol d.Varicella 71.Rikettsia e.prometric-questions.Ionized & lipophylic e.All of the above 73.B a.Levodopa c.Ionized & hydrophilic c.Epinephrine b.All are viral infection except a. Ondasetron c.None of the above 77.Stimulation of chemo trigger zone c.Triamicrolon d.Cytrabine d.prometric-questions.Gram negative bacteria c.Gram positive bacteria b.None of the above 79.Hydroatropine c.Inhibition of chemo trigger zone www.All of the following are anti metabolite ( cytotoxic ) except a.All those are corticosteroid except a.All of the following are anti cholinergic except a.Dexamethasone 78.d.com 38 .Predinsolon b.Stimulation of stomach b.Cyclophosphamide b.Flurouracil e.Butropium bromide e.Upper respiratory tract infections are treated sometimes with antibiotic.Bromocriptine e.Ipratropium bromide d.Mercaptopurine 76.Atropine sulphate b.Beclomethasone e. the recommended micro organisms for which you suggest an antibiotics are a.Ipecac induce vomiting through a.Mixed bacteria d.Apomorphine 75.Any of the above e.Methotrexate c. All of the following are used for T.Cyclosporine 81.side effect of insulin are a.INH b.Fat atrophy at site of injection d.sulphonyl urea c.Any of them e.Cycloserine c.hypersensitivity c.When newly married don’t want children .type II diabetes advised to use a.both a and b e.type I diabetes advised to use a.local reaction b.diet regimen only b.None of them 82.Send the wife to the family doctor b. the contraception should be arranged as follow a.both a and b e.d.Avoid obstruction during fertility period c.All of the above www.Rifampicin d.all of them 84. except a.metformine d.insulin b.Both a and c 80.Use the calendar d.all of the above 83.com 39 .B.glibenclamide c.Both a and b e.prometric-questions.insulin d.Ethambutol e. paromomycin d.OTC include a.release in the stomach d.Thyoxine c.Pass the stomach and intestine c.streptomycin c.prometric-questions.None of the above 88.neomycin sulphate b.com 41 .increasment of metabolism and reduction of response d.Simple analgesic b.the only amino glycoside antibiotic can be taken orally a.fluid retention b.hyperglycemia d.reduction of metabolism and response c.one of the following is main side effect of insulin a.Theophylline d.e.all of the above e.hypoglycemia c.both a and b e.All of these are true for levodopa except www.Both a and b e.all of the above 87.None of the above 90.None of the above 85.All of the above 89.Release in fundus of the stomach e.Enteric coated tablet a.chloramphenicol liver inhibitory effect include a.none of the above 86.reduction of metabolism and increasment of response e.increasment of metabolism and response b.Pass the stomach and release in the intestine b. All of the above 93.Addiction b.com 41 .90 – 110 % d.Morphine is similar to morpine in a.Ask if he is hypertensive d.If prescription contains inderal ® and the patient is wheezing a.B.Ask him if he asthmatic c.Slower in action d.Theophylline is a.prometric-questions.B barrier Effective in parkinsonism Stimulate dopamine release Combined with carbidopa 91.Both a and b e.All of the above 92.None of the above 94.Faster in action c.Constipation e.Miosis c.Not less than 100 % b.Call the doctor e.Not less than 90% c.Pentobarbital differ from Phenobarbital in a.Analgesic d.Anti cholinergic www.abcde- Precursor of dopa Don’t pass the B.None of the above 95.Bronchodilator b.Less than 80 % e.Give the medicine b.Longer duration b.The concentration of the drug on the expiry date should be a. Span c.Increase the metabolism and dose b.Tween b.None of the above 98.All of the above e.B2 agonist d.Surfactant not used orally a.Reduction the metabolism and increment dose e.U www.Both b and c 100-Zidovudine is used for a.Drug response when react to the receptor to give effect d.Increase the metabolism and reduction dose d.Pharmacokinetics is a.All of the above e.Effect of drug on the body c.Transformation drug from less lipid soluble to more lipid soluble c.Both a and b e.Transformation drug from less lipid soluble to least lipid soluble d.None of the above 97.P.None of the above 99.Theophylline dose in children a.c.All of the above e.prometric-questions.AIDS b.com 42 .Transformation drug from more lipid soluble to less lipid soluble b.None of the above 96.Biotransformation process is a.Decrease the metabolism and dose c.Effect of body on drug b.Na lauryl sulphate d. All of the above www.HIV d.Both a & c e.prometric-questions.c.com 43 . Amiloride d.prometric-questions.Praziquantel is a.Azithromycin c.Enoxacin e.Antihistaminic b.paracetamol d.Using ACE inhibitor c.warfarin e.Fuoresmide b.Bronchodilator c.Bumetanide e.None of the above 3.The following are quinolone antibiotic EXCEPT a.Non steroidal anti inflammatory drug d.Exam model 3 1.captopril b.There is contraindication in taking potassium contacting preparation with these cases EXCEPT a.Norfloxacin 2.Renal disease b.gemifibrozil c.One of these drugs is potentially harmful when taken with OTC drugs without medical consultation a.Acetazolamide 4.Ciprofloxacin b.Hypertension d.Chlorothalidone c.Using potassium diuretic www.Nalidixic acid d.Antibiotic e.Which of the following diuretic may cause hyperkalemia a.com 44 .amiloride 5. Magnesium sulphate 7.500 – 1000 mg / 4-6 hours daily 8.Claims for new drugs for hypertension concentrate on a.Calcium carbonate d.20 – 60 mg / 4-6 hours daily e.Streptokinase c.Ability to control blood pressure around the clock e.e.Sodium chloride b.Concerning levodopa all of the following statement are correct EXCEPT a.Ability to lower blood pressure within shorter time b.120 – 250 mg / 4-6 hours daily b.Potassium bicarbonate e.Sodium bicarbonate c.prometric-questions.com 45 .Ability to cause less rebound hypertension d.Is only effective in the prescience of dopamine producing neuron e.Urokinase www.Ability to lower high readings of blood pressure c.60 – 120 mg / 4-6 hours daily d.250 – 500 mg / 4-6 hours daily c.Does not cross the blood brain barrier c.The dose of paracetamol for 3 month children to one year old child is a.none of the above 10All of these are fibrinolytic drugs EXCEPT a.For metabolic acidosis one of these is given a.Muscle spasm 6.Causes increase dopamine output in parkinsonian brain d.Dipyridamole b.Is a precursor of dopamine b.It combined with carbidopa 9. one of the newest agent of the NSAIDs as they are more potent www.play an important role in energy metabolism d.paracetamole in dose of 1 × 500 mg tablet PRN c.all of the above 12abcde- all of these statement are true for amantadine EXCEPT trade name is symmetrical used in parkinsonism antiviral used in prophylaxis of influenza A virus used in prophylaxis of influenza B virus 13abcde- which one of the following is NOT corticosteroid triamiinolone ondasetron budesonide beclomethasone betamethasone 14abcde- the following are adverse effect of insulin EXCEPT hypoglycemia fluid retention hyperglycemia fat atrophy visual disturbance 15the safest drug for an elderly patient who suffering from osteoarthritis and peptic ulcer disease (PUD) a.prometric-questions.apirin as it the most established drug for this condition b.d.vital for normal body temperature c.Anistrplase e.com 46 .vital for normal growth and development b.Alteplase 11which of the following statement concerning thyroid hormone is correct a.both a and b e. antihypertensive therapy b.com 47 .vaccination 19when dispensing drug that cause allergic reaction such as penicillin and sulfonamide the pharmacist should a.oral contraceptive use d.frequent blood transfusion c.paracetamole in dose of 2 × 500 mg tablet on regular basis e.none of the above 20the best advice for the parent of a feverish child (41°C) is to suggest a.ask patient if he allergic to drug d.ask patient to avoid taking drug with milk c.ask patient to avoid certain dosage form of the drug e.general anesthesia e.indomethacin suppository to avoid gastric route 16abcde- itraconazole is anti amebiasis anti fungal from imidazole group anti malarial all of the above 17abcde- ondasetron HCL is used for hypertension prophylaxis of migraine headache angina pectoris emesis constipation 18malignant hypothermia ( a rare inherited muscle disorder ) a typical complication of a.prometric-questions. immediately www.ask patient to avoid taking drug with food b.take him to the hospital which is 30 minute drive .d. to give 1 gm paracetamole immediately d.b.sodium cromoglycate d.loratadine e.cetrizine c.wait for 2 hour and if temperature does not come down go to the hospital c.terfenadine d.ketotifen b.to take Augmentin 500 mg + 500 mg paracetamole 21all of these drugs can be used as prophylactic in asthma EXCEPT a.nedocromil sodium c.azatadine maleate 23abcde- indication for therapeutics of B-blockers includes essential hypertension thyrotoxicosis angina pectoris both a and b all of the above 24abcde- all of these drugs are controlled drugs EXCEPT epanutin rivotril stesolid diazepam none of them 25- clonidine www.com 48 .prometric-questions.astemazole b.to sponge him with tipped water and take him to the hospital e.None of the above 22all of these drugs are non sedating anti histaminic EXCEPT a.Salbutamol e. induces muscular relaxation through cholinergic receptor blockade d.both a and b e.lower blood pressure by combination of bradycardia and reduced cardiac output c.you will give him antiemetic c.loratadine e.prometric-questions.may cause rebound hypertension when suddenly withdrawn d.you will ask him to see the child www.terfenadine d.cetrizine c.is classified as α 2 adrenergic stimulant b.you will suggest him to go to hospital immediately b.com 49 .all of the above 27abcde- fundamental control effects of morphine include analgesia changes in mood mydriasis both a and b all of the above 28atropine routinely employed during general anesthesia in order to a.astemazole b.reduces salivary and respiratory tract secretion c.both a & b e.all of the above 26in patient who is asking for a decongestant (who is a truck driver) the best choice will be a.sedate the patient prior to induction of anesthesia b.a.all of the above 29a father came to see you and told you that a child (who is 5 Kg ) swallowed 10 tablet of aspirin for children and asking for an antidote a. you will give him antidote 30abcde- which one of these drug is not used for epilepsy clonazepam primidone phenytoin imipenem valproic acid 31abcde- which one of these drugs is not used for acute pain naproxen codeine colichicine prednisolone indomehacin 32digoxine serum concentration are monitored .since their elimination depend on a.com 51 .skin d.prometric-questions.all of the above 33abcde- which one of these drugs is NOT used for anxiety lorazepam alprazolam propranolol benzotropine none of the above 34abcd- which one of these drugs is NOT macrolide antibiotic Azithromycin Clindamycin Clarithromycin Erythromycin www.d.kidney c.both a and b e.liver b.you will suggest to him to ignore the incident e. None of the above www.Reducing the temperature to below 0°C may not extend the shelf life of creams because it causes cracking in creams c.Penicillin V c.com 51 . which of the following you suggest as the best alternative to his physician a.e.Reducing the temperature to below 0°C may not extend the shelf life of insulin because it causes aggregation of insulin d.Amoxicillin e.All of the above e.Gentamycin d.Telithromycin 35abcde- The most common route of drug entry to the cell is Uptake by special carriers Diffusion through the lipid phase Aqueous diffusion Transport by amino acid carrier Facilitated diffusion 36A patient who presents a prescription for erythromycin 500 mg Q6H for 10 days and your pharmacy didn’t have it.Clarithromycin b.prometric-questions.Generally a lower storage temperature decreases the rate of chemical and microbial degradation leading to increased shelf life b.Streptomycin 37abcde- Which of these drugs is NOT cough suppressant Dextromethorphane Pholocodine Morphine Guaiphenesin Codeine 38In storage of medicinal product a. Hyoscine e.The dose is small and a dose of a 180 mg is required d.Misoprostol b.Cinnarizine d.prometric-questions.The dose is too high as the daily dose is 5 mg / kg b.The dose is adequate but frequency should be Q6H only c.Methylcellulose c.The dose is adequate but frequency should be Q4H only 40Which of these drugs should be avoided during pregnancy a.Paracetamole 41abcde- which one of these drugs is NOT Beta agonist salbutamol fenterol pindolol pirbuterol albuterol 42abcde- protein binding of a drug can lead to Delayed urinary excretion of drugs Enhanced urinary excretion of drugs Decreased biological half life of drugs Both a and c None of the above 43abcde- Nitrous oxide is widely used in anesthesia because it Is non flammable and non explosive Provide rapid .The dose is in adequate and no need to call the doctor e.com 52 .39A child who came with prescription for paracetamol ( whose weight is 12 Kg ) and dose ( 5 ml Q4H to Q6H PRN ) you are going to tell the doctor to tell him a. smooth induction of anesthesia Is a potent muscle relaxant Both a and b All of the above www. How much does he need of each medication c.44abcde- Disulfiram ( tetra ethyl thiuram sulfide ) Effective treatment of alcohol withdrawal syndrome Prevent oxidation to acetaldehyde to acetate Protect the liver against damage by alcohol All of the above None of the above 45abcde- The duration of treatment of T.prometric-questions.All of the above e.Metabolism of drugs in gut wall and in the liver during the first liver passage d.Ciprofloxacin 47By definition first pass metabolism effect of drug is a.Which preparation of KCL want b.com 53 .None of the above 48A patient presents to you prescription for KCL and enalapril .Sucralfate b.None of the above www.Metabolism of drugs in the liver during the first liver passage c.If he suffer from hypertension e.Chlorophiniramine c.Is he using another antihypertensive d.Ethambutol d.Folic acid e. you are going to ask him a.Metabolism of drugs in gut wall during absorption b.B is 1 – 2 weeks 1 – 2 months 2 – 3 months 6 – 9 months 2 – 4 years 46Which of these drugs is contraindicated during pregnancy a. Use of prodrug can avoid high initial dose of parent drug since prodrug is changed to parent drug after administration d.The prodrug is less water soluble than parent drug and therefore will not precipitate in veins c.The prodrug is more water soluble than parent drug and therefore will not precipitate in veins b.49Hemisuccinate are used as prodrug for drugs to be given IV administration because a.com 54 .Antipyretic but not paracetamol 51abcde- All of these are side effect of chloramphenicol EXCEPT Irreversible a plastic anemia Optic neuritis Iron deficiency anemia Peripheral neuritis Gray baby syndrome 52abcde- Vasopressin is used in the treatment of Diabetes insipidus Type I Diabetes mellitus Type II Diabetes mellitus Peripheral neuritis Angina pectoris 53According to ministry of health (MOH) regulation narcotic prescription can be dispensed by the pharmacist when www.prometric-questions.Both a and b e.Both a and c 50abcd- What is the active ingredient of dolomol Paracetamol which is an anti inflammatory drug An analgesic but not paracetamol Paracetamol which is an analgesic and anti inflammatory drug Paracetamol which has no an anti inflammatory but has an analgesic activity e. identification number written clearly on the prescription c.None of the above e.Sustained release tablets should be crushed before dissolving when given to a patient with dysphagia www.3.1.PDR c.45 % d.6 % 56abcde- What is the major complication of morphine over dose AV block Respiratory depression Cardiac arrest Liver dysfunction Kidney dysfunction 57Which one of the following statement is INCORRECT a.0.a.225 % e.com 55 .Having the prescriber name .All of the above 55The concentration of NaCL in dextrose 5% normal saline (D5W/NS) is a.Having a clear patient name and identification number written clearly on the prescription b.0.The prescription can be filled maximum of 3 days after it has been written d.All of the above 54In which of the following references you can find the answer if you asked by a patient to identify an orange tablet with a printed code of F12 a.9 % c.SNF d.0.Martindale b.A syrup is an aqueous solution that has sweet taste b.Both a and c e.8 % b.prometric-questions. c.More than 7 c.Normal saline e.Alcohol d.Dextrose with 5 % sodium bicarbonate c.Regular tablet is a solid dosage form e.Less than 7 www.Ringer solution with dextrose 62The PH of acidic preparation a.Elixir is a solution that contain alcohol as a diluents d.7 b.Glycerine with 5 % sodium bicarbonate b.com 56 .prometric-questions.Emulsion is a mixture of oil and water by the use of surfactant 58abcde- Intra osseous injection refers to injection into the Bone marrow Superficial skin layer Muscle mass Pleural fluid Spinal cord 59abcde- The trade name of cotrimoxazole is Bactrim® Ultracif ® Comazole ® Augmentin® Salinal ® 60abcde- The recommended dose of paracetamol for 10 Kg child is 50 mg every 6 hours 150 – 300 mg four times daily 15 mls every 4 – 6 hour 100 – 150 mg every 4-6 hours 10 mg / 4 hour 61Which one of the following preparation can be used externally as otic waxes remover a. 1% hydrocortisone is mixed with 2.5.9% normal saline a.450 milligrams d.5 grams 67If 30 gram of 0.Amphotricin B d.Insulin e.0.15 b.4.5% of hydrocortisone what is the percentage of hydrocortisone in the final mixture www.45 grams b.Cefazolin c.4500 milligram e.d.prometric-questions.4.75 66How much sodium chloride is required to prepare 500 ml of 0.30 c.60 e.45 d.Phenytoin b.5 – 8.Zantac 65How many gram of magnesium oxide are required to make 300 ml of 15% (W/V) solution a.6 – 8 63abcde- Eight fluid ounce 240 ml 120 ml 60 ml 30 ml 15 ml 64Which of the following drugs should not be mixed with normal saline for intravenous administration a.com 57 .5 milligrams c.5 e. 75 % W/W 1.abcde- 2.All of the above 70abcde- All of these drugs are antifungal agents EXCEPT Nystatin Itraconazole Flucytosine Mirtazapine White field ointment 71abcde- QID mean Every day Every other day Four time a day Every four day Every 12 hour www.25 % W/W 1.Both b and c e.com 58 .2 % W/W 1.Drug must be taken with a full glass of water at least 30 minutes before any food c.prometric-questions.35 % W/W 68abcd- Quinolone is not recommended in children because They are not very effective unlike the adult They have serious side effect on the liver They affect the joint causing cartilage erosion They make the child hyperactive .Patient must not lie down for at least 30 minute after taking alendronate d.Drug must be taken first thing in the morning b.Cause discoloration of teeth 69The advice you will give to the patient when dispensing alendronate (fosamax®) to treat osteoporosis a. irritable and may cause seizure e.85 % W/W 0. com 59 .Labetalol 73New guideline for asthma treatment is a.Clarithromycin b.Cerivastatin b.Omeprazole c.Show benefits in reducing the risk of cancer b.All of the above e.Show no benefit compared with placebo and it may increase risk of breast cancer e.Sumatriptan c.prometric-questions.Can be used for life as it showed protective effect without any side effect d.It increase the risk of osteoporosis 76Pharmacodynamic is defined by a.Fusidic acid injection e.None of the above 74Which drug is consider cytochrome P-450 enzyme inhibitor a.Pamidronate d.To give inhaled steroids for short time because it may affect the growth b.The study of biochemical and physiological effects of the drug www.To use long acting B2 agonist along with inhaled steroids for long time d.72Which one of the following medication have been ……………………………due to incidence of rhabdomylosis a.To use short acting B2 agonist on regular basis c.Ciprofloxacin 75Hormone replacement therapy (HRT) for women recently a.It significantly reduces the risk of heart disease c.Rifampicin e.Phenytoin d. Vasoconstriction of pulmonary alveoli d.Felodipine b.Take the child to the emergency department d.b.Vasoconstriction and increase systemic blood pressure and coronary blood flow c.Lamivudine e.prometric-questions.Watch the child for the next 48 hr c.com 61 .Study of effect and adverse effect of the drug e.All of the above 77A father seeks for advice for his 2 month old child complaining of runny nose and temperature 39°C. and side effect of the drug c.Nifidepine d.Verapamil 80Norepinephrine stimulate B1 adrenergic receptor and alpha adrenergic receptor causing a. dosage form .Give him paracetamol and Actifed b.Both a and b www. what is the best advice to him a.Drug interaction .Start him immediately on amoxil e.The study of time course of a drug and its metabolite in the body after administration d.Combine paracetamol and amoxil 78abcde- The drug of choice of head lice is Topical steroids Pyrithrins Anti histamines Antibiotic Anti fungal 79All of these drugs are considered calcium channel blocker EXCEPT a.Increase contractility and heart rate b.Deltiazem c. com 61 .Stop the medication 84abcde- Indications for therapeutic use of B.Xanax® 82The well known complexion of reaction warfarin and certain drugs containing metal ions such as aluminium hydroxide leads to a. the best advice way to discuss with him the following a.Formation of complexes in the GIT tract that cause irritation d.The most important drug for his regimen e.Formation of complexes in the GIT tract that are highly absorbed c.Pravastatin ® d.Bisacodyl® b.Long term complication of CHF and DM if not properly treated c.None of the above 83A 55 year old patient with a history of congestive heart failure (CHF) and diabetes mellitus (DM) who is not compliant with his 5 medication .Formation of complexes in the GIT tract that are poorly absorbed b.Metformin ® e.All of the above e.blockers includes Essential hypertension angina pectoris glaucoma both a and b all of the above www.e.All of the above 81These drugs cannot dispensed to patient without prescription EXCEPT a.Side effect of his medications in details b.Tegretol ® c.prometric-questions.Drug interaction of digoxin d. com 62 .Hanging your certificates and awards on the wall or your desk b.prometric-questions.85abcde- All these drugs are controlled drugs EXCEPT Carbmazepine® Rivotril ® Tylenol ® Diazepam ® Fosamax ® 86The drug of choice for the treatment pseudomembraneous colitis a. there for its co administration with a drug that is metabolized by liver would lead to a.Talking to patient according his/her level of education c.Increased rate of metabolism of that drug leading to decreased response to drug www.Vancomycin 87abcde- The insulin that cannot be given IV NPH Regular Insulin lispro All of the above None of the above 88During patient counseling on medication what are the things that make patient feel confident and comfortable about information you give a.Metronidazole b.Ciprofloxacin d.Both a and b e.Aspirin e.All of above 89Isoniazide is known to be a liver enzyme inhibitor .Clindamycin c.To assure patients compliance with his/ her drugs don’t discuss major side effects with patients d. Co trimoxazole d.Enzyme induction b.Enzyme inhibition d.Increased rate of metabolism of that drug leading to increased response to drug c.Decreased rate of metabolism of that drug leading to increased response to drug e.All of the above 92The most common side effect for oral hypoglycemic drugs is a.GIT upset c.Penicillin c.Decreased rate of metabolism of that drug leading to decreased response to drug d.b.All of the above 90abcde- Nitroglycerin skin patches ( nitroderm -5) means It contains 5 mg only It contains 5 mg / hour It delivers 5 mg / 24 hour It deliver 5mg per 12 hour All of the above 91Drug -drug interaction may take place by the following mechanism(s) a.Thyroid gland suppression b.all of the above 93Which one of the following drugs is contraindicated in a patient with G6PD deficiency a.prometric-questions.com 63 .Acetaminophen b.Dexamethasone www.Plasma protein displacement e.Formation of unabsorbed complex c.Allergic reaction d.Hypoglycemia e. he asked you what he should do? Your advice is a.Rifampicin 97abcde- Viagra® has fatal drug interaction with Carbamzepin Nitrogycerine Ketamine Zithromax atenolol 98The following drugs may cause discoloration of the feces EXCEPT www. which one of these drug may increase warfarin effect a.This is a common side effect of valproate and do not do any thing d.Amiodaron d.Carbamazepine b.Give hydrocortisone cream 1% to be applied on the affected area e.Seek medical advice immediately because it might get worse b.Reduce the dose immediately 95abcde- What is the salt form of fer-in-sol Ferrous fumarate Ferrous gluconate Ferrous sulfate Ferrous succenate Ferric sulfate 96Patient is taking warfarin .Oral contraceptive e.Vitamin K c.Start another antiepileptic drug and stop these two c.prometric-questions.com 64 .e.Insulin 94Epileptic patient complaining of mild skin rash and he is taking lamotrigine and sodium valproate . abcde- Phenytoin Iron salt Rifampicin Warfarin None of the above 99The maximum recommended dose of diclofenac (voltaren®) for adult is a.prometric-questions.50 mg b.100 mg d.150 mg e.None of the above 100abcde- Cephalexine is First generation cephalosporin which coves G+ organism One of the quinolone Second generation cephalosporin which coves G+ organism One of the amino penicillin Third generation cephalosporin which coves G+ organism www.75 mg c.com 65 . Urokinase d.All these drugs cause anti metabolic effect except a.Streptokinase c.Anticoagulant b.All these drug are fibrinolytic except a.Antibiotic c.Irreversible a plastic anemia b.Alteplase e.Iron deficiency anemia e.Optic neuritis c.Methotrexate b.prometric-questions.Anti depressant 4.Angina pectoris c.Hypertension b.Cyclophosphamide www.Dipyridamole b.Prophylaxis of migraine d.Anti cholinergic e.Flurouracil c.Azothioprime e.Anti emetic e.Ticlopidine is used for a.Cytarbin d.All of these is side effect of chloramphenicol except a.com 66 .Megaloplastic anemia 3.Anti epileptic 2.Exam model 4 1.Peripheral neuritis d.Non of the above 5.Ondasetron Hcl is used for a.Anti platelet d. All these drugs can be used for parkinsonism except a.pergolide 7.Ephedrine b.Nedocromil sodium e .Normal saline e.selegiline b.Propranolol d.Hyperglycemia h.prometric-questions.6.Hydrocortisone 9.Protamine sulphate b.Vitamin K d.Cardiac arrest could be management by the following except : a.Antidote of heparin is a.Hypernatremia g.All these cases not cure with thiazide except : f.Hypokalemia i.com 67 .Ledocaine c.None of the above 10abcde- Antidote of warfarin is Protamine sulphate Acetyl cystiene Vitamin K Naloxone None of the above 11Antidote of paracetamol is a.Hyponatremia 8.Protamine sulphate www.levodopa d.Acetyl cystiene c.Hyperuricemia j.Naloxone e.carbidopa c. No change of drug solubility www.bcde- Acetyl cystine Vitamin K Naloxone None of the above 12abcde- Antidote of morphine is Protamine sulphate Acetyl cystiene Vitamin K Naloxone None of the above 13abcde- Disease cause edema Renal failure Congestive heart failure Hepatic disease Both a and b All of the above 14abcde- Simvastatin Anti hypertensive agent Hypolipdemic agent Anti hyperlipidemic Both b and c All of the above 15abcde- Side effect of corticosteroid include Water and sodium retention + hypertension Gastric ulcer + glaucoma Osteoporosis + DM + Cushing syndrome Both b and c All of the above 16Biotransformation is conversion of the drug to a.prometric-questions.com 68 .More lipid soluble b.Less lipid soluble c. Any of them e.prometric-questions.com 69 .None of them 17abcde- Phenyl ephrine is used Decongestant For runny nose Sympathomimetic All of the above None of the above 18abcde- Oxytocin produces all of the following except Progesterone release Uterine stimulation Labor induction Mammalian gland stimulation Both a and b 19abcde- New & best therapy for peptic ulcer is Antacid + H2 antagonist Use more than one H2 antagonist triple therapy including antibiotic double therapy including proton pump inhibitor none of the above 20abcde- In case of arthritis & peptic ulcer Of elderly patient use Aspirin Paracetamol Diclofenac Indomethacin Piroxicam 21abcde- Give names of drugs the drug changes the color of urine Nitrofurantoin Phenazopyridine Rifampicin Both a and c All of the above www.d. com 71 .prometric-questions.Bronchial asthma www.22abcde- Drug of choice of febrile convulsion in children Valporic acid Phenytoin Gabapentin Carbamazepine Non of the above 23abcde- Cyproteron (androcure )is used for Increase sexual abilities in male Treat hairsiutism in female Treat prostate cancer Treatment acne All of the above 24abcde- Immunocompetent means Control resistant to infection Low resistant to infection Increase immunity in patient Gama Immunoglobin None of the above 25abcde- Immunocompromised means Control resistant to infection Low resistant to infection Increase immunity in patient Gama Immunoglobin None of the above 26abcde- Difference between captopril & other ACE inhibitor Mode of action Site of action Potency Both a and b All of the above 27Gluco corticoid used in a. com 71 .Iodine d.Propyl thiouracil e.1:5 b.2:3 c. anti stress All of the above 28Cotrimoxazole contain Trimethoprime and Sulphamethoxazole as a.Vomiting d.Lugols solution 31abcde32- One of the following is the drug of choice for amoeba Chloramphenicol Tetracycline Gentamycin Metronidazole Mebendazole One of the following is given once daily www.Diarrhea c.1:6 29One of the following symptoms is not side effect of morphine a.Thyroxin sodium c.bcde- Addisons disease Suppression therapy Anti shock .None of the above 30One of the following is the drug of choice for myoxedema ( hypothyroidism ) a.Carbimazole (Neo – mercazole ) b.Respiratory depression e.prometric-questions.1:3 e.Constipation b.1:4 d. abcde- Amorphous insulin Natural insulin Protamine Zinc insulin Regular insulin All of the above 33abcde- Ferrogard is Ferrous gluconate Ferrous sulphate Ferrous citrate Ferrous fumarate Ferric sulphate 34abcde- What does QOD stands for Four times daily Every 4 hours Every other day Once daily Four time every other day 35abcde- One of the following is not calcium channel blockers Verapamil ( Isopten ) Amlodipine (Amlor ) Diltiazem (Dilizem) Cinnarizine (Stugeron ) Nifidepine (Adalat) 36abcde- The dose of paracetamol for a 3 month old baby 5 – 10 mg / kg / 4 hour daily 5 – 10 ml / 6 hour daily 120 – 250 mg / kg / 4-6 hour daily 250 – 500 mg / kg / 4 hour daily 10 – 15 mg / kg / 4-6 hour daily 37Which of the following is not NSAIDs a.prometric-questions.Parafon www.com 72 .Ibuprofen b. The drug affect the fetus to small extent www.Aspirin 38abcde- Antidote of digoxine Digitoxine Charcoal Digibinide Naloxone Tranxamic acid 39If prescription contains atenolol and the patient is wheezing a.Call the doctor and ask him about the case c.Give him the medicine b.prometric-questions.Don’t dispense the drug 40abcde- B agonists cause Increase oxygen consumption ectotropic effect Inotropic effect Both a and c All of the above 41abcde- The best guide to patient is Tell him about all side effect of the drug Tell him about mechanism of action of the drug Tell him about some side effect of the drug Tell him about all advantages of using the drug None of the above 42Simvastatin is categorized by FDA as pregnancy category X this mean that a.c.Ask him if he is taking other anti hypertensive d.The drug is contraindicated during pregnancy b.Naproxen d.com 73 .Tenoxicam e.Ask him if he is asthmatic e. ….The drug should be used with caution during pregnancy d.prometric-questions.age.The drug is absolutely safe to use 43abcde- Regular insulin can be used by IV IM SC Both b and c All of the above 44abcde- In control prescription ( Narcotic prescription) should be Identification of patient (name .com 74 .The drug is used in third trimester e.etc) Identification of patient and signature of doctor and patient Not dispensed after 3 days of prescribing Both a and c All of the above 45abcde- Cisaprid was pulled from market by MOH side effect Anemia Nephrotoxicity Arrhythmia Leukemia Heart failure 46abcde- Which of the following is natural emulsifying agent Acacia Lactulose Paraffin oil Span Tween 47abcd- All of the following are thiazide diuretic except Chlorothiazide Hydrochlorothiazide Amiloride Indepamide www. address .c. ASA (acetyl salicylic acid ) so the mixture will be : a.prometric-questions.Heart lane d.All of the above 49abcde- Microdex is New drug for hypertension New drug for hypertension Software program for disease and drugs New drug for hypertension Reference of pharmacological drugs 50If you have prescription containing water 60 gm .Suspension c.Chlorothalidone 48If doctor ask you about the recommended dose of Cefuroxime what is the reference you will use a.0065 gm None of the above 52abcd- Cytotic was pulled from the market due to side effect of Abortion Anemia GIT irritation Diarrhea www.065 gm 0.SNF b.e.5 gm 0.com 75 .Solution e.Emulsion 51abcde- Grains 65 gm 6.BNF e.Syrup d.Elixir b. olive oil 120 gm .AHFS c. com 76 .Amiloride c.Ethacrynic acid 54abcde- What is the active ingredient in Viagra® Sildenafil Silfenadil Sildefanil Sldenadil None of the above 55abcde- Antihistaminines are not given to babies because Sleeping side effect Liver toxicity Nephrotoxicity Peptic ulcer None of the above 56What is the concentration of NaCl in Dextrose 5% & ½ N.Chlorothalidone e.0.Furosmide b.9 NaCl 57abcd- The PH of eye preparation is 2.225 NaCl e.Bumetanide d.3 4-6 >6 6-8 www.0.9 NaCl b.25NaCl c.e.prometric-questions.45 NaCl d.Migraine 53Which of the following diuretic may cause Hyperkalemia a.S a.0.0. Reduce the dose of the drug 60Female patient tell you that she takes phenytoin and noted hairsiutism (excessive hair growth) what will you till her? a.Stop medication immediately b.Reduce the dose of the drug 61Nurse ask you to dilute 3 ml lidocain 1% to 1: 1000 ho many ml of water you will need a.0.9 % d.1.com 77 .5% the concentration of the mix will be a.2 % 59Patient tells you that he takes phenytoin and noted hairsiutism (excessive hair growth) what will you till him? a.30 ml d.8-10 58If you mix 60 gm of hydrocortisone cream 1% with hydrocortisone cream 2.2.300 ml e.1.Stop medication immediately b.Stop phenytoin and give her alternative e.Its common side effect of phenytoin and do nothing d.85 % e.e.Stop phenytoin and give her alternative e.25 % c.Ask doctor for alternative c.3 ml www.prometric-questions.100 ml b.1.Its common side effect of phenytoin and do nothing d.75 % b.10 ml c.Ask doctor for alternative c. prometric-questions.advice him to go to hospital d.62Bycol ® was pulled from the market due to fatal side effect of a.Advice the father to sponge with water c.152 ml c.give him antibiotic and anti pyretic e.135 ml d.both b and c 66Solution of 160 ml containing 5% NaCl how much water in this solution a.Give him Tempra + Actifed b.100 ml b.Leukemia c.Abortion 63abcde- Intrathecal is Spinal cord Intra joint Tracheal Subcutaneous Intra dermal 64abcde- Enteric coated tablet disintegrate by PH of the stomach PH of the intestine PH of the oesphageus Both a and c All of the above 65Patient coming with a 2 months baby with 39°C what will you do a.CNs manifestation d.8 ml e.Osteoarthritis b.130 ml www.com 78 .Rhabdomiolysis e. Fludrocortisones d.com 79 .None of the above 71All of these may reduce the anti coagulant effect of warfarin EXCEPT a.None of the above www.Amphotricin B e.Predinsolone c.Aminoglycoside c.prometric-questions.67One of the following corticosteroid is mineralocoricoid group a.Aspirin e.Oral contraceptive d.Hydrocortisone b.Dexamethasone 68abcde- Ephedrine should not used in patient had Cough Nasal congestion Bronchospasm Heart disease Both a and b 69abcde- Which one of the loop diuretic is more potent than other Fuoresmide Torasemide Bumetanide Ethacrynic acid None of the above 70Which of the following has minimal or no adverse effect on kidney a.Betametasone e.Cephalosporin d.Chloramphenicol b.Rifampicin c.Vitamin K b. Captopril e.72abcde- One of these is NOT used for ascaris infection therapy Niclosamide Piperazine Mebendazole Pyrantel Levamisole 73With drug that classified as non linear kinetic .Hyoscine e.Increase in the amount of the drug absorbed c.Diuretics 75One of these drugs is NOT suitable for treatment of gastrointestinal colic a.Proportional increase in the plasma concentration 74In patient with ischemic heart disease which of the following drug is contraindicated a.Nadalol c.Isorbide dinitrate d. any increase of dose result in a.Disproportional Increase in the plasma concentration e.Atropine 76abcde- Food poisoning is caused by Virus Bacteria Worms Tinea Parasite www.Xylometazoline c.Papverine b.com 81 .Increase in the amount of the drug eliminated b.Increase in the half life d.prometric-questions.Ephedrine b.Alverine d. Thyroid extract www.The dose limit applies to only one of them d.None of the above 81Hypercalcemia is a sign of toxicity of a.Use 2 proton pump inhibitor simultaneously 80Tuberculosis is a disease which should be treated with a.Both a or b e.The difference in their site of action 79The new therapy for peptic ulcer has been changed recently into a.77abcde- On of these is not useful for aspergillosis Itraconazole Fluconazole Amphitrocin Both a and b None of the above 78There are major clinical differences between the different members of ACE inh. a.Single drug to avoid resistance b.Using more than H2 antagonist simultaneously d.Using a combination of three drugs one of which should be an antibiotic e.There are differences and some of them are proven to be more effective than others c.Three or four drug initially to assure eradication of micro organism d.Two drug in order to shorten therapy period c.The difference in their mode of action e.Use higher than the doses that were used previous c.No they are basically equally effective if used in appropriate doses b.com 81 .prometric-questions.Add antacid to be used on PRN basis b.Parathyroid extract b. Both a and b e. you must consider person GFR which is reflected by a.Serum Creatinine b.prometric-questions.All of the above 82abcde- Gluco corticoid can be used in treatment of Addison's disease Hypopitutarism Severe bronchial asthma All of the above None of the above 83Regarding Amiloride /triametrine /spironolactone which is correct a.Vitamin D d.c.None of the above 85abcde- The new non sedating anti histaminic are H2 antagonist H1 antagonist D2 antagonist Both a and b All of the above 86Which one is consider enzyme inducer a.Treat Hyperlipidemia 84When dosing with aminoglycoside .Amount of urine d.Both a and c e.May lead to Hyperkalemia e.Rifampicin b.May lead to hypokalemia c.Chloramphenicol www.com 82 .Not used for oedema d.Not belong to the same therapeutic class b.Creatinine clearance c. Decrease effect of lipid soluble drug www.Ask the patient to avoid taking drug with food b.Cimitidine d.prometric-questions.Vitamin C 87When dispensing drug that cause allergic reaction such a penicillin and sulfonamide the pharmacist should a.Increase cardiac output b.Increase hepatic blood pressure c.Omeprazole e.Ask patient if he is allergic to the drug d.Ask patient to avoid taking drug with milk c.c.Both a and c e.com 83 .All of the above 88abcde- Metoclopramide is Dopamine antagonist with indirect cholinergic activity Has strong central anti emetic property Trade name is plasil Both a and b All of the above 89abcde- Flumazenil Benzodiazepine Barbiturate Benzodiazepine antagonist Barbiturate antagonist None of the above 90abcde- Mivacurin Non depolarizing muscle relaxant Depolarizing muscle relaxant Antibiotic Analgesic antipyretic Non of the above 91Geriatric one of the these are NOT occur EXCEPT a. Decrease gastric secretion e.Acetyl cystine c.prometric-questions.Naloxone e.Decrease memory efficiency 92abcde- Astemazole Long acting antihistaminic Short acting histaminic Similar to chlorphenramine maleate Both b and c Non of the above 93abcde- Triazole Is antifungal Is trade name of amphterocin B Is trade name of clotrimazole Is trade name of nystatin Is antibiotic 94abcde- Which of these has NO vasodilating effect Methyldopa Enalapril Hydralazine Prazoscin Propranolol 95abcde- One of these may used as topical eye ointment Amikacin Netilmycin Streptomycin Tobramycin Kanamycin 96-Antidote of warfarin a.Protamine sulfate b.Desferroxamine www.d.com 84 .Vitamin K d. 1 dihydroxy cholecalciferol c.prometric-questions.Both a and b e.1.com 85 .Cyanocoblamine c.Has alpha adrenergic blocking activity c.Enalapril b.Ascorbic acid d.25 .None of them 100-Which one of these drugs is NOT angiotensin converting enzyme inhibitor (ACEI) a.Tocopherol e.Captopril www.25 dihydroxy cholecalciferol b.25 dihydroxy cholecalciferol d.Riboflavin b.Has non selective beta adreno receptor blocking activity b.97-Give the name of vitamin B12 a.Menadione 98-Carvedilol a.Quinapril d.Has alpha agonist activity d.Lisinopril c.1.Both a and c 99-Calcitriol a.Both a and b e.Zarapril e. Allopurinol effect through a.10 b.Recommended serum phenytoin level in epileptic patient a.prometric-questions.Irritant ( stimulant ) laxative d.33 3.20 – 30 ug/ml d.Bulk forming laxative b.Less hepatotoxic b.Inhibit xanthine reductase enzyme b.20 d.30 – 35 ug/ml e.Less than 10 ug/ml b.more absopative d.com 86 .Osmotic laxative c.10 – 20 ug/ml c.Both a and d www.Inhibit xanthine oxidase enzyme c.Depakot main advantages over depakin a.Exam model 5 1.More than 35 ug/ml 4.Decease uric acid synthesis e.30 e.non of the above 5.Lubricant laxative e.Increase uric acid execretion d.Less nephrotoxic c.12 c.Percent of elemental iron in ferrous gluconate is a.Less GIT irritation e.None of the above 2.Type of psyllium laxative a. Parenteral preparation b.Both a and b e.Atenolol e.prometric-questions.6.Sustained release drug delivery depend on a.Both a and b e.Digoxine c.Gentamycin b.Medium PH c.Iron d.Zarapril e.com 87 .All of the above 8.Vitamin B12 b.Enalapril c.Lisinopril b.Vancomycin www.Captopril d.Enzymatic activity d.In renal impairement dosage interval should be adjusted for all except a.Pyridoxine c.Which one of them is not ACE inhibitor a.Lidocaine d.Sterilization is necessary for a.None of the above 7.All of the above 10.Oral preparation d.Sodium e.Ophthalmic c.Interaction with body fluid b.Calcium 9.The heme portion of haemoglobin contain a. Single dose package container packed in the pharmacy must have expiration date a.11.Intramuscular injection e.SR tablet should be crushed e.10 % of remain self life of the stock but not longer than 12 month 12.25 % of remain self life of the stock but not longer than 6 month c.Medium PH c. supplement a.Require vitamin B12 d.Solution c.Require vitamin B6 b.Controlled drug delivery (already programmed) depend on a.Both a and b e.Enzymatic activity d.Isoniazide is primary anti TB infection require ……….Which should be not prepared in horizontal laminar flow a.All of the above 16.Solution is the most rapid oral dosage form c.Require vitamin B2 c.35 % of remain self life of the stock but not longer than 4 month d.Enteric coated tablet pass the gastric PH b.20 % of remain self life of the stock but not longer than 6 month e.com 88 .Intravenous injection b.Require vitamin B5 15.IV give 100 % bioavailability d.Thyroid hormone www.prometric-questions.Most common route for insulin injection is subcutaneous 14.10 % of remain self life of the stock but not longer than 6 month b..Interaction with body fluid b.Intradermal injection 13.Large volume fluid d.Which one of the following is incorrect a.Require vitamin B1 e. com 89 .No effect on absorption e.Not absorbed from GIT d.All of the above 17.Easily absorbed from GIT c.Both A& D 18.Increase t½ b.a.Tetracycline b.Poorly absorbed from GIT b.Hyperlipedmia e.Not stable in gastric PH e.Hypertension c.decrease t½ c.Poorly absorbed from GIT b.Warfarin when taken with aluminum hydroxide a.release from parathyroid gland d.prometric-questions.Binding to plasma protein a.Ulcerative colitis d.Pseudomemberaneous colitis is treated by a.no affect t½ d.Easily absorbed from GIT c.None of the above 19.Mesalasine a.Dobutamine is given IV because a.Not absorbed from GIT d.All of the above 20.None of the above 21.Vancomycin www.same to all drugs e.Growth hormone c.GERD disease b.Both a and b e.Control temperature b. com 91 .All of the above 26.Span c.both A& C www.Saudi national formulary c.None of the above 24.None of the above 23.Aspirin is recommended with a.Smooth muscle relaxant d.Both a and b e.Miosis c.All of the above 25.Tween b.Slovenia national formulary e.Analgesic b.Addiction d.Tecloplanin d.Both a and b e.Chicken box c.Anticoagulant b.Spain national formulary b.Saudi national formulation d.What is mean of SNF a.c.Sodium lauryl sulphate d.Both b and c 22.Both a and b e.Antimuscarinic c.Ibratropium bromide is used as a.Dysmenorrheal d.All of the above e.prometric-questions.Bronchodilator b.Morphine differ from mepropamate in a.Surfactant not used orally a. Mixed G+VE and G-VE d.Diclophenac b.G-VE c.rate of binding d.Flagyl c.therapeutic volume e.none of the above 31.all of the above e.com 91 .G+VE b.One drug is not used for acute diarrhea a.Dexamethasone e.plasma concentration of the drug in all body mean a.Metronidazole b.UTI infection caused by a.cetrizine c.None of the above 30.rate of distribution c.rate of absorption b.Aspirin c.non of the above www.prometric-questions.Paracetamol 28.None of the above 27.Both a and b e.Indomethacin d.Both a and b e.chloropheneramine maleate d.loratidine b.Tetracycline d.All of these drug have anti inflammatory except a.e.the only sedative anti histaminic a.None of the above 29. Trust b.Liver b.none of the above 35.All of the above 37.Bowel mucosa d.blood e.Both a and b e.Un ionized hydrophilic b.saliva 33.The metabolism in the body occur in a.taking money from patient d.prometric-questions.32.com 92 .Induce labour b.exchange benefits c.urine c.skin b.all of the above 36.Drug pass BBB should be a.both A& B e.Mamilian gland stimulation d.The relationship between the pharmacist and the patient is based on a.Uterine stimulation c.Oxytocin make the following EXCEPT a.ionized hydrophilic c.Progesterone release e.the source of HCG ( human chronic gonadotropine ) is the urine of pregnant women a.ionized lipophilic e.Protein bound of drug forming compound which is www.Kidney c.None of the above 34.Un ionized lipophilic d.stool d. The concentration of crystal violet paints a.Skin disinfectant c.Tilade® inhaler generic name a.Sodium stibogluconate e.Nedocromil sodium d.Inactive while the free part is active b.antifungal e.Abbreviation of INH mean a.Terbutaline c.0.Emollient d.Isonicotinic acid hydralazide c.Sun screen 41.Both a and c 42.Digoxine d.Drugs that has narrow region between therapeutic and toxic dose a.Theophylline c.Isoniazide b.1 % in USP 1985 d.Sodium thiocyanate 39.a.uses of gentian violet (crystal violet) a.Antiseptic b.All of the above 40.prometric-questions.0.Isonicotinic base hydrazide www.None of the above 38.active while the free part is inactive d.Inactive and the free part is inactive c.5 % in BP 1985 e.5 % in BP 1980 b.Warfarin b.com 93 .1 % in BP 1980 c.Both a and b e.active and the free part is active e.Salbutamol b. The antidote of copper and lead a.Desferroxamine b.Dextrose e.None of the above 43.The antidote of heavy metal as antimony.Dextrose e.gold .Both and b e.Desferroxamine b.Dextrose e.Desferroxamine b.1 % b.2 % c.com 94 .Sodium thiosulphate 45.Penicillamine c.5 % 44.Dimercaprol d.Sodium thiosulphate 47.mercury and bismuth a.Sodium thiosulphate 46.Dimercaprol d. arsenic .4 % e.prometric-questions.Dimercaprol d.Penicillamine c.The concentration of mercurochrome solution is a.3 % d.Dimercaprol d.d.The antidote of iron a.Desferroxamine b.Penicillamine c.Penicillamine c.Dextrose www.The antidote of insulin & oral hypoglycemic a. Diabetes mellitus d.Hypertension d.An ovulation infertility b.amikacin b.One of these may be used as topical ointment a.the following drugs used in acute diarrhea except a-metronidazole b.streptomycin d.All of the above 51.gentamycin c.Both a and b e.Sodium thiosulphate 48.Oral anti diabetic d.loperamide c.tetracycline e.Clomphene citrate used for a.All of the above 50.tobramycin e.prometric-questions.Hypercholestremia c.Hyperthyroidism e.Oral contraceptive c.Hyperlipidemia b.both B& D 52.Clonidine is used as a.Cholystramine is used for a.non of the above www.com 95 .gentamycin d.Anti hypertensive acting centrally b.Prevent the recurrence of migraine c.Non of the above 49.Both a and b e.e. precursor of dopa b.lipobay ® removed from market as it cause a.stimulate dopamine e.by oral & injection c.heart problems b.brain problems c.azoles b.these agents used for systemic fungal infections except a.grisofulvin e.effective in parkinsonism d.all of these are true for levodopa except a.B barrier c.flucytosin d.these agents used for superfacial fungal infections except a.aminoglycosides antibiotic is taken a-by injection because it's slowly absorbed from intestine b.by injection due to degradation by gastric juice d.amphotricin –B c.com 96 .non of the above 56.azoles b.abortion d.don't pass the B.both A & B e-all of the above 54.combined with carbidopa 55.53.used to treat acne www.amphotricin –B c.prometric-questions.flucytosin d-grisofulvin e-non of the above 57.death e.non of the above 58- roacutane ® a. 22 gauge c.grisofulvin b.death e-non of the above 60.3000 mg / day d.24 gauge www.bcde- contraindicated in pregnancy cause arrythemia both A& B All of the above 59.25 gauge b.one of these antifungal taken via Parenteral route only a.com 97 .all of above 63.maximum dose of ibuprofen is a.1800 mg / day b.120 mg / day e.miconazole d.maximum dose of nifedipine is a.the largest diameter of needle is a.probelced ® removed from market as it cause a-heart problems b.abortion d.prometric-questions.1500 mg / day e.B c.60 mg / day c.30 mg / day b.3200 mg / day c.90 mg / day d.180 mg / day 62.brain problems c.non of the above 61.gentian violet e.amphotercin. arrythemia d.increase number of alpha receptors c.pain in intestine e.occurs with chronic bronchitis e.corticosteroids in treatment of asthma a.which is correct a.associated with sputum d.qod : every 3 hours c.atrial fibrillation e.q3h : four times daily d.30 gauge 64.non of the above 66.os : in left eye e.bradycardia b.od : in both eyes 65.tackycardia c.decrease inflammation combined with asthma b.non of the above 68.all of the above 67.diarrhea c.one of these is not occurs with irritable bowel syndrome a.20 gauge e.the heart beat is 50 so it's called a.is chronic obstructive pulmonary disease b.qid : every other day b.constipation b.decrease sputum combined with asthma d.non of the above www.all of the above e.anatomical change of lung c.d.com 98 .vertigo d.prometric-questions.emphysema a. coli can cause a.sulfonyl urea only c.sulphonyl urea act as www.rifampin 600.non of the above 72.900 mg /d po for 6 weeks c.All of the above 70.A& B OR A & C e.all of the above e.insulin only b.6 weeks c.Parenteral preparation c.6-9 month e.gastrointestinal infection c.urinary tract infection b.B& C 71.non of the above 73.9 weeks d.need aseptic technique a.type 1 diabetes mellitus use a.69.doxycycline 100 mg po bid for 6 weeks b.meningitis d.com 99 .prometric-questions.treatment of brucellosis is a.extemporaneous preparation d.Non of the above 74.Time for treatment of brucellosis is a.both A & B e.3 weeks b.streptomycin 1g / d IM daily for 2-3 weeks d.biguanide d.E.both A& B e.ophthalmic preparation b. disintegration test d.chloropropamide b.acetazolamide e.acetohexamide c.stimulate glycolysis in tissues e.dissolution test c.diamox® it's generic name is a.both A& B e.com 111 .stimulate secretion of endogenous insulin b.non of the above 76.non of the above 79.inhibit degradation of free active insulin d.non of the above 75.Filtration test e-non of the above 77.All of the above 78.increase in chemical stability b.stability test b.a.test used to ensure free from microorganisms a-sterility test b-clarify test C-disintegration test d.pyrogen test e.psoriasis www.decrease in size of solid dosage form lead to a.test used to ensure free from microorganisms a.prometric-questions.slowing of glucose absorption c.gliplizide d.chicken pox c.one of these is not a chronic skin disease a.decrease in therapeutic effect d.eczema b.increase is surface area c. benzyl peroxide used to treat a.all of the above 80.gentamycin www.which is not aminoglycoside a.opoids c.prometric-questions.tinea 84.netilimycin b.large volume fluid d.bacteria e.non of the above 81.not taken with horizontal laminar flow a.fungi b.parasite d.kanamycin d.antibiotics b.antibiotics b.total Parenteral nutrition c.antitussive d.mycobacteria 83.tobramycin c.scabies e.com 111 .d.virus c.non of the above 82.B species is a.all of the above e.anticholinergics e.sun burns c.T.lymecycline e.psoriasis e.all cause constipation except a.acne vulgaris d.scabies b. Drug of choice in emergency lowering intraocular pressure a.congestive heart failure e.azelaic acid used for www.both B& D 86.Trandate® a.prometric-questions.physostigmine 89.used as antimuscarinic in urology treatment a.bethanecol b.angina pectoris b.disease that can cause edema a.it's alpha & beta blocker c.carbachol c.85.both A& B 87.it's used to treat diarrhea e.it's pure beta blocker d.Cialis® abcde- it's generic name is sildenafil it's generic name is tildenafil it's generic name is tadalafil it's phosphdiesterase inhibitor both B & D 88.it's generic name is labetolol b.bethanecol b-carbachol c-pilocarpine d-neostigmine e-physostigmine 90.pilocarpine d.renal failure c.diabetes mellitus d.neostigmine e.com 112 . all of the above 94.diarrhea b.antimuscarinic d.valproate e.all of the above 93.prolong action of local anesthetics d.antitussive e.constipation c.antispasmodic b.both A& B e.propantheline is a.all of the above e.increase contractility of heart c.side effect of metronidazole a.phenytoin b.all make GIT upset except a.anticholinergics c.prometric-questions.benzodiazepam d.propranolol b.com 113 .carbamazepine c.nor epinephrine a.phenobarbitol 95.a.mutagenicity d.acne vulgaris 91.dark brown urine e.azoles c.antacid d.drug that induce impotence is a.metallic taste b.cimetidine www.stimulate adrenergic receptors b.carcinogenicity c.non of the above 92. H.start with expiration take 2 puffs followed by rapid inspiration e.It's treated with mupirocin oint.carvdilol 98.prometric-questions.non of the above 97.peptic ulcer d.all of above e.hyperkalemia b.fungal infection c.it caused by s.nadolol e.gram positive bacteria b.safe to use with asthmatic patients a-propranolol b.non of the above 100.Impetigo is a.condition contraindicate to take spironolactone a.take 1 puff then 1 min &another puff then take water d.aureus or streptococci pyogenes d.d.viral infection www.atenolol c.timolol d.patient prescriped salbutamol inhaler 2 puffs every 6 hours you should tell him to a.all of the above 99.take 2 puffs after shake well c.com 114 .pylori b. plus oral cephalexin e.thiazide e.vitamin C enhance the activity of drugs used to treat a.infection of superficial layer of epidermis c.renal insufficiency c.take 1 puff then expire then another puff b.all of the above 96. non of the above e.all of the above www.d.com 115 .prometric-questions. OTC mean (a) Over the counter (b) Drug that can be dispensed without prescrepition (c) Drug that can not be dispensed without prescrepition (d) Narcotic drugs (E) Both A & B 3. Which of the following drug used in treatment of acne (a) Aspirin (b) Digitoxin (c) Erythromycin (d) Hydrochlorothiazide (E) Allopurinol 4. Which of the following drug used in treatment of epilepsy (a) Carbamazepine www.Exam model 6 1.com 116 . Which of the following drug not belong to (NSAIDs) (a) Aspirin (b) Ibuprofen (c) Ketoprofen (d) Dexamethasone (E) Diclofenac 6. Which of the following drug used in treat congestive heart failure (a) Isosorbid (b) Metronidazole (c) Amoxacillin (d) Mannitol (E) Non of the above 2. Patient suffer from peptic ulcer and want to take medicine for inflammatory Arthritis Which of the following medication should be recommended (a) Aspirin (b) Celecoxib (c) Ketoprofen (d) Ibuprofen (E) Indomethacin 5.prometric-questions. Generic name of vitamin A is (a) Retinol (b) Cyanocobalamine (c) Cholecalciferol (d) Thiamine (E) Pyridoxine 10.7. Which of the following drug inhibit activity of hepatic enzyme (a) Phenobarbital (b) Aspirin (c) Digitoxin (d) Cimetidine (E) Rifampicin 11.prometric-questions. Which of the following drug increase activity of hepatic enzyme (a) Phenytoin (b) Rifampin (c) Carbamazepine (d) Phenobarbital (E) All of above 12. Which of the following drug belong to H2 receptor antagonist (a) Rantidine (b) Loratadine (c) Celecoxib www. Mechanism of action of (Potassium sparing diuretics) is (a) Increase execreation of potassium in urine (b) Increase execreation of sodium and water in urine (c) decrease execreation of potassium in urine (d) Decrease execeation of calcium in urine (E) Both B&C 9.com 117 . (b) Phenytoin (c) Phenobarbital (d) Valporic acid (E) All of above Which of the following drug used in cancer chemotherapy (a) Ampicillin (b) Paracetamol (c) Cyclophosphamide (d) Phenytoin (E) Furosemide 8. Which of the following drug is not contraindicated with aspirin (a) Heparin (b) Warfarin (c) Gliclazide (d) Erythromycin www. Nitroglycerin used for (a) Angina pectoris (b) Sore throat (c) UTI (d) Hypertension (E) Non of above 18. Rantidine belong to (a) H1 receptor antagonist (b) Loop diuretic (c) H2 receptor antagonist (d) B1 receptor antagonist (E) Proton pumb inhibitors 15. Lorazepam used as (a) Anti inflammatory (b) tranquilizer (c) Anti epileptic (d) Anti-diabetic (E) Both B&C 14.(d) Histadine (E) omeprazole 13. Which of the following drug consider as immunosuppressant (a) Cyclosporin (b) Metotrexate (c) Azathioprine (d) Cyclophosphamide (E) All of above 17.com 118 .prometric-questions. Vitamin B12 is used in treat (a) Hypertension (b) Prenicious anemia (c) Sore throat (d) Hypotension (E) Gout 16. Which of the following drug is used in treate HSV (herpes) (a) Chlormphenicol (b) Amoxicillin (c) Aspirin (d) Acyclovir (E) Fluconazole www. One of your freinds called you about an inpatient case. Which of the following drops used in treatment glucoma (increase intra ocular pressure (a) Chlormphenicol (b) Dexamethasone (c) Pilocarpine (d) Atropine (E) Metformin 22. If you find in your pharmacy adrug with apparent contamination you must (a) till the productive company (b) till the pharmacist (c) till the hospital manager (d) do not dispense this patch (E) dispense this patch 21. Which of the following drug is used in treat gout (a) Allopurinol (b) Chlorpromazine (c) Colchicine (d) Minocycline (E) Both A & C 24.com 119 .(E) All of above 19.prometric-questions. Leucopenia is condition in which (a) Increase number of erythrocyte (b) decrease number of leukocyte (c) Increase number of leukocyte (d) decrease number of erythrocyte (E) change in all blood cells 23. What will you till him? (a) Guide him to ask the doctor (b) Do not answer (c) till him about the medication (d) all of the above (E) Non of above 20. prometric-questions. Which of the following drug used in treatment hypertension (a) Noradrenaline (b) Captopril (c) Verapamil (d) Both B & C (E) All of above www. Which of the following drug belong to corticosteroid (a) Aspirin (b) Hydrocortisone (c) Prednisolone (d) Bumetanide (E) Both B & C 27. Which of the following antibiotic consider stronger (a) Ampicillin (b) Amoxacillin (c) Benzylpenicillin (d) Augmentin (E) penicillin V 26.25.com 111 . Which of the following drug used in treatment TB (a) Rifampin (b) Phenytoin (c) Prednisolone (d) Aspirin (E) Amlodipine 30. Which of the following drug is contraindicated with asthmatic patient (a) Paracetamol (b) Aspirin (c) Cephalexin (d) Amoxicillin (E) Non of above 29. Which of the following is consider hepatotoxic drug (a) Alcohol (b) Paracetamol (c) Halothane (d) Ketoconazole (E) All of them 28. 2 g (c) 0.1 g (E) Non of above 34.2 L (c) 0.31. Which of the following drug is antidote for morphine (a) Captopril (b) Methadone (c) Naloxone (d) Codeine (E) N-acetyl cystine 37. Decigram is equal (a) 0.d mean www.i. Which of the following drug act as calcium channel blocker (a) Aspirin (b) Halothane (c) Verapamil (d) Hydrochlorothiazide (E) Propranolol 32.001 L (b) 0.1 L (E) Non of above 35. Hypokalemia mean (a) Increase sodium in human body (b) decrease sodium in human body (c) increase potassium in human body (d) Decrease calcium in human body (E) None of them 33.001 g (b) 0.6 L (d) 0.6 g (d) 0. q. Acyclovir used for (a) HSV encephalitis (b) Genital herpes infections (c) Headache (d) Hypertension (E) Both A & B 36.prometric-questions.com 111 . Decilitre is equal (a) 0. m. Expiraion date of one drug is 8/2006 (a) 1/9/2006 (b) 1/8/2006 (c) 31/8/2006 (d) 15/8/2006 (E) 31/7/2006 42.prometric-questions.d mean (a) Three time daily (b) twice daily (c) once daily (d) four time daily (E) at bed time 39. t. Patient take drug A (250 ml/5mg)..(a) (b) (c) (d) (E) Three time daily twice daily once daily four time daily at bed time 38. Patient use (Augmentin 250 mg Tablets) three time daily for one week How many tablet this patient will consume (a) 20 tablet (b) 21 tablet (c) 18 tablet (d) 9 tablet (E) 24 tablet 40.com 112 .i. One of the following substance used in treatment of many toxic cases (a) Aspirin (b) Activated charcoal (c) Timolol (d) Paracetamol (E) Diltiazem 41. 750 ml p. he take 1000 ml a.m He will receive in 20 days …. gm (a) 700 gm (b) 1250 gm (c) 1000 gm (d) 600 gm (E) 900 gm www. 12 (d) 14 .43.com 113 .16 (b) 11 . The generic name of (Prozac)® is (a) Verapamil (b) Timolol (c) Fluoxetine (d) Omperazole (E) flucloxacillin 46.10 (c) 5 .prometric-questions. Percent Haemoglobin in man (g/dl) equal (a) 12 .16 (E) 14-18 www.15 (c) 8 . Percent Haemoglobin in woman (g/dl) equal (a) 10 ..10 (d) 12 . phone you asking for dispensing additive drug without prescription What will you do (a) dispense the drug after ensuring patient state (b) dispense the drug without ensuring patient state (c) dispense the drug after ensuring doctor I.12 (b) 8 . Antiseptic contain 150 ml of active ingrident with supply label 5mg for 10 ml How many mg of active ingrident in 150 ml? (a) 75 mg (b) 15 mg (c) 1500 mg (d) 50 mg (E) 100 mg 45. The generic name of (flagyl)® is (a) Mebendazole (b) Amoxicillin (c) Phenytoin (d) Metronidazole (E) Spironolactone 47. Doctor ….18 (E) 10-12 48. (d) do not dispense the drug without prescription (E) Non of above 44.D. Which of the following drug is used for hypertension (a) Paracetamol (b) Diltiazem (c) Ibuprofen (d) Salbutamol (E) Acyclovir www. Insulin preserved in (a) 5 centigrade (b) 20 centigrade (c) -10 centigrade (d) 15 centigrade (E) 10 centigrade 51.49. What is the drug of choice for headache in asthmatic patient ? (a) Aspirin (b) Salbutamol (c) Diclofenac (d) Paracetamol (E) Ketotifen 54. What is happen to elderly patient take (Glibenclamide) and advised by friend To take (Glipizide) too (a) hyperglycemia (b) hypoglycemia (c) hypotension (d) No effect on blood pressure (E) No effect on blood sugar 53. Insulin preserved in (a) room temperature (b) high temperature (c) refregerator temperature (d) freezing temperature (E) preserved at any temperature 50.prometric-questions. Hypercalcemia is (a) Increase potassium in blood (b) Increase calcium in blood (c) decrease calcium in blood (d) Increase sodium in blood (E) decrease magnesium in blood 52.com 114 . Blockers (d) αblocker (E) α2 -agonist 56. Atenolol belong to (a) β blocker (b) β1 . Ordinary prescription contain (a) Morphine (b) Hypnotics (c) Pethidine (d) Acetaminophen (E) None of the above 60. Which of the following drug used in treatment HIV (AIDS) (a) Zidovudine (b) Verapamil (c) Diltiazem (d) Prednisolone (E) All of above www.prometric-questions.com 115 .Blockers (c) β2 .55.5 – 5 meq/L (E) 10. Percent of potassium in blood (a) 20 meq/L (b) 1 meq/L (c) 50 meq/L (d) 3. Which of the following consider a source of entering information to computer (a) Mouse (b) Keyboard (c) Scanner (d) All of the above (E) Non of above 58.145 meq\L 57. Which of the following consider a source to exit information from computer (a) screen (b) Audio video (c) Printer (d) All of the above (E) Non of above 59. What is instruction you should till patient on (Diclofenac 50 mg) (a) Take it before meal (b) Drink more tea and coffee (c) Take it after meal (d) Drink more citrus fruit (E) Don't sleep after taking drug 62.i. Which of the following drug not belong to (NSAIDs) (a) Aspirin (b) Ibuprofen (c) Dexamethasone (d) Ketoprofen (E) Mefenamic acid 66.com 116 . Female patient on (Neostigmine) want to be pregnant How long should she separate between pregnancy and drug? (a) 2 week (b) 2 day (c) 2 year (d) 2 month (E) it's safe to take this drug during pregnancy 64.d.i. ×1 3 days× b.61.d. ×1 how many tablet you will dispense (a) 9 (b) 15 (c) 18 (d) 12 (E) 21 63. ×1 3 days × q. (Ganciclovir) used for (a) Virus infection (b) Bacteria infection (c) asthma www. Malaria transmitted by (a) Male anopheles mosquito (b) Female anopheles mosquito (c) Rats (d) Sand fly (E) Sexually 65. (Prednisolone) administer as 3 days× t.prometric-questions.d. diagnosis and his room number (d) Do not till him any thing www. What will your answer? (a) Till him about drug (b) Till him about drug and diagnosis (c) Till him about drug . Which of the following drug belong to OTC : (a) Tegretol ® (b) Augmentin ® (c) Valium ® (d) Panadol ® (E) None of the above 70. OTC include (a) Antibiotic (b) tranquilizer (c) Laxative (d) Antiepileptic (E) OHG drugs 68. Which of the following drug can used for (Giardiasis) (a) Amoxicillin (b) Metronidazole (c) Diosmin (d) Ampicillin (E) Non of above 71. OTC include (a) Ibuprofen (b) Diazepam (c) Paracetamol (d) Verapamil (E) Both A &C 69.com 117 .prometric-questions. One of your friend ask for some information about inpatient.(d) rheumatism (E) Fungal infection 67. Warfarin antidote is (a) Aspirin (b) Vitamin K (c) Vitamin D (d) Vitamin E (E) Both A& B 72. Generaly antibiotics are stored in (a) Cold place (b) Away from light (c) Room temperature (d) According to box instruction (E) under 25° C www. Mannitol has the following charachter (a) I.com 118 . Antihypertensive of choice in pregnancy is (a) Methyl dopa (b) Enalapril (c) Atenolol (d) Captopril (E) Amlodipine 78. Vaccines preserved in temperature………… (a) Room temperature (b) Buttom shelf of refregerator (c) Upper shelf of refregerator (under frezer) (d) Freezing temperature (E) Oven temperature 76. Urea used for treatment of (a) Asthma (b) Increase intracranial pressure (c) diuretic (d) Hypertension (E) Both B & C 77.V can't taken orally (b) Decrease intracranial pressure (c) Decrease intraocular pressure (d) It's osmotic diuretics (E) All of the above 75. After you dispense a prescription you find out a mistake What you will you do? (a) Silence not aware (b) Till hospital manager (c) Till pharmacist (d) Till patient immediately (E) Non of above 74.(E) Non of above 73.prometric-questions. Blockers (d) β.agonist (d) β1 Blockers (E) CCBs 82. Spironolactone belong to (a) Antibiotics (b) Antihistamines (c) Diuretics (d) Sedatives (E) Calcium channel blockers 83.Blockers (c) α.com 119 .prometric-questions.Blockers (b) Antibiotics (c) α. Propranolol belong to (a) β .Blockers (E) Cytotoxic drugs 80. Vitamine (B1) generic name is (a) Retinol (b) Ascorbic acid (c) Phytomenadione (d) Thiamine (E) Riboflavin www.79.agonist (b) β. (Tetracycline) belong to (a) H 2 . Spironolactone belong to (a) Thiazide diuretics (b) Osmotic diuretics (c) Potassium sparing diuretics (d) Loop diuretics (E) Carbonic anhydrase inhibitors 84. Which of the following belong to antihypertensive (a) Inderal ® (b) Buscopan ® (c) Flagyl ® (d) Diamicron ® (E) Zovirax ® 81. Which of the following drug used in treatment AIDS (a) Zocor® (b) Zovirax® (c) Zaditine® (d) Zidovudine® (E) Zinnat® 90.prometric-questions. Duration of treatment for TB is (a) 2 month (b) 4 month (c) 6-9 month (d) 2 years (E) 4 years 88. Capoten ® it's generic name is (a) Enalapril (b) Verapamil (c) Atenolol (d) Captopril (E) Chorothiazide 89. Vitamine (K) generic name is (a) Retinol (b) Ascorbic acid (c) Phytomenadione (d) Niacin (E) Tocopherol 87.com 121 .85. www. Which of the following drug used to manage hypertension (a) Noradrenaline (b) Captopril (c) Verapamil (d) Ofloxacin (E) Both B & C Which of the following drug consider diuretic (a) Aspirin 91. Vitamine (B2) generic name is (a) Retinol (b) Ascorbic acid (c) Phytomenadione (d) Riboflavin (E) Thiamine 86. Which of the following route give 100% bioavailability (a) SC (b) IM (c) Oral (d) IV (E) ID 97. (b) Halothane (c) Hydrochlorothiazide (d) Verapamil (E) Florouracil Rifampicin turn urine color into (a) Red (b) Yellow (c) White (d) Blue (E) No change in its color 93. Vitamine (C) generic name is (a) Retinol (b) Ascorbic acid (c) Phytomenadione (d) Riboflavin (E) Menadione 95.prometric-questions.C) of Ascariasis is (a) Metronidazole (b) Verapamil (c) Paracetamol (d) Mebendazole (E) Chloroquine 96.com 121 . Drug of choice (D.92. Acyclovir used for (a) Rheumatism (b) Bacteria infection (c) Parasitic infection (d) Virus infection (E) Fungal infection 94.O. Hepatitis B vaccination per year is (a) 3 time (b) 2 time (c) 1 time www. com 122 .prometric-questions. Fat soluble vitamins include (a) A & D (b) A & C (c) B& K (d) B &C (E) Non of above 99. Water soluble vitamins include (a) A & C (b) D & K (c) B & C (d) B & D (E) E 100 Maximum dose of (Paracetamol) per day is (a) 10 gram (b) 4 mg (c) 3 gram (d) 4 gram (E) 500 mg www.(d) 5 time (E) Every 2 monthes 98. com 123 . Maximum dose of (Paracetamol 500 mg tablet) for adult in day (a) 10 tablet (b) 7 tablet (c) 8 tablet (d) 4 tablet (E) 2 tablet 2.Exam model 7 1. Barium sulfate is used for (a) Treatment constipation (b) Treatment diarrhea (c) Treatment dry cough (d) In radiology diagnosis (E) treatment of DM 3.prometric-questions. Maximum dose of (Captopril) is (a) 10 mg (b) 75 mg (c) 80 mg (d) 150 mg (E) 50 mg 4. Maximum dose of (Captopril 50 mg ) is (a) 4 tablet (b) 3 tablet (c) 10 tablet (d) 6 tablet (E) 2 tablet 5. The first choice for Type 2 diabetes (a) Analgesics (b) Insulin (c) NSAIDs www. To prevent absorbtion of toxic substance we can use (a) Activated charcoal (b) Captopril (c) Loratadine (d) Aspirin (E) furosemide 6. com 124 . The generic name of (Voltaren)® is (a) Aspirin (b) Diosmin (c) Diclofenac (d) Piroxicam www. Cefaclor belong to (a) 1st generation Cephalosporines (b) 2nd generation Cephalosporines (c) 3rd generation Cephalosporines (d) 4th generation Cephalosporines (E) 2nd generation quinolones 12. The first choice for Type 1 diabetes (a) Analgesics (b) Sulfonylurea (c) NSAIDs (d) Insulin (E) H2 blockers 8. Cefaclor belong to (a) Thiazide diuretics (b) Penicillins (c) Potassium sparing diuretics (d) Cephalosporines (E) NSAIDs 11. Which of the following drug can΄t be used during pregnancy (a) Paracetamol (b) Amoxicillin (c) Cephalexin (d) Ciprofloxacillin (E) Erythromycin 10.(d) (E) Sulfonylurea H2 blockers 7. (Theophylline) used as (a) Bronchoconstrictor (b) Antihistaminic (c) Antiviral (d) Brochdilator (E) Anti tussive 9.prometric-questions. prometric-questions. (Zantac)® generic name is (a) Rantidine (b) Cimetidine (c) Rantidol (d) Famotidine (E) Omeprazole 15. Which of the following drug is hepatotoxic (a) Indometacin (b) Aspirin (c) Ibuprofen (d) Paracetamol (E) Chlorothazide 17. Which of the following drug is contraindicated with renal failure (a) Tetracycline (b) Gentamycin (c) Ampicillin (d) Ketoconazole (E) Both A & B 18. (Voltaren)® uses are (a) Analgesic fot teeth pain (b) Anti inflammatory for arthritis (c) Analgesic for headache (d) It's NSAIDs (E) All of them 14.(E) Domperidone 13.com 125 . (Zantac)® used for (a) Peptic ulcer (b) Hyperacidity (c) Hypertension (d) Diarrhea (E) Both A & B 16. (Sumatriptan) is used for (a) Migraine (b) CHF (c) Hypertension (d) Angina treatment (E) Gout www. (Nitrofurantoin) is used for (a) UTI (b) renal failure (c) analgesics (d) TB (E) Leprosy 20.prometric-questions. Which of the following drug is used in treate M. Which of the following drug is used in treat dehydration because of diarrhea (a) Aspirin (b) ORS ( oral rehydration solution ) (c) Furosemide (d) Hydrochlorothiazide (E) Kaloin 24.com 126 .19. Cimetidine is used for (a) peptic ulcer (b) prophylaxis from peptic ulcer (c) duodenal ulcer (d) GERD disease (E) all of them 21. (Ventolin) )® generic name is (a) Aspirin (b) Cimetidine (c) Diclofenac (d) Salbutamol (E) Paracetamol 22. (Ventolin) )® is used for (a) Migraine (b) Hypotension (c) Brochial asthma (d) Headache (E) Hypertension 23.TB (a) Rifampicin (b) Ethambutol (c) Isoniazide (d) Streptomycin (E) All of them www. com 127 . (Nifedipine) it'strade name is www. Which of the following used for Thyrotoxicosis (a) Levothyroxine sodium (b) Iodine (c) Radioactive iodine (d) Liotrix (E) Both B & C 29. Which of the following used for hyperthyroidism (a) Propylthiouracil (b) Carbimazole (c) Radioactive iodine (d) Lugol iodine (E) All of them 28. Which of the following used for thyroid deficiency (a) Liothyronine (b) Levothyroxine sodium (c) Thyroxine sodium (d) Liotrix (E) All of them 27. (Gliclazide) it's trade name is (a) Diamicron® (b) Amoxil® (c) Minidiab® (d) Ventolin® (E) Glucophage® 31. (Gliclazide) is used for management of (a) Hypertension (b) Hyperglycemia (c) Hypoglycemia (d) Migraine (E) Hypotension 30. Which of the following used for thyroid deficiency (a) Aspirin (b) Carbimazole (c) Thyroxine sodium (d) Radioactive iodine (E) Lugol iodine 26.25.prometric-questions. (a) Tenormin® (b) Ateno® (c) Adalat® (d) Ventolin® (E) Edemix® 32. Which of the following formula belong to liquid dosage form (a) Solutions (b) Powders (c) Suppsitories (d) Tablets (E) Capsules 37. Which of the following formula belong to solid dosage form (a) Tablets (b) Capsules (c) Suspensions (d) Syrups (E) Both A & B 36. (Augmentin)® generic name is (a) Amoxicillin / Paracetamol (b) Amoxicillin / Potassium clavulanate (c) Benzylpenicillin / Potassium clavulanate (d) Ampicillin / Potassium clavulanate (E) Amoxicilli / Sulbactam 33. (Clarithromycin) it's trade name is (a) Ventolin® www. (Co-trimoxazole) is composed of (a) Trimethoprim (b) Sulfamethoxazole (c) Salbutamol (d) Trimethoprim / Sulfamethoxazole (E) Non of above 34.com 128 .prometric-questions. Which of the following drug belong to (Aminoglycosides) (a) Amikacin (b) Neomycin (c) Streptomycin (d) Kanamycin (E) All of the above 35. (b) (c) (d) (E) Amoxil® Klacid® Vibramycin® Zinnat® 38. Which of the following drug consider (antidote) for (heparin) (a) Warfarin (b) Protamine sulfate (c) Phenindione (d) Aspirin (E) Vitamin K 39. (Acetazolamide) it's trade name (a) Lasix® (b) Diamox® (c) Aldactone® (d) Bumex® (E) Non of above 42.com 129 . (Sol.) abbreviation mean (a) Suppository (b) Suspension www. (Vitamin B 6) scientific name is (a) Niacin (b) Riboflavin (c) Pyridoxine (d) Thiamine (E) Cobolamie 40.) abbreviation mean (a) Suppository (b) Suspension (c) Solution (d) Syrup ( E) Solid dosage form 43.prometric-questions. (Susp. (Acetazolamide) used for (a) Glaucoma (b) Hypotension (c) Asthma (d) Diarrhea (E) Hepatitis 41. (Bid) mean (a) Once Daily (b) Twice Daily (c) Three time Daily (d) Four time Daily (E) At bed time 48. (sos) mean (a) don not repeat (b) Four time Daily (c) Twice Daily www.(c) (d) (E) Solution Syrup Solid dosage form 44. Who can not use aspirin (contraindicated) (a) Angina (b) Gastric ulcer (c) Hemophilia (d) Headace (E) Both B & C 46. (IM) mean (a) Intravenous (b) Intramuscular (c) Subcutaneous (d) Intradermal (E) Intra-arterial 49. (Amoxil)® generic name (a) Amoxicillin / Potassium clavulanate (b) Ampicillin (c) Flucloxacillin (d) Amoxicillin (E) Amoxicillin/Sulbactam 47.prometric-questions.com 131 . (Nasal drops) mean drop for (a) Eye (b) Nose (c) Ear (d) Mouse (E) Both A & C 45. 9) mean (a) 0. (Sodium chloride % 0. (Metoclopramide) belong to (a) Antiemetic (b) Antiepileptic (c) Antihistaminic (d) Anti diarrheal www.9 gram Sodium chloride per 100 ml solvent (E) 0. (Aspirin)® generic name is (a) Acetylbutyric acid (b) Paracetamol (c) Mefenamic acid (d) Acetylsalcylic acid (E) Acetaminophen 55. (Claritine)® used as (a) Antihypertensive (b) Antirheumatic (c) Antihistaminic (d) Antibiotic (E) Diuretics 54. (Dextrose 5%) means (a) 5 mg dextrose per 100 ml solvent (b) 5 gram dextrose per 1000 ml solvent (c) 5 gram dextrose per 100 ml solvent (d) 5 kilogram dextrose per 100 ml solvent (E) 5 mg dextrose per 1000ml solvent 51.com 131 .prometric-questions. (Claritine)®it's generic name (a) Histadine (b) Loratadine (c) Chorpheniramine (d) Adrenaline (E) Chlorothiazide 53.9 mg Sodium chloride per 1000 ml solvent 52.9 gram Sodium chloride per 1000 ml solvent (d) 0.9 kilogram Sodium chloride per 100 ml solvent (c) 0.9 mg Sodium chloride per 100 ml solvent (b) 0.(d) (E) as needed (when necessary) Before meals 50. (Buscopan)® it's generic name is (a) Atropine (b) Hyoscine (Scopolamine) (c) Atenolol (d) Pilocarpine (E) Paracetamol www.prometric-questions. Which of the following drug can be used for rheumatic patient (a) Ibuprofen (b) Diclofenac (c) Indometacin (d) Ketoprofen (E) All of the above 60. Which of the following drug can be used in management constipation (a) Glycerin suppositories® (b) Duphlac syrup® (c) Dulcolax® (d) Senalax® (E) All of the above 59. (Glucophage)®it's generic name is (a) Glibenclamide (b) Tolbutamide (c) Metformin (d) Gliclazide (E) Glimepiride 61. (E) Analgesics (Metoclopramide) it's trade name is (a) Motinorm® (b) Motilium® (c) Primperan® (d) Amoxil® (E) Mycogel® 57.56.com 132 . Which of the following drug can be used in management constipation (a) Diclofenac (b) Glycerin suppositories (c) Ibuprofen (d) Paracetamol ( E) Loperamide 58. Which of the following drug belong to (Penicillins) (a) Amoxicillin (b) Ampicillin (c) Flucloxacillin (d) Cloxacillin (E) All of the above 66.com 133 .prometric-questions. (Cephalexin) it's (Trade name) is (a) Keflex® (b) Velosef® (c) Amoxil® (d) Duricef® (E) Cidophage® 64.62. (Allopurinol) it's Trade name is (a) Profenid® (b) Ketofan® (c) Zyloric® (d) Voltaren® (E) Cholchicine® 63. (Lasix)®it's generic name is (a) Captopril (b) Atenolol (c) Furosemide (d) Hydrochlorothiazide (E) Bumetaide 68. Convert temperature 59 Fahrenheit to Celsius (a) 25 (b) 12 (c) 15 (d) 20 (E) 10 67. (Captopril)it's (Trade name) is (a) Tenormin® (b) Capoten® (c) Lasix® (d) Adalat® (E) Avadia® 65. (Lasix)® used as www. (Simvastatin) it's trade name is (a) Zocor® (b) Amoxil® (c) Mevacor® (d) Lipitor® (E) Ator® 70.prometric-questions. (Simvastatin) used for (a) Decrease blood sugar www. Warfarin antidote (a) Aspirin (b) Vitamin E (c) Vitamin D (d) Vitamin K (E) Protamine sulfate 72. (Questran)®it's generic name is (a) Cholestyramine A (b) Simvastatin (c) Atrovastatin (d) Niacin (E) Clostipol 74.(a) (b) (c) (d) (E) Diuretic Antirheumatic Antidiarrheal Antibiotics Both A &C 69.com 134 . (Nizoral)®it's generic name is (a) Ketoconazole (b) Fluconazole (c) Miconazole (d) Glibenclamide (E) Nizatidine 71. Which of the following drug belong to Long acting (Tetracyclines) (a) Chlortetracycline (b) Doxycycline (c) Minocycline (d) Erythromycin (E) Both B & C 73. (Brufen)®it's generic name is (a) Mefenamic acid (b) Ketoprofen (c) Diclofenac (d) Ibuprofen (E) Mefenamic acid 78.com 135 . What is the text books should be available in pharmacy (a) Martindale (b) British national formulary (c) Middle east medical index (d) America pharmacopia (E) all of the above 80. (Zovirax)®it's generic name is (a) Interferon (b) Zidovudine (c) Acyclovir (d) Oxytetracycline (E) Nystatin 77. (Aldomet)®it's generic name is (a) Verapamil (b) Atenolol (c) Captopril (d) Methyl dopa (E) Propranolol 76. (Daonil)®it's generic name is (a) Paracetamol (b) Gliclazide (c) Metformin (d) Glipenclamide (E) Glimipride 79.prometric-questions.(b) Decrease calcium in blood (c) Antihyperlipidemic (d) Decrease sodium in blood (E) Decrease blood pressure 75. Which of the following drug belong to Second generation Cephalosporines (a) Cephalexin www. Which of the following drug belong to third generation Cephalosporines (a) Cefoperazone (b) Cefotaxime (c) Cefixime (d) Ceftriaxone (E) all of the above 83.com 136 .(b) (c) (d) (E) Cefuroxime Cephadroxil Cefipime All of above 81.prometric-questions. Which of the following drug used in treatment hypertension (a) Paracetamol (b) Ibuprofen www. Which of the following drug belong to first generation Cephalosporines (a) Cephalexin (b) Cephadroxil (c) Cephazolin (d) Cephradine (E) All of above 82. Aspirin can be used as (a) Analgesic (b) Antipyretic (c) Anti inflammatory (d) Anti-platlet (E) All of the above 84. Which of the following drug used in treatment epilepsy (a) Phenytoin (b) Diclofenac (c) Heparin (d) Atenolol (E) Metformin 86. (Metformin) used for treatment of (a) Hypertension (b) Hypotension (c) Hyperglycemia (d) Hypoglycemia (E) Hyperlipidemia 85. (c) Heparin (d) Diltiazem (E) Famotidine 87. (Cefipime) belong to (a) 1st generation cephalosporin (b) 2nd generation cephalosporin (c) 3rd generation cephalosporin (d) 4th generation cephalosporin (E) 4th generation quinolones 88. Which of the following drug does not used in treat amebiasis (a) Diloxanide Furoate (b) Gentamicin (c) Metronidazole (d) Iodoquinol (E) Emetine 90.prometric-questions. Which of the following drug does not belong to (Tetracyclines) (a) Chlortetracycline (b) Tetracycline (c) Doxycycline (d) Clindamycin (E) Minocycline 89.com 137 . Patient suffer from wheezing and want to recipe prescription of (inderal)® tablet (a) Prescripe it (b) Prescripe antiasthmatic drug www. All of the following are consider insulin side effect (a) Hypersensitivity (b) Hypoglycemic coma (c) Atrophy at site of injection (d) Weight gain (E) All of them are true 91. Which of the following consider antivirus (a) Acyclovir (b) Interferons (c) Amantadine (d) Zidovidine (E) All of the above 92. Sources of insulin include (a) Cows (b) Pigs (c) Escherichia coli (E.prometric-questions. Which of the following drug used for prostatitis (a) Aldosterone (b) Insulin (c) Finasteride (d) Paracetamol (E) Cimetidine 95. ASA &Water in the same formula the product is (a) Emulsion (b) Elixir (c) Suspension www.(c) Ask patient about his illness (d) Do not prescripe prescription and ask him to return to physician (E) Non of above 93. Which of the following consider nephrotoxic drug (a) Gentamycin (b) Tetracycline (c) Oxytetracycline (d) Kanamycin (E) All of the above 94. All consider true about Tetracycline except:(a) Orally active (b) Bactericidal (c) Use for treat acne (d) Excreted in urine (E) All are true 97.com 138 . coli) (d) Human (E) All of the above 96. If Olive oil. Type 2 diabetes characterized by (a) Inability for producing insulin (b) Insufficient amount of produced insulin (c) Decrease sensitivity of insulin receptor (d) Occurs during pregnacy (E) Both B & C 98. 99. (d) Solution (E) Paste What the concenteration of NaCl in Dextrose 5 % half normal saline, D5 1/ 2 NS (a) 1.8 % (b) 0.9 % (c) 0.225 % (d) 0.45 % (E) 5 % 100 Which of the following is the fastest dosage form (a) IM injection (b) ID injection (c) IV injection SC injection (d) (E) IA injection www.prometric-questions.com 139 Exam model 8 1. (Simvastatin) according to FDA consider (Pregnancy Category x) (a) Can be used during first trimester (b) Can be used under medical supervision (c) Absolutely contraindicated (d) Safely used during pregnancy (E) Can be used after first trimester 2. Antidote for (Digoxin) toxicity is (a) IV Normal Saline (b) Digibind (c) Activated Charcoal (d) Digitoxin (E) Protamine sulfate 3. The site of (Intra-thecal injection ) is (a) Joint (b) Skin (c) IntraMusclular (d) Directly in spinal cord (E) Directly in blood veins 4. Which of the following cause intravenous incompatibility if taken with (Dextrose) (a) Insulin (b) Cefazolin (c) Ceftriaxone (d) Phenytoin (E) All of above 5. Mechanism of (Drug-Drug interactions) include (a) Enzyme induction (b) Formation of unabsorbed complex (c) Plasma protein displacement (d) Enzyme inhibitors (E) All of the above 6. One of the following is (Natural emulsifying agent) (a) Lactose (b) Polysorbate (c) Acacia www.prometric-questions.com 141 (d) (E) Sorbitol Glycerin 7. PH for ocular preparation range from (a) 2 - 3 (b) 4 - 6 (c) 6 - 8 (d) > 8 (E) 5.5 8. 1 grain equal (a) 50 Gram (b) 10 Gram (c) 0.60 Gram (d) 0.065 Gram (E) Non af above 9. How many gram needed from water to prepare 160 gram from potassium acetate (5 % W/W) (a) 100 (b) 130 (c) 135 (d) 152 (E) 125 10. How many gram needed from substance (X) to prepare 30 ml solution (1:1000) (a) 10 mg (b) 30 mg (c) 300 mg (d) 0.03 mg (E) 1000 mg 11. Female (22 years old ) with advanced acne recommended to take (Roaccutance) what is the procedure you do before dispence this drug (a) Identify her weight (b) Ask if she is pregnant (c) Dispense the drug without precautious (d) Ask her doctor to change this drug (E) Don't dispense this drug 12. (QOD) abbreviation means (a) Every four days (b) Four times a day www.prometric-questions.com 141 (c) (d) (E) Every other day Every day At bed time 13. (Cerivastatin) with drawn from saudi because mortal effect on (a) Muscles (b) Bone (c) Blood (d) C.N.S (E) Liver 14. (cytotec) was restricted to use because (a) Decrease patient weight (b) Cause patient to suicide (c) Cause mythenia gravis (d) Cause Abortion (E) Cause cardiac shock 15. (Ibuprofen) maximum dose is (a) 800 mg (b) 3000 mg (c) 1600 mg (d) 3200 mg (E) 600 mg 16. According to ministery of health instruction, narcotic drug prescreption should be dispenced only if (a) Clearly contain patient name, number (b) Clearly contain doctor name, number and signature (c) Dispense during 3 days only from prescription date (d) Dispense the exact drug wiithout alternatives (E) All of the above 17. Which of the following not belong to (NSAIDs) (a) Tilcotil (b) Parafon (c) Naproxen (d) Ibuprofen (E) Indomethacin 18. Patient on (Amiloride) and prescribed to take (Captopril) what the expected side effect will happen ? (a) Hyperkalemia www.prometric-questions.com 142 (b) Hyponatremia (c) Hypertension (d) Hypercalcemia (E) Hypermagnesemia 19. (Cefuroxime) belong to (a) Penicillins (b) Quinolones (c) First generation cephalosporin (d) Second generation cephalosporin (E) Sulphonamide 20. Which of the following will cause constipation as side effect (a) Augmentin (b) Multivitamins (c) Morphine (d) Diphenhydramine (E) Paracetamol 21. Infants ( 2 month old ) suffer from fever and nasal congestion what will you advice his father (a) Ask him to take (Paracetamol & Actifed) (b) Ignore the case (c) Put him under supervision for 48 hr. (d) Advise him to take the infant to hospital (E) Advise him to put cold cotton on baby face 22. (Micromedex) is (a) New antihypertensive drug (b) New antidepressant drug (c) New medicine book (d) Computer programe contain drugs name, classification, uses (E) New pharmacological book 23. (Viagra)® generic name is (a) Atenolol (b) Sildenafil (c) Amoxicillin (d) Silfinadil (E) Propranolol 24. What is the proper question to patient dispence ( Viagra )® (a) How old are you? www.prometric-questions.com 143 (b) What is your name? (c) Only Dispense the drug (d) If he take nitroglycerin (E) If he is a diabetic patient 25. All of tthem consider OTC drug except (a) Tegretol (b) Bisacodyl (c) Molax (d) Aspirin (E) Paracetamol 26. Absorbtion of (Tetracycline) with (Al+++ & Fe++) lead to (a) Active absorbable complex (b) Inactive absorbable complex (c) Active less absorbable complex (d) Inactive in absorbable complex (E) No interaction between them 27. Patient on tetracycline what is your advice about drinking milk? (a) Separate between them by 10 minute (b) Nothing is important (c) Take them with each other (d) Separate between them by at least 2 hour (E) No interaction between them 28. Which of the following (Insulin) can be taken intravenously (a) Lente insulin (b) NPH insulin (c) Human mixtard 30/70 insulin (d) Regular insulin (E) All of above 29. Which of the following (Insulin) has duration of (12 – 24 ) hr. (a) Lente insulin (b) Insulin Lispro (c) Human mixtard 30/70 insulin (d) Regular insulin (E) NPH insulin 30. The most important side effect of insulin over dose (a) Skin atrophy at site of injection (b) Hypoglycemia www.prometric-questions.com 144 (c) Hypertension (d) Hyperglycemia (E) Hypotension 31. The most caustive organism of (UTI) is (a) Amoeba (b) Gram positive & negative microorganisms (c) Gram negative microorganisms (d) Gram positive microorganisms (E) Psudomonas 32. All of them belong to (Macrolides) except (a) Clindamycin (b) Erythromycin (c) Azithromycin (d) Clarithromycin (E) Non of above 33. All of them belong to (ACE inhibitors) except (a) Captopril (b) Lisonopril (c) Ramipril (d) Nifedipine (E) Enalopril 34. Paracetamol dose for pediatric ( 5 years old ) (a) 500 mg every 6 h (b) 500 mg every 8 h (c) 10 – 15 mg/Kg every 4 – 6 h a day (d) 700 mg every 10 h (E) 4 gm per day 35. What is the recommended dose foe vitamin A deficiency? (a) 500 IU (b) 100 IU (c) 10 IU (d) 50000 IU (E) 10000 IU 36. (Valproic acid) used for treatment of (a) Anemia (b) Epilepsy (c) Depression www.prometric-questions.com 145 (d) Headache (E) Hypertension 37. Thrombocytopenia mean: (a) Decrease number of red blood cells (b) Decrease number of white blood cells (c) Increase number of platelet (d) Decrease number of platelets (E) Decrease number of lymphocyte 38. Which of the following drug belong to (Ca-Channel Blockers) ? (a) Captopril (b) Diltiazem (c) Atenolol (d) Sotalol (E) Amiloride 39. Which of the following drug belong to local anathesia (a) Lidocaine (b) Spironolactone (c) Insulin (d) Ampicillin (E) Verapamil 40. One of the following substance used as antidote for paracetamol toxicity (a) Aspirin (b) Ampicillin (c) Atenolol (d) N-acetylcysteine (E) Protamine sulfate 41. Which of the following drug not contraindicated with pregnancy (a) Captopril (b) Ciprofloxacin (c) Tetracycline (d) Amoxicillin (E) Nifidipine 42. Regular insulin is characterized by (a) Clear (b) Colorless (c) Watery (d) Non of above www.prometric-questions.com 146 (E) All of the above 43. Atropine belong to (a) choline esterase inhibitor (b) direct acting cholinomimetic (c) sympatholytic drug (d) cholinergic agonist ( antimuscarinic ) (E) Neuro-muscular blocker 44. (Benzyl peroxide) uses (a) Expectorant (b) Anti-emetics ( chemically induced vomiting in cancer chemotherapy ) (c) Acne preparation (d) Migraine (E) Hyper tension 45. (Ondasetron) uses (a) Expectorant (b) Anti-emetics ( chemically induced vomiting in cancer chemotherapy ) (c) Acne preparation (d) Migraine (E) Hypertension 46. Preparation containing NaCl 10 % with water this pharmaceutical form is (a) Lotion (b) Suspension (c) Solution (d) Emulsion (E) Paste 47. Which of the following drug belong to catecholamine (a) Epinephrine (b) Norepinrphrine (c) Dopamine (d) Both A& B (E) All of the above 48. Furosemide belong to (a) Thiazide diuretics (b) Osmotic diuretics (c) Loop diuretics (d) Potassium sparing diuretics (E) Carbonic anhydrase inhibitors www.prometric-questions.com 147 49. Generic name of Zestril® is (a) Lisinopril (b) Enalopril (c) Ramipril (d) Captopril (E) None of them 50. Generic name of tritace® is (a) Lisinopril (b) Enalopril (c) Ramipril (d) Atenolol (E) None of them 51. The ……. Route offer instantaneous and complete absorbtion (a) Topical (b) Oral (c) I.V (d) I.M (E) Vaginal 52. Drugs administered by ……. Are exposed to first pass metabolism (a) Topically (b) Orally (c) I.V (d) I.M (E) Rectally 53. The drug may be metabolized by (a) Liver (b) Kidney (c) Intestine (d) Both A & B (E) None of the above 54. The drug and its metabolites are eliminated from body in (a) Urine (b) Feces (c) Bile (d) Sweet (E) All of the above 55. The therapeutic index (TI) can be defined as : www.prometric-questions.com 148 prometric-questions. Bioavailability is defined as (a) The action of the body on the drug (b) Rate & extent to which drug enters systemic circulation (c) Remove the drug from the body (d) The action of drug on the body (E) All of the above 59.effective dose (c) Toxic + effective dose (d) Toxic × effective dose (E) None of the above 56. If 100 mg of the drug is administered orally and 70mg of this drug is absorbed unchanged the bioavailability is (a) 100 % (b) 10 % (c) 70 % (d) 30 % (E) 90 % 60.com 149 .(a) Toxic / effective dose (b) Toxic . Pharmacokinetics include (a) Absorption (b) Metabolism (c) Execretion (d) distribution (E) All of the above 58. Which one of these is aprodrug? (a) Ampicillin (b) Erythromycin (c) Levodopa (d) Ibuprofen (E) All of the above 57. The nervous system is divided into www. Total body clerancy is the sum of the clerance from : (a) Hepatic (b) Renal (c) Pulmonary (d) All of the above (E) Non of above 61. Epinephrine is indicated for (a) Anaphylactic shock www.(a) Centeral nervous system and peripheral nervous system (b) peripheral nervous system only (c) Brain (d) Spinal cord (E) Sympathetic & parasympathetic system 62. Side effect of insulin are (a) Local reaction (b) Hypoglycemia (c) Fat atrophy at the injection site (d) Weight gain (E) All of the above 65.com 151 . Type II diabetes mainly use (a) Insulin (b) Sulphonyl urea (c) Metformin (d) Both B&C (E) All of above 64. Theophylline is (a) Bronchodilator (b) β2 agonist (c) Causes bradycardia (d) All of the above (E) Non of above 67. Which one of these drug is cough suppressant (a) Dextromethorphan (b) Captopril (c) Pilocarpine (d) Dexamethasone (E) Guaifenesin 66.prometric-questions. Type I diabetes use (a) Insulin (b) Glibenclamide (c) Metformin (d) Both A & B (E) None of the above 63. All of these medication are used in epilepsy except (a) Carbamazepine (b) Furosemide (c) Diazepam (d) Phenytoin (E) Gabapentin 73. Captopril is (a) ACE Is (b) Used for treat congestive heart failure www.(b) Asthma (c) Nasal decongestant (d) All of the above (E) Non of above 68.com 151 . Which of the following drug can cause addiction ? (a) Phenobarbitol (b) Tetracycline (c) Iodine (d) Furosemide (E) Acetyl choline 70. All of these medication are general anathesia except (a) Nitrous oxide (b) Diazepam (c) Metronidazole (d) Morphine (E) Thiopental 71.prometric-questions. Which one of these drug used for treatment schizophrenia (a) Chloropromazine (b) Clozapine (c) Haloperidol (d) Risperidone (E) All of them 72. Timolol is indicated for (a) Hypertension (b) Glaucoma (c) CHF (d) Both A&B (E) None of the above 69. Agents used in anemias (a) Ferrous gluconate (b) Vitamine B12 (c) Folic acid (d) All of the above (E) Non of above 78. Antiplatelet drugs (a) Increase bleeding time (b) Aspirin (c) Cloxacillin www. Antianginal drugs (a) Nitroglycerin (b) Isosorbid dinitrate (c) Manitol (d) Both A &B (E) None of the above 76.com 152 .prometric-questions. Diuretics drugs (a) Furosemide (b) Indicated for treatment of hypertension and edema (c) Spironolactone (d) Dorzolamide (E) All of the above 75.(c) CCBs (d) Both A &B (E) None of the above 74. Anticoagulants (a) Reduce formation of fibrin clot (b) Heparin (c) Warfarin (d) Inhibit development of clot (E) All of the above 79. All of these medication are used as antihypertensive except (a) Amlodipine (b) Atenolol (c) Timolol (d) Ferrous gluconate (E) Captopril 77. Selective of the most appropriate antimicrobial agent requires of: (a) The organism identity and sensitivity to particular agent (b) The site of infection (c) The safety of agent and patient factor (d) Pregnancy status (E) All of the above 85. Drugs used in treatment of asthma (a) Aminophylline (b) Beclomethasone (c) Cimitidine (d) Digoxin (E) Both A & B 84.prometric-questions. Aspirin (a) Acetyl salicylic acid (b) Contraindicate in peptic ulcer (c) Used for pain. Penicillin and cephalosporin (a) Major antibiotic that inhibit bacterial cell wall synthesis (b) Called beta-lactams (c) The microbial resistance poses constant challenge to the use of antimicrobial (d) All of the above www. Which of the following belong to NSAIDs (a) Ibuprofen (b) Naproxen (c) Indomethacin (d) Mefenamic acid (E) All of the above 83. inflammation. Drugs for tratment hyperlipidemia (a) lovastatin (b) mebendazole (c) lorazepam (d) none of the above (E) All of above 81.(d) Treat parasitic infection (E) Both A & B 80.com 153 . and fever (d) It is from NSAIDs (E) All of the above 82. Which of the following drug is not antiviral (a) Amantidine (b) Acyclovir (c) Cephalexin (d) Ribovirin (E) Zidovudine www.prometric-questions. Amoxicillin and ampicillin (a) Cell wall synthesis inhibitor (b) Used for treatment of infection caused by gram positive and negative (c) Contraindicated in patient with penicillin hypersensitivity (d) Bactericidal (E) All of the above 87. Which of the following statement is correct about cephalosporin (a) They are classified into four generation (b) Does not used for treatment of UTI (c) Cefoxitin is cephalosporin derivative (d) Both A & C (E) All of above 88.com 154 .(E) Non of above 86. Which one of the following drug is not antifungal (a) Naproxen (b) Amphotericin B (c) Miconazole (d) Nystatin (E) Grisofulvin 91. Ciprofloxacin is (a) Fluroquinolone (b) Bactericidal (c) Inhibit DNA (d) Inhibit G+ve &G-ve bacteria (E) All of the above 90. Protein synthesis inhibitor (a) Tetracycline (b) Gentamycin (c) Clarithromycin (d) Chloramphenicol (E) All of the above 89. Which of the following drug are used for treatment of constipation? (a) Bisacodyl (b) Magnesium sulfate (c) Castor oil (d) Laculose (E) All of the above 96. Drug for treatment peptic and duodenal ulcers: (a) Morphine (b) Rantidine (c) Omeprazole (d) Lorazepam (E) Both B & C 98. Which of the following drugs are disinfectants ? (a) Chlorohexidine (b) Cresol (c) Iodine (d) Hydrogen peroxide (E) All of the above 94.92.com 155 . Drug for treatment of gout (a) Codeine (b) Allopurinol (c) Verapamil (d) Atenolol (E) Pyridoxine 97. Drugs used for treatment of allergies (a) Chloropheneramine maleate (b) Diphenhydramine hydrochloride (c) Indomethacin (d) Nitroglycerin (E) Both A & B 95.prometric-questions. Which of the following drug used for AIDS (a) Metronidazole (b) Zidovudine (c) Metochlopramide (d) Clemastin (E) Flucytosin 93. The therapeutic use of levodopa is www. (a) Angina (b) Anemia (c) Depression (d) Parkinsonian disease (E) Diabetes mellitus 99.com 156 .prometric-questions. The therapeutic use of amitriptyline is (a) Angina (b) Anemia (c) Depression (d) Parkinsonian disease (E) Diabetes mellitus 100 All of the following affect drug distrubtion through lipid bilayer of the cell except (a) Solubility in water (b) Solubility In lipid (c) Relative solubility in water/lipid (d) PH (E) All of above www. prometric-questions.Drugs that produce drowsiness and encourage sleep (hypnosis) a) Hypnotic b) Anti-Migraine c) Antiepileptic d) Anti-Parkinsonism E) Anti-hypertensive 5.Chronic lifelong disorder characterized by recurrent seizures or convulsion a) Epilepsy b) Psychosis c) Narcotics www.Oral drug that reduce anxiety and cause calm (sedation) a) Local anesthesia b) Anti-Depressent c) Sedative d) None of them E) All of above 4.Agent that block nerve conduction producing transient localized loss of sensation a) General anesthesia b) Hypnotic c) Local anesthesia d) None of them E) All of above 3.Exam model 9 1-agent that depress the central nervous system producing loss of consciousness a) Local anesthesia b) Sedative c) General anesthesia d) All of the above E) Non of above 2.com 157 . prometric-questions.Drugs that produce drowsiness with analgesia they are usually addictive a) Narcotic analgesics www.Movement disorder characterized by muscle rigidity. and behavior a) Depression b) Psychosis c) Both A& B d) None of them E) All of them 9.Disturbance of mood manifested by decrease self esteem decreased vitality and Increased sadness a) Depression b) Psychosis c) Epilepsy d) Both A&B E) Non of above 10.Violent involuntary contraction or series of contraction of the voluntary muscles a) b) c) d) E) convulsion Migraine Depression Hypertension None of them 7. tremors and postural instability a) Hypnotic b) Migraine c) Antiepileptic d) Parkinsonism E) Epilepsy 8.com 158 . thought.d) CNS stimulant E) Non of above 6.Group of disorder with disturbance of mood. Drug stimulate both sympathetic and parasympathetic ganglia a) ganglion stimulators b) ganglion blocker www.Agent that block or interfere with sympathetic nervous system a) Sympathomimetic b) Sympatholytic c) Sympathetic antagonist d) Both b and c E) All of above 13.b) antipsychotic c) Epilepsy d) None of them E) All of above 11.prometric-questions.com 159 .Agent when administered will mimic (produce the same effect) of parasympathetic system a) parasympathomimetic b) parasympathetic agonist c) cholinomimetic d) All of them E) Non of above 14.Agent when administered will mimic (produce the same effect) of adrenergic system a) Sympathomimetic b) Sympathetic agonist c) Adrenomimetic d) All of them E) Non of above 12.Agent that antagonize the parasympathetic action a) parasympathomimetic b) parasympatholytic c) parasympathetic antagonist d) both b and c E) All of above 15. Lidocaine a) General anesthesia b) Local anesthesia c) Inhalation anesthesia d) Both a and c www.Agent that reduce skeletal muscle tone a) Sympathomimetic b) parasympathomimetic c) skeletal muscle relaxant d) All of the above E) Non of above 18.com 161 . halothane a) General anesthesia b) Local anesthesia c) Inhalation anesthesia d) Both a and c E) Non of above 19.Thiopental.prometric-questions. ketamine a) General anesthesia b) Local anesthesia c) Intravenous anesthesia D) Both a and c E) Non of above 20.c) Sympathetic agonist d) Both A& C E) Non of above 16.Nitrous oxide.Drug block both sympathetic and parasympathetic ganglia a) ganglion stimulators b) ganglion blockers c) Sympathetic agonist d) Both A& C E) Non of above 17. Drugs chlorpromazine.levodopa a) Antiepileptic b) Antipsychotic c) Antidepressant d) Anti -parkinsonism E) Non of above 25.valproic acid.prometric-questions.E) Non of above 21. carbamazepine is a) Antiepileptic b) Antipsychotic c) Antidepressant d) Narcotic analgesic E) Non of above 24.Phenobarbital a) Sedative b) Hypnotic c) Diuretics d) Both a and b E) None of them 22. haloperidol is belong to a) Antiepileptic b) Antipsychotic c) Antidepressant d) Narcotic analgesic E) Non of above www.diazepam a) Barbiturate b) Benzodiazepine c) Nitrates d) Both a and b E) None of them 23.com 161 . olanzapine a) Typical Antipsychotic b) Atypical Antipsychotic c) Anti -depressent d) None of them E) Both A&B 27.diphenoxylate and Loperamide ……………….com 162 .migraine E) Narcotic analgesic 28.Fluoxetine .prometric-questions.Codeine a) Analgesic b) Central Antitussive c) Control diarrhea d) All of them E) Non of above 31. a) Analgesic www.26.Morphine a) Analgesic b) Central Antitussive c) Control diarrhea d) All of them E) Non of above 30. imipramine a) Antiepileptic b) Antipsychotic c) Antidepressant d) Anti.Amphetamine a) CNS stimulant b) Used in migraine c) Narcotic analgesic d) Used in depression E) A&B 29.clozapine . mepivacaine a) Topical local anesthesia b) Local injection local anesthesia c) Both topical and local injection local anesthesia d) None of the above E) All of the above 35.b) Central Antitussive c) Control diarrhea d) All of them E) Non of above 32.imipramine a) SSRI b) TCA c) MAOI d) CCBs www. sumatriptan a) CNS stimulant b) Used in migraine c) Narcotic analgesic d) A&B E) All of above 33.bupivacaine .com 163 .Fluoxetine a) SSRI b) TCA c) MAOI d) CCBs E) Non of the above 36.Cocaine.prometric-questions. benzocaine a) Topical local anesthesia b) Local injection local anesthesia c) Both topical and local injection local anesthesia d) None of the above E) All of the above 34.Ergotamine. Drug used to eradicate helicobacter pylori bacteria …………….V Thiazide diuretic Paracetamol Protamine sulfate 38.Oral rehydration solution used frequently because a) Has many side effect b) Difficult to use c) Replace water and mineral d) All of the above E) Non of the above 41.com 164 .In case of overdose of warfarin it can antagonize by a) b) c) d) E) Aspirin Vitamin K I.Peptic ulcer drug don’t include …………. a) Diazepam b) Clarithromycin & amoxicillin c) Dapson d) All of the above E) Non of the above 40.E) Non of the above 37..cimitidine has all except : a) Used in gastric ulcer b) H2 receptor antagonist c) No side effect d) All of the above E) Non of the above www. a) Rantidine b) Proton pump inhibitor c) Glycerin d) Omeprazole E) Nizatidine 39.prometric-questions. Omeprazole is a) Used in gastric ulcer b) Laxative drug c) Antifungal drug d) All of the above E) Non of the above 43.Bulk forming laxative …………….Which of the following drug used in gastric ulcer a) Cimitidine b) Omeprazole c) Rantidine d) All of the above E) Non of the above 45.prometric-questions.Drug used in treatment of Hyperlipidemia a) Simvastatin b) Verapamil c) Ketoprofen d) Both A&B E) Non of the above 47.the most important use of H1 receptor antagonist are a) Headache b) Vertigo c) Constipation d) All of the above E) Non of the above 44.Adsorbent antidiarrheal drug a) Kaolin www. a) Bran b) Methylcellulose c) Castor oil d) A and B E) All of above 46.42.com 165 . .Agent that induce vomiting include a) Ipecac b) Amoxil c) Indomethacin d) Paracetamol E) All of the above 49.……………….com 166 .Which of the following cause black staining of stool? a) Ferrous sulfate b) Nitroprusside c) Heparin d) Dipyridamole E) All of the above 52.Used as antidiarrheal drug a) Aspirin b) Loperamide c) Tofranil d) All of the above E) Non of the above 51.prometric-questions.b) Metoclopramide c) Cisapride d) All of the above E) Non of the above 48. Of iron is the cause of iron deficiency anemia a) b) c) d) ↓ intake ↑ requirement ↓ absorption All of the above www.Antidote in excessive bleeding is a) Tranxamic acid b) Metronidazole c) Rifampin d) All of the above E) Non of the above 50. All of them increase action of warfarin except a) Vitamin K b) Aspirin c) Metronidazole d) Sulfonamide E) Non of the above 57.com 167 . Except www. a) Iron deficiency anemia b) Folic acid deficiency anemia c) Pernicious anemia d) Megaloblastic anemia E) All of the above 54.E) Non of the above 53.Which of the following inhibit development of clotting? a) Heparin b) Quinidine c) Nitroglycerin d) Methyldopa E) All of the above 56.Lack of gastric intrinsic factor result in……………..Iron deficiency anemia may occur with a) Pregnancy b) Excess tannic acid c) Bleeding d) All of them E) Non of the above 55.prometric-questions.Which of them consider Fibrinolytic inhibitor (antifibrinolytic?) a) Enoxparin b) Tranexamic acid c) Aminocaproic d) B and C E) All of the above 58.folic acid deficiency due to all of them …. Used to test gallbladder function for diagnostic purpose a) Egg yolk b) Cholecystokinin c) MgSo4 d) All of them E) Non of the above 61.com 168 . stool? a) Aminocaproic acid b) Bismuth subsalicylate c) Triametrene d) Naproxen E) Non of the above 60.prometric-questions.Which of the following cause black staining of tongue. food poisoning d) Diarrhea E) Non of the above 62.Emesis used in toxicity except a) If patient ingested caustic substance b) If patient ingested volatile hydrocarbon c) If patient has CNS depression www.Laxative drug used for the following except a) Constipation b) Arrest bleeding c) Drug.All of the following are dopamine receptor blocker except a) Promethiazine b) Droperidol c) Domperidone d) Piroxicam E) Non of the above 63.a) Lactation b) Lack of vegetable c) Lack of gastric intrinsic factor d) Methotrexate E) Non of the above 59. Which of the following bind to bacterial toxin? a) Tannic acid b) Loperamide c) Kaolin d) Cholestyramine E) All of the above 66.Drugs which increase GIT motility called a) Purgative b) Diuretics c) Prokinetics d) Emetics E) Non of the above www.prometric-questions.d) All of them E) Non of the above 64.………….All of them used in gastric ulcer except a) Famotidine b) Pantoprazole c) Misoprostol d) Phenyl butazone E) Non of the above 68.com 169 .Which of the following used for dissolving gallstone a) ACEI b) CDCA c) UDCA d) B and C E) All of the above 67.block CTZ so prevent emesis a) Ondasetron b) Triametrene c)Oxicam d) Acetaminophen E) Zalcetapine 65. IM is Suitable for………… except (a) Moderate volume of fluid (b) painful irritating drug (c) Anticoagulant (d) Lipid soluble drug (e) Non of the above 74..prometric-questions.……………..com 171 .IV characterized by …. Is proton pump inhibitor a) b) c) d) e) Pantoprazole Rantidine Bismuth subsalicylate Sucralfate All of the above 70..All are true about oral administeration of drug except (a) Chance for treatment of toxicity if happen (b) Easy way for administeration (c) Suitable for emetic cases (d) Low economy in compare other dosage form (e) Non of the above 72.All factor affect drug absosbtion from GIT except (a) Presence of food (b) Another drug (c) The healthy state of intestinal wall (d) Plasma binding protein (e) Non of the above 71..Intradermal injection is Suitable for………… except (a) Sensitivity test (b) painful irritating drug (c) Lipid soluble drug www.except (a) Moderate velocity (b) Suitable for large volume of fluid (c) Suitable for drug suffer from 1st metabolic effect (d) Suitable for painful irritating drug (e) Non of the above 73.69. .Conjugation reaction for drug excretion will lead to (a) Inactive substance (b) More active substance (c) Less active substance (d) More toxic substance (e) No change in active substance 80.The aim of Drug metabolism is to convert the drug into (a) More active substance (b) Less toxic substance (c) More effective substance (d) None of the above (e) All of the above 78.com 171 . except (a) Oxidation reaction (b) Less or none ionized substance (c) Conjugation reaction (d) Reduction reaction (e) Non of the above 79.Drug metabolism include ……..Binding of drug to Plasma binding protein (PBP) of drug characterized by …..Drug metabolism mainly occur in (a) Kidney (b) Colon www.Plasma binding protein (PBP) of drug lead to ……. except (a) Increase t 1/2 (b) Compete similar drug for site of binding to PBP (c) Compete drug with similar inherent substance for site of binding to PBP (d) No medicinal use of this drug (e) Non of the above 76.except (a) Binding site is alpha glycoprotein (b) Binding site gama Globulin (c) Similar drug compete for site of binding to PBP (d) It is reversible process (e) Non of the above 77.(d) Implantation of small tablet under skin (e) Non of the above 75..prometric-questions.. All consider parasympathomimetic except (a) Atropine (b) Carbacol (c) Methacoline (d) Bethanicol (e) All of above 84. All can be used for glaucoma except (a) Neostigmine (b) Carbacol (c) Homatropine (d) Pilocarpine (e) Non of the above 85.prometric-questions. Atropine can used for all of the following except (a) Abdominal spasm (b) Prostate enlargement www. Urine retention can be treated by all of the following except (a) Neostigmine (b) Carbacol (c) Dopamine (d) Methacholine (e) Non of the above 86.Drug excretion mainly occur in (a) Kidney (b) Colon (c) Lung (d) Sweat (e) Intestine 82.Mechanism of excretion of drug through kidney occur through all of them except (a) Drug reabsorption from renal tubule (b) Pass of drug through kidney to urethra (c) Filteration in boman capsule (d) Execretion via career molcule (e) Non of the above 83.(c) (d) (e) Lung Liver Intestine 81.com 172 . One of the following drug used for prostate cancer (a) Medroxy progesterone (b) ethenyl estradiol (c) Testosterone (d) Methionine (e) Carbidopa 90.(c) (d) (e) Motion sickness Parkinsonism Non of the above 87.com 173 . One of the following drug used for treatment of breast cancer (a) Tamoxifen (b) Clomiphen (c) Progestin (d) Methionin (e) Digoxin 89.prometric-questions. Which of the following drug used as anticoagulant both in vivo & vitro (a) Heparin (b) Warfarin (c) Streptokinase (d) None of them (e) All of them www. Atropine side effects include all of the following except (a) Tachycardia (b) Dry mouth (c) Increase secretion of saliva (d) Mydriasis (e) Non of the above 88. prometric-questions.com 174 .Antidote for iron toxicity is a) Desferroxamine b) Protamine sulfate c) I.Oral iron therapy should be in the form of …….V vit K d) Tranaxamic acid E) Non of the above 6.Megaloblastic anemia due to deficiency of a) Vitamin B12 b) Folic acid c) Vitamin B6 d) Both A&B E) Non of the above 3.Parenteral iron therapy include a) Iron dextran complex b) Iron sorbitol c) Ferrous form d) All of the above E) Both A& B 5.Exam model 10 1-aetiology of iron deficiency anemia is a) Decrease intake b) Decrease absorption c) Increase requirement d) All of the above E) Non of the above 2.V vit K www. a) Ferrous form b) Ferric form c) Iron form d) All of the above E) Non of the above 4.Antidote for warfarin toxicity is a) Desferroxamine b) Protamine sulfate c) I. com 175 .V vit K d) Tranaxamic acid E) Non of the above 9.V vit K d) Tranaxamic acid E) Non of the above 8.Antidote for heparin toxicity is a) Desferroxamine b) Protamine sulfate c) I.Heparin a) Anticoagulant b) Antiplatelet c) Fibrinolytic d) Antifibrinolytic E) All of the above 10.warfarin a) Anticoagulant b) Antiplatelet c) Fibrinolytic d) Antifibrinolytic E) All of the above 12.urokinase a) Anticoagulant b) Antiplatelet c) Fibrinolytic d) Antifibrinolytic E) All of the above 11.d) Tranaxamic acid E) Non of the above 7.Antidote for urokinase toxicity is a) Desferroxamine b) Protamine sulfate c) I.prometric-questions.Aspirin a) Anticoagulant b) Antiplatelet c) Fibrinolytic d) Antifibrinolytic www. omeprazole a) H2 receptor antagonist b) Proton pumb inhibitor c) Antacid d) Drugs protect mucosa www.Drugs which inhibit development of clot a) Anticoagulant b) Antiplatelet c) Fibrinolytic d) Antifibrinolytic E) All of the above 16.E) All of the above 13-drugs which inhibit fibrinolysis by inhibit plasminogen activator a) Anticoagulant b) Antiplatelet c) Fibrinolytic d) Antifibrinolytic E) All of the above 14.Antiplatelet drugs include a) Aspirin b) Ticlopidine c) Clopidogril d) All of the above E) Non of the above 18.Drugs which inhibit platelet aggregation a) Anticoagulant b) Antiplatelet c) Fibrinolytic d) Antifibrinolytic E) All of the above 17.Drugs which dissolve thrombus by formation fibrinolytic plasmin a) Anticoagulant b) Antiplatelet c) Fibrinolytic d) Antifibrinolytic E) All of the above 15.prometric-questions.com 176 . E) Non of the above 19.sucralfate a) H2 receptor antagonist b) Proton pumb inhibitor c) Antacid d) Drugs protect mucosa E) Non of the above 22.Drug that may prevent emesis a) Emetic b) Antiemetic c) Purgative d) Antispasmodic E) Laxative 24.rantidine a) H2 receptor antagonist b) Proton pumb inhibitor c) Antacid d) Drugs protect mucosa E) Non of the above 20.Drug that induce reflex vomiting a) Emetic b) Antiemetic c) Purgative d) antispasmodics E) Cathertics www.prometric-questions.Drugs that evacuate bowel is called a) Emetic b) Antiemetic c) Purgative d) antispasmodics E) Anti diarrhea 23.com 177 .Calcium carbonate a) H2 receptor antagonist b) Proton pumb inhibitor c) Antacid d) Drugs protect mucosa E) Non of the above 21. www.prometric-questions. colonic spasm a) Emetic b) Antiemetic c) Purgative d) antispasmodics E) Anti ulcer 26.Phase of acid secretion in which acid secrete will increase is a) Cephalic phase b) Gastric phase c) Intestinal phase d) A&B E) All of the above 29.Drug used for relief painful biliary.Which antacid of the following cause diarrhea as side effect a) Caco3 b) NaHco3 c) Mg salts d) Al(OH)3 E) All of the above 30.com 178 .Calcium carbonate antacid will cause ……………….Which antacid of the following cause alkalosis as adverse effects a) Caco3 b) NaHco3 c) Mg salts d) Al(OH)3 E) Non of the above 31.Ipecac is a) Emetic b) Antiemetic c) Purgative d) Antispasmodics E) Anti diarrhea 27.Phase of acid secretion in which acid secrete will decrease is a) Cephalic phase b) Gastric phase c) Intestinal phase d) A&B E) All of the above 28.25. Which of the following is proton pump inhibitor? a) Caco3 b) rantidine c) lansoprazole d) Al(OH)3 E) All of the above 33.Which of the following is an H2 antagonist a) Caco3 b) rantidine c) lansoprazole d) Al(OH)3 E) All of the above 34.a) diarrhea b) constipation c) Spasm d) Both A& C E) Non of the above 32.C b) I.In case of overdose of warfarin it can antagonize by www.V c) ID d) Both A&B E) Non of the above 37.prometric-questions.the most important oral anticoagulant a) Warfarin b) Rifampin c) Rantidine d) Heparin E) Non of the above 36.Drug that protect mucosa include a) Sucralfate b) Omeprazole c) Rantidine d) All of the above E) Non of the above 35.Heparin is anticoagulant drug usually used by a) S.com 179 . renal damage c.peripheral neuropathy d.myasthenia gravis e.a) Aspirin b) Vitamin K I.com 181 .prometric-questions.biliary obstruction b.dimenhydrate e.metaclopramide b.hemolytic anemia d.increase in plasma cholesterol c.all of the above 39-S/E of INH is a.liver damage b.ketoacidosis 40.V c) Thiazide diuretic d) Paracetamol E) All of the above 38-paracetamol toxicity is a.all of the above www.antiemetic used in emergency room is a.chlorpromazine c.non of the above e.promethazine d. Exam model 11 1-pharmacological effect of NSAIDs include A) Analgesic b) Antipyretic c) Anti inflammatory d) all of the above e) non of the above 2.mefenamic acid a) Non selective C-OX inhibitor b) selective C-OX-1 inhibitor C) Selective C-OX-2 inhibitor d) Non of the above e) All of the above 6-innflammatory arthritis due to deposition of uric acid crystal in joint a) Angina b) Arrhythmia www.rofecoxib a) Non selective C-OX inhibitor b) selective C-OX-1 inhibitor C) Selective C-OX-2 inhibitor d) non of the above e) All of the above 4.Celecoxib a) Non selective C-OX inhibitor b) selective C-OX-1 inhibitor c) Selective C-OX-2 inhibitor d) Non of the above e) All of the above 3.Ibuprofen a) Non selective C-OX inhibitor b) selective C-OX-1 inhibitor C) Selective C-OX-2 inhibitor d) non of the above e) All of the above 5.prometric-questions.com 181 . H.Condition in which cardiac output is less than body need a) Angina b) Arrhythmia c) Gout d) C.prometric-questions.com 182 .H.F e) Psoriasis 7.F e) Psoriasis 10-drug used in treat gout a) Colichine b) allopurinol c) probencid d) sulphinpyrazone e) All of the above 11.H.F e) Psoriasis 8.c) Gout d) C.F e) Psoriasis 9.H.Acute chest pain occurs when coronary blood flow is inadequate to supply The oxygen required by heart a) Angina b) Arrhythmia c) Gout d) C.fuorsemide belong to A) Loop diuretic b) thiazide diuretic c) K-sparing diuretic D) Osmotic diuretic e) Carbonic anhydrase inhibitor www.Abnormal heart beat a) Angina b) Arrhythmia c) Gout d) C. prometric-questions.com 183 .Cardiac glycoside include a) Digitoxin b) digoxin c) quabain D) all of them e) non of them 17.chlorothiazide A) Loop diuretic b) thiazide diuretic c) K-sparing diuretic D) Osmotic diuretic e) Carbonic anhydrase inhibitor 13.12.mannitol A) Loop diuretic b) thiazide diuretic c) K-sparing diuretic D) Osmotic diuretic e) Carbonic anhydrase inhibitor 15.Carbonic anhydrase inhibitor diuretic used in treatment glaucoma a) fuorsemide b) chlorothiazide c) amiloride d) acetazolamide e) spironolactone 16.spironolactone A) Loop diuretic b) thiazide diuretic c) K-sparing diuretic D) Osmotic diuretic e) Carbonic anhydrase inhibitor 14.Route of elimination of digitoxin is a) Renal b) hepatic c) Sweet d) Both A&B www. com 184 .Class III antiarrthymic a) Sodium channel blocker b) Beta blocker c) Potassium channel blocker d) Calcium channel blocker e) Alpha blocker 20.Class II antiarrthymic a) Sodium channel blocker b) b) Beta blocker c) Potassium channel blocker d) Calcium channel blocker e) Alpha blocker 21.prometric-questions.Class I antiarrthymic a) Sodium channel blocker b) Beta blocker c) Potassium channel blocker d) Calcium channel blocker e) Alpha blocker 23.Route of elimination of digoxin is a) Renal b) hepatic c) Sweet d) Both A&B e) non of them 19.e) non of them 18.quinidine a) Sodium channel blocker b) Beta blocker www.Class IV antiarrthymic a) Sodium channel blocker b) Beta blocker c) Potassium channel blocker d) Calcium channel blocker e) Alpha blocker 22. amiodarone a) Sodium channel blocker b) Beta blocker c) Potassium channel blocker d) Calcium channel blocker e) Alpha blocker 26-antihypertensive drug safe in pregnancy a) Methyl dopa b) reserpine c) nitroprusside d) diltiazem e) propranolol 27.captopril is belong to a) Sympatholytic drug b) ACEIs c) CCBs D) Diuretic e) OHGs www.Calcium channel blocker A) Methyl dopa b) reserpine c) Nitroprusside d) diltiazem e) propranolol 28.prometric-questions.c) Potassium channel blocker d) Calcium channel blocker e) Alpha blocker 24.com 185 .verapamil a) Sodium channel blocker b) Beta blocker c) Potassium channel blocker d) Calcium channel blocker e) Alpha blocker 25. Atenolol a) Non selective β blocker b) selective β1 blocker c) Non selective α blocker d) Selective α1 blocker e) Selective β 2 blocker 33.com 186 .prometric-questions.29.Propranolol is a) Centrally acting α2 agonist b) adrenergic neuron blocker c) α blocker d) β blocker e) Calcium channel blocker 31.prazocin is A) Centrally acting α2 agonist b) Adrenergic neuron blocker c) α blocker d) β blocker e) Sodium channel blocker 30.Losartan a) Angiotensin -1receptor blocker b) Diuretic c) ACEIs d) CCBs e) HTN 32.allopurinol a) Decrease uric acid synthesis b) Increase uric acid excretion c) Increase uric acid synthesis d) Decrease uric acid excretion www.Which analgesic is safe during pregnancy? a) Aspirin b) paracetamol c) celecoxib d) Methyl dopa e) Erythromycin 34. simvastatin is used in treatment a) Angina b) Arrhythmia c) Hyper lipidemia d) Hypertension e) Diabetes mellitus 37-atrovastatin is belong to a)Bile acid resin b) HMG-COA inhibitor c) Nicotinic acid derivative d) Fibrates e) sulphonyl urea 38.e) Decrease release of LTB4 35-dopamine is a) Selective β2 agonist b) Selective α1 agonist c) Selective β1 agonist d) Selective α2 agonist e) non of the above 36.com 187 .Condition of high level of cholesterol triglyceride lipoprotein is called A) Angina b) Arrhythmia c) Hyper lipidemia d) Hypertension e) CHF 39.prometric-questions.chlorothiazide cause the following side effects except: a) Hypokalemia b) hyponatermia c) Hypomagnesmia d) ototoxicity e) non of the above www. the action of probencid is antagonized by: A) Phenyl butazone b) Aspirin c) colichicine d) diclofenac e) paracetamol 41.Which of the following drug has anti-androgenic effect? a) spironolactone b) Ammonium chloride c) chlorothiazide d) furesemide www.prometric-questions.Which of the following used in treatment of hypertension a) triametrene b) Hydrochlorothiazide c) ethacrynic acid D) all of the above e) non of the above 45 .com 188 .thiazide diuretic has the following side effects except: a) hypokalemia b) hyponatermia c) hypomagnesmia d) None of the above e) allof the above 43.which of the following used in treatment of glaucoma: a) mannitol b) acetazolamide c) Spironolactone d) Both a+b e) All of above 42.ethacrynic acid causes the following side effects: a) hypokalemia b) ototoxicity c) Hypocalcemia D) all of the above e) non of the above 44.40. e) non of the above 46.com 189 .Pharmacological effect of NSAIDs include A) Analgesic b) Antipyretic c) Anti inflammatory D) all of the above e) non of the above 50 .prometric-questions.in management of paracetamol over dose we can use a) n-acetyl cyctine b) brufen www.which of the following increase the action potential duration: A) Amiodarone b) Ecainamide c) Quinidine d) Both a+c e) All of the above 48.the most important adverse effect of aspirin include a) Gastrointestinal irritation b) Bleeding tendency c) hepatotoxicity d) All of the above e) Both A& B 51.Diuretic drugs include a) furesemide b) adrenaline c) atropine selphate d) aspirin e) metformin 49 .Which of the following drugs prolong duration of action potential? a) quinidine b) digoxine c) Sulindac d) none of the above e) All of the above 47. com 191 .prometric-questions.H.the most important NSAIDs used during pregnancy a) Paracetamol b) indomethacine c) Diflunisal D) all of the above e) non of the above 54 .Drugs used as thiazide diuretic a) chlorothiazide b) Hydrochlorothiazide c) Indepamide d) Non of the above e) All of the above 56.Drug used during acute attack of gout a) Colichine b) indomethacine c) probencid D) all of the above e) non of the above 53 .Condition in which cardiac output is less than body need is a) Congestive heart failure (C.F) b) Arrhythmia c) Angina d) Hypertension e) non of the above www.c) minoxidil d) Atropine e) protamine sulfate 52 .All of the following are adverse effect of ACE inhibitor as (captopril) Except A) Cough b) Eye disturbance c) Taste change d) hyperkalemia e) All of the above 55 . 57.com 191 .the exact description of chemical structure of drug a) Chemical name b) Generic name c) Trade name d) Brand name e) non of above 61 .paracetamol is a) Analgesic b) antipyretic c) anti-inflamatory d) both a+b e) all of the above 58.………. Study of drug and the way they interact with living system A) Pharmacology b) Clinical Pharmacology c) Drug interaction d) Therapeutic e) Toxicology 60 .prometric-questions.Thiopental is a) Inhalation anesthesia b) I.mannitol a) Decrease intracranial pressure b) decrease intraocular pressure c) Treatment glaucoma D) all of the above e) non of the above 59.A drug may have different trade name but only one a) Generic name b) properiarty name c) Brand name d) Both A&B e) All of the above 62 .V anesthesia c) Local anesthesia d) None of the above www.………. Atenolol is a) Selective α1 agonist b) Selective β1 agonist c) Selective α1 blocker d) Selective β1 blocker e) non of the above 64 .Inhalation anathesia is charachterized by a) Difficulet to control B) Used for short term maintenance operation c) Used for hyperlipidemic patients d) None of them e) All of them 66.prometric-questions.You find 20 ml vial of aminophylline with supply labeled 20mg/ml How many mg in the vial a) 200mg b) 400mg c) 600mg d) 800mg e) 1 gm 67.e) All of the above 63 .Salbutamol is used for a) Congestive heart failure b) Bronchial asthma c) hypertension d) none of them e) both A& B 65.You find 20 ml vial of aminophylline with supply labeled 20mg/ml How many ml must to be injected to supply patient with 100mg a) 6 ml b) 10 ml C) 5 ml D) 20 ml e) 25 ml www.com 192 . 68.Convert temperature of 5C to F a) 41 b) 51 c) 31 d) 21 e) 61 73.U To obtain dose of 5000 I.Which of the following belongs to I.Dilute avail of tetracycline for aqueous injection labeled 10000 I.Deciliter is equal A) 10 liter B) 100 liter C) 1000liter D) 1 liter E) non of the above 70 .com 193 .Convert temperature of 50 F to C a) 10 b) 15 c) 20 d) 30 e) 5 72.prometric-questions.Dekagram is equal A) 10 gram B) 100 gram C) 1000 gram D) 1000 mg E) None of the above 69.V anesthesia a) Thiopental b) L-dopa c) adrenaline www.U using water for injection 10 ml a) 4 ml b) 5 ml c) 6 ml d) 7 ml e) non of the above 71 . All of them are NOT inhalation anesthetic drugs.prometric-questions.d) None of them e) All of the above 74. except a) Phenobarbital b) Halothan c) Thiopental d) Diazepam e) Gliclazide 75-Which one of the following oral preparation give the fastest systemic onset of action a) Suspension b) Tablet c) Capsule d) Solution e) Syrup www.com 194 . deficiency of folic acid cause pernicious anemia 3. Nitroglycerin is used as antihypertensive drug 17. Castor oil. C-OX 1 is constitutive form present in many normal tissues 12. Paracetamol inhibit both cox1 and cox2 9. Digitoxin is eliminated by renal elimination 10. Vitamin B12 deficiency due to lack of gastric intrinsic factor result in pernicious anemia 8. Isosorbid dinitrate oral is used in treatment acute attack of angina 16. Nitrate tolerance develop with continuous exposure to nitrate Without interruption www. senna are stimulant laxative 4. C-OX 1 is inducible form produced at site of inflammation 14. Carbenoxolone has antiandrogenic effect 11. Heparin used during pregnancy 6. Guanthidine is antihypertensive of choice for pregnancy 18. Liquid paraffin is irritant purgative 5. C-OX 2 is constitutive form present in many normal tissues 13. In oral therapy should be in ferrous form 7.prometric-questions.com 195 .Put true or false for the following question 1. iron sorbitol is oral iron 2. Parcetamol over dose antidote is N-acetyl cystiene 15. Castor oil is considered as lubricant purgative 24. Antihyperlipidemic agent increase level of HDL 26. Aspirin increase effect of anticoagulant 27. Cimitidine has antiandrogenic effect 21. Spironolactone cause gynecomastia 28.prometric-questions. Example of NSAIDs is indomethacine www. Rantidine used to treat diarrhea 22. Antihyperlipidemic agent increase level of LDL 25. Peptic ulcer is a disease of respiratory centre 23.com 196 . Heparin used as long term anticoagulant 20.19. Answer of Exam model 1 12345678910111213141516171819202122232425- C A A C A E B C A A E A A A D C C D B A D D B D A 26272829303132333435363738394041424344454647484950- www.prometric-questions.com C D C B C D E C A B B C C C B A B E B A A B A A E 51525354555657585960616263646566676869707172737475197 B A B C B E B B A D D A B A D B A A A B D A B C E 767778798081828384858687888990919293949596979899100- B B C B D D D E D C A B E C E D B E A C A C D A B . Answer of Exam model 2 12345678910111213141516171819202122232425- D E E E A B D E C D A D E C B E D B A E D E B A A 26272829303132333435363738394041424344454647484950- www.prometric-questions.com B A D A C B A A C A A D A B E E A E D D E E E D B 51525354555657585960616263646566676869707172737475198 D A C B A C B D C A E E B E E E C A D D A E A E A 767778798081828384858687888990919293949596979899100- E B C D E A A B D B A D A A B B A B D A A A A C D . Answer of Exam model 3 12345678910111213141516171819202122232425- B E C D C B C B D A E E B C D B D D C D D E E A E 26272829303132333435363738394041424344454647484950- www.com E D B A E D B D B C A D D D A C E B D D E C E E D 51525354555657585960616263646566676869707172737475199 C A E E B B B A A D A C A D C E B C E D C A C C A 767778798081828384858687888990919293949596979899100- E C B D D A A C E C E A E D C E D C C C C B C C A .prometric-questions. Answer of Exam model 4 12345678910111213141516171819202122232425- D D C A E D A C A C B D E B E B D A C B E A E A B 26272829303132333435363738394041424344454647484950- www.com C E A B B D C B C D E B C A E D A E E C A C E C E 51525354555657585960616263646566676869707172737475211 C A B A B C D A C B C D A B E B C E A C D A D B B 767778798081828384858687888990919293949596979899100- B C B D C A D D B B A C E C A C A A A D C B D A D .prometric-questions. com D E B C C D B D C A E A C E D E D B C B D A A D D 51525354555657585960616263646566676869707172737475211 E D D B D C B D A B C B E C A E A C E D B D A A D 767778798081828384858687888990919293949596979899100- A D B B A C E C D E E E C A E D E E E E D B E D A .Answer of Exam model 5 12345678910111213141516171819202122232425- A E B A E D E C E C B C D A A D A D C A E B C C D 26272829303132333435363738394041424344454647484950- www.prometric-questions. prometric-questions.com E E B A D C E D D E C D A B B C A D A C D D D C A 51525354555657585960616263646566676869707172737475212 B B D B B D D D D A C C D B C A C E D B B D D E B 767778798081828384858687888990919293949596979899100- E A D B A B C C D D C C D D E C A D B D D A A C D .Answer of Exam model 6 12345678910111213141516171819202122232425- A E C B D E C E A D E A E C B E A E A D C B E D D 26272829303132333435363738394041424344454647484950- www. prometric-questions.com E E E B A C B D E E A C B C A B B C B E D B B D C 51525354555657585960616263646566676869707172737475213 D B c D A C B E E C B C D B E C C A A A D E A C D 767778798081828384858687888990919293949596979899100- C D D E B E E E C A D D A B E E D E C E B E A D C .Answer of Exam model 7 12345678910111213141516171819202122232425- C B D B A D B A D D D C E A E D E A A E D C B E C 26272829303132333435363738394041424344454647484950- www. prometric-questions.Answer of Exam model 8 12345678910111213141516171819202122232425- C B D A D C C D D B B C A D D E B A D C D D B D A 26272829303132333435363738394041424344454647484950- www.com D D D C B C A D C D B D B A D D E C C B C E C A C 51525354555657585960616263646566676869707172737475214 C D A C D C E B C D A A D E A A D B A C E B D E D 767778798081828384858687888990919293949596979899100- D D E E A E E E E D E D E E A C B E E E B E D C A . Answer of Exam model 9 12345678910111213141516171819202122232425- C C C A A A D B A A D D D D A B C A A B D B A D B 26272829303132333435363738394041424344454647484950- www.prometric-questions.com B C A D B C B A B A B B C B C C A B D D A A A A B 51525354555657585960616263646566676869707172737475215 A D C D A A D C B D B D D A C D D C A D C A B B A 767778798081828384858687888990919293949596979899100- A B B A D A A A C C B C A C A . prometric-questions.Answer of Exam model 10 12345678910111213141516171819202122232425www.com D D A E A C B D A C A B D C A B D B A C D C B A D 26272829303132333435363738394041424344454647484950216 A C D C B B C B A A A B E C E . Answer of Exam model 11 1234567891011121314151617181920212223242526- D C C A A C D B A E A B C D D D B A C B D A A D C √ 2627282930313233343536373839404142434445464748495027- www.com A D B C D A B B A C C B C D A D D D D A A D A D A √ 5152535455565758596061626364656667686970717273747528217 A D A B E A D D A A A B D B D B C D D B A A A B D √ 12345678910111213141516171819202122232425- × × √ × √ √ √ √ × √ √ × × √ × × × √ √ √ × × × × √ .prometric-questions.
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